International journal of women's health and wellness最新文献_第5页

Histological Modifications of Postmenopausal Vaginal Mucosa after Regenerative Solid State Laser Treatment: A Multicenter Study 再生固体激光治疗后绝经后阴道黏膜的组织学改变:一项多中心研究

International journal of women's health and wellness Pub Date : 2019-07-17 DOI: 10.23937/2474-1353/1510099

Dodero D, Frascani F, Angelucci M, Bernabei G, Merlo E, Locatelli F, Recalcati D, Murina F

{"title":"Histological Modifications of Postmenopausal Vaginal Mucosa after Regenerative Solid State Laser Treatment: A Multicenter Study","authors":"Dodero D, Frascani F, Angelucci M, Bernabei G, Merlo E, Locatelli F, Recalcati D, Murina F","doi":"10.23937/2474-1353/1510099","DOIUrl":"https://doi.org/10.23937/2474-1353/1510099","url":null,"abstract":"Background: Vulvovaginal atrophy (VVA) is a condition afflicting more than 50% of women and nowadays has changed his name in Genitourinary syndrome of menopause (GSM) due to the multiple aspects involved having an adverse impact on quality of life. Many treatment are now available and laser represent a new powerful option. The aim of this work is assess the histological effect of a new type of non-ablative laser, Solid State Vaginal Laser (SSVL), on vaginal tissue in women treated for GSM. Method: Eighty participants with GSM symptoms were treated with a total of 4 treatments in a two months timeframe (every 15-20 day) of a non-ablative SSVL (LASEmaR 1500TM EUFOTON). Vaginal biopic samples were collected before the start of the first treatment and after 4 weeks from the last one and an analysis of histological characteristics was conducted. A cumulative intensity of GSM symptoms using a 10-cm VAS (dryness and/or burning and/or dyspareunia), the vaginal health index (VHI), the Female Sexual Function Index (FSFI) and Urinary Incontinence Short Form (ICIQ-UI SF) were also evaluated. Results: Improvement in vaginal histological parameters for atrophy was demonstrated following the SSVL treatment. Amelioration was observed in order of thickening of the derma surface, phenomenon of glycogenic acanthosis, increased number and highness of papillae in chorion and in term of reduction in the inflammatory tissue infiltrate. Was also observed on VHIS, VVA symptoms and sexual female function. Conclusion: The evaluation of histological results indicates a favorable effect of SSVL on vaginal atrophy in GSM in terms of epithelium restauration as well as on inflammatory infiltration of the tissue.","PeriodicalId":92223,"journal":{"name":"International journal of women's health and wellness","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85905028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Level of Maternal Satisfaction and its Determinants at Health Facilities in Mizan-Aman Town, Ethiopia: Cross Sectional Study 埃塞俄比亚米赞-阿曼镇卫生设施产妇满意度及其决定因素水平:横断面研究

International journal of women's health and wellness Pub Date : 2019-06-30 DOI: 10.23937/2474-1353/1510088

Yarinbab Teklemariam Ergat, Ambo Wasihun Adraro, Regea Tariku, mariam Addisu

引用次数: 9

Development of In Vitro Fertilization, a Very Important Part of Human Reproductive Medicine, in the Last 40 Years 体外受精是人类生殖医学的重要组成部分，近40年来的发展

International journal of women's health and wellness Pub Date : 2019-06-30 DOI: 10.23937/2474-1353/1510089

Reigstad Marte Myhre, Storeng Ritsa

引用次数: 6

Triple-Negative Breast Cancer: What Crucial Information can Imaging Add to the Diagnosis, Treatment and Prognosis? 三阴性乳腺癌:影像对诊断、治疗和预后有哪些重要作用?

International journal of women's health and wellness Pub Date : 2019-06-30 DOI: 10.23937/2474-1353/1510087

McGarry William M, Bhole Sonya

{"title":"Triple-Negative Breast Cancer: What Crucial Information can Imaging Add to the Diagnosis, Treatment and Prognosis?","authors":"McGarry William M, Bhole Sonya","doi":"10.23937/2474-1353/1510087","DOIUrl":"https://doi.org/10.23937/2474-1353/1510087","url":null,"abstract":"Breast cancer is a heterogeneous disease, with many distinct subtypes having extremely different presentations, biological aggressiveness, and response to therapy. Triplenegative breast cancer is a subtype with significant clinical implications because of its poor prognosis and aggressive behavior. It has distinct imaging features, often presenting as a mass with typically benign features on mammography and ultrasound and more suspicious findings on magnetic resonance imaging. Triple-negative breast cancer also has unique treatment limitations, with these cancers lacking molecular therapeutic targets expressed by other breast cancer subtypes. Fortunately, Triple-negative breast cancer is very responsive to neoadjuvant chemotherapy, which is the mainstay of treatment for these patients. Patients with triple-negative breast cancer are more likely to achieve pathologic complete remission, which is associated with improved survival. Despite this, patients with triple-negative breast cancer have an overall poorer prognosis compared to other subtypes, especially in the first few years after diagnosis. As this subtype accounts for up to one-fifth of all breast cancer cases, a thorough understanding of the unique imaging features of triple-negative breast cancer, as well as the role of imaging in predicting response to therapy and long term patient prognosis, will allow all involved clinicians to more effectively care for these patients.","PeriodicalId":92223,"journal":{"name":"International journal of women's health and wellness","volume":"65 9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77879250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Fast Track Colorectal Surgery for Deep Endometriosis: A Prospective Randomized Trial 快速结直肠手术治疗深部子宫内膜异位症:一项前瞻性随机试验

International journal of women's health and wellness Pub Date : 2019-06-01 DOI: 10.23937/2474-1353/1510097

I. Gentile, R. Rossini, M. Scioscia, D. Brunelli, M. Ceccaroni, G. Ruffo

引用次数: 0

Influence of Maternal BMI and Maternal Weight Gain during Pregnancy on Maternal and Perinatal Outcome - A Retrospective Data Analysis of Pregnancies during 2004 and 2014 妊娠期孕产妇体重指数和体重增加对孕产妇和围产期结局的影响——2004年和2014年妊娠的回顾性数据分析

International journal of women's health and wellness Pub Date : 2019-05-06 DOI: 10.23937/2474-1353/1510095

S. Kundu, L. Kaukemueller, C. Kaisenberg, P. Hillemanns, P. Soergel, E. Kuehnle, I. Staboulidou

引用次数: 2

Unmasking Hidden Recurrent Cancers using FMTVDM/BEST: The Fleming Cancer Hypothesis 使用FMTVDM/BEST揭示隐藏的复发性癌症:弗莱明癌症假说

International journal of women's health and wellness Pub Date : 2019-04-24 DOI: 10.23937/2474-1353/1510094

M FlemingRichard, R. Matthew, K ChaudhuriTapan, C DooleyWilliam, McKusick Andrew

引用次数: 1

FMTVDM/BEST Imaging Equally Applicable for Male Breast Cancer FMTVDM/BEST成像同样适用于男性乳腺癌

International journal of women's health and wellness Pub Date : 2019-04-10 DOI: 10.23937/2474-1353/1510093

M FlemingRichard, R. Matthew, K ChaudhuriTapan, C DooleyWilliam, McKusick Andrew

引用次数: 1

FMTVDM/BEST©℗ Imaging for Women with Breast Implants and Dense Breasts FMTVDM/BEST©©Imaging for Women with Breast implant and Dense Breast

International journal of women's health and wellness Pub Date : 2019-04-08 DOI: 10.23937/2474-1353/1510092

M FlemingRichard, R FlemingMatthew, K ChaudhuriTapan, C DooleyWilliam, Kusick Andrew Mc

引用次数: 1

HR-MRI of the Breast at Intervals of Maximum 24 Months: Influence on Tumor Stage at the Time of Diagnosis 间隔最长24个月的乳腺HR-MRI:对诊断时肿瘤分期的影响

International journal of women's health and wellness Pub Date : 2019-04-04 DOI: 10.23937/2474-1353/1510091

Fischer Uwe, M. Hollstein, S. Luftner-Nagel, F. Baum, S. Wienbeck

{"title":"HR-MRI of the Breast at Intervals of Maximum 24 Months: Influence on Tumor Stage at the Time of Diagnosis","authors":"Fischer Uwe, M. Hollstein, S. Luftner-Nagel, F. Baum, S. Wienbeck","doi":"10.23937/2474-1353/1510091","DOIUrl":"https://doi.org/10.23937/2474-1353/1510091","url":null,"abstract":"Purpose: To define the value of repetitive performed exclusive MRI of the breast at intervals of maximum 24 months in asymptomatic women and patients regarding the tumor size and stage at the time of diagnosis. Material and methods: Women with normal MRI of the breast upon initial examination and subsequent breast MRI within intervals of maximum 2 years were included. Benign and malignant lesions as well as the tumor stages were reported and analysed. Results: 8.975 MRI were performed in 2333 women. 6642 exams were subsequent MRI (2.85 follow-up MRI/woman). Within the examination intervals, 290 (4.37% per follow up exam) lesions categorized as MR-BIRADS 4/5 were found in 272 patients. All of these findings were clarified by percutaneous biopsy. Histology revealed benign findings (B1/B2) in 151/290 (52.1%), B3-lesions in 24 (8.3%), and malignant tumors (B5a/B5b) in 115 cases (39.6%). Open biopsy revealed an intraductal carcinoma in 36/115 cases (G1: 11, G2: 16, G3: 9), and an invasive breast cancer in 79/115 cases. Tumor stages of the invasive carcinoma were pT1a (17/79; 21.5%), pT1b (39/79, 49.4%), and pT1c (22/79; 27.8%). Only one invasive cancer was classified as stage pT2. The average size of all invasive tumors was 9.0 mm. Rate of nodal negative invasive cancer was 95.9%. Rate of interval carcinomas was less than 2%. Conclusion: The performance of repetitive MRI of the breast at intervals of maximum 24 months allows the reliable detection of breast cancer at an early stage (pTis, pT1a, pT1b, pN0) with an excellent prognosis.","PeriodicalId":92223,"journal":{"name":"International journal of women's health and wellness","volume":"100 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90065659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3