Calabar journal of health sciences最新文献

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Utilization of obstetric ultrasonography and findings in a cottage hospital in Nigeria 尼日利亚一家乡村医院产科超声检查的应用和结果
Calabar journal of health sciences Pub Date : 2021-10-19 DOI: 10.25259/cjhs_25_2021
G. Inah, A. I. Ngaji, A. Erim, Ofonime N. Ukweh, A. Fajola, Jo Gagar
{"title":"Utilization of obstetric ultrasonography and findings in a cottage hospital in Nigeria","authors":"G. Inah, A. I. Ngaji, A. Erim, Ofonime N. Ukweh, A. Fajola, Jo Gagar","doi":"10.25259/cjhs_25_2021","DOIUrl":"https://doi.org/10.25259/cjhs_25_2021","url":null,"abstract":"\u0000\u0000The integration of ultrasound into routine obstetric workup has transformed antenatal care in resource-poor and remote communities in Africa. The present study aims to investigate the utilization of obstetric ultrasound at a cottage hospital in suburban Nigeria.\u0000\u0000\u0000\u0000This retrospective study was conducted at Obio Cottage Hospital, Port Harcourt, Rivers State, South-South Nigeria. Ethical approval was obtained before commencement of the study from the Health Research Ethics Committee of University of Calabar Teaching Hospital with reference number UCTH/HREC/33/533. Reports were retrieved from the records of the radiology unit of the study facility, and data including biometric data and radiological diagnosis were transferred to Microsoft Excel spreadsheet for data analysis. Simple proportions and percentages were used to analyze the data. All statistical analyses were conducted using Statistical Package for the Social Science version 21.0, IBM Inc., Chicago, Illinois, USA. Statistical significance was set at P ≤ 0.05.\u0000\u0000\u0000\u0000The total ANC visits at Obio Cottage Hospital was 28,072, with 27% (7689) utilization of ultrasound scan. The mean age and range of parity of attendees were 32 ± 2.3 and 1–5, respectively. Of the total scans performed, 99.93% was routine, while 0.07% (5) was clinical-based (targeted). Normal findings were 7520 (97.8%) of antenatal scans recorded, while abnormal cases, multiple gestation, and uncertain diagnosis accounted for 121 (1.57%), 44 (0.57%), and 4 (0.06%), respectively.\u0000\u0000\u0000\u0000The present study has shown a considerable volume of obstetric ultrasound scan in this cottage hospital, albeit, with low utilization compared to the number of antenatal registration. Findings were mainly normal with minimal need for referral for advance care.\u0000","PeriodicalId":92883,"journal":{"name":"Calabar journal of health sciences","volume":"100 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75672573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HIV serodiscordant and nondisclosure rates among married women living with HIV in a Southern Nigerian region 尼日利亚南部地区感染艾滋病毒的已婚妇女的艾滋病毒血清不一致性和不披露率
Calabar journal of health sciences Pub Date : 2021-10-19 DOI: 10.25259/cjhs_2_2021
U. Akpan, K. Arogundade, Ezukwa Omoronyia, A. Udo, M. Ekott, S. Etuk
{"title":"HIV serodiscordant and nondisclosure rates among married women living with HIV in a Southern Nigerian region","authors":"U. Akpan, K. Arogundade, Ezukwa Omoronyia, A. Udo, M. Ekott, S. Etuk","doi":"10.25259/cjhs_2_2021","DOIUrl":"https://doi.org/10.25259/cjhs_2_2021","url":null,"abstract":"\u0000\u0000Intimate sexual partners’ disclosure of HIV positive status is vital in the control of HIV/AIDS pandemic globally. The disclosure rates vary from region to region. The aim of this study was to document the prevalence of HIV serodiscordance and partners disclosure rate; and also determine the associated factors among HIV positive married women living in Calabar region of Nigeria.\u0000\u0000\u0000\u0000A cross-sectional survey was conducted among 260 married women, 18 years and above, receiving HIV care at various health institutions in the region. Data were analyzed using SPSS VERSION 23. Their demographic and health profile were presented in simple proportion and percentages while Chi-square test and logistic regression were used to determine the factors influencing patient’s HIV status disclosure with the level of significance set at 0.05.\u0000\u0000\u0000\u0000A total of 254 compiled questionnaires were included in the analysis (response rate-97.7%). The serodiscordant rate was 50%. HIV status disclosure to partner was high, 89.4%. The main determinants of HIV status disclosure were good level of education (AOR = 2.2, 95% CI: = 1.75–2.53, P = 0.007) and long duration of ART use (AOR = 3.23, 95% CI = 2.78–4.15, P = 0.001) while women with high discordant rate were more likely to be divorced/separated (P = 0.012, OR = 1.67).\u0000\u0000\u0000\u0000Female education is an important factor in HIV control. Disclosure of HIV status is beneficial to the partner as it promotes safe sex practices and increases adherence to ART.\u0000","PeriodicalId":92883,"journal":{"name":"Calabar journal of health sciences","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83844508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diastolic versus systolic dysfunction in patients with chronic liver disease – A single center study in South-South, Nigeria 慢性肝病患者的舒张与收缩功能障碍——尼日利亚南南的单中心研究
Calabar journal of health sciences Pub Date : 2021-06-30 DOI: 10.25259/cjhs_5_2021
U. Njideofor, U. Okonkwo, V. Ansa, C. Odigwe
{"title":"Diastolic versus systolic dysfunction in patients with chronic liver disease – A single center study in South-South, Nigeria","authors":"U. Njideofor, U. Okonkwo, V. Ansa, C. Odigwe","doi":"10.25259/cjhs_5_2021","DOIUrl":"https://doi.org/10.25259/cjhs_5_2021","url":null,"abstract":"\u0000\u0000The term cirrhotic cardiomyopathy (CCM) has been used to describe the constellation of cardiovascular abnormalities including diastolic and systolic dysfunctions in patients with chronic liver disease (CLD). CCM contributes to morbidity and mortality associated with CLD. The aim of the study was to evaluate the left atrial and ventricular geometry, systolic and diastolic functions in patients with CLD.\u0000\u0000\u0000\u0000This was a cross-sectional analytical study that involved 80 patients with CLD seen at University of Calabar Teaching Hospital, Calabar, Nigeria, and 80 apparently healthy controls matched for age/ gender. The participants were interviewed, examined and had resting transthoracic echocardiography. The data were analyzed using IBM SPSS version 20.0.\u0000\u0000\u0000\u0000A total of 160 subjects were recruited into the study with a male to female ratio of 2.8:1. There was no difference in the mean age of cases and controls (P = 0.115). Systolic function of the left ventricle was similar in the two arms. However, left ventricular diastolic dysfunction, left atrial enlargement, and increased left ventricular mass index (LVMI) were more prevalent among the patients with CLD compared to controls (P < 0.05).\u0000\u0000\u0000\u0000The study demonstrated increased left atrial diameter, increased LVMI associated with diastolic dysfunction, and preserved systolic function at rest among CLD patients.\u0000","PeriodicalId":92883,"journal":{"name":"Calabar journal of health sciences","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89110744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Awareness and satisfaction with antenatal care services among pregnant women in Lagos state, Nigeria 尼日利亚拉各斯州孕妇对产前保健服务的认识和满意度
Calabar journal of health sciences Pub Date : 2021-06-30 DOI: 10.25259/cjhs_53_2020
I. Ademuyiwa, R. Opeke, A. Farotimi, A. Ejidokun, A. O. Olowe, E. Ojo
{"title":"Awareness and satisfaction with antenatal care services among pregnant women in Lagos state, Nigeria","authors":"I. Ademuyiwa, R. Opeke, A. Farotimi, A. Ejidokun, A. O. Olowe, E. Ojo","doi":"10.25259/cjhs_53_2020","DOIUrl":"https://doi.org/10.25259/cjhs_53_2020","url":null,"abstract":"\u0000\u0000Despite the growing interest and efforts by government to make popular use of antenatal care (ANC) services in Nigeria as recommended by the World Health Organization, high level of infant and maternal mortality remains a major public health challenge facing the country. Dissatisfaction toward ANC services among pregnant women may be attributed to low level of awareness. This study assessed the level of awareness and satisfaction of ANC services among pregnant women in Lagos state, Nigeria.\u0000\u0000\u0000\u0000The study adopted a survey research design. A multistage sampling technique was utilized to recruit participants for this study. A validated questionnaire was used for data collection and data were analyzed using both descriptive and inferential statistics. Ethical approval was obtained from Babcock University Health Research Ethics Committee with approval no: BUHREC543/17. Approval was also obtained from health service commission and in the six general hospitals used for the study. Informed consent was taken and respondents were reassured of the privacy and confidentiality of the information obtained.\u0000\u0000\u0000\u0000The results showed that most of the respondents (85.6%) were in their reproductive years, that is, ages 23–37. The results showed that the level of awareness had a significant influence on pregnant women’s satisfaction with the services (β = 0.460, F(1,1313) = 351.499, R2 = 0.211, P < 0.05). The level of awareness of ANC services was high (M = 4.31, SD = 1.01) on a scale of 5.\u0000\u0000\u0000\u0000The study concluded that awareness of ANC services positively impacts pregnant women’s satisfaction with the services in Lagos state. Efforts should be made to improve the level of awareness of pregnant mothers to achieve greater satisfaction with ANC services in Lagos state.\u0000","PeriodicalId":92883,"journal":{"name":"Calabar journal of health sciences","volume":"514 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80095594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contact corneal thermal burn from domestic electric clothes iron in a female teenager: A case report 家用电熨斗致女青少年接触性角膜热烧伤1例报告
Calabar journal of health sciences Pub Date : 2021-06-30 DOI: 10.25259/cjhs_14_2021
E. Ezeh, R. Ezeh
{"title":"Contact corneal thermal burn from domestic electric clothes iron in a female teenager: A case report","authors":"E. Ezeh, R. Ezeh","doi":"10.25259/cjhs_14_2021","DOIUrl":"https://doi.org/10.25259/cjhs_14_2021","url":null,"abstract":"Corneal thermal burn from domestic electric clothes pressing iron is a very rare occurrence among teenagers in Nigeria. We report the case of thermal burn to the ocular surface of a 16-year-old female, at home, from the sole plate of an electric clothes pressing iron. She presented with superficial eyelids and corneal burns (Roper-Hall Classification Grade II; Dua Classification Grade II). The patient was successfully managed with topical cyclopentolate 2%, topical moxifloxacin 0.5%, and tetracycline ointment. Well-documented causative agents of domestic eye injuries in the young in Nigeria are usually flying missiles. Thermal ocular injuries are quite uncommon, and when they occur, are likely due to steam burns. This report highlights the electric clothes pressing iron as a domestic hazard that caregivers must be mindful of.","PeriodicalId":92883,"journal":{"name":"Calabar journal of health sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84057765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Rectovaginal fistula: An early complication of radiotherapy in a sexagenarian with cervical cancer 直肠阴道瘘:放疗的早期并发症在六十多岁宫颈癌
Calabar journal of health sciences Pub Date : 2021-06-30 DOI: 10.25259/cjhs_18_2021
S. Efanga, A. Akintomide, Sandra Nwamaka Okekemba, Rekpene Bassey Ezeume
{"title":"Rectovaginal fistula: An early complication of radiotherapy in a sexagenarian with cervical cancer","authors":"S. Efanga, A. Akintomide, Sandra Nwamaka Okekemba, Rekpene Bassey Ezeume","doi":"10.25259/cjhs_18_2021","DOIUrl":"https://doi.org/10.25259/cjhs_18_2021","url":null,"abstract":"A 62-year-old Nigerian woman was admitted on account of cervical carcinoma Stage IV and was requested to undergo radiotherapy and chemotherapy. Six weeks after commencing this treatment she starting passing feces involuntarily through the vagina. Imaging studies revealed a high sited, medium sized, and rectovaginal fistula (RVF). RVFs have been documented as a late complication of radiotherapy for any gynecological malignancy but it occurred earlier in this patient. A preliminary surgical procedure, a sigmoid-ostomy, was performed successfully and a definitive surgery, a sigmoido-rectal anastomosis, was planned to be done in 18 months after the diagnosis of the RVF but the patient died shortly after the first procedure. The present case indicates that a RVF can occur as an early complication of radiotherapy even when it presents with mild symptoms.","PeriodicalId":92883,"journal":{"name":"Calabar journal of health sciences","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82724042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adjunctive orthodontic management of a missing upper right central incisor in a 12-year-old male using a fixed orthodontic appliance 使用固定正畸矫治器治疗12岁男性右上正中门牙缺失的辅助正畸治疗
Calabar journal of health sciences Pub Date : 2021-06-30 DOI: 10.25259/cjhs_39_2020
M. Adekoya
{"title":"Adjunctive orthodontic management of a missing upper right central incisor in a 12-year-old male using a fixed orthodontic appliance","authors":"M. Adekoya","doi":"10.25259/cjhs_39_2020","DOIUrl":"https://doi.org/10.25259/cjhs_39_2020","url":null,"abstract":"This article presents a successful orthodontic management of a 12-year-old male using a fixed orthodontic appliance (straight wire technique). His orthodontic treatment was hinged on creating enough space to accept an artificial tooth, correcting the horizontal and vertical relationships of the upper incisors to the lower and the midline shift. Ultimately, an esthetic smile was achieved; function and self-esteem were improved when the artificial tooth was finally fixed.","PeriodicalId":92883,"journal":{"name":"Calabar journal of health sciences","volume":"118 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76687577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient satisfaction with intraoral examination in a Nigerian tertiary hospital 尼日利亚某三级医院患者对口腔内检查的满意度
Calabar journal of health sciences Pub Date : 2021-06-30 DOI: 10.25259/cjhs_56_2020
E. Edetanlen, O. Babalola, Ufadime Lawani
{"title":"Patient satisfaction with intraoral examination in a Nigerian tertiary hospital","authors":"E. Edetanlen, O. Babalola, Ufadime Lawani","doi":"10.25259/cjhs_56_2020","DOIUrl":"https://doi.org/10.25259/cjhs_56_2020","url":null,"abstract":"\u0000\u0000While studies on satisfaction following medical procedures are well documented, but this is not so with dental procedures. Therefore, this study aims to determine the level of satisfaction in patient undergoing intraoral examination (IOE).\u0000\u0000\u0000\u0000Consecutive patients attending the oral diagnosis clinic of University of Benin Teaching Hospital from April 2020 to September 2020 were interviewed using a questionnaire modified from the modified Group Health Association of America-9 questionnaire.\u0000\u0000\u0000\u0000A total number of 103 consecutive dental patients were recruited as they all agreed to participate in the study. The age range was 18–77 years with a mean age of 35.8 ± 14.3 years. There were more males (51.5%). The overall satisfaction was 82.5%. The maximum satisfactory response was on doctor’s manner (93.2%), followed by staff ’s manner (89.3%), comfort during IOE (80.6%), adequate explanation (78.6%), and finally by waiting time (60.2%). There was association between occupation (P = 0.04) of the patients, type of dental condition (P = 0.03), waiting time (P = 0.01), doctor’s manner (P = 0.00), staff manner (P = 0.00), adequate explanation (P = 0.00), comfort during IOE (P = 0.00), and level of satisfaction. The problem rate was 16%.\u0000\u0000\u0000\u0000Although waiting time and adequate explanation ranked the highest in terms of unfavorable responses, the overall satisfaction of patients following IOE was generally good. The factors that influence satisfaction were occupation of the patients, type of dental condition, waiting time, doctor’s manner, staff manner, adequate explanation, and comfort during IOE.\u0000","PeriodicalId":92883,"journal":{"name":"Calabar journal of health sciences","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88365845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kawasaki disease; rare; or misdiagnosed: A case report in a tertiary hospital in Nigeria 川崎病;罕见的;或误诊:尼日利亚某三级医院一例报告
Calabar journal of health sciences Pub Date : 2021-06-30 DOI: 10.25259/cjhs_30_2020
C. Enyuma, Anthony Chimereze Amajor, E. Akpah, E. Brown-Abang
{"title":"Kawasaki disease; rare; or misdiagnosed: A case report in a tertiary hospital in Nigeria","authors":"C. Enyuma, Anthony Chimereze Amajor, E. Akpah, E. Brown-Abang","doi":"10.25259/cjhs_30_2020","DOIUrl":"https://doi.org/10.25259/cjhs_30_2020","url":null,"abstract":"Kawasaki disease (KD) is a self-limiting, acute febrile vasculitis with predilection for children under-5 years. Most reports have emanated from Japan with only a few cases reported in Africa. KD presents a diagnostic dilemma and a high index of suspicion is critical as early treatment reduces the incidence of complications. We describe a 5-month-old male infant who presented with classical clinical features though with delayed diagnosis. Received moderate dose aspirin with limitation of access to intravenous immunoglobulin and who did not develop coronary artery complication. The case report highlights the diagnostic challenges faced by practitioners, made worse by the low index of suspicion inherent in our setting. The fatal complications that may be associated with KD can, therefore, be avoided. It is hoped that pediatricians in particular would become conversant with the diagnostic criteria to facilitate early diagnosis and intervention in children.","PeriodicalId":92883,"journal":{"name":"Calabar journal of health sciences","volume":"90 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84525916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detection of antimalarial drug resistance polymorphisms in Plasmodium falciparum chloroquine resistance transporter and Plasmodium falciparum multidrug resistance 1 genes of Plasmodium falciparum found in Kano State, Nigeria 尼日利亚卡诺州恶性疟原虫氯喹耐药转运体和恶性疟原虫多重耐药基因1抗疟药多态性检测
Calabar journal of health sciences Pub Date : 2021-06-30 DOI: 10.25259/cjhs_14_2020
A. Adamu, O. Olonitola, H. Inabo, A. B. Suleiman
{"title":"Detection of antimalarial drug resistance polymorphisms in Plasmodium falciparum chloroquine resistance transporter and Plasmodium falciparum multidrug resistance 1 genes of Plasmodium falciparum found in Kano State, Nigeria","authors":"A. Adamu, O. Olonitola, H. Inabo, A. B. Suleiman","doi":"10.25259/cjhs_14_2020","DOIUrl":"https://doi.org/10.25259/cjhs_14_2020","url":null,"abstract":"\u0000\u0000In 2018, malaria claimed an estimated 380,000 lives in African region, with Nigeria accounting for 24.0% (91,368) of malaria deaths from the region. Mutations in Plasmodium falciparum chloroquine resistance transporter (Pfcrt) and P. falciparum multidrug resistance 1 (Pfmdr-1) genes had reduced the effective use of artemisinin combination therapy through the development of resistance to these antimalarial agents. Our study set out to determine the antimalarial drug resistance polymorphisms in Pfcrt and Pfmdr-1 genes of P. falciparum isolates among patients in Kano State, Nigeria.\u0000\u0000\u0000\u0000Malaria positive samples were collected across the three senatorial districts of Kano State. The samples were amplified using nested polymerase chain reaction to detect the Pfcrt and Pfmdr-1 genes. The amplicons were sequenced and bioinformatic analysis was done using CLC Sequence viewer 8.0 and BioEdit sequence alignment editor to detect the single-nucleotide polymorphisms.\u0000\u0000\u0000\u0000In the Pfcrt gene, CVIET haplotype was seen in 26.2% of the samples while only two samples showed the 86Y mutation in the Pfmdr-1 gene. All the 86Y mutations and majority of the CVIET haplotypes were detected in the patients from rural settings where some of them noted that they consumed modern and traditional (herbs) antimalarial agents. One sample was observed to have the CVIET haplotype and N86Y mutation while the other five CVIET haplotypes were seen in five separate samples. A new mutation V62A was found in the Pfmdr-1 gene as observed in one of the sample.\u0000\u0000\u0000\u0000It is imperative to ensure the rational use of the right antimalarial agents and employ continuous resistance surveillance/mapping to ensure synergy in malaria containment and elimination strategies.\u0000","PeriodicalId":92883,"journal":{"name":"Calabar journal of health sciences","volume":"64 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85052164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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