Annals of pulmonary and critical care medicine最新文献

{"title":"Adenosine triphosphate infusion in patients with cancer pain: a pilot study","authors":"A. Karelov, A. A. Ryazankina, E. Khokhlova, G. Vasilieva, V. A. Semkichev","doi":"10.21320/1818-474x-2021-4-115-121","DOIUrl":"https://doi.org/10.21320/1818-474x-2021-4-115-121","url":null,"abstract":"Introduction. About 50-66 % patients with cancer suffered from intensive pain when are given analgesics. Objectives. We investigated the effectiveness of intravenous infusion of non-selective purine receptors agonist adenosine triphosphate in cancer patients with moderate and severe pain who had being received non-selective inhibitor of cyclooxygenase plus weak opioid tramadol. Materials and methods. Sixty-seven patients in which pain sensations were localized in different regions were scheduled for the study. The intravenous infusion of adenosine triphosphate 3545 mcg kg(-1) min(-1) was performed within the period from 100 to 160 minutes. Pain severity was estimated by numeric verbal scale where “0” - no pain and “10” - maximal pain. Moreover, we studied prognostic significance of the original scale that was based on patient’s ability to pointed out precisely the pain sensation margins where “1” - patient can specify exactly the margins of pain sensations on the skin; “2” - patient can indicate approximately zone with pain sensation (periarticular tissue or bone or big muscle); and “3” - patient can determine large anatomical region only. Analysis of correlations was performed between scale value and the effectiveness of adenosine triphosphate infusion. Results. We revealed that 79 % (53 out of 67) patients have pointed out to pain relief after infusion with more than 20 % reduction of pain intensity (p = 0.0000001 - Wilcoxon signed rank test). As results, we obtained statistically correlation link (p = 0.02 - gamma-test and p = 0.02 - Kendall tau rank correlation coefficient) between the adenosine triphosphate infusion effectiveness and pain type with high precision of the pain sensation margins. Conclusions. Intravenous infusion of adenosine triphosphate has the high effectiveness for pain relief in cancer patients particularly when pain sensation margins high precisely detected to be.","PeriodicalId":93261,"journal":{"name":"Annals of pulmonary and critical care medicine","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87761078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early oral feeding after subtotal esophagectomy with immediate esophageal reconstruction as a component of ERAS protocol. A prospective randomized study","authors":"M. Raevskaya, N. Kovalerova, D. Ruchkin, M. Yan, G. Plotnikov","doi":"10.21320/1818-474x-2021-2-103-114","DOIUrl":"https://doi.org/10.21320/1818-474x-2021-2-103-114","url":null,"abstract":"","PeriodicalId":93261,"journal":{"name":"Annals of pulmonary and critical care medicine","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88257590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modern approaches to the diagnostics, treatment and prevention of severe community-acquired pneumonia in adults: a review","authors":"S. Avdeev, B. Z. Belotserkovskiy, A.V. Dehnich, A. Zaytsev, R. Kozlov, D. Protsenko, S. Ratchina, A. Sinopalnikov, S. Yakovlev, A. Yaroshetskiy","doi":"10.21320/1818-474x-2021-3-27-46","DOIUrl":"https://doi.org/10.21320/1818-474x-2021-3-27-46","url":null,"abstract":"","PeriodicalId":93261,"journal":{"name":"Annals of pulmonary and critical care medicine","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84384564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of the outcome of severe polytrauma in children: a retrospective cohort multicenter study","authors":"K. V. Pshenisnov, Y. Aleksandrovich, A. Lipin, V. A. Kaziakhmedov, M. U. Kozubov, N. K. Pastukhova","doi":"10.21320/1818-474x-2021-4-69-78","DOIUrl":"https://doi.org/10.21320/1818-474x-2021-4-69-78","url":null,"abstract":"Introduction. Severe polytrauma is the most common cause of deaths in children, but there are currently no objective criteria for predicting the outcome of severe polytrauma in pediatric ICU patients and identifying a high-risk group. Objectives of the study is to identify the features of clinical and laboratory status and intensive care measures in children with severe polytrauma, which determine the outcome of a critical condition. Materials and methods. Design: A retrospective cohort multicenter uncontrolled study. 230 children were examined. The age of patients was 9.5 (4-14) years. The score on the Abbreviated Injury Score (AIS) was 34 points, the Pediatric Traumatic Score (PTS) - 5 (2-8) points. As a primary outcome, the duration of control mechanical ventilation and ICU length of stay were evaluated. Secondary outcome was divided into recovery, presence of neurological deficiency and death. Results. Minimum duration of treatment in ICU is noted with shortterm sedation during the day, an AIS score of less than 30 points and a PTS score of more than 5 points. The presence of intracranial hematoma (ICH) is associated with a doubling of treatment duration in ICU. The maximum statistically significant difference in mean values was revealed when assessing the effect on the outcome of the following features: catecholamine index (F = 109.4; p = 0.000); transfusion volume of freshly frozen plasma (F = 42.0; p = 0.000) and transfusion volume of erythrocytes (F = 33.4; p = 0.000). Conclusions. The need for prolonged sedation, an AIS score of more than thirty points, a PTS score of more than five points, and the presence of ICH is associated with an increase ICU length of stay and adverse outcome. The use of high doses of catecholamines and massive blood transfusion on the first day of treatment in ICU are independent predictors of the death of polytrauma in children.","PeriodicalId":93261,"journal":{"name":"Annals of pulmonary and critical care medicine","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83325346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of volemic status in postpartum period: a pilot prospective cohort study","authors":"A. Ronenson, E. Shifman, A. V. Kulikov","doi":"10.21320/1818-474x-2021-3-88-97","DOIUrl":"https://doi.org/10.21320/1818-474x-2021-3-88-97","url":null,"abstract":"","PeriodicalId":93261,"journal":{"name":"Annals of pulmonary and critical care medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78717080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative analysis of the safety of hypnotic component of anesthesia in robot-assisted radical prostatectomy: a review","authors":"I. Lutfarakhmanov, N. A. Zdorik, S. Lazarev, I. R. Galeev, E. Syrchin, A. Lifanova, P. Mironov","doi":"10.21320/1818-474x-2021-3-117-125","DOIUrl":"https://doi.org/10.21320/1818-474x-2021-3-117-125","url":null,"abstract":"","PeriodicalId":93261,"journal":{"name":"Annals of pulmonary and critical care medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89762951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Forecast of the medical evacuation in patients with the cardiovascular dysfunction. A retrospective study","authors":"A. S. Minin, N. P. Shen, D. Tretyakov, I. D. Panov","doi":"10.21320/1818-474x-2021-2-136-142","DOIUrl":"https://doi.org/10.21320/1818-474x-2021-2-136-142","url":null,"abstract":"","PeriodicalId":93261,"journal":{"name":"Annals of pulmonary and critical care medicine","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81509195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lung ultrasound in COVID-19 pneumonia: comparison with computed tomography. An observation prospective clinical trial","authors":"R. E. Lakhin, E. A. Zhirnova, A. Shchegolev, O. Jovanikic, I. Zheleznyak, I. Menkov, V. Salukhov, A. A. Chugunov","doi":"10.21320/1818-474x-2021-2-82-93","DOIUrl":"https://doi.org/10.21320/1818-474x-2021-2-82-93","url":null,"abstract":"Introduction. Pneumonia is the most severe form of the new coronavirus infection (COVID-19). The large area of damage and the high mortality rate in COVID-19 pose the challenge of rapid bedside diagnosis and dynamic monitoring of the volume and nature of lung tissue damage. Objectives. The goal of the study was to compare the data obtained with computed tomography and ultrasound of the lungs, as well as the accuracy of ultrasound segmentby-segment verification of damage zones in patients with pneumonia caused by SARS-CoV-2. Material and methods. The observational prospective clinical study included 388 patients aged 18-75 years;with a confirmed diagnosis of pneumonia caused by COVID-19 or suspected COVID-19. Lung ultrasound was performed within 24 hours after computed tomography (CT) of the chest. During the CT scan, pathological signs, infiltration, and consolidation of the lungs were determined, which were recorded by lung segments. Ultrasound of the lungs was performed according to the “Russian Protocol”, ultrasound signs in the lines and consolidation were also recorded based on the projection of the lung segments on the chest wall. An analysis was performed to describe and generalize the distributions of variables. The sensitivity and specificity of ultrasound methods were evaluated with ROC analysis against CT as a “gold standard”. Results. Bilateral involvement was found in 100 % of cases. Typical signs of pneumonia caused by coronavirus infection on CT were a “ground glass” pattern, thickened pleura, consolidation, reticular pattern, and a “crazy paving” pattern. During ultrasound examination of the lungs and pleura, the detected signs corresponded to the signs of CT. B-lines (multifocal, discrete, or confluent) and consolidation of various volumes of lung tissue were most frequently encountered during ultrasound. The sensitivity of ultrasound of the lungs in the accuracy of the segment-by-segment diagnosis of damage by the sign of infiltration is 87.9 %, and the specificity is 91.5 % (the area under the ROC curve is 0.939;p < 0.001). The sensitivity of the ultrasonic sign of consolidation was 84.6 %, and the specificity was 79.2 % (the area under the ROC curve is 0.846;p < 0.001). Conclusions. The use of ultrasound of the lungs during the COVID-19 allows us to identify and assess the volume and nature of lung damage. Thus, lung ultrasonography has demonstrated accuracy comparable to chest CT in detecting lung damage in patients with COVID-19. © 2021, Practical Medicine Publishing House LLC. All rights reserved.","PeriodicalId":93261,"journal":{"name":"Annals of pulmonary and critical care medicine","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78326219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Delivery of Gaseous Nitric Oxide to the Extracorporeal Circulation Circuit: Experimental and Clinical Data: a review","authors":"V. Pichugin, A. Bautin, S. Domnin, M. Ryazanov, E. Sandalkin","doi":"10.21320/1818-474x-2021-3-108-116","DOIUrl":"https://doi.org/10.21320/1818-474x-2021-3-108-116","url":null,"abstract":"","PeriodicalId":93261,"journal":{"name":"Annals of pulmonary and critical care medicine","volume":"371 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84966418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of severity assessment scales in evaluating the transportability of newborns: a cohort retrospective study","authors":"R. Mukhametshin, N. S. Davydova","doi":"10.21320/1818-474x-2021-4-98-105","DOIUrl":"https://doi.org/10.21320/1818-474x-2021-4-98-105","url":null,"abstract":"Introduction. Standardized assessment of the patient status and the decision on the possibility of transfer is an essential part of the neonatal transport service. However, there are no generally accepted tools for assessing severity and making decisions regarding newborn transfer. Objectives. To compare the capabilities of scales in relation to the decision about the non-transportability of newborns. Materials and Methods. The cohort study included data from 604 trips of the transport team of the neonatal resuscitation and consultation center. The assessment was carried out on the KSHONN, NTISS and TRIPS scales, the distribution of transportable and non-transportable patients was studied depending on the assessment for each scale. The calculation of the risk ratio of nontransportation was performed depending on the assessment on the scales. AUC ROC was calculated for all scales in relation to the decision of transport team about the patient’s non-transportability. Results. The scores on the scales significantly differ between the subgroups of transportable and non-transportable newborns, p < 0.0001. Significant differences in subgroup distribution were observed depending on the scores between transportable and nontransportable patients. When evaluated by KSHONN 6-8 points, the risk ratio of non-transportability was 61.36 [3.77-999.47]. For NTISS of 20-29 points, the risk ratio of non-transportability was 51.37 [3.18-829.11]. When evaluated by TRIPS 17-23 points, the risk ratio of nontransportability was 18.81 [1.09 - 327.26]. Conclusions. Scales have a high predictor value in relation to the decision of the transport team about the non-transportability of patients. Comparison of the subgroups by the proportion of non-transportable patients indicates that a score of more than 5 according to the KSHONN, more than 19 points on the NTISS scale and more than 16 points on the TRIPS scale are associated with a significant increase in the risk of non-transportability.","PeriodicalId":93261,"journal":{"name":"Annals of pulmonary and critical care medicine","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91156978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}