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HSOA journal of stem cells research, development & therapy最新文献

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Short Review on Immune Response to Allogeneic Equine Mesenchymal Stromal Cells 马同种异体间充质间质细胞免疫应答研究综述
HSOA journal of stem cells research, development & therapy Pub Date : 2023-09-22 DOI: 10.24966/srdt-2060/100104
J Lacy Kamm
{"title":"Short Review on Immune Response to Allogeneic Equine Mesenchymal Stromal Cells","authors":"J Lacy Kamm","doi":"10.24966/srdt-2060/100104","DOIUrl":"https://doi.org/10.24966/srdt-2060/100104","url":null,"abstract":"Our research investigated the interaction of the cell-mediated and innate arms of the immune system with allogeneic Mesenchymal Stromal Cells (MSCs). This study monitored population changes and activation of Equine Leukocyte Antigen (ELA) - mismatched leukocytes in direct co-culture with MSCs. Cytotoxic T cells, helper T cells, regulatory T cells, B cells and neutrophils were identified using flow cytometry","PeriodicalId":93004,"journal":{"name":"HSOA journal of stem cells research, development & therapy","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136100396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of Membrane-Like Pre-Stem Cells after Released from Tube-Shaped Niches 从管状壁龛释放后膜样前干细胞的发育
HSOA journal of stem cells research, development & therapy Pub Date : 2023-09-22 DOI: 10.24966/srdt-2060/100107
Wuyi Kong, XiuJuan Han, XiaoPing Zhu, Hong Wang
{"title":"Development of Membrane-Like Pre-Stem Cells after Released from Tube-Shaped Niches","authors":"Wuyi Kong, XiuJuan Han, XiaoPing Zhu, Hong Wang","doi":"10.24966/srdt-2060/100107","DOIUrl":"https://doi.org/10.24966/srdt-2060/100107","url":null,"abstract":"We previously identified three distinct pre-stem cell lineages that further develop into blood CD34-positive stem cells, and mesenchymal stem cells. The pre-CD34-positive stem cells are spore-like, while the pre-mesenchymal stem cells are fusiform-shaped. All of them originate or released from tube-shaped tissue structures, or niches. In the current study, we present two membrane-like pre-stem progenitors","PeriodicalId":93004,"journal":{"name":"HSOA journal of stem cells research, development & therapy","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136100234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Experience of Thymic Regeneration with Thymus Extracts, Thymic Peptides and Stem Cells in General Medicine, Oncology and Anti-Aging Medicine: A Review 胸腺提取物、胸腺肽和干细胞在普通医学、肿瘤学和抗衰老医学中胸腺再生的临床经验
HSOA journal of stem cells research, development & therapy Pub Date : 2023-09-22 DOI: 10.24966/srdt-2060/100106
Mike KS Chan, Michelle BF Wong, Thomas Skutella, Roni Moya, Dmytro Klokol
{"title":"Clinical Experience of Thymic Regeneration with Thymus Extracts, Thymic Peptides and Stem Cells in General Medicine, Oncology and Anti-Aging Medicine: A Review","authors":"Mike KS Chan, Michelle BF Wong, Thomas Skutella, Roni Moya, Dmytro Klokol","doi":"10.24966/srdt-2060/100106","DOIUrl":"https://doi.org/10.24966/srdt-2060/100106","url":null,"abstract":"Thymus plays a crucial role in immune system development and T-cell maturation. With aging, thymus activity declines, which leads to a weakened immune system and an increased risk of infections and cancer. In recent years, thymus extract has gained attention as a potential treatment for cancer and anti-aging. Studies have suggested that thymus extract can stimulate the production of T-cells and enhance immune function, which may lead to improved outcomes in cancer patients","PeriodicalId":93004,"journal":{"name":"HSOA journal of stem cells research, development & therapy","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136100399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Autologous stem cell transplantation in Primary Central Nervous System Lymphoma: A Systematic Review 自体干细胞移植治疗原发性中枢神经系统淋巴瘤:系统综述
HSOA journal of stem cells research, development & therapy Pub Date : 2023-09-22 DOI: 10.24966/srdt-2060/100105
Sara Steffanoni
{"title":"Autologous stem cell transplantation in Primary Central Nervous System Lymphoma: A Systematic Review","authors":"Sara Steffanoni","doi":"10.24966/srdt-2060/100105","DOIUrl":"https://doi.org/10.24966/srdt-2060/100105","url":null,"abstract":"Consolidation therapy demonstrated to improve the outcome of naïve patients affected by Primary Central Nervous System Lymphoma (PCNSL). In the past, Whole Brain Radiotherapy (WBRT) represented the standard consolidation approach for PCNSL in response after high dose methotrexate-based induction chemotherapy","PeriodicalId":93004,"journal":{"name":"HSOA journal of stem cells research, development & therapy","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136100225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extracellular Matrix Scaffolds - A Tissue-Specific Bioactive Niche for Stem Cells in Regenerative Therapy 细胞外基质支架-干细胞再生治疗中的组织特异性生物活性生态位
HSOA journal of stem cells research, development & therapy Pub Date : 2021-12-31 DOI: 10.24966/srdt-2060/100086
Yehonatan Zur, Tzila Davidov, L. Baruch, M. Machluf
{"title":"Extracellular Matrix Scaffolds - A Tissue-Specific Bioactive Niche for Stem Cells in Regenerative Therapy","authors":"Yehonatan Zur, Tzila Davidov, L. Baruch, M. Machluf","doi":"10.24966/srdt-2060/100086","DOIUrl":"https://doi.org/10.24966/srdt-2060/100086","url":null,"abstract":"Aiming to restore the normal function of diseased or injured tissues, regenerative therapy approaches are generally based on the engineering of complex tissue-mimicking grafts, encompassing biomaterial scaffolds, stem cells, or their combinations [1-4]. Due to the major role of stem cells in physiological regenerative mechanisms, regenerative therapies normally rely on either stem cells transplantation or stem cell recruitment from the neighboring tissue into the implanted scaffold","PeriodicalId":93004,"journal":{"name":"HSOA journal of stem cells research, development & therapy","volume":"145 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73238622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Regenerative Therapy for Sensorineural Hearing Loss: Recent Progress and Future Directions 感觉神经性听力损失的再生治疗:最新进展和未来方向
HSOA journal of stem cells research, development & therapy Pub Date : 2021-12-31 DOI: 10.24966/srdt-2060/100082
J. Baumgartner, Linda S. Baumgartner
{"title":"Regenerative Therapy for Sensorineural Hearing Loss: Recent Progress and Future Directions","authors":"J. Baumgartner, Linda S. Baumgartner","doi":"10.24966/srdt-2060/100082","DOIUrl":"https://doi.org/10.24966/srdt-2060/100082","url":null,"abstract":"Sensorineural Hearing Loss (SNHL) continues to be a significant public health problem with over 270 million affected people worldwide and an incidence that increases with age [1,2]. Some cases of SNHL have a genetic cause, but the majority of SHNL is the result of ototoxic insult [3]","PeriodicalId":93004,"journal":{"name":"HSOA journal of stem cells research, development & therapy","volume":"28 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72469812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Upper Full Rehabilitation with One to One Immediate Loading Implants: A Case Report 单对单即刻装填种植体上颌全康复一例报告
HSOA journal of stem cells research, development & therapy Pub Date : 2021-12-31 DOI: 10.24966/srdt-2060/100084
M. Serafini, Sara Di Teodoro, Luisa Romondio, L. Zagaria
{"title":"Upper Full Rehabilitation with One to One Immediate Loading Implants: A Case Report","authors":"M. Serafini, Sara Di Teodoro, Luisa Romondio, L. Zagaria","doi":"10.24966/srdt-2060/100084","DOIUrl":"https://doi.org/10.24966/srdt-2060/100084","url":null,"abstract":"The purpose of this clinical case report is to describe a full-arch rehabilitation with one to one endosseous implant restoration. Although the proposed treatment may not be within the financial means of most patients, the aesthetical result is higher because of the close similarity between the final restorations and the natural dentition.","PeriodicalId":93004,"journal":{"name":"HSOA journal of stem cells research, development & therapy","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73839362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Introducing New Neurons in the Alzheimer’s Disease Brain 在阿尔茨海默病的大脑中引入新的神经元
HSOA journal of stem cells research, development & therapy Pub Date : 2021-12-31 DOI: 10.24966/srdt-2060/100080
Castro A. Gonzalez
{"title":"Introducing New Neurons in the Alzheimer’s Disease Brain","authors":"Castro A. Gonzalez","doi":"10.24966/srdt-2060/100080","DOIUrl":"https://doi.org/10.24966/srdt-2060/100080","url":null,"abstract":"Alzheimer’s disease is the most prevalent neurodegenerative disorder in the elderly population. The patients suffer cerebral atrophyas a consequence of extensive neuronal loss, especially in areas that play a role in memory and cognition. Cell therapies approaches have emerged as promising treatments to regenerate the brain tissue of the patients","PeriodicalId":93004,"journal":{"name":"HSOA journal of stem cells research, development & therapy","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75618201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microgravity Significantly Influences Neural Stem Cells Size and Numbers: Implications for Long-term Space Missions 微重力显著影响神经干细胞的大小和数量:对长期太空任务的影响
HSOA journal of stem cells research, development & therapy Pub Date : 2021-12-31 DOI: 10.24966/srdt-2060/100088
Sophia Shaka, Nicolas Carpo, Victoria Tran, Carlos Cepeda, A. Espinosa‐Jeffrey
{"title":"Microgravity Significantly Influences Neural Stem Cells Size and Numbers: Implications for Long-term Space Missions","authors":"Sophia Shaka, Nicolas Carpo, Victoria Tran, Carlos Cepeda, A. Espinosa‐Jeffrey","doi":"10.24966/srdt-2060/100088","DOIUrl":"https://doi.org/10.24966/srdt-2060/100088","url":null,"abstract":"There are two approaches used to study the effects of microgravity on cells -- using simulated microgravity on Earth (sim-µG) or sending cells to space (SPC-µG). We have recently reported that human neural stem cells (NSCs) proliferated seven-times more while in space than Ground Control (GC) NSCs on Earth. Here, using time-lapse microscopy, we determined that in both sim-µG and SPC-µG there are two cell subpopulations distinguished by differences in somatic diameter","PeriodicalId":93004,"journal":{"name":"HSOA journal of stem cells research, development & therapy","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85947052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Mesenchymal Stem Cell-Based Treatment of Osteoarthritis in Dogs - A Review 间充质干细胞治疗犬骨关节炎的研究进展
HSOA journal of stem cells research, development & therapy Pub Date : 2021-12-31 DOI: 10.24966/srdt-2060/100083
M. Domaniža, A. Trbolová, M. Hluchý, D. Čížková
{"title":"Mesenchymal Stem Cell-Based Treatment of Osteoarthritis in Dogs - A Review","authors":"M. Domaniža, A. Trbolová, M. Hluchý, D. Čížková","doi":"10.24966/srdt-2060/100083","DOIUrl":"https://doi.org/10.24966/srdt-2060/100083","url":null,"abstract":"Osteoarthritis (OA) is Degenerative Joint Disease (DJD) associated with pain, inflammation and cartilage degradation resulting in lameness. This state is irreversible and actual conventional therapies are not able to provide regeneration of damaged tissue. Current therapies, mainly NSAIDs, have many adverse effects and are not able to stop degenerative process","PeriodicalId":93004,"journal":{"name":"HSOA journal of stem cells research, development & therapy","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75213941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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