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Advances in antiviral drug design Pub Date : 2007-01-01 Epub Date: 2007-09-02 DOI: 10.1016/S1075-8593(06)05008-8
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引用次数: 0
Status Presens of Antiviral Drugs And Strategies: Part I: DNA Viruses and Retroviruses. 抗病毒药物和策略的现状:第一部分:DNA病毒和逆转录病毒。
Advances in antiviral drug design Pub Date : 2007-01-01 Epub Date: 2007-09-02 DOI: 10.1016/S1075-8593(06)05001-5
Erik De Clercq
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引用次数: 1
Status presens of antiviral drugs and strategies: Part II: RNA VIRUSES (EXCEPT RETROVIRUSES). 抗病毒药物和策略的现状:第二部分:RNA病毒(逆转录病毒除外)。
Advances in antiviral drug design Pub Date : 2007-01-01 Epub Date: 2007-09-02 DOI: 10.1016/S1075-8593(06)05002-7
Erik De Clercq
{"title":"Status presens of antiviral drugs and strategies: Part II: RNA VIRUSES (EXCEPT RETROVIRUSES).","authors":"Erik De Clercq","doi":"10.1016/S1075-8593(06)05002-7","DOIUrl":"https://doi.org/10.1016/S1075-8593(06)05002-7","url":null,"abstract":"<p><p>More than 40 compounds have been formally licensed for clinical use as antiviral drugs, and half of these are used for the treatment of HIV infections. The others have been approved for the therapy of herpesvirus (HSV, VZV, CMV), hepadnavirus (HBV), hepacivirus (HCV) and myxovirus (influenza, RSV) infections. New compounds are in clinical development or under preclinical evaluation, and, again, half of these are targeting HIV infections. Yet, quite a number of important viral pathogens (i.e. HPV, HCV, hemorrhagic fever viruses) remain in need of effective and/or improved antiviral therapies.</p>","PeriodicalId":92864,"journal":{"name":"Advances in antiviral drug design","volume":"5 ","pages":"59-112"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1075-8593(06)05002-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37833331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Methylenecyclopropane Analogues of Nucleosides as Anti-herpes Agents 核苷类亚甲基环丙烷类似物的抗疱疹作用
Advances in antiviral drug design Pub Date : 2007-01-01 DOI: 10.1016/S1075-8593(06)05003-9
J. Žemlička
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引用次数: 21
Synthesis and antiviral evaluation of broad spectrum, orally active analogs of cidofovir and other acyclic nucleoside phosphonates 西多福韦和其他无环核苷膦酸盐的广谱口服活性类似物的合成和抗病毒评价
Advances in antiviral drug design Pub Date : 2007-01-01 DOI: 10.1016/S1075-8593(06)05004-0
K. Hostetler
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引用次数: 8
The medicinal chemistry of the DATA and DAPY series of HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) DATA和DAPY系列HIV-1非核苷类逆转录酶抑制剂(NNRTIs)的药物化学研究
Advances in antiviral drug design Pub Date : 2007-01-01 DOI: 10.1016/S1075-8593(06)05006-4
J. Heeres, P. Lewi
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引用次数: 23
CCR5 antagonists for the treatment of HIV infection and AIDS CCR5拮抗剂治疗HIV感染和艾滋病
Advances in antiviral drug design Pub Date : 2007-01-01 DOI: 10.1016/S1075-8593(06)05005-2
M. Perros
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引用次数: 14
Inhibitors of human immunodeficiency virus integration 人类免疫缺陷病毒整合抑制剂
Advances in antiviral drug design Pub Date : 2003-01-01 DOI: 10.1016/S1075-8593(03)04002-4
D. Hazuda, S. D. Young
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引用次数: 10
Six-membered Carbocyclic Nucleosides 六元碳环核苷
Advances in antiviral drug design Pub Date : 2003-01-01 DOI: 10.1016/S1075-8593(03)04005-X
Jing Wang, M. Froeyen, P. Herdewijn
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引用次数: 5
cycloSal-Pronucleotides—Design of the Concept, Chemistry, and Antiviral Activity 环盐原核苷酸的概念设计、化学和抗病毒活性
Advances in antiviral drug design Pub Date : 2003-01-01 DOI: 10.1016/S1075-8593(03)04006-1
C. Meier
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引用次数: 11
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