Practical diabetes international : the journal for diabetes care teams worldwide最新文献_第5页

The enigma of diagnosing and managing diabetic peripheral neuropathic pain in everyday practice: time to QOF up? 日常实践中糖尿病周围神经性疼痛的诊断和治疗之谜:是时候QOF了?

Practical diabetes international : the journal for diabetes care teams worldwide Pub Date : 2011-05-01 DOI: 10.1002/PDI.1580

S. Davies, D. Coppini

引用次数: 0

Insulin therapy in patients with cystic fibrosis related diabetes mellitus: benefit, timing of initiation and hypoglycaemia 囊性纤维化相关性糖尿病患者的胰岛素治疗:获益、起始时间和低血糖

Practical diabetes international : the journal for diabetes care teams worldwide Pub Date : 2011-05-01 DOI: 10.1002/PDI.1588

Rs Drummond, E. Ross, S. Bicknell, M. Small, G. Jones

{"title":"Insulin therapy in patients with cystic fibrosis related diabetes mellitus: benefit, timing of initiation and hypoglycaemia","authors":"Rs Drummond, E. Ross, S. Bicknell, M. Small, G. Jones","doi":"10.1002/PDI.1588","DOIUrl":"https://doi.org/10.1002/PDI.1588","url":null,"abstract":"Pancreatic endocrine dysfunction in patients with cystic fibrosis heralds declining pulmonary function and a six-fold rise in mortality. Insulin therapy increases weight and reduces decline in lung function. Optimal timing of initiation remains contentious but early intervention may maximise benefit. We explored the optimal timing of initiation of therapy and characterised the frequency and usual symptoms of hypoglycaemia. \u0000 \u0000 \u0000 \u0000Fifty-four patients with cystic fibrosis treated with insulin were compared up to five years pre and post insulin initiation with respect to weight gain and lung function. Frequency and usual symptoms of hypoglycaemia were assessed using the Hypoglycemia Symptoms Awareness Questionnaire. \u0000 \u0000 \u0000 \u0000Mean age was 27.6(16–52) years. In the five years preceding insulin therapy, FEV1 declined from 2.6±0.14L to 1.78±0.12L (p<0.001). In the group as a whole, rate of decline was arrested with insulin initiation; the mean five-year post insulin FEV1 was 1.74±0.20L (p=0.15). When stratified according to oral glucose tolerance testing at initiation the rate of decline was significant in patients with impaired glucose tolerance (p=0.02) but not normal glucose tolerance nor overt cystic fibrosis diabetes mellitus. Insulin therapy increased weight from 53.08±1.53kg to 56.22±2.08kg (p=0.05). Hypoglycaemia was common and 75% of respondents scored results indicative of hypoglycaemia unawareness. \u0000 \u0000 \u0000 \u0000This study confirms that the favourable effect of insulin upon lung function in patients with cystic fibrosis correlates with the degree of glucose intolerance at baseline. Hypoglycaemia is an important clinical issue. Copyright © 2011 John Wiley & Sons.","PeriodicalId":92116,"journal":{"name":"Practical diabetes international : the journal for diabetes care teams worldwide","volume":"69 5","pages":"177-182"},"PeriodicalIF":0.0,"publicationDate":"2011-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/PDI.1588","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51025063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Assessing patients' knowledge about their diabetes 评估患者对糖尿病的认知

Practical diabetes international : the journal for diabetes care teams worldwide Pub Date : 2011-05-01 DOI: 10.1002/PDI.1582

A. Brooks

引用次数: 0

Diabetic retinal disease: anti‐VEGF agents are a promising line of therapy 糖尿病视网膜疾病:抗VEGF药物是一种很有前途的治疗方法

Practical diabetes international : the journal for diabetes care teams worldwide Pub Date : 2011-05-01 DOI: 10.1002/PDI.1581

K. Shotliff, N. Davies

引用次数: 0

Rapid weight loss and pain in the foot 体重迅速减轻，脚部疼痛

Practical diabetes international : the journal for diabetes care teams worldwide Pub Date : 2011-05-01 DOI: 10.1002/PDI.1585

M. Kong, K. Nisal, R. Gregory

引用次数: 0

Working with people who are difficult to help 与难以帮助的人一起工作

Practical diabetes international : the journal for diabetes care teams worldwide Pub Date : 2011-04-01 DOI: 10.1002/PDI.1576

M. Davies

引用次数: 0

‘Missed’ coeliac disease in type 1 diabetes mellitus with fatal consequences 1型糖尿病“漏诊”乳糜泻伴致命后果

Practical diabetes international : the journal for diabetes care teams worldwide Pub Date : 2011-04-01 DOI: 10.1002/PDI.1570

F. Talbot, S. Neupane, A. Gibbons, S. Krishnan, A. Mathews

{"title":"‘Missed’ coeliac disease in type 1 diabetes mellitus with fatal consequences","authors":"F. Talbot, S. Neupane, A. Gibbons, S. Krishnan, A. Mathews","doi":"10.1002/PDI.1570","DOIUrl":"https://doi.org/10.1002/PDI.1570","url":null,"abstract":"Our patient is a 40-year-old man with a 22-year history of type 1 diabetes. His control had been consistently poor but he had minimal end organ damage. There was no significant past medical history or family history. He was a C1 driving licence holder, and the DVLA was aware of his diagnosis of type 1 diabetes. \u0000 \u0000 \u0000 \u0000In January 2007 he unexpectedly lost 8kg in weight and found he required less insulin. He had frequent hypoglycaemic episodes, but did not seek medical attention. \u0000 \u0000 \u0000 \u0000Five months later he was involved in a road traffic accident that was fatal to the other driver. The paramedics found him to be hypoglycaemic. This resulted in a custodial sentence, and lifetime driving ban. \u0000 \u0000 \u0000 \u0000He was subsequently admitted to hospital to investigate his hypoglycaemia. Thyroid function and synacthen tests were normal. Coeliac serology was negative and he was mildly anaemic. His HbA1c was elevated at 10.4% (90mmol/mol). He was discharged without cause found. \u0000 \u0000 \u0000 \u0000A month later he was readmitted with breathlessness. He was severely anaemic with an Hb of 7.8g/dl, and was referred for gastroscopy. This demonstrated hyperplastic gastritis of the stomach, with altered blood present. Duodenal biopsies were taken and showed subtotal villous atrophy with a patchy increase in intraepithelial lymphocytes and crypt hyperplasia. The findings were consistent with coeliac disease. The patient was referred to a dietitian for advice on a gluten-free diet. His haemoglobin normalised and a DEXA scan excluded osteoporosis. Copyright © 2011 John Wiley & Sons.","PeriodicalId":92116,"journal":{"name":"Practical diabetes international : the journal for diabetes care teams worldwide","volume":"53 4","pages":"110-112"},"PeriodicalIF":0.0,"publicationDate":"2011-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/PDI.1570","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51025150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Technological advances in pregnancy complicated by type 1 diabetes 妊娠合并1型糖尿病的技术进步

Practical diabetes international : the journal for diabetes care teams worldwide Pub Date : 2011-04-01 DOI: 10.1002/PDI.1568

H. Murphy, D. Elleri, K. Kumareswaran, R. Hovorka

引用次数: 1

High prevalence of abnormal glucose regulation in patients presenting for routine coronary angiography 常规冠状动脉造影患者血糖调节异常的高发率

Practical diabetes international : the journal for diabetes care teams worldwide Pub Date : 2011-04-01 DOI: 10.1002/PDI.1572

C. English, J. Hastings, S. Hennessy, S. Dinneen, J. Crowley

{"title":"High prevalence of abnormal glucose regulation in patients presenting for routine coronary angiography","authors":"C. English, J. Hastings, S. Hennessy, S. Dinneen, J. Crowley","doi":"10.1002/PDI.1572","DOIUrl":"https://doi.org/10.1002/PDI.1572","url":null,"abstract":"glucose metabolism is a known risk factor for coronary artery disease (CAD) and is frequently unrecognised even in patients with acute coronary syndrome. Patients with stable coronary symptoms frequently have multiple risk factors and may have no assessment of glucose regulation. The purpose of this study was to assess the prevalence of impaired glucose tolerance (IGT) and diabetes mellitus (DM) in a group of patients with stable symptoms presenting for coronary angiography. A modified oral glucose tolerance test (OGTT) was performed on 182 unselected patients undergoing elective angiography. Patients with known DM were excluded. Demographic data including cardiovascular risk factors, body mass index (BMI), and history of CAD were recorded. In all, 182 patients with a mean age of 62.1 years (±10.7 years) were studied. Indications for angiography were suspected angina. By WHO criteria an abnormal two-hour glucose was present in 49% of individuals, with 10.4% of these patients having overt DM. An abnormal two-hour glucose was seen in 63.2% of patients with significant CAD compared with 40.3% with normal or insignificant disease (p=0.004); 48.9% of patients with IGT or DM had normal fasting plasma glucose (FPG). In 78% of patients, BMI was over 25kg/m2. In this high risk population with multiple risk factors for CAD, previously undetected IGT and overt DM are very common. Almost two-thirds of patients with significant CAD had abnormal glucose regulation. The use of an FPG test alone may miss a significant number of patients with unrecognised glucose intolerance. Copyright © 2011 John Wiley & Sons. Practical Diabetes Int 2011; 28(3): 115-118","PeriodicalId":92116,"journal":{"name":"Practical diabetes international : the journal for diabetes care teams worldwide","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2011-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/PDI.1572","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51025210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Lipoatrophy associated with insulin aspart in continuous subcutaneous insulin infusion 持续皮下胰岛素输注与胰岛素分离相关的脂肪萎缩

Practical diabetes international : the journal for diabetes care teams worldwide Pub Date : 2011-04-01 DOI: 10.1002/PDI.1569

P. George, M. Robertson, L. Grant, A. Mackie

引用次数: 1