Indian journal of cardiovascular disease in women WINCARS最新文献

{"title":"Hyponatremia in Acute Decompensated Heart Failure as a Predictor of Acute Cardiorenal Syndrome Type-1","authors":"","doi":"10.25259/ijcdw_27_2022","DOIUrl":"https://doi.org/10.25259/ijcdw_27_2022","url":null,"abstract":"\u0000\u0000Acute cardiorenal syndrome (CRS type-1) refers to an acute worsening of heart function, leading to acute kidney injury (AKI), frequently complicating acute decompensated heart failure (ADHF). This study aims to investigate whether hyponatremia, is a surrogate marker for the development of AKI in patients admitted with ADHF.\u0000\u0000\u0000\u0000Sample size – 100 patients with ADHF. Age – More than 18 years. Investigations – 2D-ECHO, N-terminal pro-brain natriuretic peptide, kidney function test, estimated glomerular filtration rate, USG abdomen, complete blood picture, chest X-ray, and complete urine examination.\u0000\u0000\u0000\u0000On analysis of data, 63.5% (n=33) of patients who had hyponatremia (n=45) eventually developed AKI during hospital stay, whereas 36.5% (n=19) of patients who did not have hyponatremia (n=36) developed AKI. Hyponatremia was found to be a statistically significant (P = 0.001) predictor of increased incidence of AKI in a predetermined group of patients with HF in our study, and ADHF patients with hyponatremia have a 5.21-fold higher risk of developing AKI (95% CI, 2.20–12.36) than ADHF patients without hyponatremia.\u0000\u0000\u0000\u0000Hyponatremia predicts complications while admission in heart failure patients like type-I CRS and it has also been shown that comorbidities could play an important role in the presence or absence of hyponatremia and could even influence the length of hospital stay attributed to lower serum sodium levels which need further clinical trials.\u0000","PeriodicalId":92905,"journal":{"name":"Indian journal of cardiovascular disease in women WINCARS","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87511847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Female Gender and COVID-19 Aftermath: Audacious Times Ahead?","authors":"P. Kapoor","doi":"10.25259/ijcdw_31_2023","DOIUrl":"https://doi.org/10.25259/ijcdw_31_2023","url":null,"abstract":"","PeriodicalId":92905,"journal":{"name":"Indian journal of cardiovascular disease in women WINCARS","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82757817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bending Saturation Index – A Novel Index of Old Symptom a Marker of Elevated Filling Pressure in Heart Failure","authors":"Purushotham Reddy","doi":"10.25259/ijcdw_5_2023","DOIUrl":"https://doi.org/10.25259/ijcdw_5_2023","url":null,"abstract":"\u0000\u0000Bendopnea is a symptom in patients with heart failure (HF) defined as shortness of breath when bending forward. It is mediated by increased ventricular filling pressure during bending forward. Qualification of bendopnea and its correltion with other symptoms and parameters of HF is not a much explored area. In this study, we studied the frequency of bendopnea in patients admitted with HF and a index of difference between sitting and bending saturations and its correlation with clinical, laboratory, and echocardiographic and short-term mortality.\u0000\u0000\u0000\u0000We conducted a study of 150 patients admitted with DHF in the span of 5 month and followed for 1 month. Bendopnea is defined as subjective sensation of worsening shortness of breath after bending for 1 min or more. Saturations after bending for 1 min are also recorded for each patient. Bendopnea saturation index (BOSI) is calculated as difference between saturations at baseline and after bending over, its percentage over baseline saturation (SaO2 sitting - SaO2 bending/SaO2 sitting*100).\u0000\u0000\u0000\u0000It was present in 61 patients (40.7%). Among 150 patients, 11 patientns (7.3%) expired. Orthopnea was more frequent in patients with bendopnea compared to patients without (59% of patients with bendopnea also had orthopnea and 34.8% of patients without bendopnea had orthopnea, and the difference was statistically significant (P = 0.03). Paroxysmal nocturnal dyspnea (PND) was present in 29.5% of patients with bendopnea and 11% of patients without bendopnea (P = 0.05). The patients with bendopnea had higher right ventricular systolic pressure (RVSP) (49.9 ± 1.6) compared to patients without bendopnea (33.5 ± 0.9). Average NT pro BNP values were 8717 ± 950 pg/mL in patients with bendopnea and 1110 ± 99 pg/mL in patients without bendopnea (P < 0.005). Mean BOSI was 4.4 (±2.9) in patients with bendopnea and 0.4 (±0.09) in patients without bendopnea. There was a negative correlation between BOSI and left ventricular ejection fraction (LVEF), and positive correlation between BOSI and RVSP. Among patients with bendopnea, six patients expired, when compared with patients who were alive after 1 month using t-test, patients who expired have higher average BOSI (P < 0.005).\u0000\u0000\u0000\u0000Bendopnea and falling of desaturation on bending is a sign of significance in HF patients. The presence of bendopnea correlated with increased pulmonary arterial pressure and with other symptoms of respiratory variation, namely – orthopnea and PND, and higher values of biomarker (NTproBNP). BOSI, but not bendopnea had significant positive correlation with RVSP, and negative correlation with LVEF. BOSI also correlated with short-term mortality.\u0000","PeriodicalId":92905,"journal":{"name":"Indian journal of cardiovascular disease in women WINCARS","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73730517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Post Myocardial Infarction – Heart Failure Recurrence and Outcomes, Does Gender Play an Important Role?","authors":"","doi":"10.25259/ijcdw_23_2023","DOIUrl":"https://doi.org/10.25259/ijcdw_23_2023","url":null,"abstract":"","PeriodicalId":92905,"journal":{"name":"Indian journal of cardiovascular disease in women WINCARS","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86795289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances in Intravascular Ultrasound","authors":"Archana Remala, Kapil Karthikeya Reddy, P. Velagapudi","doi":"10.25259/ijcdw_2_2023","DOIUrl":"https://doi.org/10.25259/ijcdw_2_2023","url":null,"abstract":"Since its inception, intravascular ultrasound (IVUS) and optical coherence tomography (OCT) have played a significant role in evaluating the pathophysiology of coronary artery disease (CAD) guiding the interventional and medical management of CAD improving outcomes in patients. Although the benefits of each of these modalities have been proven, due to some limitations, no single intravascular imaging technique has been proven to provide a detailed and complete evaluation of all CAD lesions. The use of different intravascular imaging modalities sequentially may lead to complications, which are cumbersome, consume time, and add financial burden to the patient. Recently, hybrid imaging catheters that combine OCT and IVUS benefits have been developed to limit these problems. Intravascular imaging techniques we are using currently have some drawbacks that hinder accurate assessment of plaque morphology and pathobiology as demonstrated in many histological studies, causing difficulty in identifying high-risk plaques. To overcome these limitations, great efforts have been put into developing hybrid, dual-probe catheters by combining imaging modalities to get an accurate analysis of plaque characteristics, and high-risk lesions. At present, many dual-probe catheters are available including combined IVUS-OCT, near-infrared spectroscopy-IVUS that is available commercially, the OCT-near infrared fluorescence (NIRF) molecular imaging, IVUS-NIRF, and combined fluorescence lifetime-IVUS imaging. Application of this combined multimodal imaging in clinical practice overcomes the limitations of standalone imaging and helps in providing a comprehensive and accurate visualization of plaque characteristics, composition, and plaque biology. The present article summarizes the advances in hybrid intravascular imaging, analyses the technical hindrances that should be known to have a use in the different clinical circumstances, and the till date shreds of evidence available from their first clinical application aiming to bring these modalities into the limelight and their potential role in the study of CAD.","PeriodicalId":92905,"journal":{"name":"Indian journal of cardiovascular disease in women WINCARS","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78388530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epicardial Fat Tissue Thickness as a Cardiovascular Risk Marker and its Association with Microalbuminuria in Patients with Essential Hypertension","authors":"C. Kashyap, Hemanth Harish","doi":"10.25259/ijcdw_24_2022","DOIUrl":"https://doi.org/10.25259/ijcdw_24_2022","url":null,"abstract":"\u0000\u0000Hypertension is one of the essential modifiable risk factors in causing stroke, renal disease, cardiovascular diseases, and peripheral artery disease. Epicardial fat tissue is regarded as endocrine organ and is metabolically active as it produces angiotensinogen and free fatty acids which are proinflammatory cytokines and are atherogenic. The presence of microalbuminuria has been associated with endothelial dysfunction that predisposes to cardiovascular events. The aim of this study is to determine the association of epicardial fat tissue with age, sex, serum creatinine, left ventricular (LV) mass, serum albumin, low-density lipoprotein (LDL), and triglycerides in patients with essential hypertension.\u0000\u0000\u0000\u0000One hundred patients with essential hypertension were divided into two groups each having 50 patients. Group A included urinary albumin creatinine ratio (UACR) <30 mg/g. Group B included UACR >30 mg/g. Age, body mass index, blood pressure, creatinine, urea, albumin, LDL, triglycerides, and epicardial adipose tissue thickness (EAT) were evaluated and compared between two groups. All patients underwent UACR, transthoracic echocardiography to determine EAT, LV mass, and ejection fraction.\u0000\u0000\u0000\u0000In our study, EAT ranged from 2 mm to 6.9 mm, with mean value of 3.21 mm and 5.12 mm in Groups A and B, respectively. Mean EAT values were found to be higher in Group B compared to A and was found to be statistically significant. Similarly, LDL, triglycerides, serum albumin levels, and LV mass showed significant difference among two groups. Serum albumin level in Group B was significantly reduced than the patients with normal urine albumin creatinine ratio.\u0000\u0000\u0000\u0000EAT serve as an important indicator in patients with essential hypertension to determine target organ damage and to stratify high risk group.\u0000","PeriodicalId":92905,"journal":{"name":"Indian journal of cardiovascular disease in women WINCARS","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79628411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of In-stent Restenosis","authors":"S. Chhabra, J. Majella","doi":"10.25259/ijcdw_25_2023","DOIUrl":"https://doi.org/10.25259/ijcdw_25_2023","url":null,"abstract":"Despite recent improvements in percutaneous coronary intervention (PCI), in-stent restenosis (ISR) — which accounts for 5–10% of all PCI procedures in contemporary clinical practice remains a substantial problem and the most frequent reason for stent failure. While the absolute number of ISR-PCI operations performed in contemporary practice has increased as a result of rising procedural volume and complexity, the relative rate of ISR has decreased with newer-generation drug eluting stents (DESs) in comparison to the bare metal stent (BMS) period. While BMS ISR is usually early and characterized by neointimal hyperplasia, DES ISR tends to be late with neoatherosclerosis as a characteristic feature. According to recent research, drug-coated balloons or DESs are the most effective therapy options for the majority of ISR cases. Future ISR interventional paradigms may be influenced by intravascular imaging (IVI) ISR tissue patterns. IVI can provide useful information to guide treatment options in ISR-PCI.","PeriodicalId":92905,"journal":{"name":"Indian journal of cardiovascular disease in women WINCARS","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85600470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of Post-catheterization Femoral Artery Pseudoaneurysm","authors":"S. Rajashekhar, Achukatla Kumar","doi":"10.25259/ijcdw_24_2023","DOIUrl":"https://doi.org/10.25259/ijcdw_24_2023","url":null,"abstract":"\u0000\u0000To compare the affected patients with the age- and sex-matched patients in the control group.\u0000\u0000\u0000\u0000All patients who had undergone PCI, left heart catheterization, or coronary angiography between July and November 2022 were prospectively recruited. We included 247 patients in our study who underwent cardiac catheterization via femoral access.\u0000\u0000\u0000\u0000The incidence of FAP after a diagnostic catheterization was 5.97% and 8.69% after an interventional procedure. The mean age of the patients with FAP was 54.06 ± 15.04 years and 62.5% patients were females in the affected group. In FAP group, 14 patients (87.5%) had hypertension, 8 patients (50%) had diabetes, and 37.5% were had obesity. The systolic blood pressure was 145.38 ± 29.99 mmHg, while the diastolic blood pressure was 86 ± 14.59 mmHg. Data obtained from computed tomography scanning showed that the arterial wall of the CFA was healthy in 11 patients (68.5%), while diffuse atherosclerosis was detected in 5 (31.5%) patients. In 69% of the patients, FAPs were connected to the CFA and in 31% patients to the superficial femoral artery (SFA). In 38% (6) patients partial thrombosis of the pseudoaneurysm sac observed.\u0000\u0000\u0000\u0000FAP is a common vascular complication after a diagnostic procedure or percutaneous cardiac catheterization, and its prevalence is likely to rise.\u0000","PeriodicalId":92905,"journal":{"name":"Indian journal of cardiovascular disease in women WINCARS","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84743371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complications of PCI and its Management","authors":"A. Mahilmaran","doi":"10.25259/ijcdw_20_2023","DOIUrl":"https://doi.org/10.25259/ijcdw_20_2023","url":null,"abstract":"Contemporary percutaneous coronary intervention (PCI) has few complications and enhanced safety on one hand and on the other hand, available modern tools have enabled interventional cardiologists to venture into more complex patient subsets and fresh challenges in tackling the ensuing newer complications. Individual operators may take several years of experience before being exposed to the complications and hence, it is important to learn from the collective experience on the detection and management of these complications and better equipped to handle them when the need arises. The complications of PCI can be access related or coronary intervention related. The common acute coronary complications include abrupt vessel closure, thrombus, slow flow, dissection, perforation, stent dislodgement, and guidewire fracture and embolization. The chronic complications include late stent thrombosis, in-stent restenosis, and aneurysm formation. The use of imaging, physiology, and plaque modification tools are associated with specific complications which need to be kept in mind while using them. The successful management of complications needs prompt recognition, involving help from others and continued team effort and vigilance.","PeriodicalId":92905,"journal":{"name":"Indian journal of cardiovascular disease in women WINCARS","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88528088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of Aortic Root Movement with Left Ventricular Function","authors":"Imran Shaik","doi":"10.25259/ijcdw_25_2022","DOIUrl":"https://doi.org/10.25259/ijcdw_25_2022","url":null,"abstract":"\u0000\u0000The motion of structures of the heart is the basis for cardiac function. Factors such as low image quality and low signal-to-noise ratio create hindrances in the adequate valuation of left ventricular (LV) systolic and diastolic function. Even in cases with poor image quality, the aorta being a large structure is well visualized. One of the unorthodox approaches to the assessment of heart function is the study of aortic root movement.\u0000\u0000\u0000\u0000We studied patients who came to the Nizam Institute of Medical Sciences. The ethics committee of the institute approved our study. We studied 85 patients who came to the emergency or outpatient department with or without various cardiovascular problems. We have included patients who presented with myocardial infarction, arrhythmia, and heart failure, cerebrovascular accident. We measured the constants pertaining to the aortic root motion and LV function with the standard parameters of echocardiography. Then, we aimed to check for a correlation between aortic root movement parameters and the LV function of the heart. Patients filling the inclusion criteria were enrolled in the study after taking informed consent. The data from the participants were collected prospectively. We recorded the echocardiography according to the standard guidelines. We used the Vivid E9 scanner (GE Vingmed Ultrasound AS) with the M5S-D (1.7–3.3 MHz) cardiac probe to acquire the data. We studied the echocardiographic 2D images and Doppler parameters. We used the parasternal long axis view as well as the parasternal short axis view to measure the aortic movement.\u0000\u0000\u0000\u0000We included a total number of 85 patients as per the defined criteria among which 22 (25.88%) are females and 63 (74.11%) are males. The average age of enrolled participants was 56.30 years (±14.95 years). The mean age of the patients was 56.3 ± 14.9. About 75% of the subjects had LV dysfunction and the remaining had normal lv function. Sixty-five patients had LV dysfunction either due to ischemic or non-ischemic cardiomyopathy. We, then, checked for the relationship between the aortic root constants and the LV function parameters. We found the mean value of aortic root diastolic distance (ARDD) as 2.59 ± 0.43 cm and. The aortic root maximal diastolic velocity (ARDV) was 10.8 ± 2.4 cm/s. The aortic root systolic distance (ARSD) was 2.71 ± 0.65 cm. The aortic root maximal systolic velocity (ARSV) was 7.92 ± 2.26 cm/s. Mean aortic root excursion was 4.3 mm. Aortic root systolic excursion (ARSE) showed a parallel relation with LV function (r up to 0.7). We found ARSD and ARSV correlating weakly with systolic Doppler parameters, such as ejection fraction (EF), maximum annular plane systolic excursion (MAPSE), and s' medial. ARSE was an exception that it showed a good correlation with s’medial r = 0.746 (P < 0.001), EF r = 0.807 (P < 0.001), and MAPSE r = 0.68 (P < 0.001). The ARDD and ARDV related poorly with LV diastolic parameters such as e' mean, e' medial, e' lateral, E/A, an","PeriodicalId":92905,"journal":{"name":"Indian journal of cardiovascular disease in women WINCARS","volume":"64 2-3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78454402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}