Sokoto journal of medical laboratory science最新文献

{"title":"Diagnostic challenges in monitoring and evaluating annual ivermectin (Mectizan®) treatment intervention strategy to determine onchocerciasis elimination status","authors":"H. Osue, H. Inabo, S. Yakubu, P. Audu","doi":"10.4314/sokjmls.v7i3.9","DOIUrl":"https://doi.org/10.4314/sokjmls.v7i3.9","url":null,"abstract":"Ability to accurately detect an active infection depends largely on the high accuracy (sensitivity and specificity) of a diagnostic test. There is no single diagnostic tool that meets the criteria of been simple, measurable, accurate, repeatable and timely (SMART). Combining the screening and confirmation tests have been relied upon in determining the true epidemiological situation of ongoing ivermectin or Mectizan® treatment intervention strategy. Antibody detection assays have been evaluated as screening tools using various formats like different types of agglutination protocol, enzyme linked immunosorbent assays (ELISA) and nucleic acid amplification tests (NAAT). Despite these developments, presence of any stage of the parasite antigen, microfilaria (fourth larva, L4) and macrofilaria (adult worm) confirms active infection. The standard microscopic examination of skin snips for emerged microfilaria obtained with a scleral biopsy punch is capable of spreading blood viral diseases. The sensitivity of the test has decreased following post-treatment with ivermectin and surveillance for recrudescence is inevitable. On one hand, the time preceding when parasite materials liberated as against when detectable immune responses were invoked decreases the sensitivity of serological tests. The DNA molecular based tests with the attendant complexity of protocol remained a technical barrier that has been surmounted with the development of loop- mediated isothermal amplification (LAMP). This technique amplifies DNA with high specificity, sensitivity and rapidity under isothermal conditions. It will serve as alternative definitive diagnostic test to skin microfilaria detection. A combination of LAMP with IgG4 antibodies against O. volvulus 16 kiloDalton (Ov16) antigen is used as a rapid qualitative test of human finger-prick blood, serum and plasma now widely applied in disease endemic countries. Also, diethyl carbamazine (DEC) patch skin test for popular eruption indicative of positive infection attracted further re-evaluation as non-invasive screening tool devoid of skin biopsy and blood sample collection.","PeriodicalId":92723,"journal":{"name":"Sokoto journal of medical laboratory science","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83694246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and antimicrobial susceptibility pattern of uropathogenic organisms among diabetic patients attending State Specialist Hospital, Maiduguri Nigeria.","authors":"Wathanafa Madu, Musa Joseph Bamaiyi, M. Akinola, Muhammed Talle, Hamidu M. Ibrahim, I. Abdullahi, M. Mustapha, M. Baba, B. Oderinde","doi":"10.4314/sokjmls.v7i3.10","DOIUrl":"https://doi.org/10.4314/sokjmls.v7i3.10","url":null,"abstract":"Urinary tract infection (UTI) is the colonization of the urinary tract by pathogenic microorganisms. There is paucity of data on the development of multidrug resistant uropathogenic strains associated with Diabetes Mellitus (DM). In this cross-sectional study we investigated a total of three hundred and thirty (330) known diabetes mellitus (DM) patients, comprising of 06 (1.8%) Type I DM, 296 (89.7%) Type II DM and 28 (8.5%) Gestational Diabetes patients aged 21 to 80 years. The subjects consisted of 150 males (45.5%) and 180 (54.5%) females. Urine culture was carried out on CLED, MacConkey and blood agar and Kirby Bauer disc diffusion for antimicrobial susceptibility testing was carried out to determine the susceptibility of the isolated organisms to commonly used antimicrobials in the study area. The study revealed that one hundred and twenty-two (37%) yielded significant bacterial growth. The percentage distribution of the organisms isolated are as follows; Staphylococci (10.6%), Klebsiella spp. (13.2%), Coliforms spp. (13.9%), Staphylococcus aureus (24.6%) and Escherichia coli has the highest occurrence of (37.7%). Gram negative bacteria isolated were highly susceptible to Ciprofloxacin (10 μg), tarivid (10 μg) and streptomycin (30 μg); and moderately- to poorly sensitive to the other antibiotics used in the study. In conclusion female diabetics were at a higher risk for UTIs that than males (p=0.000) and low educational level/social class was also a risk factor (p=0.04) when compared to subjects of higher educational level/ social class.","PeriodicalId":92723,"journal":{"name":"Sokoto journal of medical laboratory science","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79754842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibiogram of bacterial isolates obtained from infants and children at the University of Calabar Teaching Hospital (UCTH).","authors":"E. Ibeneme, Z. Ali, G. P. Bebia, Joy Chinweokwu Ezema, J. Boniface","doi":"10.4314/sokjmls.v7i3.4","DOIUrl":"https://doi.org/10.4314/sokjmls.v7i3.4","url":null,"abstract":"The gradual increase in antimicrobial resistance in children is a major challenge in the field of hospital epidemiology and medical microbiology. This study was conducted to investigate the susceptibility pattern of commonly used antimicrobial agents against bacterial isolates in children attending UCTH. Fifty clinical specimens; blood, urine, eye, ear and wound swap were collected from infants and children 1-day old to 9 years. About 2mL of the blood was dispensed into Brain Heart infusion broth (10ml) contained in a Bijou bottle and incubated for 2 days at 37°C. Midstream urine samples were collected into sterile universal containers and cultured on blood and CLED agar using the Leigh and Williams paper strip method, while sterile swab-stick was used to collect ear and eye specimen (discharge). The ear specimens were cultured on CLED and blood agar while the eye swap on CLED and chocolate agar. Isolates susceptibility was tested on gentamicin, erythromycin, Zithromax, ampicillin, amoxicillin and penicillin using disc diffusion method by Kirby-Bauer. Of the 50 subjects examined, a total of 39 bacterial isolates were obtained from the 36(72%) culture positive samples. S. aureus was the most isolated 22(56.4%), followed by P. aeruginosa 7(17.9%), Streptococci, Coliform, and Proteus were 3(7.7%), 6(15.4%) and 1(2.6%) respectively. Female children had more bacterial isolates 19(73.1%) compared to male 17(70.1%). The isolates were more sensitive to gentamicin 25(64%), followed by zithromax 23(59%), erythromycin 16(41%) and ampicillin 12(31%). The isolates were less sensitive to Penicillin 2(5) and Amoxicillin 10(26), multi resistance was seen in 14(35.9%) of the isolates. Resistance to antibiotics is on the rise and babies are particularly at increased risk because of lower immunity. The study recommends the need for the development of alternative therapy.","PeriodicalId":92723,"journal":{"name":"Sokoto journal of medical laboratory science","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89978742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of melatonin consumption on some oxidative stress biomarkers of stress-exposed pregnant rats.","authors":"B. Aliyu, U. Mohammed, Y. Oyeniyi","doi":"10.4314/sokjmls.v7i3.5","DOIUrl":"https://doi.org/10.4314/sokjmls.v7i3.5","url":null,"abstract":"Melatonin acts as a free radical scavenger and nuclear and mitochondrial DNA from free radicals-induced damage. This study was designed to test the hypothesis that melatonin may mitigate the effect of restraint stress in pregnant rats by mechanisms associated with stimulation of antioxidant enzymes and reduction in malondialdehyde (MDA) levels. Pregnant Wistar rats aged between 10-12 weeks and weighing 125±5.5g (mean ±SEM), were randomly divided into three groups (n= 8 each) that had the following treatments: non- stress with vehicle (NSV), stress with vehicle (SV) and stress with melatonin (SM). During the second week of pregnancy, the rats were individually restrained for 1 hour a day for one week. Melatonin (10mg/kg) was administered orally to the treatment group (SM) every day throughout the stress exposure period while the control groups (NSV and SV) received the vehicle (water). Three weeks after delivery, the rats were euthanized and the antioxidant enzymes [catalase (CAT), superoxide dismutase (SOD), and glutathione peroxidase (GPx)] and MDA levels were measured. The CAT values SV rats were significantly (P<0.001) lower than in NSV and SM rats. The values for GPx and SOD followed the same pattern with CAT. The MDA value obtained from the SV rats were significantly (P<0.0001) higher than the values obtained from NSV and SM rats. The MDA values obtained from the SM rats were significantly (P<0.05) higher than in NSV rats. Results suggest that melatonin helps in countering the effects of restraint stress in pregnant Wistar rats by increasing the serum levels of CAT, GPx and SOD while reducing the serum level of MDA. It is concluded that stress- induced reduction in antioxidant enzymes and attendant increase in lipid peroxidation are mitigated by melatonin.","PeriodicalId":92723,"journal":{"name":"Sokoto journal of medical laboratory science","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81565196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current innovations in medical laboratory diagnosis of Tuberculosis","authors":"S. Obadire, O. Mitsan, I. Ige, O. C. Oke, F.O. Odewusi","doi":"10.4314/sokjmls.v7i3.7","DOIUrl":"https://doi.org/10.4314/sokjmls.v7i3.7","url":null,"abstract":"Tuberculosis (TB) is a major global health problem, ranking as the second highest cause of death from an infectious disease globally, after the human immunodeficiency virus (HIV). Nigeria ranked first in Africa with burden of TB. Tuberculosis is a major public health problem in Nigeria with about 407,000 people infected. The World Health Organization estimates that 120,000 people developed TB in 2019, with 154,000 death of whom, 13% were HIV positive individuals. Among the incident cases, 56% were from the South-East Asia and Western Pacific Regions and one quarter were from Africa. The African continent accounts for the highest rates of cases and deaths relative to population. Traditionally, tuberculosis is mostly being diagnosed by a combination of chest X-rays, the staining of sputum with special dyes followed by microscopy, the growth of Mycobacterium tuberculosis in culture and the Mantoux test. The sputum smear microscopy is easy to do and is very cheap and combined with chest X-rays has been used for a long time by TB control agencies worldwide. However, the sputum smear microscopy (sputum AFB) test has some problems in HIV-positive patients and children also in patients with low bacterial load and in latent TB infections. TB continues to be a complex disease to diagnose and manage due to the chronicity of the disease, the nature of the host-pathogen relationship, and the resulting diversity in its clinical manifestations. Therefore, this review considers recent innovations in TB laboratory diagnosis in conventional (traditional), non- conventional (molecular), serological (immunological) methods and the latest methods of TB diagnosis.","PeriodicalId":92723,"journal":{"name":"Sokoto journal of medical laboratory science","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85726693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection and distribution of multi-drug resistant (MDR) bacterial isolates of clinical and public health significance on hospital fomites and hands of healthcare workers in Mubi General Hospital.","authors":"M. Tula, J. Filgona, Richard Elisha, T. Thomas, F. Iruolaje","doi":"10.4314/sokjmls.v7i3.6","DOIUrl":"https://doi.org/10.4314/sokjmls.v7i3.6","url":null,"abstract":"Despite the progress made in technology and clinical science, bacterial contamination of hospital fomites, healthcare workers, and the entire environment with its attendant consequences constitute a major problem in many countries of the world. One hundred (100) samples including surfaces of hospital fomites and the hands of healthcare workers were analyzed for bacterial growth on selective and or differential media and the bacteria obtained were identified by standard procedure. The bacterial isolates were screened for antibiotic susceptibility test by the Kirby-Bauer agar disk diffusion method. Of the 100 collected, 77 were from inanimate surfaces while 23 were from the hands of healthcare workers. The predominant inanimate surface swabs collected came from beddings (26%), and the least came from door handles (11.0%). The distribution of samples based on wards showed that 54% of the samples were from female wards, 23% from children's wards, and 20% came from the male ward. Out of 100 samples collected from various sites, bacterial growth was observed in 34(34.0%) specimens while the remaining 66 (66%) had no bacterial growth. A total of 72 bacterial isolates were recovered from the 34 specimens. Overall, Staphylococcus aureus (26.0%) was the most common isolate recovered, while the least was Serratia marcescens and Shigella spp. Of the Gram- negative organisms, Pseudomonas aeruginosa was the most predominant specie, whereas Escherichia coli which represents 50.0% (15/30), predominant Enterobacteriaceae specie encountered. Bacterial isolates were mostly recovered from beddings with 24 isolates, and the least was from sink and door handles with 8 isolates each. Resistance to ampicillin by all the isolates was the highest, but with no statistical difference (P=0.468) with resistance to septrin, and gentamycin. Whereas some isolates were resistant to 9-10 antibiotics, others were resistant to 1-2 antibiotics. From these, the multidrug resistance (MDR) phenotype was shown by 35(66.0%) of these isolates. Escherichia coli portrayed 11(73.3%) MDR phenotypes, while Pseudomonas aeruginosa exhibited 8(50.0%) MDR phenotypes. Multiple antibiotic resistance (MAR) index of greater than 0.2 was shown by 38(71.7%) bacterial isolates. Of these, 12(31.6%) and 9(23.7%) were from E. coli and P. aeruginosa respectively. Most of the bacterial isolates that were resistant to at least an antibiotic were commonly isolated from patients' beddings (30.2%), tables (28.3%), and sinks (20.8%). This study, therefore, shows that hands of healthcare workers and inanimate surfaces frequently touched within the hospital environment constitute potential reservoirs for emerging MDR pathogens and may also serve as sources of their transmission.","PeriodicalId":92723,"journal":{"name":"Sokoto journal of medical laboratory science","volume":"93 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76017872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Socio-Demographic Characteristics and Blood Parasites Among Blood Donors in Two Communities in Delta State, Nigeria","authors":"E. E. Lemy, A. G. Edafemakor, A. Egwunyenga","doi":"10.4314/sokjmls.v7i2.10","DOIUrl":"https://doi.org/10.4314/sokjmls.v7i2.10","url":null,"abstract":"A six months' study was conducted to determine the occurrence of blood parasites in blood donors in Eku and Abraka, Delta State. Random sampling was adopted for blood samples collection alongside socio-demographic characteristics. Laboratory analysis using thick and thin films were carried out on samples. The result showed that 59(29.5%) were positive for blood parasites; 46(23.0%) for Plasmodium, 5(5.0%) for Trypanosoma, and 8(4.0%) for microfilaria. Parasite prevalence was highest in the age-group 45-49 years. Female showed relatively higher prevalence (30.6%) compared to male (29.3%). There was no significant difference in blood parasites prevalence based on gender of the subjects. Blood group B had the dominant prevalence (51.7%). With respect to occupation, self-employed donors had higher prevalence (38.9%). In addition, the rural-urban prevalence was skewed towards rural blood donors (39.7%) with no statistical difference, in respect to residence.  PCV of donors showed no clear patterns and there was no association between PCV and prevalence of blood parasites (p>0.05). The results therefore indicate that there is relatively high prevalence of blood parasites among the blood donors which call for the attention of the authority concerned.","PeriodicalId":92723,"journal":{"name":"Sokoto journal of medical laboratory science","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75107133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"De Ritis Ratio and related Parameters among Breast Cancer Patients in a Southern Nigeria Population","authors":"E. Akwiwu, D. Akpotuzor, J. Udosen, J. Akpotuzor","doi":"10.4314/sokjmls.v7i2.11","DOIUrl":"https://doi.org/10.4314/sokjmls.v7i2.11","url":null,"abstract":"De Ritis described the ratio between the serum levels of liver enzymes; aspartate transaminase (AST) and alanine transaminase (ALT). The central role of the liver in metabolism makes it a necessity that it functions optimally during chemotherapeutic administration, hence the consideration of associated parameters in the management of breast cancer. This study was conducted in University of Calabar Teaching Hospital, Calabar. It included 40 cases of pathologically diagnosed breast cancer female patients who were accessing post-operative chemotherapy. Another 40 apparently healthy females drawn from the general population served as controls. Ethical approval and written informed consent were duly sought and obtained. The present study measured the levels of total and conjugated bilirubin as well as the enzyme activities for a spartate aminotransferase, alanine aminotransferase and alkaline phosphatase. Additionally, Unconjugated bilirubin derived from total and conjugated bilirubin as well as De Ritis ratio computed from aspartate aminotransferase and alanine aminotransferase were calculated. Standard colorimetric methods were used to determine the measured parameters, while derived parameters were calculated. The data obtained were analyzed in Statistical Package for Social Sciences (SPSS) using students t-test at 95% confidence level with p-value of ≤ 0.05. Apart from alanine aminotransferase that of the chemotherapy courses showed some observable effect on both derived parameters; Unconjugated Bilirubin and De Ritis ratio. The later showed a stable pattern of increment after commen cement of post-operative chemotherapy. This study indicates that routine assessment of hepatic function and De Ritis ratio should be determined as part of breast cancer management.","PeriodicalId":92723,"journal":{"name":"Sokoto journal of medical laboratory science","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81794633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential Differential Marker in the Diagnosis of Leptospirosis","authors":"S. Hudu, M. I. Saeed","doi":"10.4314/sokjmls.v7i2.4","DOIUrl":"https://doi.org/10.4314/sokjmls.v7i2.4","url":null,"abstract":"Human leptospirosis, or commonly known as the “rat urine disease” is a zoonotic disease caused by a bacterium called Leptospira sp. acquired via the urine of animal carriers. It is believed that the incidence rate of leptospirosis has been under-reported due to its unspecific clinical Symptoms and the limitations of current diagnostic methods. Leptospirosis can be effectively treated with antibiotics in the early stage, and it is a curable disease. But the accuracy to diagnose the infection is rarely achieved. The present study investigated the plasma protein profiles of lleptospirosis patients who presented with different clinical presentations, and compared them against two control groups consisting of dengue patients and healthy individuals. The plasma protein digests were analyzed using a shotgun approach by liquid chromatography-tandem mass spectrometry (LC-MS/MS) as described by the manufacturer. The proteins detected in every leptospirosis patient and with at least two-fold differential expression with statistical significance (p<0.05) compared to the control groups were identified. Lipopolysaccharide (LPS)-binding protein (LBP) is reported as the only plasma protein that fulfilled the selection criteria. The characteristics and roles of LBP in the immune system during infections are reviewed. Compared to the other proteome-based studies on human leptospirosis. The present study is the first that reported LBP as one of the significant differentially expressed proteins. Potential of coupling LBP with other disease-specific biomarkers in clinical diagnosisand prognosis should be considered.","PeriodicalId":92723,"journal":{"name":"Sokoto journal of medical laboratory science","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90683598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Assessment of Compliance with Infection Control Protocols amongst Dental Health Care Personnel in a Tertiary Health Facility in Southern Nigeria.","authors":"Y. Mabiaku, T. O. Mabiaku","doi":"10.4314/sokjmls.v7i2.8","DOIUrl":"https://doi.org/10.4314/sokjmls.v7i2.8","url":null,"abstract":"Dental practitioners are at a very high risk of cross infection due to multiple exposures with patients who may be asymptomatic carriers of infectious diseases. The study focused on Dental Health Care Personnel who are presently working in the Dental Centre of the University of Benin Teaching Hospital (UBTH) and it assessed the compliance to infection control practices. A self-administered questionnaire containing closed and open-ended questions was used. Information sought included; socio-demographic characteristics of respondents, duration as DHCP, knowledge of transmissible infections in dental clinics, level of compliance with infection control protocols and reasons for non-compliance. One hundred and thirty-five (135) Dental Health Care Personnel of the University of Benin Teaching Hospital were enrolled for this study. However, a total of one hundred and eleven questionnaires were properly filled and returned for analysis, giving a response rate of 82.2%. Fifty-two (46.8%) respondents, had good compliance, twelve (10.8%), had fair compliance and forty-seven (42.3%) had poor level of compliance. Although, the average level of compliance of the DHCP of UBTH was good, some basic important principles were not being observed. The study concludes in the affirmative that strict observance of standard infection control practices is possible.","PeriodicalId":92723,"journal":{"name":"Sokoto journal of medical laboratory science","volume":"373 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80518117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}