HSOA journal of toxicology : current research最新文献

Dermal Irritation Study of Pankajakasthuri Orthoherb Cream/Thermagel, a Potent Polyherbal Anti-inflammatory and Analgesic Formulation for Topical Application in Healthy New Zealand White Rabbits Pankajakashuri正草药乳膏/Thermagel的皮肤刺激性研究，这是一种用于健康新西兰白兔局部应用的强效多草药抗炎镇痛制剂

HSOA journal of toxicology : current research Pub Date : 2021-10-04 DOI: 10.24966/tcr-3735/100022

Sasidharan S

引用次数: 0

Perspective: Considerations for Prevention and Treatment of Dermal Exposure to Toxic Organophosphorus Compounds 观点:皮肤接触有毒有机磷化合物的预防和治疗的考虑

HSOA journal of toxicology : current research Pub Date : 2021-10-04 DOI: 10.24966/tcr-3735/100021

M. Ehrich

引用次数: 0

Ameliorating Effect Of Emblica Officinalis On Lipid Profile Of Endosulfan Induced Mice 甘油三酯对硫丹诱导小鼠血脂的改善作用

HSOA journal of toxicology : current research Pub Date : 2020-09-02 DOI: 10.24966/TCR-3735/100020

S. Jha

引用次数: 0

Occupational Exposure Of Formaldehyde At Some Mortuaries In The Ashanti Region Of Ghana 加纳阿散蒂地区一些停尸房的职业性甲醛暴露

HSOA journal of toxicology : current research Pub Date : 2020-06-17 DOI: 10.24966/tcr-3735/100014

Asare-Donkor Nk

{"title":"Occupational Exposure Of Formaldehyde At Some Mortuaries In The Ashanti Region Of Ghana","authors":"Asare-Donkor Nk","doi":"10.24966/tcr-3735/100014","DOIUrl":"https://doi.org/10.24966/tcr-3735/100014","url":null,"abstract":"Formaldehyde is the main ingredient in embalming liquids used in mortuaries for preserving bodies. Due to its carcinogenicity, it has raised questions about the occupational health of workers in health facilities that work with formaldehyde. This poses health risk to morticians, hospital workers and mortuary workers. This study measures the formaldehyde levels both indoor and outdoor at some selected mortuaries in the Ashanti region of Ghana. Air samples were taken from various rooms, corridors and immediate environment of these mortuaries using the 3-methyl-2-benzothiazolinone hydrazine hydrochloride method. Temperature and relative humidity were also measured and a survey on the potential formaldehyde sources in these facilities and health effects were administered to respondents at the same time. The levels of formaldehyde recorded for mortuaries in this study ranged between 14-710μg/m3. Temperature and relative humidity were positively correlated with the level of formaldehyde (p=0.003). Workers in the mortuaries complained of symptoms such as eye irritation, nose and throat irritations, headaches and sometimes vomiting. These symptoms are related to specific place of activity within the facility and how frequent a particular worker visits or comes to work weekly. The hazard quotient values calculated ranged from 0.1 to 5.2.","PeriodicalId":93103,"journal":{"name":"HSOA journal of toxicology : current research","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89880317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Microplastics And Bisphenol A (BPA) In Sediments Of Coastal Lagoons Of Veracruz, Mexico 墨西哥韦拉克鲁斯海岸泻湖沉积物中的微塑料和双酚A (BPA)

HSOA journal of toxicology : current research Pub Date : 2020-06-17 DOI: 10.24966/tcr-3735/100015

Botello Av

引用次数: 0

Diurnal Gain And Nocturnal Reduction Of Body Weight In Young Adult Rabbits: The Reverse Of The Circadian Rhythm Observed In Rats And Mice 幼兔日增夜减体重:在大鼠和小鼠中观察到的昼夜节律逆转

HSOA journal of toxicology : current research Pub Date : 2020-06-17 DOI: 10.24966/tcr-3735/100016

S. Kawamura

{"title":"Diurnal Gain And Nocturnal Reduction Of Body Weight In Young Adult Rabbits: The Reverse Of The Circadian Rhythm Observed In Rats And Mice","authors":"S. Kawamura","doi":"10.24966/tcr-3735/100016","DOIUrl":"https://doi.org/10.24966/tcr-3735/100016","url":null,"abstract":"Citation: Kawamura S, Yamazoe H, Hosokawa Y (2020) Diurnal Gain and Nocturnal Reduction of Body Weight in Young Adult Rabbits: The Reverse of the Circadian Rhythm Observed in Rats and Mice. J Toxicol Cur Res 4: 016. Abstract Understanding circadian rhythms in experimental animals is im-portant to comprehensively evaluate animal responses to chemical exposure and gain deep insight into the pharmacological and toxico- logical effects of chemical exposure. Animals may respond different-ly to chemical exposure at different time points because many bodily functions have daily rhythms. In rats and mice, major experimental animals used in toxicology studies, circadian changes in physi- ological parameters including body weight, food consumption and hormones have been reported. In rabbits, the other principal experimental animal in teratology, circadian rhythms of behavioural functions such as physical activity and food intake, but not body weight change, have been described. To better understand fundamental biological characteristics of rabbits, we measured body weight and food consumption of male and female rabbits of two strains in the morning and evening for several days, calculating diurnal and nocturnal body weight changes and food intake per hour during the interval. Rabbits as well as rats and mice ate more at night than during the day. Nevertheless, rabbits showed diurnal increase and nocturnal decrease of body weight. This is the reverse of the circadian change observed in rats and mice. There was no strain-specific difference in the circadian rhythms in body weight and food consumption in rabbits. Male and female rabbits showed a similar daily rhythm in body weight and food consumption. In conclusion, there was a remark-able species difference in circadian rhythm in body weight between rats and rabbits.","PeriodicalId":93103,"journal":{"name":"HSOA journal of toxicology : current research","volume":"51 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75740758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Morphology-dependent titanium dioxide nanoparticle-induced keratinocyte toxicity and exacerbation of allergic contact dermatitis. 形态依赖的二氧化钛纳米颗粒诱导的角质细胞毒性和过敏性接触性皮炎的恶化。

HSOA journal of toxicology : current research Pub Date : 2020-01-01 Epub Date: 2020-06-17 DOI: 10.24966/tcr-3735/100019

Brian C Palmer, Lisa A DeLouise

引用次数: 0

Prolonged Exposure To Ultrafine Black Carbon (UBC) In Combination With Microbial Proxies Trigger Oxidative, Proliferative, And Innate Immune Perturbations In Pulmonary Lung-Derived Cells 长时间暴露于超细黑碳(UBC)和微生物代用物会引发肺源性细胞的氧化、增殖和先天免疫扰动

HSOA journal of toxicology : current research Pub Date : 2019-12-20 DOI: 10.24966/tcr-3735/100013

Salinas M Esther

引用次数: 0

Envenomings Caused By Venomous Animals In Roraima: A Neglected Health Problem In The Brazil’s Northernmost State 在罗赖马由有毒动物引起的中毒:在巴西最北部的州被忽视的健康问题

HSOA journal of toxicology : current research Pub Date : 2019-12-20 DOI: 10.24966/tcr-3735/100011

Wállex Matias Pedroso Souza

{"title":"Envenomings Caused By Venomous Animals In Roraima: A Neglected Health Problem In The Brazil’s Northernmost State","authors":"Wállex Matias Pedroso Souza","doi":"10.24966/tcr-3735/100011","DOIUrl":"https://doi.org/10.24966/tcr-3735/100011","url":null,"abstract":"A Neglected Health Abstract Accidents caused by venomous animals are an important global neglected disease with high impact in Brazilian Amazon. The sub- stantial numbers of envenomings registered in the Amazon region can be explained by the optimal conditions for the venomous fauna ( e.g climate), however, the numbers are underestimated owing to extensive under-reporting. This study carried out an epidemiological study of envenomings caused by venomous animals in the state of Roraima, the Brazil’s Northernmost state within a typical vegetation of Amazon rainforest. Envenomings by venomous animals between 2013 and 2016 were collected from 15 municipalities of Roraima and statistically analyzed using different parameters. Data were collected from the National Notifiable Diseases Information System (SINAN). During the studied period, Roraima presented 2,239 envenomings within venomous animals, with most of them registered in the capital Boa Vista. In addition, male victims between 20 and 39-years old prevailed. Regarding the length of time between the accident and therapy ( i.e antivenom administration), 72.7% of the victims were treated in less than 6 hours. Fortunately, most of the Roraima en- venomings were classified as mild, with exception to snakebites, in which victims were associated to present moderate envenomings, although deaths were considered rare. The high incidence of en- venomings caused by venomous animals in Roraima, as well as the induced-moderate severity in victims of snakebites,contribute to the knowledge of the local reality, which is needed to advocate mea sures that aim to reduce the accidents by venomous animal attacks and promote therapeutic measures, such as supplying of specific antivenoms in places where they are most required.","PeriodicalId":93103,"journal":{"name":"HSOA journal of toxicology : current research","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86875054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

In-Vitro Investigation of the Cytotoxic and Genotoxic Effects of Benzimidazole Group Pesticides Benomyl and Carbendazim 苯并咪唑类农药苯甲酰和多菌灵的细胞毒性和基因毒性体外研究

HSOA journal of toxicology : current research Pub Date : 2019-08-07 DOI: 10.24966/tcr-3735/100007

M. Kara

引用次数: 1