Edward Goacher, Stefan Yardanov, Richard Phillips, Alexandru Budu, Edward Dyson, Marcel Ivanov, Gary Barton, Mike Hutton, Adrian Gardner, Nasir A. Quraishi, Gordan Grahovac, Josephine Jung, Andreas K. Demetriades, Pierluigi Vergara, Erlick Pereira, Vasileios Arzoglou, Jibin Francis, Rikin Trivedi, Benjamin M. Davies, Mark R.N. Kotter
{"title":"Cost-effectiveness of surgery for degenerative cervical myelopathy in the United Kingdom","authors":"Edward Goacher, Stefan Yardanov, Richard Phillips, Alexandru Budu, Edward Dyson, Marcel Ivanov, Gary Barton, Mike Hutton, Adrian Gardner, Nasir A. Quraishi, Gordan Grahovac, Josephine Jung, Andreas K. Demetriades, Pierluigi Vergara, Erlick Pereira, Vasileios Arzoglou, Jibin Francis, Rikin Trivedi, Benjamin M. Davies, Mark R.N. Kotter","doi":"10.1080/02688697.2024.2346566","DOIUrl":"https://doi.org/10.1080/02688697.2024.2346566","url":null,"abstract":"Degenerative cervical myelopathy (DCM) is the commonest cause of adult spinal cord dysfunction worldwide, for which surgery is the mainstay of treatment. At present, there is limited literature on ...","PeriodicalId":9261,"journal":{"name":"British Journal of Neurosurgery","volume":"44 1","pages":""},"PeriodicalIF":1.1,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140834566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel Thompson, Adam Williams, Peter C. Whitfield, Peter Hutchinson, Nicholas Phillips, David Cromwell, Adel Helmy, On behalf of the National Neurosurgical Audit Programme
{"title":"Surgical recovery from the COVID-19 pandemic in English adult neurosurgical centres","authors":"Daniel Thompson, Adam Williams, Peter C. Whitfield, Peter Hutchinson, Nicholas Phillips, David Cromwell, Adel Helmy, On behalf of the National Neurosurgical Audit Programme","doi":"10.1080/02688697.2024.2339355","DOIUrl":"https://doi.org/10.1080/02688697.2024.2339355","url":null,"abstract":"The COVID-19 pandemic required a change in resource priority from Neurosurgical care in order to treat medically unwell patients suffering from the complications of COVID-19 infections. We demonstr...","PeriodicalId":9261,"journal":{"name":"British Journal of Neurosurgery","volume":"11 1","pages":""},"PeriodicalIF":1.1,"publicationDate":"2024-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140627405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Calcifying pseudoneoplasms of the neuraxis (CAPNON) in foramen magnum (cervicomedullary junction) region: a case report and review of the literature","authors":"Omar Atallah, Kathreena M Kurian, Mario Teo","doi":"10.1080/02688697.2024.2339354","DOIUrl":"https://doi.org/10.1080/02688697.2024.2339354","url":null,"abstract":"Calcifying pseudoneoplasms of the neuraxis (CAPNON) is an extremely rare tumor, with nearly 150 cases have been reported in the literature. We present a case of CAPNON at foramen magnum (cervicomed...","PeriodicalId":9261,"journal":{"name":"British Journal of Neurosurgery","volume":"53 1","pages":""},"PeriodicalIF":1.1,"publicationDate":"2024-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140600094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alisa Arnautovic, Joseph Mijares, Emir Begagić, Adi Ahmetspahić, Mirza Pojskić
{"title":"Four-level ACDF surgical series 2000–2022: a systematic review of clinical and radiological outcomes and complications","authors":"Alisa Arnautovic, Joseph Mijares, Emir Begagić, Adi Ahmetspahić, Mirza Pojskić","doi":"10.1080/02688697.2024.2337020","DOIUrl":"https://doi.org/10.1080/02688697.2024.2337020","url":null,"abstract":"The primary objective of this investigation is to systematically scrutinize extant surgical studies delineating Four-Level Anterior Cervical Discectomy and Fusion (4L ACDF), with a specific emphasi...","PeriodicalId":9261,"journal":{"name":"British Journal of Neurosurgery","volume":"65 1","pages":""},"PeriodicalIF":1.1,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140600391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jamie F. M. Brannigan, Conor S. Gillespie, Gideon Adegboyega, Matthew Watson, Keng Siang Lee, Adele Mazzoleni, Edward Goacher, Orla Mantle, Vian Omar, Githmi Gamage, Alvaro Yanez Touzet, Oliver Mowforth, Will Thomas, James Uprichard, Peter J. Hutchinson, Daniel J. Stubbs, Benjamin M. Davies, On Behalf Of The ICENI Working Group
{"title":"Impact of antithrombotic agents on outcomes in patients requiring surgery for chronic subdural haematoma: a systematic review and meta-analysis","authors":"Jamie F. M. Brannigan, Conor S. Gillespie, Gideon Adegboyega, Matthew Watson, Keng Siang Lee, Adele Mazzoleni, Edward Goacher, Orla Mantle, Vian Omar, Githmi Gamage, Alvaro Yanez Touzet, Oliver Mowforth, Will Thomas, James Uprichard, Peter J. Hutchinson, Daniel J. Stubbs, Benjamin M. Davies, On Behalf Of The ICENI Working Group","doi":"10.1080/02688697.2024.2333399","DOIUrl":"https://doi.org/10.1080/02688697.2024.2333399","url":null,"abstract":"A chronic subdural haematoma (CSDH) is a collection of aged blood between the dura and the brain, typically treated with surgical evacuation. Many patients with CSDH have comorbidities requiring th...","PeriodicalId":9261,"journal":{"name":"British Journal of Neurosurgery","volume":"245 1","pages":""},"PeriodicalIF":1.1,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140600093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical characteristics of aneurysmal subarachnoid haemorrhage complicated by Takotsubo cardiomyopathy resulting in good neurological outcome","authors":"Takafumi Kawasaki, Taishi Nakamura, Makoto Ohtake, Taisuke Akimoto, Hiroshi Manaka, Koichi Hamada, Katsumi Sakata, Masayuki Iwashita, Ichiro Takeuchi, Tetsuya Yamamoto","doi":"10.1080/02688697.2024.2334432","DOIUrl":"https://doi.org/10.1080/02688697.2024.2334432","url":null,"abstract":"Takotsubo cardiomyopathy (TC) is a well-known complication of subarachnoid haemorrhage (SAH), often accompanied by neurogenic myocardial dysfunction. Although TC has been reported to be associated ...","PeriodicalId":9261,"journal":{"name":"British Journal of Neurosurgery","volume":"121 1","pages":""},"PeriodicalIF":1.1,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140600298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nithish Jayakumar, Aasim Hagroo, Oliver Kennion, Damian Holliman
{"title":"A cross-sectional survey of patient perceptions of the National Neurosurgical Audit Programme (NNAP).","authors":"Nithish Jayakumar, Aasim Hagroo, Oliver Kennion, Damian Holliman","doi":"10.1080/02688697.2024.2334433","DOIUrl":"https://doi.org/10.1080/02688697.2024.2334433","url":null,"abstract":"<p><strong>Background: </strong>The National Neurosurgical Audit Programme (NNAP) publishes mortality outcomes of consultants and neurosurgical units across the United Kingdom. It is unclear how useful outcomes data is for patients and whether it influences their decision-making process. Our aim was to identify patients' perceptions and understanding of the NNAP data and its influences.</p><p><strong>Materials and methods: </strong>This single-centre study was conducted in the outpatient neurosurgery clinics at a regional neurosurgical centre. All adult (age ≥ 18) neurosurgical patients, with capacity, were invited to take part. Native and non-native English speakers were eligible. Statistical analyses were performed on SPSS v28 (IBM). Ethical approval was obtained.</p><p><strong>Results: </strong>A total of 84 responses were received (54.7% females). Over half (51.0%) of respondents felt that they understood a consultant's mortality outcomes. Educational level determines respondents' understanding (χ<sup>2</sup>(8) = 16.870; <i>p</i> = .031). Most respondents were unaware of the NNAP (89.0%). Only a third of respondents (35.1%) understood the funnel plot used to illustrate mortality.</p><p><strong>Conclusions: </strong>Most patients were unaware of the NNAP and most did not understand the data on the website. Understanding of mortality data seemed to be related to respondents' educational level which would be important to keep in mind when planning how to depict mortality data.</p>","PeriodicalId":9261,"journal":{"name":"British Journal of Neurosurgery","volume":" ","pages":"1-4"},"PeriodicalIF":1.1,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140334752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Weixin Lu, Cheng Jiang, Zening Wang, Yi Chen, Ruobing Bai, Guizhong Yan, Gang Wang, Haijun Ren
{"title":"Lactic acid, neuron-specific enolase, and blood-brain barrier index after a severe traumatic brain injury: a prospective study.","authors":"Weixin Lu, Cheng Jiang, Zening Wang, Yi Chen, Ruobing Bai, Guizhong Yan, Gang Wang, Haijun Ren","doi":"10.1080/02688697.2020.1823938","DOIUrl":"10.1080/02688697.2020.1823938","url":null,"abstract":"<p><strong>Objective: </strong>To explore the clinical significance of dynamic monitoring of cerebrospinal fluid (CSF) and serum Lactic acid(Lac), neuron-specific enolase (NSE), and the blood-brain barrier (BBB) index in evaluating the condition and prognosis after a severe traumatic brain injury (TBI).</p><p><strong>Methods: </strong>A total of 52 severe TBI patients admitted to the Department of Neurosurgery within 24 hours after injury were dynamically monitored. CSF and serum samples were collected on the 1st, 3rd, and 7th day after a severe TBI to monitor the changes in Lac, NSE, and the BBB index. Intracranial pressure (ICP), Glasgow coma scale (GCS), and 6-month Glasgow outcome scale-extended (GOS-E) were tested. According to the results of GOS-E, the patients were divided into two groups (i.e. the poor prognosis group and good prognosis group). Statistical analysis was conducted to investigate the clinical significance of dynamic monitoring of CSF and serum Lac, NSE, and BBB index after a severe TBI.</p><p><strong>Results: </strong>After a severe TBI, the levels of Lac, NSE, and BBB in CSF and serum were significantly higher than those in the normal range. Lac, NSE, and the BBB index did not correlate with ICP (except serum Lac) but had correlations with GCS and post-injury 6 months post-injury (except serum Lac). Moreover, the correlations between Lac, NSE, and BBB index were statistically significant (<i>p</i> < 0.05): CSF Lac and CSF NSE; CSF Lac and serum NSE; Lac and BBB index of CSF; Lac and BBB index of CSF; NSE and CSE of serum; CSF NSE and BBB index; and serum NSE and BBB index. Additionally, serum NSE is correlated with NSE in CSF (<i>p</i> < 0.05).</p><p><strong>Conclusion: </strong>After a severe TBI, dynamic monitoring of CSF and serum Lac, NSE, and BBB index has the potential to assess the condition, predict the prognosis, and have clinical significance.</p>","PeriodicalId":9261,"journal":{"name":"British Journal of Neurosurgery","volume":" ","pages":"220-224"},"PeriodicalIF":1.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38453878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cerium oxide nanoparticles as a new neuroprotective agent to promote functional recovery in a rat model of sciatic nerve crush injury.","authors":"Milad Soluki, Fariba Mahmoudi, Arash Abdolmaleki, Asadollah Asadi, Abbas Sabahi Namini","doi":"10.1080/02688697.2020.1864292","DOIUrl":"10.1080/02688697.2020.1864292","url":null,"abstract":"<p><strong>Background: </strong>Peripheral nerve injury is a common clinical disorder. The aim of the present study was to investigate the role of cerium oxide nanoparticles on axonal regeneration and functional recovery of the sciatic nerve after a crush injury in the rat model.</p><p><strong>Method: </strong>A total of 40 adult male Wistar rats were divided into four groups. The animals underwent deep anesthesia. Afterward, the right sciatic nerve of rats was exposed and crushed. In two experimental groups, rats were treated intraperitoneally with cerium oxide nanoparticles at the dosage of 20 or 80 mg/kg daily for 1 week. The control group was given a vehicle. Then, during the nerve regeneration motor and sensory function recovery tests, histomorphometric evaluations, histological assessment of gastrocnemius muscle, and gastrocnemius muscle wet weights tests were performed.</p><p><strong>Results: </strong>Results demonstrated that the rate of nerve regeneration increased with the administration of cerium oxide nanoparticle in high doses. Also, the morphometric analysis showed that the number of myelinated fibers and myelin sheath thicknesses was significantly greater in the cerium oxide nanoparticle group versus the control group. Other parameters also improved in the cerium oxide nanoparticle treatment groups compared with the control group.</p><p><strong>Conclusion: </strong>These data indicate that this nanoparticle has therapeutic potential and can be considered as a new treatment for nervous system regeneration.</p>","PeriodicalId":9261,"journal":{"name":"British Journal of Neurosurgery","volume":" ","pages":"301-306"},"PeriodicalIF":1.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39093695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jian Wang, Tao Xu, Lati Pu, Erdan Mai, Hailong Guo, Jun Sheng, Qiang Deng, Yi Liao, Weibin Sheng
{"title":"Release, reduction, and fixation of one-stage posterior approach for basilar invagination with irreducible atlantoaxial dislocation.","authors":"Jian Wang, Tao Xu, Lati Pu, Erdan Mai, Hailong Guo, Jun Sheng, Qiang Deng, Yi Liao, Weibin Sheng","doi":"10.1080/02688697.2020.1861217","DOIUrl":"10.1080/02688697.2020.1861217","url":null,"abstract":"<p><strong>Purpose: </strong>We evaluate the efficacy, safety and indications of single stage posterior release, reduction, and fixation of basilar invagination (BI) with irreducible atlantoaxial dislocation (IAAD).</p><p><strong>Materials and methods: </strong>Seventeen patients with BI and IAAD consecutively underwent one-stage release, reduction, and fixation by a posterior approach from July 2000 to June 2015 were followed up for at least 12 months. There were 8 males. Mean age was 56 35.2 ± 13.8 years (range 12-56). The clinical symptoms and signs of the patients were recorded. Pre- and postoperative imaging examinations were performed. Neurological function was assessed using the Japanese Orthopedic Association (JOA) and Ranawat scores.</p><p><strong>Results: </strong>Average follow-up time was 47.4 months (12-97 months). The JOA score increased from preoperative 4-10 (8.06 ± 2.52) to postoperative 13-16 (15.20 ± 0.62). The preoperative Chamberlain line, McRae line, Wackenheim line, atlantodens interval, and cervico medullary angle were 12.52 ± 5.17 mm, 6.59 ± 3.04 mm, 6.96 ± 4.32 mm, 9.88 ± 1.93 mm, and 115.35 ± 12.40°, respectively. The postoperative values were 2.0 ± 3.67 mm, -3.06 ± 1.85 mm, -1.76 ± 2.88 mm, 1.17 ± 1.18 mm, and 136.76 ± 11.44°, respectively.</p><p><strong>Conclusion: </strong>One-stage release, reduction, and fixation for patients with BI and IAAD through a posterior approach is safe and efficient.</p>","PeriodicalId":9261,"journal":{"name":"British Journal of Neurosurgery","volume":" ","pages":"249-255"},"PeriodicalIF":1.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38395137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}