International clinical pathology journal最新文献_第4页

Prevalence and factors associated with intestinal protozoan and helminthic infections among certified food handlers in Eldoret town, Uasin Gishu county in Kenya 肯尼亚Uasin Gishu县Eldoret镇认证食品加工商肠道原生动物和蠕虫感染的患病率和相关因素

International clinical pathology journal Pub Date : 2018-05-02 DOI: 10.15406/ICPJL.2018.06.00171

J. Ogolla

引用次数: 4

Primary pulmonary MPNST?A rare case report 原发性肺部MPNST?一例罕见病例报告

International clinical pathology journal Pub Date : 2018-04-27 DOI: 10.15406/ICPJL.2018.06.00170

Tazeen Jeelani, Suhail Mushtaq, R. Makhdoomi

{"title":"Primary pulmonary MPNST?A rare case report","authors":"Tazeen Jeelani, Suhail Mushtaq, R. Makhdoomi","doi":"10.15406/ICPJL.2018.06.00170","DOIUrl":"https://doi.org/10.15406/ICPJL.2018.06.00170","url":null,"abstract":"A 60 years old smoker, normotensive, non‒diabetic presented with chief complaints of cough, fever and weight loss for 20 days. On examination the patient was conscious, co‒operative, well oriented, with a respiratory rate of 18/min, blood pressure of 120/70 and pulse rate of 86/min. Cardiovascular and per‒abdomen examination were clinically normal. However, on auscultation decreased breath sounds were found on left lower side of chest. Chest radiograph revealed a lesion in the left lung. CT scan (contrast enhanced) of chest was done which showed a 71x59mm cystic lesion in the superior segment of left lower lobe. Cyst showed internal septations without calcification. USG abdomen and PFT (pulmonary function tests) were normal. Hydrated serology was negative and not suggestive. Routine complete blood counts, LFT (liver function test) and KFT (kidney function tests), were within normal limits. The patient underwent left postero‒lateral thoracotomy with lower lobe lobectomy. Intra‒operatively there was large bronchogenic mass occupying almost whole of the left lobe with multiple hilar nodes. On gross examination, we received a lobe of lung measuring 15x9.5x5cm. Serial slicing of the lung showed a well circumscribed mass measuring 7x8cm. Cut section showed variegated appearance with extensive hemorrhagic and necrotic areas. On light microscopy a spindle cell tumour was seen with cells having moderate to severe pleomorphism and mitosis of >10/10hpf, and extensive areas of necrosis (Figure 1a) (Figure 1b).","PeriodicalId":92215,"journal":{"name":"International clinical pathology journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42749579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extra nodal natural killer lymphoma mimicking canine Fossa infection–a clinical report 模拟犬窝感染的淋巴结外自然杀手淋巴瘤-一份临床报告

International clinical pathology journal Pub Date : 2018-04-13 DOI: 10.15406/ICPJL.2018.06.00168

P. Kumar, V. Dhupar, Francis, Akkara

{"title":"Extra nodal natural killer lymphoma mimicking canine Fossa infection–a clinical report","authors":"P. Kumar, V. Dhupar, Francis, Akkara","doi":"10.15406/ICPJL.2018.06.00168","DOIUrl":"https://doi.org/10.15406/ICPJL.2018.06.00168","url":null,"abstract":"Mature Tor natural killer (NK)/T-cell lymphoma makes up only 5% to 18% of all cases of non-Hodgkin lymphoma (NHL). The relative frequency and optimal therapy for these disorders is not well defined. Extra nodal NK/T-cell lymphoma is a distinct entity in the World Health Organization (WHO) classification [1]. It is more prevalent in Asians and Native Americans, occurs most often in adults, and almost always occurs in extranodal sites with a predilection for the upper airway including nasal passages, paranasal sinuses, and nasopharynx [2,3]. Extranasal sites include skin, soft tissue, and the gastrointestinal tract. Extranodal (NK)/ T-cell lymphoma nasal type is a rare entity with an extremely aggressive nature. We report a unique case of extranodal NK/Tcell lymphoma, nasal type, in a 48-year-old Indian male presenting with progressively increasing hemi facial swelling, periorbital edema and uncontrolled diabetes mellitus mimicking Orofacial infection. Our case demonstrates how the acute presentation of an aggressive extranodal NK/T-cell lymphoma, nasal type, can present in a similar fashion to canine space swelling. Through this report we would like to stress on considering an occult malignancy as differential diagnosis in individuals with altered immune function not responding to conventional treatment and also the role of immuno histochemistry in diagnosing such aggressive tumors.","PeriodicalId":92215,"journal":{"name":"International clinical pathology journal","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41484115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic accuracy of thyroid cytology reporting between a general and a specialist histopathology department, over a five year period 甲状腺细胞学报告的诊断准确性之间的一般和专家组织病理学部门，超过五年的时间

International clinical pathology journal Pub Date : 2018-03-29 DOI: 10.15406/icpjl.2018.06.00167

K. Palial, D. Roskell, G. Wathuge

引用次数: 2

Soft tissue sarcoma, a multidisciplinary team decision: all experts for one correct management 软组织肉瘤，一个多学科团队的决定：所有专家一次正确的管理

International clinical pathology journal Pub Date : 2018-03-22 DOI: 10.15406/icpjl.2018.06.00164

G. Hachem

引用次数: 0

Implications of poor negative predictive values for drugs of abuse screening 不良阴性预测值对药物滥用筛查的影响

International clinical pathology journal Pub Date : 2018-03-22 DOI: 10.15406/icpjl.2018.06.00165

L. Springer

引用次数: 0

Cementoblastoma–a review of literature 成骨细胞瘤——文献综述

International clinical pathology journal Pub Date : 2018-03-22 DOI: 10.15406/ICPJL.2018.06.00166

S. Sayd, Suresh Vyloppilli, K. Gopinath, Ashna Br

引用次数: 2

The grey zone of thrombocytopenia: accuracy of automated analyser vs manual method 血小板减少症的灰色地带:自动分析仪与人工方法的准确性

International clinical pathology journal Pub Date : 2018-03-19 DOI: 10.15406/icpjl.2018.06.00163

G. Gogoi, S. Kar, A. Manta, S. M. Baruah

引用次数: 3

Dysplastic cerebellar gangliocytoma (Lhermite-Duclos disease): a rare entity and review of literature 小脑发育不全神经节细胞瘤（Lhermite-Duclos病）：一种罕见的实体病及文献综述

International clinical pathology journal Pub Date : 2018-03-13 DOI: 10.15406/ICPJL.2018.06.00162

P. Balasundaram, Mallikarjuna Vs, Suresh Kr

引用次数: 0

Is idiopathic pulmonary fibrosis - is environmental or genetic disease - an old wine in a new bottle of treatment 特发性肺纤维化——是环境性疾病还是遗传性疾病——是新疗法中的陈年之酒吗

International clinical pathology journal Pub Date : 2018-03-08 DOI: 10.15406/ICPJL.2018.06.00160

P. Bhattacharya, S. Mukherjee, Upasana Bhattacharya, R. Bhattacharya, Ritwick Bhattacharya, Rupsa Bhattacharya, Dalia Mukherjee, Ayishee Mukherjee, Debasis Mukherjee, H. Banerjee, S. Panda, A. Roy

{"title":"Is idiopathic pulmonary fibrosis - is environmental or genetic disease - an old wine in a new bottle of treatment","authors":"P. Bhattacharya, S. Mukherjee, Upasana Bhattacharya, R. Bhattacharya, Ritwick Bhattacharya, Rupsa Bhattacharya, Dalia Mukherjee, Ayishee Mukherjee, Debasis Mukherjee, H. Banerjee, S. Panda, A. Roy","doi":"10.15406/ICPJL.2018.06.00160","DOIUrl":"https://doi.org/10.15406/ICPJL.2018.06.00160","url":null,"abstract":"Idiopathic Pulmonary Fibrosis (IPF) is a chronic inflammatory lung disorder which gradually process to establish fibrosis. This condition is found more commonly in men, but is rarest in younger than age 50 years and median age of diagnosis is about 65 years.1 Although the disease course is variable, unpredictable (some patients progress rapidly, other quite slowly and others have sudden worsening after periods of stability with nintedancib). The median survival time is 2-4 years after diagnosis. Though the incidence of this disease is low in India (0.5), and in the Asian countries (4.2) per 1 lack population per year, the incidence is very high in European and in north American countries, Canada etc and its incidence there is between 2.8-18 per 1 lack population per year. Anti-Inflammatory therapies with prednisolone, or prednisolone with immunosuppressive agents like azathioprine for long years did not improve the outcome rather was found putative and subsequent meta analysis with prednisolone or prednisolone with azathioprine or acytyl cysteine or warfarin or everolemus was later proved to be potentially harmful therapies. Treatment by bosenten, imatinib, mactraintan or sidenafil was also attempted since 2010-2015 but were considered potentially ineffective therapies for IPF. That are now accepted worldwide A tyrosine kinase inhibitors (rho-rho kinase pathway inhibitors) nintedanib and anti fibrogenic agent Pirfenidone (TGFB2 inhibitors). IPF is now generally regarded as a consequence of multiple interacting genetic and environmental risk factors with repetitive local micro injuries to aging alveolar epithelium. These micro injuries stimulate fibroblasts proliferation, produces extra cellular matrix expansions and altered matrix composition and biomechanics, induces matrix produces myofibroblast and aberrant remodeling of lung interstitium.2","PeriodicalId":92215,"journal":{"name":"International clinical pathology journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41942532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0