Cooper Rowan medical journal最新文献

{"title":"Understanding Risk Perception and Xenophobic Attitudes during the Coronavirus Disease 2019 (COVID-19) Pandemic in the United States","authors":"Sera Yoo, W. Eger, A. Moore, Emily Miron, M. White","doi":"10.31986/issn.2578.3343_vol5iss1.6","DOIUrl":"https://doi.org/10.31986/issn.2578.3343_vol5iss1.6","url":null,"abstract":"Introduction: There have been over 87 million cases of Coronavirus Disease 2019 (COVID-19) in the United States (US).\u0000\u0000Objective: The objective of this study was to develop a novel questionnaire to assess risk perception of COVID-19 and xenophobic attitudes among adults in the US at the beginning of the pandemic.\u0000\u0000Methods: An anonymous self-report questionnaire was developed for this study in February 2020, and was distributed using convenience sampling from March 10 to March 25, 2020. The questionnaire assessed knowledge and risk perceptions of COVID-19, as well as attitudes toward individuals of various races and ethnicities.\u0000\u0000Results: 662 US adults completed the questionnaire. On a scale from 1 (low) to 5 (high), the mean risk perception was 3.44. Those with knowledge of COVID-19 and higher education levels reported higher risk perception and higher feelings of warmth towards Asian people. Forty percent of the sample had recently witnessed or experienced anti-Asian attitudes at the time of the survey. The majority of participants reported having heard about COVID-19 from news media, social media, and family or friends.\u0000\u0000Conclusions: Our sample had a moderate level of risk perception, potentially due to the time period of data collection (i.e., early in the pandemic course). The results suggest that knowledge about COVID-19 informed perceived risk and affected willingness to engage in healthy protective behaviors. Our study provides historic context of how people perceived the virus at the beginning of the pandemic, and gives insight into the aftermaths regarding quarantine and attitudes towards Asian Americans.","PeriodicalId":92771,"journal":{"name":"Cooper Rowan medical journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42492719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A tale of two situations: a case report of the merger between dermatology outcomes and prescription drug access","authors":"Kara Ye, Yasseen Amellal, Will Evans, T. Rohr-Kirchgraber","doi":"10.31986/issn.2578.3343_vol5iss1.5","DOIUrl":"https://doi.org/10.31986/issn.2578.3343_vol5iss1.5","url":null,"abstract":"This case report illustrates a case of guttate psoriasis in a young adult and the logistical role dermatologists can play in patients acquiring their prescriptions and improving the quality of their care.","PeriodicalId":92771,"journal":{"name":"Cooper Rowan medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46109508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of Knee Synovitis from Psoriatic Arthritis with Platelet Rich Plasma Injection","authors":"Nicolle Mazzei, Arielle Hall, Cody Clinton","doi":"10.31986/issn.2578.3343_vol5iss1.7","DOIUrl":"https://doi.org/10.31986/issn.2578.3343_vol5iss1.7","url":null,"abstract":"Psoriatic arthritis has been known to cause many inflammatory clinical features, including synovitis. In the past, synovitis has been primarily treated with NSAIDs, corticosteroid injections, and synovectomy when needed. This report outlines a 49-year-old female with synovitis caused by psoriatic arthritis who did not respond to conventional treatment options and was apprehensive to surgery. She was offered a platelet rich plasma (PRP) injection as alternative therapy to a synovectomy. This case explores the use of PRP injections as a potential treatment modality for patients with synovitis caused by psoriatic arthritis. This patient was able to show improvement in her symptoms after the use of the platelet rich plasma injection.","PeriodicalId":92771,"journal":{"name":"Cooper Rowan medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44957306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementation Barriers of Multidisciplinary Care in Chronic Kidney Disease Through a CFIR Framework: a Narrative Review","authors":"M. Goodman, Amalia Jereczek","doi":"10.31986/issn.2578.3343_vol5iss1.4","DOIUrl":"https://doi.org/10.31986/issn.2578.3343_vol5iss1.4","url":null,"abstract":"Introduction\u000037 million Americans suffer from chronic kidney disease, which affects multiple organ systems and requires multidisciplinary care. Multidisciplinary care is an inherently broad and complex topic, and while it is being implemented across health care in the United States and abroad, multidisciplinary care outcomes are poor in this patient population. It is possible that there exist gaps in the literature regarding implementation and replication of multidisciplinary care interventions such that health care practices are unable to fully take advantage of multidisciplinary care publications for chronic kidney disease. This narrative review utilizes the five domains of the Consolidated Framework for Implementation Research to address barriers to multidisciplinary care implementation for chronic kidney disease.\u0000Methods\u0000A systematized review of peer-reviewed literature including systematic reviews and meta-analyses related to chronic kidney disease and multidisciplinary care through January 1, 2021 was conducted. The five interventions with the most barriers qualitatively identified were analyzed.\u0000Results\u0000Twelve potentially eligible reviews were identified, and 5 unique systematic reviews and meta-analyses were selected for a total of 48 articles, and ultimately, 5 articles were selected for inclusion. Based on the Consolidated Framework for Implementation Research which includes 5 domains of barriers, we discussed barriers of implementation in all 5 domains within the 5 articles.\u0000Discussion\u0000Because it is essential that multidisciplinary care for patients with chronic kidney disease be improved and implemented to the fullest extent, researchers should be aware of barriers to implementation and publish results by taking into account the Consolidated Framework for Implementation Research.","PeriodicalId":92771,"journal":{"name":"Cooper Rowan medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44075287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding the Acceptability and Effect of Psychiatric Care via Telemedicine as an Alternative Option for Patients Living with Intellectual Disabilities in Group Homes","authors":"Brittany Johnson, Annabelle Rowland, Jacob D. Coeur, Maxwell C. Klapow","doi":"10.31986/issn.2578.3343_vol5iss1.3","DOIUrl":"https://doi.org/10.31986/issn.2578.3343_vol5iss1.3","url":null,"abstract":"Telemedicine has become a popular alternative to in-person clinic visits in the field of psychiatry, but few studies examine the impact of telemedicine mental healthcare provided to patients with intellectual disabilities living in group homes. Our study aims to fill this gap in the literature. A ten-question survey was designed to evaluate the effect of telemedicine services on access to care, quality of care, and patient and caregiver stress. This survey was distributed to caregivers of patients living in group homes who received care at the University of Alabama Medical Center. The majority of respondents indicated that telemedicine visits improved access to care, did not result in lower quality care compared to in-person visits, and adequately addressed the needs of the patient. Our findings suggest that telemedicine is an acceptable method of delivery of healthcare for a significant proportion of caregivers of patients surveyed.","PeriodicalId":92771,"journal":{"name":"Cooper Rowan medical journal","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135187000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long Term Neuroprotective Effects of Human Adipose-Derived Stem Cells in Neonatal Rats Post Hypoxic Ischemic Encephalopathy","authors":"Melissa February, Thomas N. Tulenko, Barry Weinberger, Alla Kushnir","doi":"10.31986/issn.2578.3343_vol5iss1.2","DOIUrl":"https://doi.org/10.31986/issn.2578.3343_vol5iss1.2","url":null,"abstract":"Background: Hypoxemic ischemic encephalopathy (HIE) is a major cause of morbidity and mortality in the neonatal population. Recent research has shown human adipose stem cells (hASCs) to have neuroprotective effects in animal models of HIE. This study tested the hypothesis that neurodevelopmental outcomes would be improved using hASC therapy in term neonatal HIE rat model.\u0000\u0000Methods: Seven day old rats underwent left carotid artery ligation followed by 8% oxygen for 120 minutes, or carotid isolation in shams. Forty-eight hours after surgery half of the rats received hASCs and half normal saline (NS) intravenously. Rota-rod and cylinder tests were used to assess skill learning, balance, coordination, and symmetry of limb use at 2, 4 and 6 weeks of life.\u0000\u0000Results: HIE rats treated with hASCs traveled further on Rota-rod (p=0.03) when compared to HIE with NS groups. Those in the HIE-hASC group had significant improvement in the usage of the affected limb at week 6 (p=0.03) compared to those with HIE and NS. Rats receiving hASCs post HIE had less cortical atrophy compared to those with HIE and NS.\u0000\u0000Conclusions: Rats with HIE treated with hASCs showed improvement in long-term neurodevelopmental aspects and decreased cortical atrophy compared to HIE control group.","PeriodicalId":92771,"journal":{"name":"Cooper Rowan medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45516883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Establishment of an in vivo Streptozotocin-Induced Type 1 Diabetes Model Recapitulating Early Brain and Retinal Fibrosis","authors":"Savitha Racha, Lynn Manganiello, Igor Kuzin, Mary K. Carney, Alvin Mercado, Kara Aplin, Madeline King, Ryan Schmidt, Brian Roberts, Matthew Scott Salzman","doi":"10.31986/issn.2578.3343_vol5iss1.1","DOIUrl":"https://doi.org/10.31986/issn.2578.3343_vol5iss1.1","url":null,"abstract":"Background: The addition of an addiction medicine consult service has been shown to improve mortality and decrease hospital costs but its impact on the proportion of patients discharged against medical advice (DAMA) and in-hospital initiation of medication for opioid use disorder (MOUD) has not been examined.\u0000\u0000Methods: A retrospective before-after cohort study was performed at an urban, academic medical center between January 1, 2015 and November 1, 2019. We included adult patients with infective endocarditis and injection drug use determined by admitting diagnosis ICD-9 or ICD-10 codes or documentation within the history section of electronic health recordEHR. Our institution implemented a formal addiction medicine consult service on July 1, 2018. We determined the proportion of patients DAMA and the proportion of patients started on MOUD among patients in the pre-intervention (i.e. hospitalized before July 1, 2018) and intervention (i.e. hospitalized July 1, 2018 or after) groups.\u0000\u0000Results: A total of 171 patients among hospitalized patients with injection drug use-associated infective endocarditis were included with 119 patients in the pre-intervention group and 52 patients in the intervention group. There was no statistically significant difference in patients DAMA [19% vs 15%, absolute risk difference 4.6% (95% confidence interval -8.6% to 17.7%)] between the intervention and pre-intervention groups. However, there was an increase in the proportion of inpatient MOUD initiation in the intervention group compared to the pre-intervention group [56% vs 21%, absolute risk difference 35% (95% confidence interval 19% to 50%)].\u0000\u0000Conclusions: The initiation of an addiction medicine consult service was associated with a higher proportion of MOUD initiation but there was no statistically significant association with the proportion of patients DAMA.","PeriodicalId":92771,"journal":{"name":"Cooper Rowan medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47494109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Behavioral Health Models to Understand High-Risk Prenatal Patient Adherence to Visit Schedule in Camden","authors":"Olivia Nicolais-Julian, MD, Michael Monaghan, MD, Jocelyn Mitchell-Williams MD, PhD","doi":"10.31986/issn.2578.3343_vol4iss1.9","DOIUrl":"https://doi.org/10.31986/issn.2578.3343_vol4iss1.9","url":null,"abstract":"Methods: This study included adult, English speaking patients of the high-risk prenatal clinic at Cooper University Hospital that missed at least one appointment. We completed three, one hour focus groups with seven participants. Constant comparison analysis was used to determine common themes discussed by participants. Axial coding and basic unit descriptors were defined by both facilitators to determine common themes discussed during the focus group sessions.\u0000Results: We identified two main themes in regards to patient visit non-adherence in our population: logistic issues and perceived relationship issues between the patient and the care team. Logistic issues included issues with rescheduling, seeing different providers, parking, wait time and office hours. In regards to patient-care team relationships, subjects frequently brought up issues with respect, feeling heard by providers, communication and professionalism. All seven patients identified at least one of the five domains of logistic barriers as a concern. Five of the seven participants identified an issue across the four domains of relationship issues.\u0000Discussion: The focus group analysis illustrated recurrent themes of logistic barriers and deficiencies in patient-care team relationships that contributed to high-risk prenatal visit non-adherence. A follow-up survey study is necessary to quantitatively assess the most prominent reasons for visit non-adherence based on the themes identified in our study.","PeriodicalId":92771,"journal":{"name":"Cooper Rowan medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48775534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breast Implant-Associated Anaplastic Large Cell Lymphoma: A Case Report","authors":"J. Tan, Jamie Johnson-Eddy, Wesley Tang, Yanchun Li","doi":"10.31986/issn.2578.3343_vol4iss1.10","DOIUrl":"https://doi.org/10.31986/issn.2578.3343_vol4iss1.10","url":null,"abstract":"This report aims to review a case of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) by comparing the patient's course with the current literature.\u0000\u0000BIA-ALCL is a specific type of T-cell lymphoma that can develop after breast implantation, but has only recently been recognized within the last decade. Although overall rare, certain types of breast implants have increased association with developing subsequent lymphoma. This case occurred after mastectomy with breast reconstruction for unilateral invasive ductal carcinoma with a textured, saline Allergan breast implant. BIA-ALCL manifested and was symptomatic nine years after implantation.","PeriodicalId":92771,"journal":{"name":"Cooper Rowan medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47338447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Establishment of an in vivo Streptozotocin-Induced Type 1 Diabetes Model Recapitulating Early Brain and Retinal Fibrosis","authors":"Kia S Bourdot, Lucy Dawson, I. Kuzin, Arturo Bravo-Nuevo, Z. Antonello","doi":"10.31986/issn.2578.3343_vol4iss1.7","DOIUrl":"https://doi.org/10.31986/issn.2578.3343_vol4iss1.7","url":null,"abstract":"INTRODUCTION: Diabetes has risen to one of the top American public health concerns. The hyperglycemic state of chronic diabetes leads to microvascular and macrovascular changes that predispose patients to delayed wound healing and organ fibrosis. The validation of models to specifically detect early, quantifiable fibrotic changes seen in the diabetic state is of fundamental importance for understanding the diabetic pathophysiology and exploring earlier management options. Here, we investigated if we could detect early signs of internal fibrosis in a streptozotocin (STZ) diabetic mouse model by quantifying\u0000α-SMA expression in various organs using flow cytometry.\u0000METHODS: We used a low-dose STZ-induced T1DM model. T1DM was confirmed via sustained hyperglycemia (>250mg/dl) over 8-10 weeks. Delayed healing of full thickness wounds was confirmed by tracking wound healing progression over two weeks. Wounded and unwounded skin samples were analyzed histologically to quantify collagen deposition as a sign of fibrosis. Organ fibrosis was assessed in a semi-high-throughput manner using flow cytometry to quantify the percentage of alpha-Smooth Muscle Actin (α-SMA) positive cells in diabetic versus normoglycemic controls.\u0000RESULTS: Combining STZ with post-injection glucose treatment yielded highly efficient 100% pathogenesis with 100% survival. Diabetic mice showed signs of hyperglycemia, polyuria, and delayed wound healing. Histological analysis indicated a greater increase in epidermal height and lower levels of collagen deposition in diabetic wounds. After 10-12 weeks of hyperglycemia, we observed elevated\u0000α-SMA in brain and retinal tissues.\u0000 \u0000DISCUSSION: The STZ model has previously presented cumbersome, costly, and time-intensive limitations for the study of diabetic complications. Here we tested a quantitative method for detecting early signs of fibrosis using flow cytometry. The higher percentage of α-SMA positive cells in retinal and brain tissue of diabetic mice suggests fibrosis of these tissues. We argue that this is a suitable method to study early diabetic complications.\u0000Keywords: diabetes, hyperglycemia, fibrosis, murine","PeriodicalId":92771,"journal":{"name":"Cooper Rowan medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47952899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}