Bioscientifica proceedings最新文献_第7页

The metabolism of the ruminant cumulus-oocyte complex revisited 反刍动物卵丘-卵母细胞复合体的代谢

Bioscientifica proceedings Pub Date : 2019-04-05 DOI: 10.1530/BIOSCIPROCS.8.022

Jeremy G. Thompson, R. Gilchrist, M. Sutton-Mcdowall

引用次数: 3

Novel concepts about normal sexual differentiation of reproductive neuroendocrine function and the developmental origins of female reproductive dysfunction: the sheep model 关于生殖神经内分泌功能正常性分化和女性生殖功能障碍发育起源的新概念：绵羊模型

Bioscientifica proceedings Pub Date : 2019-04-05 DOI: 10.1530/BIOSCIPROCS.6.006

D. Foster, L. Jackson, V. Padmanabhan

引用次数: 0

What research is needed to improve commercial pig reproduction 需要进行哪些研究来改善商品猪繁殖

Bioscientifica proceedings Pub Date : 2019-04-05 DOI: 10.1530/biosciprocs.19.0038

S. Einarsson

{"title":"What research is needed to improve commercial pig reproduction","authors":"S. Einarsson","doi":"10.1530/biosciprocs.19.0038","DOIUrl":"https://doi.org/10.1530/biosciprocs.19.0038","url":null,"abstract":"Artificial insemination with fresh or stored semen is currently the only sperm technology used at a commercial scale in the pig industry. Attention should therefore be given for further improvement of the functionality and fertilizing ability of cryopreserved semen, as well as for sperm sorting for gender pre-selection. During the last two decades various proteins and polypeptides have been identified in boar seminal plasma, and the relevance of some of them to reproductive technologies has been discussed at this conference. The long- term goal should be to isolate/synthetize those seminal plasma proteins proven important for the spermatozoa, and use them as ingredients in media used for e.g. cryopreservation and sex sorting of semen. A close cooperation between biochemists, molecular biologists and animal scientists is necessary to reach this goal. The brought transcriptional profiling, allowing for the identification of many genes involved e.g. in mammalian gametogenesis, fertilization, and preimplantation embryo development. We do expect further progress within this field of research during coming years. The new information has also capacity to revolutionize the genetic progress within animal breeding. when using single insemination with fresh semen at fixed-time ovulation. deep with lower number, or inseminated","PeriodicalId":93083,"journal":{"name":"Bioscientifica proceedings","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45793591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Judge, jury and executioner: the auto-regulation of luteal function 法官、陪审团和刽子手:黄体功能的自动调节

Bioscientifica proceedings Pub Date : 2019-04-05 DOI: 10.1530/BIOSCIPROCS.6.012

G. Niswender, T. Davis, Griffith Rj, R. L. Bogan, K. Monser, Rebecca C. Bott, J. Bruemmer, Terry M. Nett

引用次数: 42

Next Generation Sequencing for microRNA profiling in the porcine endometrium 猪子宫内膜microRNA分析的下一代测序

Bioscientifica proceedings Pub Date : 2019-04-05 DOI: 10.1530/biosciprocs.19.0019

K. Krawczynski, S. Bauersachs, H. Blum, M. Kaczmarek

引用次数: 0

Developmental programming of the ovine placenta 绵羊胎盘发育程序

Bioscientifica proceedings Pub Date : 2019-04-05 DOI: 10.1530/BIOSCIPROCS.7.004

A. Fowden, J. Ward, F. Wooding, A. Forhead

引用次数: 0

Cryopreservation of female germplasm in pigs 猪母系种质的低温保存

Bioscientifica proceedings Pub Date : 2019-04-05 DOI: 10.1530/biosciprocs.19.0004

S. Tamas, K. Kikuchi, H. Kaneko, J. Noguchi, K. Yoshioka, T. Nagai

引用次数: 3

Pigs as model systems for biomedical research 猪作为生物医学研究的模型系统

Bioscientifica proceedings Pub Date : 2019-04-05 DOI: 10.1530/biosciprocs.19.0029

H. Niemann

{"title":"Pigs as model systems for biomedical research","authors":"H. Niemann","doi":"10.1530/biosciprocs.19.0029","DOIUrl":"https://doi.org/10.1530/biosciprocs.19.0029","url":null,"abstract":"Pigs have a long standing and very successful history as biomedical model for studying human diseases and developing novel therapies mainly attributed to the many genetic, anatomical and physiological similarities with humans. Non-transgenic pig models have long been used for a wide range of human organ systems and diseases, and even complex metabolic disorders and have served as model for developing novel surgical techniques and endoscopic approaches, such as NOTES (natural orifice transluminal endoscopic surgery). The availability of the porcine genome and novel tools to add or delete specific genes significantly expands the potential for transgenic pig production. Somatic cell nuclear transfer has emerged as the preferred method for transgenesis. Well characterized transgenic pig models have been reported for Cystic fibrosis, the eye disease Retinitis Pigmentosa, atherosclerosis and diabetes. Transgenic pigs have been produced for modeling neurological diseases, including Alzheimer and Huntington disease, specific forms of cancer, and skin diseases. Transgenic pigs play an important role in developing functional porcine xenografts to combat the growing shortage of appropriate human organs for transplantation. Other important transgenic pig models include immunodeficient pigs and Oct4/GFP transgenic pigs for studies of reprogramming. Pig models will not replace the already existing mouse models but can provide significant novel insight into a variety of diseases, as mouse models frequently do not mimic the human situation. Transgenic pigs will also soon play an increasing role in the development of novel therapies based on stem cell technology. The biomedical use of pigs will also facilitate transgenic pig production for agricultural production.","PeriodicalId":93083,"journal":{"name":"Bioscientifica proceedings","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48164358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Control of ovarian follicular development to the gonadotrophin-dependent phase: a 2006 perspective 控制卵泡发育到促性腺激素依赖阶段:2006年的观点

Bioscientifica proceedings Pub Date : 2019-04-05 DOI: 10.1530/BIOSCIPROCS.6.004

K. McNatty, P. Smith, D. Heath, Il Juengel

引用次数: 2

Steroidogenesis and the initiation of parturition 甾体形成和分娩的开始

Bioscientifica proceedings Pub Date : 2019-04-05 DOI: 10.1530/BIOSCIPROCS.8.028

A. Conley, L. Reynolds

{"title":"Steroidogenesis and the initiation of parturition","authors":"A. Conley, L. Reynolds","doi":"10.1530/BIOSCIPROCS.8.028","DOIUrl":"https://doi.org/10.1530/BIOSCIPROCS.8.028","url":null,"abstract":"One of the most fundamental axioms of mammalian reproduction is that pregnancy requires the support of progesterone without which it cannot be established or maintained. Though this basic physiological tenet was accepted long ago, major gaps in our understanding of the physiology of both pregnancy and parturition remain which hamper our ability to solve clinically and agriculturally significant problems such as low fertility, fetal growth restriction, preterm birth and poor neonatal outcomes. The historical reliance of our understanding of both pregnancy and parturition on this single hormone, and how it has been measured in the vast majority of studies, may represent a tangible weakness and impediment to progress. Other weaknesses include a desire to fit all species into a unified paradigm, and a reluctance to accept that physiological processes regulated by progesterone or other progestins in different tissues might vary in reliance on classic (nuclear receptor) versus other, non-classical mechanisms of action. The relative importance of these distinct response pathways in certain cells or tissues also may differ across species, as does so much of basic reproductive physiology. It is well known that certain species are reliant on luteal function throughout gestation, whereas the placenta subsumes endocrine support in others (Geisert & Conley 1998), yet progesterone alone is still believed to be the single common element. As radical as it might seem, however, progesterone may not be the single common hormone of pregnancy in mammals.","PeriodicalId":93083,"journal":{"name":"Bioscientifica proceedings","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41582090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6