British Journal of Psychiatry最新文献_第9页

Meritocracy in psychiatry training: abandoning the common good. 精神病学培训中的任人唯贤：放弃共同利益。

IF 8.7 1区医学

British Journal of Psychiatry Pub Date : 2024-07-01 Epub Date: 2024-09-02 DOI: 10.1192/bjp.2024.37

Harrison Howarth, Dominic Kennedy, Mark Berelowitz

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Assisted dying for mental illness: a contemporary concern that requires careful and compassionate consideration. 精神疾病的辅助死亡：当代需要谨慎而富有同情心地考虑的问题。

IF 8.7 1区医学

British Journal of Psychiatry Pub Date : 2024-07-01 DOI: 10.1192/bjp.2024.116

Gin S Malhi

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Medical assistance in dying for mental illness: a complex intervention requiring a correspondingly complex evaluation approach: commentary, Breen. 精神病患者临终医疗救助：一种复杂的干预措施，需要相应复杂的评估方法：评论，布林。

IF 8.7 1区医学

British Journal of Psychiatry Pub Date : 2024-07-01 DOI: 10.1192/bjp.2024.115

Eugene G Breen

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Medical assistance in dying for mental illness: a complex intervention requiring a correspondingly complex evaluation approach. 精神病患者的临终医疗救助：一种复杂的干预措施，需要相应复杂的评估方法。

IF 8.7 1区医学

British Journal of Psychiatry Pub Date : 2024-07-01 DOI: 10.1192/bjp.2024.21

Hamer Bastidas-Bilbao, David Castle, Mona Gupta, Vicky Stergiopoulos, Lisa D Hawke

{"title":"Medical assistance in dying for mental illness: a complex intervention requiring a correspondingly complex evaluation approach.","authors":"Hamer Bastidas-Bilbao, David Castle, Mona Gupta, Vicky Stergiopoulos, Lisa D Hawke","doi":"10.1192/bjp.2024.21","DOIUrl":"10.1192/bjp.2024.21","url":null,"abstract":"Medical assistance in dying for mental illness as a sole underlying medical condition (MAiD MI-SUMC) is a controversial and complex policy in terms of psychosocial and ethical medical practice implications. We discuss the status of MAiD MI-SUMC in Canada and argue for the use of the UK Medical Research Council's framework on complex interventions in programme evaluations of MAiD MI-SUMC. It is imperative to carefully and rigorously evaluate the implementation of MAiD MI-SUMC to ensure an understanding of the multiple facets of implementation in contexts permeated by unique social, economic, cultural and historical influences, with a correspondingly diverse array of outcomes. This requires a complexity-informed programme evaluation focused on context-dependent mechanisms and stakeholder experiences, including patients, service providers and other people affected by the policy. It is also important to consider the economic impact on health and social welfare systems. Such evaluations can provide the data needed to guide evidence-informed decision-making that can contribute to safer implementation and refinement of MAiD MI-SUMC.","PeriodicalId":9259,"journal":{"name":"British Journal of Psychiatry","volume":" ","pages":"264-267"},"PeriodicalIF":8.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140020966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

All psychiatric disorders are equal, but some are more equal than others! An unconscious bias that calls for precision terminology. 所有精神疾病都是平等的，但有些疾病比其他疾病更平等！无意识的偏见需要精确的术语。

IF 8.7 1区医学

British Journal of Psychiatry Pub Date : 2024-07-01 Epub Date: 2024-09-02 DOI: 10.1192/bjp.2024.8

Shokouh Arjmand, Matti Bock Guldager, Gregers Wegener

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General psychiatry, still in no-man's land after all these years: commentary, Pelosi. 普通精神病学，这么多年来仍处于无人区：评论，佩洛西。

IF 8.7 1区医学

British Journal of Psychiatry Pub Date : 2024-07-01 Epub Date: 2024-09-02 DOI: 10.1192/bjp.2024.38

Anthony Pelosi

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Queen Charlotte (and 'the mad king'): where lived experience is more important than diagnosis - Psychiatry in television. 夏洛特女王（和 "疯王"）：生活经历比诊断更重要--电视精神病学。

IF 8.7 1区医学

British Journal of Psychiatry Pub Date : 2024-07-01 Epub Date: 2024-09-02 DOI: 10.1192/bjp.2024.29

Harry Barker, Paul O Wilkinson

引用次数: 0

General psychiatry, still in no-man's land after all these years: commentary, Deahl. 普通精神病学，多年后仍处于无人区：评论，Deahl。

IF 8.7 1区医学

British Journal of Psychiatry Pub Date : 2024-07-01 Epub Date: 2024-09-02 DOI: 10.1192/bjp.2024.55

Martin Deahl

引用次数: 0

Predicting patients with dementia most at risk of needing psychiatric in-patient or enhanced community care using routinely collected clinical data: retrospective multi-site cohort study. 利用常规收集的临床数据预测最有可能需要精神科住院治疗或加强社区护理的痴呆症患者：回顾性多地点队列研究。

IF 10.5 1区医学

British Journal of Psychiatry Pub Date : 2024-06-01 DOI: 10.1192/bjp.2024.14

Sabina R London, Shanquan Chen, Emad Sidhom, Jonathan R Lewis, Emma Wolverson, Rudolf N Cardinal, David Roalf, Christoph Mueller, Benjamin R Underwood

{"title":"Predicting patients with dementia most at risk of needing psychiatric in-patient or enhanced community care using routinely collected clinical data: retrospective multi-site cohort study.","authors":"Sabina R London, Shanquan Chen, Emad Sidhom, Jonathan R Lewis, Emma Wolverson, Rudolf N Cardinal, David Roalf, Christoph Mueller, Benjamin R Underwood","doi":"10.1192/bjp.2024.14","DOIUrl":"10.1192/bjp.2024.14","url":null,"abstract":"Background: Dementia is a common and progressive condition whose prevalence is growing worldwide. It is challenging for healthcare systems to provide continuity in clinical services for all patients from diagnosis to death.Aims: To test whether individuals who are most likely to need enhanced care later in the disease course can be identified at the point of diagnosis, thus allowing the targeted intervention.Method: We used clinical information collected routinely in de-identified electronic patient records from two UK National Health Service (NHS) trusts to identify at diagnosis which individuals were at increased risk of needing enhanced care (psychiatric in-patient or intensive (crisis) community care).Results: We examined the records of a total of 25 326 patients with dementia. A minority (16% in the Cambridgeshire trust and 2.4% in the London trust) needed enhanced care. Patients who needed enhanced care differed from those who did not in age, cognitive test scores and Health of the Nation Outcome Scale scores. Logistic regression discriminated risk, with an area under the receiver operating characteristic curve (AUROC) of up to 0.78 after 1 year and 0.74 after 4 years. We were able to confirm the validity of the approach in two trusts that differed widely in the populations they serve.Conclusions: It is possible to identify, at the time of diagnosis of dementia, individuals most likely to need enhanced care later in the disease course. This permits the development of targeted clinical interventions for this high-risk group.","PeriodicalId":9259,"journal":{"name":"British Journal of Psychiatry","volume":" ","pages":"221-229"},"PeriodicalIF":10.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140911413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Estimating demand for potential disease-modifying therapies for Alzheimer's disease in the UK. 估算英国对阿尔茨海默病潜在疾病改变疗法的需求。

IF 8.7 1区医学

British Journal of Psychiatry Pub Date : 2024-06-01 DOI: 10.1192/bjp.2023.166

Axel A S Laurell, Ashwin V Venkataraman, Tatjana Schmidt, Marcella Montagnese, Christoph Mueller, Robert Stewart, Jonathan Lewis, Clare Mundell, Jeremy D Isaacs, Mani S Krishnan, Robert Barber, Timothy Rittman, Benjamin R Underwood

{"title":"Estimating demand for potential disease-modifying therapies for Alzheimer's disease in the UK.","authors":"Axel A S Laurell, Ashwin V Venkataraman, Tatjana Schmidt, Marcella Montagnese, Christoph Mueller, Robert Stewart, Jonathan Lewis, Clare Mundell, Jeremy D Isaacs, Mani S Krishnan, Robert Barber, Timothy Rittman, Benjamin R Underwood","doi":"10.1192/bjp.2023.166","DOIUrl":"10.1192/bjp.2023.166","url":null,"abstract":"Background: Phase three trials of the monoclonal antibodies lecanemab and donanemab, which target brain amyloid, have reported statistically significant differences in clinical end-points in early Alzheimer's disease. These drugs are already in use in some countries and are going through the regulatory approval process for use in the UK. Concerns have been raised about the ability of healthcare systems, including those in the UK, to deliver these treatments, considering the resources required for their administration and monitoring.Aims: To estimate the scale of real-world demand for monoclonal antibodies for Alzheimer's disease in the UK.Method: We used anonymised patient record databases from two National Health Service trusts for the year 2019 to collect clinical, demographic, cognitive and neuroimaging data for these cohorts. Eligibility for treatment was assessed using the inclusion criteria from the clinical trials of donanemab and lecanemab, with consideration given to diagnosis, cognitive performance, cerebrovascular disease and willingness to receive treatment.Results: We examined the records of 82 386 people referred to services covering around 2.2 million people. After applying the trial criteria, we estimate that a maximum of 906 people per year would start treatment with monoclonal antibodies in the two services, equating to 30 200 people if extrapolated nationally.Conclusions: Monoclonal antibody treatments for Alzheimer's disease are likely to present a significant challenge for healthcare services to deliver in terms of the neuroimaging and treatment delivery. The data provided here allows health services to understand the potential demand and plan accordingly.","PeriodicalId":9259,"journal":{"name":"British Journal of Psychiatry","volume":" ","pages":"198-204"},"PeriodicalIF":8.7,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139485145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0