微重力显著影响神经干细胞的大小和数量:对长期太空任务的影响

Sophia Shaka, Nicolas Carpo, Victoria Tran, Carlos Cepeda, A. Espinosa‐Jeffrey
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引用次数: 2

摘要

有两种方法用于研究微重力对细胞的影响——在地球上模拟微重力(sim-µG)或将细胞送入太空(SPC-µG)。我们最近报道了人类神经干细胞(NSCs)在太空中的增殖能力是地球上地面控制(GC) NSCs的7倍。在这里,使用延时显微镜,我们确定在sim-µG和SPC-µG中都有两个细胞亚群,通过体细胞直径的差异来区分
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Microgravity Significantly Influences Neural Stem Cells Size and Numbers: Implications for Long-term Space Missions
There are two approaches used to study the effects of microgravity on cells -- using simulated microgravity on Earth (sim-µG) or sending cells to space (SPC-µG). We have recently reported that human neural stem cells (NSCs) proliferated seven-times more while in space than Ground Control (GC) NSCs on Earth. Here, using time-lapse microscopy, we determined that in both sim-µG and SPC-µG there are two cell subpopulations distinguished by differences in somatic diameter
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