E. Mattos, I. Guimaraes, Alexander Gonçalves da Silva, Claudia Marcia Borges Barreto, G. Teixeira
{"title":"Smart Device Clickers","authors":"E. Mattos, I. Guimaraes, Alexander Gonçalves da Silva, Claudia Marcia Borges Barreto, G. Teixeira","doi":"10.4018/978-1-5225-8903-7.ch066","DOIUrl":"https://doi.org/10.4018/978-1-5225-8903-7.ch066","url":null,"abstract":"In the traditional instructional paradigm, faculty members act like actors on a stage. They memorize their speech and deliver it to the audience, many times with very little to no interaction at all with the audience. On the other hand, in the student-centered learning paradigm, faculty members act like coaches interacting full time with their team. This chapter is based on a study conducted at a Brazilian Federal University. The study depicts the distance between science production and teaching, and reports on experiences using smart phone clickers to track and analyze students' content acquisition. The objective is to improve the interactive quality of teaching and learning, thus promoting steps to shift towards a student-centered instructional paradigm. Although smartphones were used in this study, with wearable technologies continuing to grow, other wearables such as smart glasses and smart watches could be used instead.","PeriodicalId":93084,"journal":{"name":"Biotechnology (Faisalabad, Pakistan)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70435326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intelligent Biomedical Engineering Operations by Cloud Computing Technologies","authors":"Hasan Armutlu","doi":"10.4018/978-1-5225-4769-3.CH015","DOIUrl":"https://doi.org/10.4018/978-1-5225-4769-3.CH015","url":null,"abstract":"Cloud computing is an effective way of using hardware- and software-oriented resources at optimum levels. Thanks to this technology, it is possible to share large amounts of resources effectively and accurately among target users. Because it is a rapidly growing technology, one cannot deny that it has remarkable relations with alternative research fields having great potential and application scope. It is clear that artificial intelligence is one of these fields. As associated with both these research fields, the purpose of this chapter is to examine artificial-intelligence-based biomedical engineering works supported/connected with cloud computing. Because it has a vital importance with applications regarding the medical/health problems, biomedical engineering needs support from the most recent technologies and research fields in this manner. So, the chapter provides a view over the intersection of these three research fields as trying to improve awareness among interested readers.","PeriodicalId":93084,"journal":{"name":"Biotechnology (Faisalabad, Pakistan)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70434182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enzyme Function Classification","authors":"M. M. Sharif, A. Tharwat, A. Hassanien, H. Hefny","doi":"10.4018/978-1-5225-8903-7.ch015","DOIUrl":"https://doi.org/10.4018/978-1-5225-8903-7.ch015","url":null,"abstract":"Enzymes are important in our life and it plays a vital role in the most biological processes in the living organisms and such as metabolic pathways. The classification of enzyme functionality from a sequence, structure data or the extracted features remains a challenging task. Traditional experiments consume more time, efforts, and cost. On the other hand, an automated classification of the enzymes saves efforts, money and time. The aim of this chapter is to cover and reviews the different approaches, which developed and conducted to classify and predict the functions of the enzyme proteins in addition to the new trends and challenges that could be considered now and in the future. The chapter addresses the main three approaches which are used in the classification the function of enzymatic proteins and illustrated the mechanism, pros, cons, and examples for each one.","PeriodicalId":93084,"journal":{"name":"Biotechnology (Faisalabad, Pakistan)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70434532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Paratexts and Documentary Practices","authors":"Nicholas M. Weber, A. Thomer","doi":"10.4018/978-1-5225-8903-7.ch024","DOIUrl":"https://doi.org/10.4018/978-1-5225-8903-7.ch024","url":null,"abstract":"The formal literature of science has traditionally acted as a “ledger” where debts are acknowledged, previous works are cited, and advances in knowledge are claimed. Recent innovation in electronic publishing, as well as open access requirements from funding agencies in the life sciences, is making it possible to examine this ledger more closely: we can now more definitively ask who is acknowledged, where do citations appear, and what knowledge is claimed within an entire discipline, journal or archive of publications. In this chapter, the authors explore the ledger of bioinformatics, asking how two paratexts—acknowledgment and authorship statements—can be used to understand credit and collaboration within this unique field.","PeriodicalId":93084,"journal":{"name":"Biotechnology (Faisalabad, Pakistan)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70434585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Industrial Enzyme Technology","authors":"M. Osho","doi":"10.4018/978-1-5225-8903-7.ch055","DOIUrl":"https://doi.org/10.4018/978-1-5225-8903-7.ch055","url":null,"abstract":"Biotechnology, being the application of biological organisms and their components in pharmaceutical and other industrial processes, has emerged as the basic transformation tool for starch hydrolysis enzyme. Several advantages over chemical catalysts under mild environmental conditions with efficiency and high specificity have been accrued to this fact. Such include ingredient substitution through continuous fermentation, increased products yield and plant capacity, processing aid substitution, more efficient processing, less undesirable products with improved products. This chapter reports on the molecular properties of thermostable enzymes such as alpha-amylases, alpha-glucosidases, glucoamylases pullulanases as relates to pharmaceutical industries; highlights various technology development, continuous solid-state fermentation, metabolic engineering, sol-gel immobilized enzyme arrays often use in enzyme industries. The new modern biotechnology leads to improvement in the effects of various physiological conditions which may allow various industrial processes to carry out lower energy consumption, harmless to the environment, high efficiency, and the product's properties enhancement.","PeriodicalId":93084,"journal":{"name":"Biotechnology (Faisalabad, Pakistan)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70434987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Open Access Journal in Bioinformatics","authors":"Rekha Pareek, Sudhir Kumar","doi":"10.4018/978-1-5225-8903-7.ch063","DOIUrl":"https://doi.org/10.4018/978-1-5225-8903-7.ch063","url":null,"abstract":"Bioinformatics is rapidly growing, interdisciplinary field of science, where methods from information technology, computer science, mathematics, and statistics are used to solve problems of biological science. To access latest scholarly articles in such an important branch one cannot deny the importance of open access journals. In this chapter an attempt has been made to access the current status of open access journals of bioinformatics which are covered by Directory of Open Access Journals (DOAJ) on various parameters like country and language of publication, their currency, impact factor, article processing charges, copyright licensing model they are using, platform for hosting and their coverage in abstracting/indexing databases.","PeriodicalId":93084,"journal":{"name":"Biotechnology (Faisalabad, Pakistan)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70435034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cancer Biomarker Assessment Using Evolutionary Rough Multi-Objective Optimization Algorithm","authors":"Anasua Sarkar, U. Maulik","doi":"10.4018/978-1-4666-7258-1.CH016","DOIUrl":"https://doi.org/10.4018/978-1-4666-7258-1.CH016","url":null,"abstract":"A hybrid unsupervised learning algorithm, which is termed as Evolutionary Rough Multi-Objective Optimization (ERMOO) algorithm, is proposed in this chapter. It comprises a judicious integration of the principles of the rough sets theory with the archived multi-objective simulated annealing approach. While the concept of boundary approximations of rough sets in this implementation deals with the incompleteness in the dynamic classification method with the quality of classification coefficient as the classificatory competence measurement, it enables faster convergence of the Pareto-archived evolution strategy. It incorporates both the rough set-based dynamic archive classification method in this algorithm. A measure of the amount of domination between two solutions is incorporated in this chapter to determine the acceptance probability of a new solution with an improvement in the spread of the non-dominated solutions in the Pareto-front by adopting rough sets theory. The performance is demonstrated on real-life breast cancer dataset for identification of Cancer Associated Fibroblasts (CAFs) within the tumor stroma, and the identified biomarkers are reported. Moreover, biological significance tests are carried out for the obtained markers.","PeriodicalId":93084,"journal":{"name":"Biotechnology (Faisalabad, Pakistan)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4018/978-1-4666-7258-1.CH016","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70428513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hriday Kumar, V. Chandramohan, Smrithy M. Simon, R. Yadav, Sunil Kumar
{"title":"Big Data Analysis Techniques for Visualization of Genomics in Medicinal Plants","authors":"Hriday Kumar, V. Chandramohan, Smrithy M. Simon, R. Yadav, Sunil Kumar","doi":"10.4018/978-1-5225-3142-5.CH026","DOIUrl":"https://doi.org/10.4018/978-1-5225-3142-5.CH026","url":null,"abstract":"In this chapter, the complete overview and application of Big Data analysis in the field of health care industries, Clinical Informatics, Personalized Medicine and Bioinformatics is provided. The major tools and databases used for the Big Data analysis are discussed in this chapter. The development of sequencing machines has led to the fast and effective ways of generating DNA, RNA, Whole Genome data, Transcriptomics data, etc. available in our hands in just a matter of hours. The complete Next Generation Sequencing (NGS) huge data analysis work flow for the medicinal plants are discussed in the chapter. This chapter serves as an introduction to the big data analysis in Next Generation Sequencing and concludes with a summary of the topics of the remaining chapters of this book.","PeriodicalId":93084,"journal":{"name":"Biotechnology (Faisalabad, Pakistan)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70433172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is China Catching Up?","authors":"P. Hanel","doi":"10.4018/978-1-5225-8903-7.ch071","DOIUrl":"https://doi.org/10.4018/978-1-5225-8903-7.ch071","url":null,"abstract":"The chapter examines whether Chinese health-related biotechnology is catching up with leaders in the field. The approach is inspired by Malerba's Sectoral System of Innovation and Production, complemented by Mathew's insight into strategies for latecomer firms. The results show that Chinese scientists are quickly catching up in the output of scientific publications. However, the basic research remains insufficient for the development of a sustainable, innovative industry. The industrial production of biotechnology-based manufacturing of drugs and medical devices is growing slower than their knowledge base. Most firms still manufacture under license or contract low-value “me too” generic pharmaceutical and biosimilar ingredients medicines. The intensity of R&D and patenting in China increased dramatically, especially in the foreign-invested firms but China's share of biotechnology patenting in the US, EPO and Japan are very low. In summary, Chinese biotechnology ‘industry' is catching up with the West, but it has a long way to go.","PeriodicalId":93084,"journal":{"name":"Biotechnology (Faisalabad, Pakistan)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70435018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Laccase Catalysis","authors":"Helina Patel, A. Gupte","doi":"10.4018/978-1-5225-8903-7.ch084","DOIUrl":"https://doi.org/10.4018/978-1-5225-8903-7.ch084","url":null,"abstract":"The search for cost-effective and environmental benign practices for the production of bioactive compounds has gained considerable attention since last decade, due to increasing demand of eco-friendly processes. Many industries have started adopting routes for the development of green chemistry by employing enzymatic approaches to overcome the limitations of physico-chemical methods and environmental concerns. Laccase is one such enzyme which has gained considerable attention in recent years as a biocatalyst in organic synthesis. Laccases possess versatile biochemical properties and the reactions catalyzed by laccase require only molecular oxygen with concomitant release of water as a byproduct. They have been widely used for reactions such as dimerization, polymerization, coupling, and grafting reactions and for antibiotic modifications. This chapter summarizes the advances that have been made in developing technologies based on laccase mediated reactions in the field of medicine, agriculture, food, and pharmaceuticals.","PeriodicalId":93084,"journal":{"name":"Biotechnology (Faisalabad, Pakistan)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70435360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}