EC clinical and medical case reports最新文献

{"title":"Postoperative Facial Nerve Palsy in a Pediatric Patient.","authors":"Cindy B Yeoh,&nbsp;Kathleen J Lee,&nbsp;Luis E Tollinche","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Peripheral nerve injury is a well-recognized complication of surgery and anesthesia. However, overall incidence is less than 1% [1,2]. Most commonly affected nerves include the ulnar nerve, brachial plexus, and lumbosacral nerve root [2]. Postoperative facial nerve palsy as a complication of surgery and anesthesia has been documented in the literature, but it is a rare event [3]. The occurrence of any type of nerve injury as a postoperative complication is even less common in the pediatric population [2,3]. In this report, we describe a case of postoperative facial nerve palsy in a pediatric patient after a thoracotomy..</p>","PeriodicalId":93173,"journal":{"name":"EC clinical and medical case reports","volume":"4 5","pages":"36-38"},"PeriodicalIF":0.0,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802996/pdf/nihms-1727402.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39756427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of secondary hyperparathyroidism in a patient on hemodialysis with parathormone levels within the targets and high total alkaline phosphatase","authors":"Jessica Kachmar, Caroline Albert, M. Dupuis, B. Imbeault, M. Vallée","doi":"10.15761/cmr.1000160","DOIUrl":"https://doi.org/10.15761/cmr.1000160","url":null,"abstract":"Chronic kidney disease related mineral and bone disorders (CKD-MBD) cause significant morbidity and mortality. Guidelines for treatment and prevention of CKD-MBD have put focus on the treatment of secondary hyperparathyroidism in patients on hemodialysis by maintaining levels of parathormone (PTH) between 2 to 9 times the upper normal limit. However, levels of PTH are not always accurately correlated to the degree of bone remodeling, and some patients may suffer from hyperparathyroidism though their PTH levels are within the targets. Therefore, it is important to identify other bone markers that could help us adequately assess bone status in these patients, such as total alkaline phosphatase (TALP). In this case report, we describe a patient who suffered from poorly controlled hyperparathyroidism with very high levels of TALP despite having PTH levels within the targets. TALP could thus be an important bone marker and should be taken into consideration complementary to PTH when evaluating the bone status of a patient on dialysis.","PeriodicalId":93173,"journal":{"name":"EC clinical and medical case reports","volume":"9 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91431081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A red tumor on the wrist. How useful is the dermoscopy: A case report","authors":"I. Al Faker, Soukayna Kabbou, F. Marraha, Najlae Rahmani, Youness Benyamna, S. Gallouj","doi":"10.15761/cmr.1000161","DOIUrl":"https://doi.org/10.15761/cmr.1000161","url":null,"abstract":"","PeriodicalId":93173,"journal":{"name":"EC clinical and medical case reports","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84693755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early asymptomatic arrythmia detection using intermittent ECG in the diagnostic process – A case report","authors":"Krista G. Austin, R. Carter Iii, B. Reilly","doi":"10.15761/cmr.1000159","DOIUrl":"https://doi.org/10.15761/cmr.1000159","url":null,"abstract":"Introduction: Asymptomatic arrythmias can result in adverse events including sudden cardiac death. Bradycardia is prevalent in active populations and can remain asymptomatic or become malignant. Pauses of six seconds in duration and syncope are the present criterion recommended for treatment. To the best of our knowledge, this is the first report supporting the use of intermittent ECG monitoring to identify an asymptomatic arrythmia associated with bradycardia which resulted in eventual placement of a pacemaker. Case presentation: The subject matter is a 31-year-old male recreational athlete who took chest and thumb ECGs intermittently throughout a 2-day period. On both days, abnormal rhythms were identified more than once in one of the leads. Follow up diagnostics included a 24-hour Holter revealing 6 isolated action potential durations, 2 isolated pre-ventricular contractions, 6 supraventricular ectopic beats, 2 ventricular ectopic beats, 28 bradycardic events and 18 pauses. At 6 month follow up, an insertable loop recorder identified 117 events with 112 pauses and 5 bradycardic events. Eleven of the pauses were of >6 seconds duration. A near syncope episode including symptoms of tunnel vision, nausea, diaphoresis and almost loss of consciousness resulted in hospitalization. The ECG at time of hospitalization showed normal sinus rhythm with ST-segment elevation and tall T waves. A dual chamber pacemaker was placed to prevent future episodes of syncope. Conclusion: The present case study highlights the need for additional objective criteria to identify patients requiring early management of asymptomatic bradycardia to prevent unnecessary hospitalization. Intermittent ECG assessment may provide an additional complimentary assessment which can regularly be utilized to monitor patients with asymptomatic arrythmia. De-conditioning may not be an option for treatment and waiting for syncope to occur leaves patients susceptible to sudden cardiac death or mortality as a result of uncontrollable circumstances at time of a near syncope episode. Development of additional monitoring processes and criteria for early pacemaker implantation are warranted.","PeriodicalId":93173,"journal":{"name":"EC clinical and medical case reports","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88608217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simple Green Changes for Anesthesia Practices to Make a Difference.","authors":"Cindy B Yeoh,&nbsp;Kathleen J Lee,&nbsp;Vanja Coric,&nbsp;Luis E Tollinche","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The environmental debate on going green in the operating room (OR) has been a controversial topic for many years. Challengers of greening efforts cite various obstacles and arguments against these initiatives. However, ORs in the United States continue to generate a staggering amount of waste daily. In this article, we review major barriers to going green and highlight simple, yet effective greening strategies that anesthesia practices could adopt to reduce our carbon footprint.</p>","PeriodicalId":93173,"journal":{"name":"EC clinical and medical case reports","volume":"3 12","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808258/pdf/nihms-1647000.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38831256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integration of active specific immunotherapy and cell therapy into the protocols of biomedical management of interstitial pneumonia with autoimmune features – A case study","authors":"R. Moya, Mike K. S. Chan, M. Wong, D. Klokol","doi":"10.15761/CMR.1000158","DOIUrl":"https://doi.org/10.15761/CMR.1000158","url":null,"abstract":"Non-specific interstitial pneumonia (NSIP) is the second most common morphological and pathological pattern of interstitial lung diseases. A significant proportion of patients with interstitial lung disease (ILD) manifest autoimmune features consisting, among others, of a morphologic domain with multi-compartment involvement and specific autoantibodies, as well as association to other autoimmune pathologies, such as systemic lupus erythematous, rheumatoid arthritis and Hashimoto thyroiditis. The symptoms of non-specific interstitial include insidious onset of dyspnea and dry cough with a restrictive pattern of decreased lung function and reduced gas exchange capacity. Corticosteroids, anti-fibrotics and immunosuppressants are the classical protocol to treat the condition, but management should be carefully individualized due to the wide heterogeneity of IPAF and lack of evidence in this particular subgroup of patients. The multidisciplinary immunological approach with xenogeneic and/or autologous peptides and its derived immune extracts might be a way to induce autoimmune tolerance, based on the anergy mechanism of secretion of immunomodulatory cytokines, such as IL-10 and transforming growth factor- β (TGF- β ) and T-regulatory cells. Here we report a clinical case of 47 years old woman with IPAF and organized pneumonia (OP) with rheumatic complications addressed integrativelly with the autologous Active Specific Immunotherapy (ASI), xenogeneic peptide immunotherapy, ozone autohemotherapy and nutritional antioxidants perfusion. The integrative biomedical program was run from July 2019 until February 2020 with stabilization of lung degeneration and compliances, consequent modulation of chronic inflammation, progressive reduction of dry cough and joint pain, less fatigue, better sleep quality, overall energy and further decreasing of pharmaceutical’s dosage. This article opens a scientific discussion on how to address positively to chronic autoimmune conditions within the use of biomedical multifunctional and natural tools like autologous and xenogeneic immunotherapy in combination with a more conservative pharmaceutical protocol.","PeriodicalId":93173,"journal":{"name":"EC clinical and medical case reports","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73832753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and safety evaluation of Brillia patients with Attention-Deficit/Hyperactivity Disorder","authors":"T. Allen, Rashash Dhoalokia, Sylvia Johnson-Park, Giridhar Mnv, Naveed Basha Court","doi":"10.15761/cmr.1000155","DOIUrl":"https://doi.org/10.15761/cmr.1000155","url":null,"abstract":"Background: Attention-Deficit/Hyperactivity Disorder (ADHD) is one of the most common neurodevelopmental disorders in children. It is usually first diagnosed in childhood and often lasts into adulthood. Children with ADHD will have trouble paying attention, controlling impulsive behaviors, or be overly active. The hallmarks are hyperactivity, impulsivity, and inattention that are beyond reasonable developmental expectations for a child's age. The science behind Brillia is based on a new way to combine homeopathy and antibody science. The active ingredient of Brillia, Lapine S-100 immune globulin, is produced using antibodies to the brainspecific S-100 protein (S-100B). This protein is an essential regulator of many different intracellular and extracellular brain processes, e.g., various enzyme activities, calcium homeostasis, communication between neurons, etc. Thus, the clinical study of the efficacy of Brillia for Children for the treatment of anxiety disorders, disturbances of behavior, and attention, accompanied by increased excitability, irritability, and hyperactivity, are very important and promising. To determine the efficacy of Brillia for Children for the treatment of anxiety disorders, disturbances of behavior, and attention, accompanied by increased excitability, irritability, and hyperactivity in children, two clinical studies were carried out. Methods: A double-blind, randomized placebo-controlled study of Brillia evaluating clinical efficacy and safety for children with attention deficit hyperactivity disorder was conducted. Prior to inclusion in the study, the patients or their legal guardians were provided with information about the study and signed an informed consent form. Patient information collected during the study is strictly confidential. *Correspondence to: Timothy Allen, Global Allied Pharmaceuticals, Center for Excellence in Research and Development, 160 Vista Oak Dr. Longwood, FL 32779, USA, E-mail: timallenmed69@gmail.com","PeriodicalId":93173,"journal":{"name":"EC clinical and medical case reports","volume":"60 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84605365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preclinical and preliminary clinical reports for successful treatment of ovarian cancer with standard treatments in combination with epigenetic modifiers in a complimentary and integrative approach","authors":"M. Nezami, J. Garner","doi":"10.15761/cmr.1000143","DOIUrl":"https://doi.org/10.15761/cmr.1000143","url":null,"abstract":"","PeriodicalId":93173,"journal":{"name":"EC clinical and medical case reports","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85063999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and safety evaluation of Brillia in patients with Anxiety Disorder","authors":"T. Allen, Rashash Dhoalokia, Sylvia Johnson- Park, Giridhar Mnv, Naveed Basha Court","doi":"10.15761/cmr.1000154","DOIUrl":"https://doi.org/10.15761/cmr.1000154","url":null,"abstract":"Background: According to the American Psychiatric Association, anxiety disorders are the most common type of psychiatric disorder. Many patients with anxiety disorders experience physical symptoms related to anxiety and subsequently visit their primary care providers instead of psychiatrists. Despite the high prevalence rates of these anxiety disorders, they often are under-recognized and undertreated clinical problems. According to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V), anxiety disorders include disorders that share features of excessive fear, anxiety and related behavioral disturbances. These disorders include separation anxiety disorder, selective autism, specific phobia, social anxiety disorder (social phobia), panic disorder, agoraphobia, generalized anxiety disorder, substance/medication-induced anxiety disorder, and anxiety disorder due to another medical condition. Brillia uses the combined sciences of homeopathy and antibodies, which is a new way of treatment. The active ingredient of Brillia, Lapine S-100 immune globulin, is produced using antibodies to the brain-specific S-100 protein (S-100B), which acts as an essential regulator for many different intracellular and extracellular brain processes. To establish the clinical efficacy of Brillia for the treatment of anxiety disorders, the conduct of clinical study was relevant. Thus, to determine the efficacy and safety of Brillia for the treatment of anxiety disorders and Attention-Deficit/Hyperactivity Disorders, two clinical studies were designed for each indication. One such clinical research on the patients with anxiety disorders is explained in this article, and results from the other clinical study on the patients with Attention-Deficit/Hyperactivity Disorder is described in another publication/section. Methods: A double-blind placebo-controlled randomized study of Brillia evaluating clinical efficacy and safety for children with anxiety disorders. Before the patients were recruited in the study, the patients of the legal guardians of the patient were explained about the study and signed informed consent was received. Any patientrelated information that was collected during the conduct of the research is handled confidentially. Prior to inclusion in the study, the patients or their legal guardians were provided with information about the study and signed an informed consent form. Patient information collected during the study is strictly confidential. *Correspondence to: Timothy Allen, Global Allied Pharmaceuticals, Center for Excellence in Research and Development, 160 Vista Oak Dr. Longwood, FL 32779, USA, E-mail: timallenmed69@gmail.com","PeriodicalId":93173,"journal":{"name":"EC clinical and medical case reports","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89474410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Invitro and invivo correlation of biomarker response to epigenetic therapy in pancreatic cancer","authors":"M. Nezami","doi":"10.15761/cmr.1000149","DOIUrl":"https://doi.org/10.15761/cmr.1000149","url":null,"abstract":"","PeriodicalId":93173,"journal":{"name":"EC clinical and medical case reports","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88147525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}