International journal of biochemistry and biophysics最新文献

{"title":"Seasonal Variations in the Bacteriological Parameters of Boreholes Water in Emene, Enugu State, Nigeria","authors":"Nzekwe Chidimma MaryAnn, O. Chinedu","doi":"10.13189/ijbb.2024.120201","DOIUrl":"https://doi.org/10.13189/ijbb.2024.120201","url":null,"abstract":"","PeriodicalId":93301,"journal":{"name":"International journal of biochemistry and biophysics","volume":"79 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141715012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dynamic Surface Tension Study of Solid Nanoparticles Adsorption at a Water/Oil Interface","authors":"Papa Mady Sy, Nicolas Anton, S. Dieng, A. Djiboune, L. Diouf, B. Ndong, G. Mbaye, Thierry Vandamme, M. Diarra","doi":"10.13189/ijbb.2024.120101","DOIUrl":"https://doi.org/10.13189/ijbb.2024.120101","url":null,"abstract":"","PeriodicalId":93301,"journal":{"name":"International journal of biochemistry and biophysics","volume":"37 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140276316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effective Bioassay for Vinegar Production Using African Star Apple (Chrysophyllum albidum G. Don) by Enzymatic Catalysis and Acetic Bioconversion","authors":"Audray Vodounou, E. S. Adjou, Kowiou Aboudou, Fréjuce M. Kplaïssa, E. Ahoussi, Daniel Chougourou, A. Yessoufou, Lamine Baba-Moussa, D. C. Sohounhloué","doi":"10.13189/ijbb.2023.110201","DOIUrl":"https://doi.org/10.13189/ijbb.2023.110201","url":null,"abstract":"","PeriodicalId":93301,"journal":{"name":"International journal of biochemistry and biophysics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46908537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Thermal Stability Profile of Aflatoxins from Fungal Isolates from Dried Fishes","authors":"Azudiugwu Obianuju Sabina, George-Okafor Uzoamaka, O. Chinedu","doi":"10.13189/ijbb.2023.110202","DOIUrl":"https://doi.org/10.13189/ijbb.2023.110202","url":null,"abstract":"","PeriodicalId":93301,"journal":{"name":"International journal of biochemistry and biophysics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42130324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Spectrum of Hemoglobinopathies and Thalassemia Trait Using HPLC: Hospital-Based Observational Study in Northern India","authors":"S. Shah, A. Bansal, Siddhant Gautam, K. Gupta, R. Das, D. Mehta","doi":"10.13189/ijbb.2023.110101","DOIUrl":"https://doi.org/10.13189/ijbb.2023.110101","url":null,"abstract":"","PeriodicalId":93301,"journal":{"name":"International journal of biochemistry and biophysics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42320975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Phenol Sulfotransferase (SULT1A1) Ligand Binding Order","authors":"J. Beckmann, B. Schultz, B. Doyle","doi":"10.13189/ijbb.2022.100201","DOIUrl":"https://doi.org/10.13189/ijbb.2022.100201","url":null,"abstract":"","PeriodicalId":93301,"journal":{"name":"International journal of biochemistry and biophysics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43195724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Proteomics of Lipid Transport Proteins and Assessment of Oxidative Stress Parameters in Acute Ischemic Stroke and Healthy Control","authors":"E. Maria, Meenu Yohannan, H. T., Mathew John","doi":"10.13189/ijbb.2022.100101","DOIUrl":"https://doi.org/10.13189/ijbb.2022.100101","url":null,"abstract":"","PeriodicalId":93301,"journal":{"name":"International journal of biochemistry and biophysics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48945820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green Synthesized Nanomaterials: An Analysis of the Impact on Cellular Processes, Gene Regulation, and Epigenome","authors":"N. Khatik","doi":"10.13189/ijbb.2021.090201","DOIUrl":"https://doi.org/10.13189/ijbb.2021.090201","url":null,"abstract":"Green synthesis of nanoparticles has gained prominence in recent years as a cost-effective and environmentally sustainable approach. This green nanotechnology has diverse applications, and their potential impact on cellular processes needs to be thoroughly examined via nanomaterials. One of the major challenges in this field is the alleviation of oxidative damage, cytotoxicity, and genotoxicity induced by nanoparticles. Lately, research is more focused on analyzing the epigenetic effects including DNA methylation and histone modifications mediated through the alteration in microRNA expression that is influenced by nanoparticles. Due to their physical and chemical properties, these nanomaterials are extremely suitable carriers of targeted modifications in gene regulatory systems. Delivery of silencing RNAs and artificial transcription factors built on nanoparticles for modulating gene expression has been extensively reported in recent years. Studies on various cell lines have confirmed the downstream effects of these changes in gene expression, as demonstrated by the significant alteration in expression of proteins functional in a multitude of pathways, such as those associated with oxidative stress, cytoskeletal proteins, molecular chaperones, proteins involved in energy metabolic processes, and apoptosis and tumor-related proteins. This reshuffling of molecular expression has also been corroborated by investigations at genomic, transcriptomic, proteomic, and metabolomic levels. This chapter highlights the detailed mechanism of modulation of gene regulation and expression, and the cytological and molecular changes caused by these bionanomaterials. The toxicological aspects and biocompatibility impacts of these nanoparticles, which are of paramount importance while considering their biomedical and environmental applications, have also been outlined.","PeriodicalId":93301,"journal":{"name":"International journal of biochemistry and biophysics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41626355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutritional, Functional and Microbiological Analysis of Powdered Seed of Moringa oleifera","authors":"A. A. Ibiene, Nelly C. Ekwuribe, Anwuli U. Osadebe, P. Okerentugba","doi":"10.13189/ijbb.2021.090101","DOIUrl":"https://doi.org/10.13189/ijbb.2021.090101","url":null,"abstract":"This study looked to establish the proximate composition, mineral content, water absorption capacity, energy values and microbial load of the seeds of Moringa oleifera following processing. The study was carried out using standard physicochemical and microbiological techniques. Proximate analysis revealed that M. oleifera seed powder was rich in protein (34.39%) and fat (37.76%). The mean crude fibre, ash and carbohydrate values were 5.93% and 9.42% respectively while moisture was relatively low at 7.40%. The water absorption capacity, gross energy and metabolisable energy levels were determined as 428.01%, 509.67 Kcal/100g and 398.22 Kcal/100g respectively. The heavy metal levels were low to negligible but the calcium and phosphorus levels were somewhat high at 437.85 mg/kg and 525.10 mg/kg respectively with a ratio of 0.834. Counts of 1730 CFU/g and 121 CFU/g were obtained for total heterotrophic bacteria and total fungi. The fungi and bacteria obtained were Rhizopus stolonifer , Aspergillus niger , Bacillus , Staphylococcus aureus , Pseudomonas aeruginosa , Proteus and Micrococcus luteus . No coliforms were recorded. The results from this study established M. oleifera seed powder as a good source of energy, protein, fat, calcium and phosphorus amongst other minerals and nutrients. Its nutritional and mineral content support coagulation/ flocculation and use in livestock and aquaculture feed.","PeriodicalId":93301,"journal":{"name":"International journal of biochemistry and biophysics","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41719393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Signature of Glycylglutamic Acid Structure.","authors":"Amanda Hoff,&nbsp;Nigam Rath,&nbsp;John Lisko,&nbsp;Matthias Zeller,&nbsp;Ganesaratnam K Balendiran","doi":"10.13189/ijbb.2021.090102","DOIUrl":"10.13189/ijbb.2021.090102","url":null,"abstract":"<p><strong>Background: </strong>Glutamate (Glu) is of great interest in biomedical research. It is considered a biomarker in diabetes, which may potentially contribute to the development of autism in genetically vulnerable human populations, and it is found in relation to advanced glycation end products (AGEs) [1]. Additionally, Glu plays an active role in the function of ligand-gated ion channel glutamate receptors, chloride channels capable of filtering glutamate, as well as Potassium (K⁺)-channel [2]. Glu attains α [3] and β [4] crystal forms and Cβ-CH2 show asymmetric ¹H signal pattern in NMR spectra.</p><p><strong>Objectives: </strong>The current study was undertaken to understand the signal patterns of Cβ-CH₂ in Glu of the smallest dipeptide, Glycylglutamic Acid (GlyGlu), as well as the order, and planarity of the amide bond in the molecule.</p><p><strong>Materials and methods: </strong>NMR spectra of GlyGlu were measured in D₂O to deduce ¹H and ¹³C chemical shifts and coupling constants. GlyGlu was crystallized from MeOH and the structure was determined by single crystal X-ray diffraction techniques.</p><p><strong>Results: </strong>The sidechain of Glu in the dipeptide dissimilates the β form. The amino group of Gly (Glycine) is protonated and exhibits hydrogen bonding with the main chain carboxylate group of a symmetry-related Glu that is deprotonated in the crystal packing of GlyGlu. The deprotonated main chain carboxylate of Glu is also in hydrogen-bonding distance from the side chain carboxylic acid group that is in the protonated form of a symmetry-related Glu of the dipeptide. The Cβ-CH₂ geminal protons on the side chain of Glu have different chemical shifts and splitting pattern in ¹H NMR reflecting their dissymmetric environment.</p><p><strong>Conclusion: </strong>The results reported will be useful for monitoring changes that Glu and/or molecules in connection to Glu may undergo in <i>in vivo</i>, <i>in situ</i>, and <i>in vitro</i> conditions. This provides a valuable metric which will enable the examination of the metabolites relevant to the detection and diagnosis of disease or developmental conditions, as well as scrutinizing the effectiveness of treatment options.</p>","PeriodicalId":93301,"journal":{"name":"International journal of biochemistry and biophysics","volume":"9 1","pages":"8-15"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e7/a8/nihms-1742723.PMC8515908.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39527179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}