Journal of clinical research and reports最新文献

{"title":"Irreversible Electroporation of Carcinoma of the Prostate Gland with a Focus on Localized Carcinoma of the Prostate Gland: A Review and Update","authors":"A. Venyo","doi":"10.31579/2690-1919/239","DOIUrl":"https://doi.org/10.31579/2690-1919/239","url":null,"abstract":"Even though adenocarcinoma of the prostate gland could be lethal in its advanced stage, adenocarcinoma of the prostate gland can be effectively treated when the carcinoma is localized to the prostate gland and when the localized adenocarcinoma is a low-risk or intermediate-risk localized adenocarcinoma of the prostate gland. it is localized. Traditionally, radical prostatectomy (RP) or radical radiotherapy (RT) in the form of either external beam radiotherapy or brachytherapy were utilized to treat all men who have localized adenocarcinoma of the prostate gland as treatment of curative intent. Nevertheless, Radical prostatectomy and radical radiotherapy do tend to be associated with significant risks of post-treatment side effects. Some patients who have localized prostate cancer may not be medically fit as a result of their comorbidities to undergo radical prostatectomy or radical radiotherapy to their prostate cancers. Over recent years a number of less-invasive treatment options are being utilized for the treatment of some localized adenocarcinomas of the prostate gland and some of the treatment options include: Cryotherapy of prostate Cancer; Radiofrequency ablation of prostate cancer, High Intensity Focused Ultrasound Treatment of Prostate Cancer and Irreversible Electroporation of prostate cancer as focal ablation or whole gland ablation. Focal therapy has emerged as a potential form of treatment that can achieve similar oncological outcomes to radical treatment while preserving functional outcomes and decreasing rates of adverse effects. Irreversible electroporation (IRE) is one such form of focal therapy which utilizes pulsatile electrical currents to ablate tissue. This modality of treatment is still in an early research phase, with studies showing that IRE is a safe procedure that can offer good short-term oncological outcomes whilst carrying a lower risk of poor functional outcomes. Irreversible Electroporation (IRE) is a new radiology image-guided tissue ablation which does induce cell death through very short but strong electric fields. IRE had been demonstrated to have preserving properties towards vessels, nerves, as well as the extra-cellular matrix. For this reason, IRE could represent an ideal treatment option for adenocarcinoma where other treatment options including radical prostatectomy and radical radiotherapy tend to unselectively destroy that encompass the prostate cancer and inducing side effects including urinary incontinence as well as sexual dysfunction / impotence. Some results of studies in which IRE had been utilized for the treatment of curative intent of localized low-risk and intermediate-risk adenocarcinomas of the prostate gland had indicated complete efficacy of IRE to the standard of radical prostatectomy and standard radical radiotherapy with regard to the 5-year tumour recurrence rate as well as better preservation of genitourinary function which did prove the safety as well as suitability of IRE for the tr","PeriodicalId":93114,"journal":{"name":"Journal of clinical research and reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49468692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differences among Obese versus Nonobese Patients undergoing total Laparoscopic Hysterectomy. A single Center Experience","authors":"Flaviu Ionut Faur","doi":"10.31579/2690-1919/236","DOIUrl":"https://doi.org/10.31579/2690-1919/236","url":null,"abstract":"Aim of the study: The main aim of this study is to analyze the influence of obesity over the intraoperative and post-operative evolution, in the context of total laparoscopic hysterectomy. Material and Methods: The study developed in the II nd Surgical Clinic of the “Pius Brinzeu” County Emergency Hospital Timișoara between 1st of January 2017 – 1st of January 2019 and it was applied to a general batch of 29 women patients diagnosed with benign pathology of the uterus and adnexa. Results: The general batch we considered necessary some type of categorization of the women patients based on the BMI: Group A: BMI = 19.5-24,9kg/m2; Group B: BMI = 25-29.9 kg/m2; Group C: BMI> 30kg/m2. A positive moderated co-relation between the number of the comorbidities and the BMI (r=0.493, p˂0.05). Somehow self-explanatory, it was emphasized the fact that group B and C which contained mostly patients with the BMI limit over the usual one, it was remarked a proportional increase of the comorbidities at the same time with the increase of the BMI. A strong positive co-relation between the BMI and the intervention time (p=0.047), therefore, those two being tied by proportional increase relation. In this way we obtained a statistically significant co-relation between BMI and the post-operative complications (p˂0.05) but with a low number of major complication on the general batch. Conclusions: By analyzing the comorbidities and the post-operative evolution, minor differences were encountered between the study groups, and it was demonstrated that there is no reason to see a high BMI level as an obstacle in performing TLH.","PeriodicalId":93114,"journal":{"name":"Journal of clinical research and reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46006758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differential Profile of High-Performance Adults with Attention Deficit Hyperactivity Disorder","authors":"Pablo L. López, T. Testa","doi":"10.31579/2690-1919/238","DOIUrl":"https://doi.org/10.31579/2690-1919/238","url":null,"abstract":"Objective: To compare the neurocognitive profile of a subgroup of patients with ADHD who have a high academic-occupational functioning vs. patients with low functioning. Method: A total of 50 adults with ADHD, 10 with high academic-occupational functioning (ADHD/HF), 20 with low academic-occupational functioning (ADHD-LF), and 20 healthy controls were assessed with a standard neuropsychological battery. Independent sample tests and logistic regression were calculated to compare the performance of the three groups and to identify predictor variables. Results: Statistically significant differences were found in the forward digits subtest between the subtypes of ADHD, but not between ADHD-HF and controls, nor between controls and ADHD-LF. In matrix reasoning subtest, significantly lower performances were registered between both ADHD groups compared to the control group. In the letter number subtest, ADHD-LF obtained a significant lower performance than the control group, but the ADHD-HF group do not differ with the other two groups. Finally, regarding to the binary logistic regression analysis, it could be observed that the only variable that best predicted belonging to these groups has been forward digits, which according to the data of the model would be a protection factor. Conclusion: The profile of patients with high socio-occupational performance was characterized by a better conservation of working memory and the capacity for sustained attention, and a lower tendency to distraction.","PeriodicalId":93114,"journal":{"name":"Journal of clinical research and reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44441174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Concurrent validity of Grau’s Experiential Self-Report Transdiagnostic Test Modified for a more Comprehensive Assessment of the Affective Dimension","authors":"Humberto García Penedo","doi":"10.31579/2690-1919/237","DOIUrl":"https://doi.org/10.31579/2690-1919/237","url":null,"abstract":"Based on the qualitative Self-Report Experiential test of Grau, modifications were made to increase its psychometric potential. The modifications were based on the transdiagnosis and from the integral affective dimension that included negative and positive emotions. A construct validation had already been carried out on the modifications. The trait anger construct was validated with the State-Trait Anger Expression Inventory STAXI-2,Depression with the Goldberg Trait-State Depression Inventory (IDERE),Anxiety with the Goldberg Trait-State Anxiety Inventory (IDARE);each one with its Cuban version. A significant positive (moderate) Spearman’s correlation (rho) of rs=0.438 was obtained between the Self-Report Anxiety construct and the IDARE, as well as a sensitivity of 83.3% versus 100% of the IDARE. A significant positive (moderate) Spearman’s Rho correlation of rs=0.459 between the self-report depression construct and the IDERE. The sensitivity of this construct was 73.3% in the Self- report compared to a sensitivity of 90% in the IDERE. The specificity of the Self- report for depression was 26.7% while in the IDERE it was 90%. The correlation of anger in the Self-Report with the STAXI-2 was rs=0.558 (significant, positive and moderate). While the sensitivity for anger was 46.7% and the specificity 53.3%. A remarkable degree of concurrence was concluded between Anxiety, Depression and Anger of Experiential Self-Report with the corresponding tests compared in a sample of 30 apparently healthy subjects. Self-report becomes a psychometric integration instrument that provides the diagnosis of anxiety, depression, anger, Alexithymia, emotional self-control, estimation of psychological trauma, a measure of positivity, emotional health and a coding of emotions. According to their clinical significance, which makes it easier to correlate them with other study variables.","PeriodicalId":93114,"journal":{"name":"Journal of clinical research and reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44765223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of COVID-19 on the clinical picture and therapy of Bipolar I Disorder Maniacal Episode","authors":"Nadir A. Aliyev, Zafar N. Aliyev","doi":"10.31579/2690-1919/235","DOIUrl":"https://doi.org/10.31579/2690-1919/235","url":null,"abstract":"Objective: The purpose of this study was a retrospective study of the contingent of Impact of COVID-19 on the clinical picture and therapy of Bipolar I Disorder maniacal episode who were most infected with COVID-19. Materials and Methods: We study 150 patients Bipolar I Disorder who infected with COVID-19 impact on the clinical picture and therapy of the illness. The investigation ware carried out in psychiatric hospital Ministry of Health of the Republic of Azerbaijan. The hospital has a capacity of 2000 beds. Results: patients with Bipolar I Disorder who infected with COVID-19 in these clinically observed following changes: the intensity of psychopathological symptoms increased, psychosomatic balancing occurs, that is, during the COVID-19 illness, Bipolar I Disorder symptoms fade into the background, practically prevalence maniacal faze become intensively. Conclusion: patients Bipolar I Disorder who infected with COVID-19 in these clinically observed shows psychotic maniacal faze become intensively.","PeriodicalId":93114,"journal":{"name":"Journal of clinical research and reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44458090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgıcal Management of Crohn Dısease ın Chıldren: A Revıew Artıcle","authors":"Volkan Sarper Erikci","doi":"10.31579/2690-1919/232","DOIUrl":"https://doi.org/10.31579/2690-1919/232","url":null,"abstract":"Crohn’s disease (CD) is an inflammatory bowel disease with chronic transmural inflammation of the intestinal wall. It can be observed from oral cavity to anus and it typically involves the ileum, ileocecumor portions of the entire colon. With an increasing rate of CD in children, surgery still has a role in the management of this entity in children when medical treatment is unsuccessful. In this review article it is aimed to review the surgical treatment of CD under the light of relevant literature. During the management of children with CD, risks and benefits of surgical options should be carefully assessed and an appropriate surgical intervention should be performed promptly in order to avoid future complications and to gain future growth of the child with an acceptable quality of life.","PeriodicalId":93114,"journal":{"name":"Journal of clinical research and reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45722508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Notes to the Report, An Element of Great Importance to understand the Pathological Diagnosis","authors":"F. J. T. Gómez","doi":"10.31579/2690-1919/231","DOIUrl":"https://doi.org/10.31579/2690-1919/231","url":null,"abstract":"I would like to propose a game to you. Let´s go to a hospital, no matter which one you have chosen. Visit the different services or units. Observe and write down how many and what kind of books populate the libraries of the different specialists. Make a summary and classify the findings in relation to the number of copies and theme. With few exceptions, you will find a very curious fact.","PeriodicalId":93114,"journal":{"name":"Journal of clinical research and reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47901450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plasma Therapy Gains Attention in Treatment of Viral Infections, Dermatological Illness, and Orthopedic Illnesses","authors":"Ashish M. Gujrathi","doi":"10.31579/2690-1919/234","DOIUrl":"https://doi.org/10.31579/2690-1919/234","url":null,"abstract":"Plasma therapy is one of the major chapters in medicines. Convalescent plasma therapy, another term for plasma therapy involves the use of blood from a person who has recovered from a particular illness to help others who are suffering from the same disease. The plasma of this blood is likely to contain antibodies that can help other patients fight the same illness, especially if viruses or pathogens are compromising the immunity system. Plasma therapy speeds up the recovery and helps manage symptoms. Moreover, it is used in wound healing, face rejuvenation, and androgenetic alopecia. It can help patients suffering from Covid-19, which increased its demand since the Covid-19 outbreak.","PeriodicalId":93114,"journal":{"name":"Journal of clinical research and reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46631243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incisional Hernia following Abdominal Surgery in Children: A Single Centre Experience","authors":"Chukwubuike Kevin Emeka, Anijunsi Livinus Patrick, Onah Livinus Nnanyereugo","doi":"10.31579/2690-1919/233","DOIUrl":"https://doi.org/10.31579/2690-1919/233","url":null,"abstract":"Background: Although uncommon, incisional hernia is a well-known complication of abdominal surgery in children and data on incisional hernia in the pediatric age group are sparse. The aim of this study was to evaluate a single center’s experience with regards to the incidence and outcome of incisional hernia in children. Materials and Methods: This was a retrospective study of children aged 15 years and younger who developed incisional hernia following abdominal surgery, between January 2013 and December 2017, at the pediatric surgery unit of a tertiary hospital in Enugu, Nigeria. Results: During the study period, a total of 1004 pediatric abdominal surgeries were performed. Out of this number, 31 patients developed incisional hernia: This accounted for an incidence rate of 3.1%. There was male predominance and the mean age at diagnosis of incisional hernia was 24 months. All the patients presented with a protrusion at or around the site of a previous surgical scar. Non-operative treatment (serial bandaging) was effective in most of the patients. There was no mortality. Conclusion: Incisional hernia is a well-known complication of abdominal surgery. This study recorded the incisional hernia incidence rate of 3.1%. Non-operative treatment was successful in majority of the patients. Future studies should emphasis on the specific risk factors (surgeon/patient) that may predispose to incisional hernia.","PeriodicalId":93114,"journal":{"name":"Journal of clinical research and reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43819725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and Validation of “Divorcing the Self-Incompatible Scale” (DSIS)","authors":"Ebrahim Khodadady, Sholeh Bagheri","doi":"10.31579/2690-1919/230","DOIUrl":"https://doi.org/10.31579/2690-1919/230","url":null,"abstract":"Background: Divorce has become an individualistic as well as collective problem in all societies requiring a sound theory and statistics to address it explanatorily and empirically. Objective: Almost all studies in various fields of knowledge have addressed divorce categorically. The present study was, however, designed to explore it as a cognitive domain by resorting to psychiatry, psychology, and religion and schema theory. Methodology: Several male and female individuals who were divorcing or divorced were interviewed to develop the 30-item divorcing the self-incompatible scale (DSIS). The scale was then administered to 548 divorcing and/or divorced selves (DDS) and their responses were subjected to Principal Axis Factoring and Promax with Kaiser Normalization to specify what factors underlie the scale. Results: The 30 items comprising the DSIS loaded acceptably on eight factors representing the cognitive families of Having Various Conflicts, Prioritizing Personal Interests, Having No Principles, Having No Decency, Having Different Tastes, Social Media Addiction, No Marital Education, and Misunderstanding Married Life. The families correlated significantly not only with each other but also with the DSIS representing the domain of divorce. Conclusion: Divorce is a cognitive domain through which the DDS reveal their self-theistic, polytheistic or practicing monotheistic selves.","PeriodicalId":93114,"journal":{"name":"Journal of clinical research and reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44118183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}