Journal of clinical research and reports最新文献

{"title":"Pseudo-Subdural Collection on Ultrasound: A Mirror Image Artefact","authors":"Khalaf Saba","doi":"10.31579/2690-1919/270","DOIUrl":"https://doi.org/10.31579/2690-1919/270","url":null,"abstract":"Teaching point: -Extra-calvarial subcutaneous or subgaleal collection can mimic as subdural collection on ultrasound due to mirror image artefacts.","PeriodicalId":93114,"journal":{"name":"Journal of clinical research and reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42369422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiological Aspects of the Management of Heart Failure Patients Seen in Cardiological Consultations in the National Hospital of Niamey","authors":"H. Idrissa","doi":"10.31579/2690-1919/266","DOIUrl":"https://doi.org/10.31579/2690-1919/266","url":null,"abstract":"Background/Aim: Heart failure is defined as a structural or functional abnormality of the heart resulting in an inability to supply the tissues with oxygen at a rate commensurate with their needs. Objective: To contribute to a better knowledge of the epidemiological aspects of the treatment of in charge of patient’s heart failure patients. Materials and Methods: This is a prospective, cross-sectional study conducted over a period of 6 months (February 2020 to October 2020 without April et May due to Covid) Result: Thus, our sample consisted of 300 cases. The average age was 56.9 +13.7 years with extremes ranging from 19 to 98 years. Housewives were the most represented at 43.7%. High blood pressure and sedentary lifestyle were the most common DRFs in 95% of the patients, followed by obesity in 22.3%. In 61.3% of the cases, patients knew they had heart disease but did not know the type. Unusual shortness of breath on exertion was the main sign that prompted patients to consult a doctor (67.7%). Only 2% weighed themselves regularly. All of our patients (99%) were aware of the recommendation for sodium restriction and more than half (58.3%) had adapted to a low-salt diet. Only 23.2% of our patients drank less than 1.5L per day. 29.7% of our patients were not physically active. Regarding treatment, diuretics were the most used as specific treatment in 64.3% of cases and antiplatelet agents in 12.3% of cases. Conclusion: Our study has highlighted educational gaps in the heart failure population. Further studies may help to initiate a therapeutic education approach for patients in order to improve their quality of life and Morbi-mortality.","PeriodicalId":93114,"journal":{"name":"Journal of clinical research and reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42354700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Profile of Congenital Cardiopathies in Paediatric Departments A and B of the National Hospital Niamey National Hospital (Research article)","authors":"H. Idrissa","doi":"10.31579/2690-1919/267","DOIUrl":"https://doi.org/10.31579/2690-1919/267","url":null,"abstract":"Aim: The aim of this study was to determine the extent of congenital heart disease in the population of children, for a better management and prevention strategy. Materials and Methods: This was a descriptive and cross-sectional study over a period of 4 years 10 months from January 2016 to October 2020 (retrospective over 4 years and prospective over 10 months) at the National Hospital of Niamey; Were included in our study all patients aged 0 to 21 with congenital heart disease confirmed by cardiac ultrasound who were hospitalized or monitored externally. Our data were analyzed by Epi Info software in version 7.2.2.6. 24. Descriptive and analytical statistics were used: the mean with standard deviation (SD) (for normal distributive variations), odds ratio (OR) and the median (Me) for the description of asymmetric distributive values. The comparison of the proportions was also carried out; to do this we used the statistical test of chi2. The test is significant if p <0.05 Results: The gender ratio was 1.005 in favour of men. The median age of our patients was 16.8 months with extremes ranging from 0 months to 247 months, the most represented age group is 29 days to 24 months with 81.1%. The majority of our patients (62.4%) came from urban areas, parental consanguinity was present in 42.2% of cases. 55.3% of our patients had reported a notion of recurrent respiratory infection. Respiratory distress was found in 29.5% of cases, followed by fatigue during feedings (16.7%). Tachycardia was found in 72.2% of our patients, 49.6% were undernourished. Heart murmur was found in 80.3% of our patients, 4.4% had Down's syndrome. Cardiomegaly was found in 64.4% of our patients, 15.7% had pulmonary hypervascularization. CIV was found in 27.03% followed by T4F, CAV, and CIA with 20.39 respectively; 17.20 and 16.95%. Surgery was indicated in 68.3%. Anemia was found in 55% of our patients, 49.6% had hyperleukocytosis. Antibiotic treatment was started in 72.7% of cases, 31.2% had benefited from diuretics, 23.8% from iron supplementation, 10.3% was on beta blockers. 18.7% had received surgical treatment, PAH and endocarditis were found in 1 and 0.73% of cases, respectively. 34.1% were awaiting surgery. The recorded death rate was 27.3%. Conclusion: Congenital heart disease is becoming more and more frequent and constitutes a very important health problem in our pediatric departments. They are dominated by CIVs and T4s. The diagnosis and their management are still difficult due to the lack of diagnostic and therapeutic means.","PeriodicalId":93114,"journal":{"name":"Journal of clinical research and reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44123366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Overview of Oxytocin: Chemical Structure, Receptors, Physiological Functions, Measurement Techniques of oxytocin, and Metabolism","authors":"Azab Elsayed Azab","doi":"10.31579/2690-1919/256","DOIUrl":"https://doi.org/10.31579/2690-1919/256","url":null,"abstract":"Background: Oxytocin is a peptide hormone comprising 9 amino acids. It is produced in the hypothalamus and stored and secreted by the posterior lobe of the pituitary gland and synthesized in other organs such as the uterus, ovaries, placenta, heart, blood vessels, skin, kidneys, and testis. Receptors of oxytocin are present on myoepithelial cells, heart, blood vessels, macrophages, thymus, pancreas, kidneys, and adipocytes. Objectives: The current review aimed to give highlight the oxytocin structure, receptors, physiological functions, measurement techniques, and metabolism. Oxytocin is a small peptide that consists of nine amino acids in a six–amino acid ring formed by cysteine bonds and a three–amino acid tail with a terminal amine. It is synthesized in brain regions that are critical to behavioral and physiologic homeostasis. Oxytocin is involved in uterine contraction during labor and ejection of milk during breastfeeding and plays a role in social behavior, emotions love and affection, the period after childbirth, and metabolic functions. The action of oxytocin in facilitating human bonding and social relation is well known. The effects of Oxytocin on metabolism and food intake suggesting its potential effects in treating obesity. The half-life time of oxytocin in the brain is triple as long as its half-life time in the periphery. The sensitivity and density of oxytocin receptors increase during labor. After birth, the neonatal baby sucks on his mother's breast, causing the release of milk by stimulating hypothalamic neurons to produce oxytocin. Oxytocin neurons have been heavily implicated in mediating sexual behavior in both humans and animals. The social memory was enhanced by central oxytocin administration in male rats. The action of oxytocin affects social memory in multiple brain regions, including the ventral hippocampus, amygdala, olfactory bulb, and lateral septum. Oxytocin neurons may mediate MC4R-driven sexual behavior in male mice. MC4R signaling in oxytocin neurons permits ejaculation. A decreased latency to ejaculate in rabbits and rats after administration of oxytocin. The effect of oxytocin receptor ligands on the ejaculatory response may be due to the modulation of dopamine serotonin neurotransmission. Oxytocin lowers the threshold for the initiation of maternal behavior but is not involved in its maintenance. The oxytocin and the melanin-concentrating hormone (MCH) systems may interact to modulate maternal behavior. Oxytocin regulates maternal- or mating-regulated mood. Initial measurements of oxytocin by using radioimmunoassay and bioassays suggested that oxytocin concentration in blood is very low, 5 pg/ml, with small increases as pulses,15 pg/ml, during lactation and uterine contractions. Variations in oxytocin concentration, especially in rapid response to specific experiences, such as anticipation of breastfeeding, sexual stimulation, exercise, affiliative social contact, and psychologic stress. Oxytocin is rapidly r","PeriodicalId":93114,"journal":{"name":"Journal of clinical research and reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41922110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of Some Organic Ammonium Formate Salts and Study of Their Antifungal Properties","authors":"Ramadan Ali Bawa","doi":"10.31579/2690-1919/257","DOIUrl":"https://doi.org/10.31579/2690-1919/257","url":null,"abstract":"This work is concerned with the preparation of a number of organic ammonium formate salts (or ionic liquids; ILs) throughout a reaction between the formic acid and some aliphatic and aromatic amines including the ammonia. Five organic ammonium formate salts were formed, some of them were in the form of solid salts and others were as the ionic liquids (ILs) at room temperature. The yields of the prepared organic salts ranged from (21%) to (79%). However, some attempts towards the preparation of other fifteen organic salts were not successful. The resulting five organic ammonium formate salts/ionic liquids were characterized using a number of spectroscopic techniques such as the infrared (IR), the nuclear magnetic resonance spectroscopy (1HNMR) and the mass spectrometry (ms). The collected spectroscopic data confirmed the formation of theses organic ammonium formate salts. The antifungal properties of the prepared organic ammonium formate salts were investigated against the aspergillus niger (A. niger), and the antifungal results were compared with the antifungal effect of the commercially available antifungal agent Daktarin, which was used as a reference in this study.","PeriodicalId":93114,"journal":{"name":"Journal of clinical research and reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47707262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oncology Information Systems: New Product Launches and Collaborations to Improve Quality of Care","authors":"Ashish M. Gujrathi","doi":"10.31579/2690-1919/254","DOIUrl":"https://doi.org/10.31579/2690-1919/254","url":null,"abstract":"The increase in prevalence of cancer, availability of different types of cancer treatments, and efficient management of treatment led to the development of oncology information systems. Clinics, healthcare organizations, and hospitals began utilization of oncology information systems for management of the entire treatment.","PeriodicalId":93114,"journal":{"name":"Journal of clinical research and reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47729850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Airway Foreign Bodies in Children: A Review Article","authors":"Volkan Sarper Erikci","doi":"10.31579/2690-1919/250","DOIUrl":"https://doi.org/10.31579/2690-1919/250","url":null,"abstract":"Foreign body aspiration (FBA) in children represents a significant morbidity and even mortality producing sudden deaths. Regarded as a major public health issue, FBA may be the end result of aspiration of various organic and inorganic materials. Parental and public awareness including preventive measures is important in avoiding these injuries. The consequences of FBA may pose great challenge for both the children, their families together with clinicians dealing with these children. In this review article it is aimed to discuss the epidemiology, clinical presentations, diagnosis and treatment modalities of FBA in children under the light of relevant literature.","PeriodicalId":93114,"journal":{"name":"Journal of clinical research and reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43667805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevention of Smoking in Scholarship Students of the Faculty of Medical Sciences of Artemisa","authors":"Jorge Félix Rodríguez Hernández","doi":"10.31579/2690-1919/252","DOIUrl":"https://doi.org/10.31579/2690-1919/252","url":null,"abstract":"Introduction: Young people expose dissimilar reasons as justification for tobacco consumption. The presence of smoking in university students studying medicine and nursing becomes a challenge for institutional authorities, in their purpose of solving the health problem. Objective: to design an action plan for the prevention of smoking in scholarship students of the Faculty of Medical Sciences of Artemisa. Methods: a descriptive, prospective longitudinal study was developed with 211 smoking scholarship students from the aforementioned entity in the period from January 20 to March 25, 2020. Procedures were used such as: documentary review, observation, survey, focus group, brainstorming, and cause and effect diagram. Results: 22 causes were identified that favored the increase in smoking, six correspond to strategic and organizational gaps; seven are related to teachers; five correspond to the methodological teaching process and four are linked to educational work. Likewise, an action plan focused on seven objectives, 18 activities and four indicators was developed to evaluate the implementation process. Conclusions: The smoking prevention strategy applied to smoking scholarship students at the Faculty of Medical Sciences of Artemisa does not ensure the reduction of this toxic habit, which is potentially vulnerable with the proposed action plan.","PeriodicalId":93114,"journal":{"name":"Journal of clinical research and reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41977142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Vitro Antibacterial Effect of Essential Oil and Two Extracts of Myrtus Communis Leaves","authors":"Rim M. Harfouch","doi":"10.31579/2690-1919/251","DOIUrl":"https://doi.org/10.31579/2690-1919/251","url":null,"abstract":"Our study aims at evaluating the efficacy of extracts and essential oil of Myrtus communis leaves from the Syrian coast against several bacterial strains. The leaves were collected and dried, extracted for essential oil and ethanolic and hexan extracts were prepared. The yield of essential oil was measured and the chemical composition of the essential oil was determined using Gas Chromatography. The yield of essential oil was 1.3 ml/100 g, and the richest component was alpha-pinene. Our results showed that the ethanolic and hexan extracts of Myrtus communis had higher antibacterial activity against Gram positive bacteria (Staphylococcus aureus and Streptococcus pyogenes) than Gram negative bacteria (Escherichia coli and Pseudomonas aeruginosa). The ethanolic extract showed the greatest inhibitory effect against Staphylococcus aureus. These results demonstrate that Myrtus communis leaves extract has high antibacterial activity, making it a source of compounds to be used for the treatment of Gram-positive bacterial infections.","PeriodicalId":93114,"journal":{"name":"Journal of clinical research and reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43243307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric Caustic Ingestion: A Review Article","authors":"V. Erikçi","doi":"10.31579/2690-1919/248","DOIUrl":"https://doi.org/10.31579/2690-1919/248","url":null,"abstract":"Caustic ingestion injuries represent a significant morbidity and even mortality producing aerodigestive tract burns. Regarded as a major public health issue, caustic injuries may be produced by various chemicals including alkali and acid agents, phenols and oxidizing substances such as peroxides or chlorine bleaches. Public awareness including preventive measures is important in avoiding these injuries. The consequences of caustic ingestion may pose great challenge for both the patients, their families together with clinicians dealing with these children. In this review article it is aimed to discuss the clinical presentations, treatment modalities of these children under the light of relevant literature.","PeriodicalId":93114,"journal":{"name":"Journal of clinical research and reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43846799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}