Advances in bioscience and clinical medicine最新文献_第3页

Sciatica Reveling Thigh Hydatidosis 坐骨神经痛

Advances in bioscience and clinical medicine Pub Date : 2021-10-31 DOI: 10.7575/aiac.abcmed.v.9n.4p.47

M. Iken, M. Boussaidane, Badr Lmimouni1, M. Boussouga

引用次数: 0

Prospective Study of Food Chain Mold Contamination in Rabat City 拉巴特市食物链霉菌污染的前瞻性研究

Advances in bioscience and clinical medicine Pub Date : 2021-10-31 DOI: 10.7575/aiac.abcmed.v.9n.4p.6

M. Iken, Noufissa Aloui, Leila Boumhil, H. Naoui, B. Lmimouni

{"title":"Prospective Study of Food Chain Mold Contamination in Rabat City","authors":"M. Iken, Noufissa Aloui, Leila Boumhil, H. Naoui, B. Lmimouni","doi":"10.7575/aiac.abcmed.v.9n.4p.6","DOIUrl":"https://doi.org/10.7575/aiac.abcmed.v.9n.4p.6","url":null,"abstract":"Introduction: Contamination by molds is a major public health problem and a real danger for both humans and animals due to the synthesis of toxic metabolites (Mycotoxins) during their proliferation in foods of plant or animal origin.Their effects on health are very harmful and can go as far as death in the event of heavy contamination. Prolonged exposure to low doses can cause several pathologies including nephropathies, cancers, liver damage, hemorrhagic syndromes, and immunological and neurological disorders. Material, Methods and Results: In this work, the contamination of Moroccan foodstuffs with mycotoxins was studied. A total of 22 samples: 13 samples of spices, 7 samples of coffee, 1 sample of tea and 1 sample of chocolate, were purchased from different popular markets of Rabat. Mycological study of 22 of these samples showed a large number of fungal contaminants resulting in a 100% contamination of all our samples Among them, it indicates the presence of the principal genus implicated in the production of mycotoxins: Aspergillus spp (77% Penicillium spp (18%), and Mucor (90%). Detection of mycotoxins is performed by LC-MSMS. The results showed a variation in levelsof aflatoxin B1 and ochratoxin A, without exceeding the maximum limits set by Moroccan regulations. Conclusion: The prevention of contamination of raw materials and the development of molds implies respect for good farming practices and storage conditions for food products. Risk management is the responsibility of governments and require total respect of international recommendations to reduce the impact on the economy and health population.","PeriodicalId":92322,"journal":{"name":"Advances in bioscience and clinical medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44166705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sonographic Assessment of Fetal Cephalic Index in a Sampled Nigerian Population 尼日利亚抽样人群胎儿头部指数的声像图评估

Advances in bioscience and clinical medicine Pub Date : 2021-10-31 DOI: 10.7575/aiac.abcmed.v.9n.4p.1

A. Erim, Wueseter A. Ijever, Itoro Efanga, B. Udoh

{"title":"Sonographic Assessment of Fetal Cephalic Index in a Sampled Nigerian Population","authors":"A. Erim, Wueseter A. Ijever, Itoro Efanga, B. Udoh","doi":"10.7575/aiac.abcmed.v.9n.4p.1","DOIUrl":"https://doi.org/10.7575/aiac.abcmed.v.9n.4p.1","url":null,"abstract":"Objectives: The study aimed to determine fetal cephalic index among fetuses in Cross River State, Nigeria. Materials and Method: Transabdominal ultrasound was carried out on 220 women attending obstetric sonography in their second and third trimesters between September and December, 2020 in Cross River State, Nigeria. Each patient was scanned in a supine position, Bi-parietal diameter (BPD) measurements were taken from the outer edge of the closer temporoparietal bone to the inner edge of the farther temporoparietal bone. The occipito-frontal (OF) measurements were taken from the occipital bone to the frontal bone, and the cephalic index determined using the formula CI = BPD/OF *100. Results: Mean values of cephalic index and standard deviation was calculated for the fetuses at different gestational ages. The results showed that the mean cephalic index was 76.48±11.87. Male fetuses had cephalic index of 78.18±4.11 while female had cephalic index of 74.34±16.52. There was significant difference in the cephalic index between male and female fetuses (p<0.002). Conclusion: The present study shows the cephalic index of fetuses of cross river state population remained mesaticephalic from 13 weeks of gestation to full term. This may be attributed to the ethnicity and race of this group of people.","PeriodicalId":92322,"journal":{"name":"Advances in bioscience and clinical medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49516972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification and Validation of a Prognostic Biomarker for Septic Arthritis: A Hypothesis 鉴定和验证化脓性关节炎的预后生物标志物:一个假设

Advances in bioscience and clinical medicine Pub Date : 2021-10-31 DOI: 10.7575/aiac.abcmed.v.9n.4p.41

Ravi Adusumalli, S. Sreenivasa

{"title":"Identification and Validation of a Prognostic Biomarker for Septic Arthritis: A Hypothesis","authors":"Ravi Adusumalli, S. Sreenivasa","doi":"10.7575/aiac.abcmed.v.9n.4p.41","DOIUrl":"https://doi.org/10.7575/aiac.abcmed.v.9n.4p.41","url":null,"abstract":"Inflammation is a hallmark of many diseases including septic arthritis (SA) or infectious arthritis (IA). The bacteria Staphylococcus aureus is the most common cause of septic arthritis in humans. The statistical incident rate for SA is 2-10 per 100,000 patients years in the USA and Western Europe. Currently, there is no ideal diagnostic or prognostic biomarker for SA at the moment. By virtue of their lack of specificity and accuracy, traditional inflammatory biomarkers are often ineffective in distinguishing SA from infectious joint disease. The present hypothesis wishes to explore the discriminatory power of unique inflammatory biomarkers in liquid biopsy samples of bacteria induced mice and SA patient samples by means of genome wide analysis in which includes epigenetic, genomics and transcriptome expression pattern. Investigation on gene expression by RNA sequencing and DNA methylation studies provides the best possible target genes of differentially expressed both RNA and DNA marker genes. The aim is to find a meaningful positive or negative association between gene expression in RNA sequencing data and DNA methylation status. Validation of differentially expressed genes and differentially methylated genes by functional mechanistic studies to determine the best predictive and prognostic marker for SA for regular therapeutic use by comparison with established reference genes. With respect to bacterial mediated mice vs SA patient gene contrast, the predicted results clarifies the in-depth understanding of pathophysiology, disease development, and SA status.","PeriodicalId":92322,"journal":{"name":"Advances in bioscience and clinical medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45379784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19 Drugs and Glucose-6-phosphate Dehydrogenase Deficiency: A Matter of Life Threatening And Public Health COVID-19药物和葡萄糖-6-磷酸脱氢酶缺乏症:威胁生命和公共卫生的问题

Advances in bioscience and clinical medicine Pub Date : 2021-10-31 DOI: 10.7575/aiac.abcmed.v.9n.4p.24

Carmela Ioscoa, Verity Eason, Ibrahima Gueyec, Renee Leavy

{"title":"COVID-19 Drugs and Glucose-6-phosphate Dehydrogenase Deficiency: A Matter of Life Threatening And Public Health","authors":"Carmela Ioscoa, Verity Eason, Ibrahima Gueyec, Renee Leavy","doi":"10.7575/aiac.abcmed.v.9n.4p.24","DOIUrl":"https://doi.org/10.7575/aiac.abcmed.v.9n.4p.24","url":null,"abstract":"Background: The current COVID-19 pandemic has created significant health consequences for the world population. Therapies and drugs are being continuously developed in an effort to implement the most effective treatment. G6PD deficiency is the most prevalent human enzymatic defect, affecting more than 500 million people worldwide, but is infrequently taken into consideration in healthcare practice. Purpose: The aim of this review is collecting and assembling the most relevant information about safety of current drugs and nutraceuticals, proposed or already used for COVID-19 treatment, with regard to G6PD deficient people, in order to know possible drug-induced adverse effects. Methods: An extensive literature search was performed through scientific papers, unsafe drug lists, drug datasheets, drug databases, National Public Health institutional websites. Results: Methylene blue, ozone, chloroquine and hydroxychloroquine administration should be avoided in G6PD deficient patients. The other reviewed drugs should be administered at therapeutic doses under medical supervision. Conclusion: The list of drugs and nutraceuticals for use in COVID-19 here provided, usefully brought to Healthcare personnel’s and patients’ awareness before any drug administration, may allow you to avoid or at least manage any possible drug-associated symptoms - particularly hemolytic crisis, which is a potentially fatal risk for G6PD deficient patients.","PeriodicalId":92322,"journal":{"name":"Advances in bioscience and clinical medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41580916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Causes and Consequences of Nuclear Envelope Rupture and DNA Damage in Micronuclei 微核中核膜破裂和DNA损伤的原因和后果

Advances in bioscience and clinical medicine Pub Date : 2021-10-31 DOI: 10.7575/aiac.abcmed.v.9n.4p.12

Ania Grodsky

引用次数: 0

Hormonal Replacement Therapy in Surgically Induced Menopause: A Prospective Cross Section Study from a Tertiary Care Institution from A Sub-himalayan State 激素替代疗法治疗外科诱导的更年期：来自亚喜马拉雅州一家三级护理机构的前瞻性横断面研究

Advances in bioscience and clinical medicine Pub Date : 2021-07-31 DOI: 10.7575/aiac.abcmed.v.9n.3p.10

Jatinder Kumar Mokta, Kiran Kumar Mokta, Arjun Tandon, Renuka Pathania, A. Sharma, M. Raj, Akshit Negi, Arnav Mokta, -. Ramesh

引用次数: 0

Obstructing Trachea Tumor: Myoepithelial Carcinoma about a Case 梗阻性气管肿瘤:肌上皮癌1例

Advances in bioscience and clinical medicine Pub Date : 2021-07-30 DOI: 10.7575/aiac.abcmed.v.9n.3p.45

A. Kessab, A. Zegmout, Mohammed Reda El Ochi, Wafaa El Omari, Abderrahmane Rhorfi, M. Oukabli

引用次数: 0

Study of the Effect of Health System Reform Plan Administration on the Satisfaction Level among Medical Doctors and Nurses in Tabriz State Hospitals, East Azerbaijan, Iran 卫生体制改革计划管理对伊朗东阿塞拜疆大不里士国立医院医护人员满意度的影响研究

Advances in bioscience and clinical medicine Pub Date : 2021-07-29 DOI: 10.7575/aiac.abcmed.v.9n.3p.21

S. Jodi, H. Mahmoudi, Vahid Majidi

{"title":"Study of the Effect of Health System Reform Plan Administration on the Satisfaction Level among Medical Doctors and Nurses in Tabriz State Hospitals, East Azerbaijan, Iran","authors":"S. Jodi, H. Mahmoudi, Vahid Majidi","doi":"10.7575/aiac.abcmed.v.9n.3p.21","DOIUrl":"https://doi.org/10.7575/aiac.abcmed.v.9n.3p.21","url":null,"abstract":"Having three orientations, the Health System Reform Plan (HSRP) has been administered to financially support and protect people, provide fair health services and promote the quality of health services. To be unsatisfied about health and medical services brings undesirable outcomes. The present investigation aimed to study the effect of Health System Reform Plan (HSRP) on the satisfaction level among medical doctors and nurses of Tabriz state hospitals, East Azerbaijan province, Iran in a period from 21th February; 2015 to 22th June; 2015. Statistical population included those patients who referred to Tabriz state hospitals. We used stratified sampling method. To collect data we used questionnaire being presented to the samples after assessing its validity and reliability. We also utilized descriptive and inferential statistics in a way that we used descriptive method to classify, summarize and interpret of obtained data. Then after demonstrating the abnormality of data by Kolmogorov-Smirnov test we used linear and multiple regressions to test research hypothesis and effect from the perspective of inferential method. Obtained results confirmed the research hypothesis and explained that the administration of HSRP affected medical doctors’ level of satisfaction. Also, according to the results of multiple regression tests, doctors and nurses’ satisfaction level was placed at the top of most affected issues from HSRP.","PeriodicalId":92322,"journal":{"name":"Advances in bioscience and clinical medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43394572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Model Organisms in Cancer Research-Powers and Limitations 癌症研究中的模式生物——权力与局限

Advances in bioscience and clinical medicine Pub Date : 2021-04-30 DOI: 10.7575/AIAC.ABCMED.V.9N.2P.1

Ravi Adusumalli

{"title":"Model Organisms in Cancer Research-Powers and Limitations","authors":"Ravi Adusumalli","doi":"10.7575/AIAC.ABCMED.V.9N.2P.1","DOIUrl":"https://doi.org/10.7575/AIAC.ABCMED.V.9N.2P.1","url":null,"abstract":"Background: Cancer is a term that is used to describe a wide range of diseases, but they all have some characteristics in common. The goal of this review is to highlight the most commonly used cancer models as well as their role in tumor biology. Although each model has inherent powers and limitations in faithfully mirroring the complexity of tumorigenesis, there is no perfect single model for cancer. Main body: Oncologists can learn about the tumor microenvironment, gene mutations, and complex physiological systems using model organisms for cancer research. The widespread use of model organisms in cancer research has greatly improved understanding of how mutations in humans lead to cancer. Human cancer cell lines, drosophila, yeast, and mice are among the model organisms used to study cancer. However, these model organisms have flaws that can cause the tumor microenvironment to be falsified and restrict the defined targets in translational studies. Conclusion: The overwhelming message from various animal models allows us to better understand the state of the disease and develop new cancer treatments. Mice are a good substitute and surrogate for patients in the evaluation of diagnosis and prognosis among the various model organisms used in cancer research.","PeriodicalId":92322,"journal":{"name":"Advances in bioscience and clinical medicine","volume":"9 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2021-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46745506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0