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Abstract PO-118: The tumor immune microenvironment is decisive in the survival of pancreatic ductal adenocarcinoma 摘要PO-118:肿瘤免疫微环境在胰腺导管腺癌的生存中起决定性作用
Tumor & microenvironment Pub Date : 2021-11-15 DOI: 10.1158/1538-7445.panca21-po-118
Hosein M. Aziz, Lawlaw Saida, W. de Koning, A. Stubbs, Yunlei Li, C. V. van Eijck, D. Mustafa
{"title":"Abstract PO-118: The tumor immune microenvironment is decisive in the survival of pancreatic ductal adenocarcinoma","authors":"Hosein M. Aziz, Lawlaw Saida, W. de Koning, A. Stubbs, Yunlei Li, C. V. van Eijck, D. Mustafa","doi":"10.1158/1538-7445.panca21-po-118","DOIUrl":"https://doi.org/10.1158/1538-7445.panca21-po-118","url":null,"abstract":"","PeriodicalId":92311,"journal":{"name":"Tumor & microenvironment","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76999963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract PO-101: Characterization of longitudinally collected fine needle aspiration biopsies of pancreatic ductal adenocarcinoma upon endoscopic ultrasound guided radiofrequency ablation PO-101:超声内镜引导下射频消融下纵向收集胰腺导管腺癌细针穿刺活检的特点
Tumor & microenvironment Pub Date : 2021-11-15 DOI: 10.1158/1538-7445.panca21-po-101
Krisha Desai, Patrick Varun Lawrence, C. Wadsworth, N. Mangal, N. Habib, A. Sadanandam, M. Sodergren
{"title":"Abstract PO-101: Characterization of longitudinally collected fine needle aspiration biopsies of pancreatic ductal adenocarcinoma upon endoscopic ultrasound guided radiofrequency ablation","authors":"Krisha Desai, Patrick Varun Lawrence, C. Wadsworth, N. Mangal, N. Habib, A. Sadanandam, M. Sodergren","doi":"10.1158/1538-7445.panca21-po-101","DOIUrl":"https://doi.org/10.1158/1538-7445.panca21-po-101","url":null,"abstract":"","PeriodicalId":92311,"journal":{"name":"Tumor & microenvironment","volume":"263 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85863400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract PO-102: Fibroblast-derived interleukin-33 promotes pancreatic ductal adenocarcinoma as a result of tumor cell KRASG12D PO-102:成纤维细胞来源的白介素-33通过肿瘤细胞KRASG12D促进胰腺导管腺癌
Tumor & microenvironment Pub Date : 2021-11-15 DOI: 10.1158/1538-7445.panca21-po-102
Katelyn L. Donahue, Wenting Du, Carlos E Espinoza, Eileen S Carpenter, Kristee L Brown, N. Steele, M. Pasca di Magliano
{"title":"Abstract PO-102: Fibroblast-derived interleukin-33 promotes pancreatic ductal adenocarcinoma as a result of tumor cell KRASG12D","authors":"Katelyn L. Donahue, Wenting Du, Carlos E Espinoza, Eileen S Carpenter, Kristee L Brown, N. Steele, M. Pasca di Magliano","doi":"10.1158/1538-7445.panca21-po-102","DOIUrl":"https://doi.org/10.1158/1538-7445.panca21-po-102","url":null,"abstract":"","PeriodicalId":92311,"journal":{"name":"Tumor & microenvironment","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88738195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract PO-129: Targeting CCR1 reprograms tumor associated macrophages in pancreatic cancer PO-129:靶向CCR1在胰腺癌中重编程肿瘤相关巨噬细胞
Tumor & microenvironment Pub Date : 2021-11-15 DOI: 10.1158/1538-7445.panca21-po-129
Yaqing Zhang, Kristee L Brown, Wei Yan, Z. Nwosu, Eileen Carpenter, Katelyn L. Donahue, Ashley Velez-Delgado, Sion Yang, M. Pasca di Magliano
{"title":"Abstract PO-129: Targeting CCR1 reprograms tumor associated macrophages in pancreatic cancer","authors":"Yaqing Zhang, Kristee L Brown, Wei Yan, Z. Nwosu, Eileen Carpenter, Katelyn L. Donahue, Ashley Velez-Delgado, Sion Yang, M. Pasca di Magliano","doi":"10.1158/1538-7445.panca21-po-129","DOIUrl":"https://doi.org/10.1158/1538-7445.panca21-po-129","url":null,"abstract":"","PeriodicalId":92311,"journal":{"name":"Tumor & microenvironment","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84098146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract PR-014: Hedgehog represses angiogenesis in PDAC through a paracrine cascade mediated by Wif1 PR-014: Hedgehog基因通过wip1介导的旁分泌级联抑制PDAC中的血管生成
Tumor & microenvironment Pub Date : 2021-11-15 DOI: 10.1158/1538-7445.panca21-pr-014
Marie C. Hasselluhn, Amanda R. Decker, Álvaro Curiel García, Carlo Maurer, Dafydd H. Thomas, K. Olive
{"title":"Abstract PR-014: Hedgehog represses angiogenesis in PDAC through a paracrine cascade mediated by Wif1","authors":"Marie C. Hasselluhn, Amanda R. Decker, Álvaro Curiel García, Carlo Maurer, Dafydd H. Thomas, K. Olive","doi":"10.1158/1538-7445.panca21-pr-014","DOIUrl":"https://doi.org/10.1158/1538-7445.panca21-pr-014","url":null,"abstract":"","PeriodicalId":92311,"journal":{"name":"Tumor & microenvironment","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84331405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract PO-119: DFMO mediated improvement in survival of an orthotopic model of pancreatic cancer is associated with modulating immune suppression in the tumor microenvironment PO-119: DFMO介导的胰腺癌原位模型生存改善与调节肿瘤微环境中的免疫抑制有关
Tumor & microenvironment Pub Date : 2021-11-15 DOI: 10.1158/1538-7445.panca21-po-119
Sai Preethi Nakkina, Sarah B Gitto, Veethika Pandey, Jordan M. Beardsley, Michael W Rohr, J. Parikh, O. Phanstiel, D. Altomare
{"title":"Abstract PO-119: DFMO mediated improvement in survival of an orthotopic model of pancreatic cancer is associated with modulating immune suppression in the tumor microenvironment","authors":"Sai Preethi Nakkina, Sarah B Gitto, Veethika Pandey, Jordan M. Beardsley, Michael W Rohr, J. Parikh, O. Phanstiel, D. Altomare","doi":"10.1158/1538-7445.panca21-po-119","DOIUrl":"https://doi.org/10.1158/1538-7445.panca21-po-119","url":null,"abstract":"","PeriodicalId":92311,"journal":{"name":"Tumor & microenvironment","volume":"355 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89291181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract PO-098: Longitudinal profiling of pancreatic cancer patients identifies interleukin-8 as a mediator of myeloid-epithelial crosstalk PO-098:胰腺癌患者的纵向分析确定白细胞介素-8是骨髓-上皮串扰的中介
Tumor & microenvironment Pub Date : 2021-11-15 DOI: 10.1158/1538-7445.panca21-po-098
Eileen S Carpenter, Samantha B. Kemp, Padma Kadiyala, N. Steele, Ahmed M Elhossiny, S. The, Valerie Gunchick, R. Nicolle, Michelle A Anderson, Wenting Du, Carlos E Espinoza, Richard S. Kwon, Erik-Jan Wamsteker, A. Prabhu, Allison Schulman, V. Sahai, T. Frankel, Filip Bednar, M. Pasca di Magliano
{"title":"Abstract PO-098: Longitudinal profiling of pancreatic cancer patients identifies interleukin-8 as a mediator of myeloid-epithelial crosstalk","authors":"Eileen S Carpenter, Samantha B. Kemp, Padma Kadiyala, N. Steele, Ahmed M Elhossiny, S. The, Valerie Gunchick, R. Nicolle, Michelle A Anderson, Wenting Du, Carlos E Espinoza, Richard S. Kwon, Erik-Jan Wamsteker, A. Prabhu, Allison Schulman, V. Sahai, T. Frankel, Filip Bednar, M. Pasca di Magliano","doi":"10.1158/1538-7445.panca21-po-098","DOIUrl":"https://doi.org/10.1158/1538-7445.panca21-po-098","url":null,"abstract":"","PeriodicalId":92311,"journal":{"name":"Tumor & microenvironment","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86125657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract PO-105: Overcoming stromal barriers in PDA with a novel polymeric Toll-like receptor agonist PO-105:一种新型聚合物toll样受体激动剂克服PDA的间质屏障
Tumor & microenvironment Pub Date : 2021-11-15 DOI: 10.1158/1538-7445.panca21-po-105
Christopher C DuFort, Ciana L López, Martin C. Whittle, Vladimir A Vlaskin, A. Vadodkar, Selvi Srinivasan, P. Stayton, S. Hingorani
{"title":"Abstract PO-105: Overcoming stromal barriers in PDA with a novel polymeric Toll-like receptor agonist","authors":"Christopher C DuFort, Ciana L López, Martin C. Whittle, Vladimir A Vlaskin, A. Vadodkar, Selvi Srinivasan, P. Stayton, S. Hingorani","doi":"10.1158/1538-7445.panca21-po-105","DOIUrl":"https://doi.org/10.1158/1538-7445.panca21-po-105","url":null,"abstract":"","PeriodicalId":92311,"journal":{"name":"Tumor & microenvironment","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73174956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract PR-016: Extrinsic KRAS signaling shapes the pancreatic microenvironment through fibroblast reprogramming PR-016:外源性KRAS信号通过成纤维细胞重编程塑造胰腺微环境
Tumor & microenvironment Pub Date : 2021-11-15 DOI: 10.1158/1538-7445.panca21-pr-016
Ashley Velez-Delgado, Katelyn L. Donahue, Kristee L Brown, Wenting Du, Valerie Irizarry-Negron, Rosa E. Menjivar, Emily L. Lasse-Opsahl, N. Steele, S. The, J. Lazarus, Veerin R. Sirihorachai, Filip Bednar, T. Frankel, Yaqing Zhang, M. Pasca di Magliano
{"title":"Abstract PR-016: Extrinsic KRAS signaling shapes the pancreatic microenvironment through fibroblast reprogramming","authors":"Ashley Velez-Delgado, Katelyn L. Donahue, Kristee L Brown, Wenting Du, Valerie Irizarry-Negron, Rosa E. Menjivar, Emily L. Lasse-Opsahl, N. Steele, S. The, J. Lazarus, Veerin R. Sirihorachai, Filip Bednar, T. Frankel, Yaqing Zhang, M. Pasca di Magliano","doi":"10.1158/1538-7445.panca21-pr-016","DOIUrl":"https://doi.org/10.1158/1538-7445.panca21-pr-016","url":null,"abstract":"","PeriodicalId":92311,"journal":{"name":"Tumor & microenvironment","volume":"40 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72541284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
Abstract PR-013: The splanchnic mesenchyme during fetal development is the major source of pancreatic cancer associated fibroblasts 摘要PR-013:胎儿发育过程中的内脏间质是胰腺癌相关成纤维细胞的主要来源
Tumor & microenvironment Pub Date : 2021-11-15 DOI: 10.1158/1538-7445.panca21-pr-013
Lu Han, Yongxia Wu, Melodie Parrish, Khushbu R Patel, Xuezhong Yu, Michael C Ostrowski, G. Leone
{"title":"Abstract PR-013: The splanchnic mesenchyme during fetal development is the major source of pancreatic cancer associated fibroblasts","authors":"Lu Han, Yongxia Wu, Melodie Parrish, Khushbu R Patel, Xuezhong Yu, Michael C Ostrowski, G. Leone","doi":"10.1158/1538-7445.panca21-pr-013","DOIUrl":"https://doi.org/10.1158/1538-7445.panca21-pr-013","url":null,"abstract":"","PeriodicalId":92311,"journal":{"name":"Tumor & microenvironment","volume":"175 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72694232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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