Journal of endocrinology and thyroid research最新文献

{"title":"Review: Testosterone Replacement Therapy. Through 2018 Updates, should we Still Consider it a Prostate Cancer Risk Factor?","authors":"Mohamed H. Noureldin","doi":"10.19080/jetr.2019.04.555630","DOIUrl":"https://doi.org/10.19080/jetr.2019.04.555630","url":null,"abstract":"","PeriodicalId":92667,"journal":{"name":"Journal of endocrinology and thyroid research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46038894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Amylin in Thyroid Cancer","authors":"M. Abdalla","doi":"10.19080/jetr.2019.04.555631","DOIUrl":"https://doi.org/10.19080/jetr.2019.04.555631","url":null,"abstract":"","PeriodicalId":92667,"journal":{"name":"Journal of endocrinology and thyroid research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49385899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Assessment of Cardiac Risk Factors on Subclinical Hypothyroidism in Coronary Heart Disease Patients","authors":"Xiaomei Yao","doi":"10.19080/jetr.2019.04.555629","DOIUrl":"https://doi.org/10.19080/jetr.2019.04.555629","url":null,"abstract":"Purpose: Subclinical hypothyroidism (SCH) is defined as a condition which shows an elevated serum thyroid-stimulating hormone (TSH) in the presence of normal free triiodothyronine (FT3) and tetraiodothyronine (FT4) levels. The effect of conventional factors for coronary heart disease (CHD) on the severity of SCH remains uncertain. Our aim was to evaluate the cardiac risk factors on various degrees of SCH in a cohort of CHD patients. Methods: CHD patients were retrospectively divided into euthyroid, mild and severe SCH groups according to their thyroid functional status. Heath data from patients, including present and past history, results of blood biochemistry and ultrasound echocardiography were analyzed using univariate and multivariate logistic regression. Results: Among the CHD patients with euthyroidism (N =118), mild SCH (N=70) and severe SCH (N=29), 5 of 13 related factors, including gender, smoking history, LVEF, E/A and antithyroid peroxidase autoantibody (anti-TPO) positive were significantly different among the three groups (p<0.05). Interestingly, according to the results of univariate logistic regression, patients without smoking history were more likely to have mild SCH (OR=0.125, p<0.001) and severe SCH (OR=0.187, p=0.009). Likewise, patients with low HDL-C level were more likely to have severe SCH (OR=0.401, p=0.030). However, according to the results of multivariate logistic regression, females were more inclined to have mild SCH than males (OR=6.380, p<0.001). And patients with anti-TPO positive were more likely to have severe SCH (OR=6.427, p=0.002). Conclusion: Female CHD patients and an anti-TPO positive result were 2 independent factors related to SCH.","PeriodicalId":92667,"journal":{"name":"Journal of endocrinology and thyroid research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68373197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SGLT2-Inhibitor-Induced Euglycemic Diabetic Ketoacidosis in a Newly Diagnosed Type 1 Diabetes Patient","authors":"Dina Omar","doi":"10.19080/jetr.2018.04.555627","DOIUrl":"https://doi.org/10.19080/jetr.2018.04.555627","url":null,"abstract":"","PeriodicalId":92667,"journal":{"name":"Journal of endocrinology and thyroid research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44497738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Giant Hyalinizing Trabecular Carcinoma of the Thyroid Gland in a 20-Years Old Male Patient","authors":"Michael S Papageorgiou","doi":"10.19080/jetr.2018.04.555626","DOIUrl":"https://doi.org/10.19080/jetr.2018.04.555626","url":null,"abstract":"","PeriodicalId":92667,"journal":{"name":"Journal of endocrinology and thyroid research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68373559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Cytology and Thyroid Pathology","authors":"Shabalova Ip","doi":"10.19080/JETR.2018.03.555624","DOIUrl":"https://doi.org/10.19080/JETR.2018.03.555624","url":null,"abstract":"","PeriodicalId":92667,"journal":{"name":"Journal of endocrinology and thyroid research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42924065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insulin Resistance on The Influence of Thyroid Hormone Levels","authors":"Luiz Augusto da Silva","doi":"10.19080/jetr.ms.id.555623","DOIUrl":"https://doi.org/10.19080/jetr.ms.id.555623","url":null,"abstract":"In the present study, the effect of insulin on insulin secretion and insulin sensitivity on insulin sensitivity and insulin sensitivity in patients with diabetes mellitus. Lambardiari et al. [3] evaluated euthyroid subjects in the early stages of diabetes mellitus (DM) and insulin resistance (IR), investigating the association of TH levels with glucose sensitivity by insulin metabolism, and it was found that T3 and T4 levels were reduced in subjects with DM compared to the control group.","PeriodicalId":92667,"journal":{"name":"Journal of endocrinology and thyroid research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45064943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of rs1137101 gene polymorphism of leptin receptor on the development of diabetes mellitus type 2 and obesity","authors":"Ziablitsev Sv","doi":"10.19080/JETR.2018.03.555621","DOIUrl":"https://doi.org/10.19080/JETR.2018.03.555621","url":null,"abstract":"The aim of this research was a study of gene LEPR polymorphism rs1137101 role in diabetes mellitus 2 type development and his influences on the clinical and laboratory data, related to obesity for these patients. 103 patients are inspected, that had the clinically expressed complications. A control group was made by 100 practically healthy persons of corresponding age. The analysis of polymorphic DNA-loci was carried out by the method of polymerase chain reaction in real time (TaqMan® SNP Genotyping Assay). Results showed that allelic polymorphism of rs1137101 (223Gln>Arg) had been associated with diabetes mellitus 2 types development: allele Gln promotes, while allele Arg – reduces (OR=1.5; P=0.039) the risk of its development. Presence allele Gln for diabetic patients assists development of obesity and his displays, namely – to the higher values of body mass index and HOMA-IR, and also to the greater leptin and triglycerides blood levels on a background reduction of high-density lipoproteides maintenance. The risk of developing obesity in these patients is increased by 1.8 times.","PeriodicalId":92667,"journal":{"name":"Journal of endocrinology and thyroid research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44490819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Small Pheochromocytomas: Clinical, Diagnostic and Perioperative Issues of Disease","authors":"Cheren'ko Sm","doi":"10.19080/jetr.ms.id.555619","DOIUrl":"https://doi.org/10.19080/jetr.ms.id.555619","url":null,"abstract":"Small Pheochromocytomas: Clinical, Diagnostic and Perioperative Issues of Disease Introduction: Pheochromocytoma (P) is considered as relatively rare adrenal tumor with clinical manifestation after reaching the size of 4-6cm. Meanwhile, it’s supposing that small P can be not rare found within different diagnostic imagination. Some of these, being clinically silent, can cause serious cardio-vascular risk undergoing unrelated medical procedures. We compared clinical course, peculiarities of diagnostics and treatment of small P (less than 3cm) and bigger P on the basement of own clinical experience among patients underwent adrenalectomy on proven or suspected P. Material and methods: Group of small P was comprised by 14 patients aged from 21 to 62 years with mean size of tumor 23mm (range: 4-29mm). Control group consisted of 35 patients corresponded on age (23-75 years) with mean P diameter of 56mm (range: 30-127mm). Small P comprised 8% of all 175 patients with P operated on during the last 19 years in endocrine surgery hospital from the whole group of 967 adrenalectomies. Prevalence of women and right side lesions characterized both groups. Discussion: Principal differences between groups were less prominent clinical activity (any symptoms were detected in half of small P) with less level of catecholamines and metanefrines in lab examination of serum and urea of small P patients. Computed tomography was often the first but not targeted diagnostic step. Silent clinical course was the main reason that small P have been discovered predominantly incidentally with no blockage of alpha-adrenergic receptors before surgery in 6 of 14 patients. Most of them had a critical elevation of blood pressure during operation (43% against 9% in control group; p<0.05). Despite small size and mild catecholamine excess in small P group, 4 from 14 patients (29%) experienced episodes of potentially harmful hypertensive crisis during unrelated medical procedures in the past. All small P were treated successfully by laparoscopic adrenalectomy. Most of patients became free from hypertension. Conclusion: Small P may carry actual risk of unexpected hypertensive crisis during any unrelated medical procedures. The clinical course of small P is hidden in half of patients and laboratory investigations are interfered with mild elevation of biochemical markers. Laparoscopic adrenalectomy is safe mode of treatment of small P in case of adequate preparation.","PeriodicalId":92667,"journal":{"name":"Journal of endocrinology and thyroid research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43530251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Familial Nonmedullary Thyroid Carcinoma (Fnmtc): Molecular Advances with the New Sequencing Technologies","authors":"Erika Urbano de Lima","doi":"10.19080/jetr.ms.id.555618","DOIUrl":"https://doi.org/10.19080/jetr.ms.id.555618","url":null,"abstract":"","PeriodicalId":92667,"journal":{"name":"Journal of endocrinology and thyroid research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45445724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}