Journal of comorbidity最新文献

{"title":"Multimorbidity of four cardiometabolic and chronic pulmonary disease groups: prevalence and attributable fraction in US adults, 2007-2012.","authors":"Lisa R Staimez, Melissa Y Wei, Min Kim, K M Venkat Narayan, Sharon H Saydah","doi":"10.15256/joc.2017.7.89","DOIUrl":"10.15256/joc.2017.7.89","url":null,"abstract":"<p><strong>Background: </strong>Cardiometabolic and chronic pulmonary diseases may be associated with modifiable risk factors that can be targeted to prevent multimorbidity.</p><p><strong>Objectives: </strong>(i) Estimate the prevalence of multimorbidity across four cardiometabolic and chronic pulmonary disease groups; (ii) compare the prevalence of multimorbidity to that of one disease and no disease; and (iii) quantify population attributable fractions (PAFs) for modifiable risk factors of multimorbidity.</p><p><strong>Design: </strong>Data from adults aged 18-79 years who participated in the US National Health and Nutrition Examination Survey 2007-2012 were examined. Multimorbidity was defined as ≥2 co-occurring diseases across four common cardiometabolic and chronic pulmonary disease groups. Multivariate-adjusted PAFs for poverty, obesity, smoking, hypertension, and low high-density lipoprotein (HDL) cholesterol were estimated.</p><p><strong>Results: </strong>Among 16,676 adults, the age-standardized prevalence of multimorbidity was 9.3%. The occurrence of multimorbidity was greater with age, from 1.5% to 5.9%, 15.0% and 34.8% for adults aged 18-39, 40-54, 55-64 and 65-79 years, respectively. Multimorbidity was greatest among the poorest versus non-poorest adults and among blacks versus other races/ethnicities. Multimorbidity was also greater in adults with obesity, hypertension, and low HDL cholesterol. Risk factors with greatest PAFs were hypertension (38.8%; 95% confidence interval [CI] 29.4-47.4) and obesity (19.3%; 95% CI 10.2-28.2).</p><p><strong>Conclusions: </strong>In the USA, 9.3% of adults have multimorbidity across four chronic disease groups, with a disproportionate burden among older, black, and poor adults. Our results suggest that targeting two <i>intermediate</i> modifiable risk factors, hypertension and obesity, might help to reduce the prevalence of multimorbidity in US adults.</p>","PeriodicalId":92071,"journal":{"name":"Journal of comorbidity","volume":"7 1","pages":"22-32"},"PeriodicalIF":0.0,"publicationDate":"2017-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556435/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35211595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patients with multimorbidity and their experiences with the healthcare process: a scoping review.","authors":"Maartje J van der Aa, Jennifer R van den Broeke, Karien Stronks, Thomas Plochg","doi":"10.15256/joc.2017.7.97","DOIUrl":"10.15256/joc.2017.7.97","url":null,"abstract":"<p><strong>Background: </strong>The number of patients with multimorbidity (two or more conditions) is increasing. Observational research has shown that having multiple health problems is associated with poorer outcomes in terms of health, quality of care, and costs. Thus, it is imperative to understand how patients with multimorbidity experience their healthcare process. Insight into patient experiences can be used to tailor healthcare provision specifically to the needs of patients with multimorbidity.</p><p><strong>Objective: </strong>To synthesize self-reported experiences with the healthcare process of patients with multimorbidity, and identify overarching themes.</p><p><strong>Design: </strong>A scoping literature review that evaluates both qualitative and quantitative studies published in PubMed, Embase, MEDLINE, and PsycINFO. No restrictions were applied to healthcare setting or year of publication. Studies were included if they reported experiences with the healthcare process of patients with multimorbidity. Patient experiences were extracted and subjected to thematic analysis (interpretative), which revealed overarching themes by mapping their interrelatedness.</p><p><strong>Results: </strong>Overall, 22 empirical studies reported experiences of patients with multimorbidity. Thematic analysis identified 12 themes within these studies. The key overarching theme was the experience of a lack of holistic care. Patients also experienced insufficient guidance from healthcare providers. Patients also perceived system-related issues such as problems stemming from poor professional-to-professional communication.</p><p><strong>Conclusions: </strong>Patients with multimorbidity experience a range of system- and professional-related issues with healthcare delivery. This overview illustrates the diversity of aspects that should be considered in designing healthcare services for patients with multimorbidity.</p>","PeriodicalId":92071,"journal":{"name":"Journal of comorbidity","volume":"7 1","pages":"11-21"},"PeriodicalIF":0.0,"publicationDate":"2017-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35211594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Glasgow 'Deep End' Links Worker Study Protocol: a quasi-experimental evaluation of a social prescribing intervention for patients with complex needs in areas of high socioeconomic deprivation.","authors":"Stewart W Mercer,&nbsp;Bridie Fitzpatrick,&nbsp;Lesley Grant,&nbsp;Nai Rui Chng,&nbsp;Catherine A O'Donnell,&nbsp;Mhairi Mackenzie,&nbsp;Alex McConnachie,&nbsp;Andisheh Bakhshi,&nbsp;Sally Wyke","doi":"10.15256/joc.2017.7.102","DOIUrl":"https://doi.org/10.15256/joc.2017.7.102","url":null,"abstract":"<p><strong>Background: </strong>'Social prescribing' can be used to link patients with complex needs to local (non-medical) community resources. The 'Deep End' Links Worker Programme is being tested in general practices serving deprived populations in Glasgow, Scotland.</p><p><strong>Objectives: </strong>To assess the implementation and impact of the intervention at patient and practice levels.</p><p><strong>Methods: </strong><i>Study design</i>: Quasi-experimental outcome evaluation with embedded theory-driven process evaluation in 15 practices randomized to receive the intervention or not. <i>Complex intervention</i>: Comprising a practice development fund, a practice-based community links practitioner (CLP), and management support. It aims to link patients to local community organizations and enhance practices' social prescribing capacity. <i>Study population</i>: For intervention practices, staff and adult patients involved in referral to a CLP, and a sample of community organization staff. For comparison practices, all staff and a random sample of adult patients. <i>Sample size</i>: 286 intervention and 484 comparator patients. <i>Outcomes</i>: Primary patient outcome is health-related quality of life (EQ-5D-5L). Secondary patient outcomes include capacity, depression/anxiety, self-esteem, and healthcare utilization. Practice outcome measures include team climate, job satisfaction, morale, and burnout. Outcomes measured at baseline and 9 months. <i>Processes</i>: Barriers and facilitators to implementation of the programme and possible mechanisms through which outcomes are achieved. <i>Analysis plan</i>: For outcome, intention-to-treat analysis with differences between groups tested using mixed-effects regression models. For process, case-study approach with thematic analysis.</p><p><strong>Discussion: </strong>This evaluation will provide new evidence about the implementation and impact of social prescribing by general practices serving patients with complex needs living in areas of high deprivation.</p>","PeriodicalId":92071,"journal":{"name":"Journal of comorbidity","volume":"7 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2017-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.15256/joc.2017.7.102","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35211593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A qualitative interpretation of challenges associated with helping patients with multiple chronic diseases identify their goals.","authors":"Pauline Boeckxstaens,&nbsp;Sara Willems,&nbsp;Mieke Lanssens,&nbsp;Charlotte Decuypere,&nbsp;Guy Brusselle,&nbsp;Thomas Kühlein,&nbsp;Jan De Maeseneer,&nbsp;An De Sutter","doi":"10.15256/joc.2016.6.64","DOIUrl":"https://doi.org/10.15256/joc.2016.6.64","url":null,"abstract":"<p><strong>Background: </strong>Patients with multiple chronic diseases are usually treated according to disease-specific guidelines, with outcome measurements focusing mostly on biomedical indicators (e.g. blood sugar levels or lung function). However, for multimorbidity, a goal-oriented approach focusing on the goals defined by the individual patient, may be more suitable. Despite the clear theoretical and conceptual advantages of including patient-defined goals in clinical decision-making for multimorbidity, it is not clear how patients define their goals and which aspects play a role in the process of defining them.</p><p><strong>Objective: </strong>To explore goal-setting in patients with multimorbidity.</p><p><strong>Design: </strong>Qualitative analysis of interviews with 19 patients diagnosed with chronic obstructive pulmonary disease and comorbidities.</p><p><strong>Results: </strong>Patients do not naturally present their goals. Their goals are difficult to elicit, even when different interviewing techniques are used. Four underlying hypotheses which may explain this finding were identified from the interviews: (1) patients cannot identify with the concept of goal-setting; (2) goal-setting is reduced due to acceptation; (3) actual stressors predominate over personal goal-setting; and (4) patients may consider personal goals as selfish.</p><p><strong>Conclusions: </strong>Our findings advocate for specific attention to provider skills and strategies that help patients identify their personal goals. The hypotheses on why patients may struggle with defining goals may be useful to prompt patients in this process and support the development of a clinical method for goal-oriented care.</p>","PeriodicalId":92071,"journal":{"name":"Journal of comorbidity","volume":"6 2","pages":"120-126"},"PeriodicalIF":0.0,"publicationDate":"2016-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.15256/joc.2016.6.64","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35510755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrated multimorbidity management in primary care: why, what, how, and how to?","authors":"Joachim P Sturmberg, Richard J Botelho, Bruno Kissling","doi":"10.15256/joc.2016.6.95","DOIUrl":"10.15256/joc.2016.6.95","url":null,"abstract":"The epidemic of multimorbidity Policymakers regard “the epidemic of multimorbidity” as the greatest threat to the sustainability of healthcare systems. They believe the solution is “integrated care”, “ The search to connect the healthcare system (acute, primary medical and skilled) with other human service systems (e.g. long-term care, education and vocational and housing services) in order to improve outcomes (clinical, satisfaction, and efficiency)” [1]. This definition includes key characteristics of complex adaptive systems. People act as agents who evolve in their characteristics and behaviours over time. These agents constantly learn and adapt in real time to changing contexts. These systems display emergent dynamic non-linear behaviours resulting from ongoing iterative feedback amongst their agents. Emergent outcomes do not have linear “cause and effect” relationships and can best be understood in hindsight. Emergent behaviours are highly sensitive to context; consequently, the “same” approach used by different agents in different contexts will not produce the same outcomes. Agents navigate toward mutually agreed outcomes by constantly adapting to evolving changes within the context of local constraints [2]. A complex adaptive system approach overcomes many of the dysfunctions in the current health systems, in particular the fragmentation of patient care [3]. Overcoming fragmentation requires continuous adaptation to changing circumstances – a constant challenge for patients, health professionals, community service providers, and policymakers. How can the already overburdened primary healthcare services achieve these goals? To address the complex challenge, we first must reflect on three key questions: What is health? What is disease? What is multimorbidity? Journal of Comorbidity 2016;6(2):114–119","PeriodicalId":92071,"journal":{"name":"Journal of comorbidity","volume":"6 2","pages":"114-119"},"PeriodicalIF":0.0,"publicationDate":"2016-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.15256/joc.2016.6.95","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35510309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are care plans suitable for the management of multiple conditions?","authors":"Charlotte E Young,&nbsp;Frances M Boyle,&nbsp;Allyson J Mutch","doi":"10.15256/joc.2016.6.79","DOIUrl":"https://doi.org/10.15256/joc.2016.6.79","url":null,"abstract":"<p><strong>Background: </strong>Care plans have been part of the primary care landscape in Australia for almost two decades. With an increasing number of patients presenting with multiple chronic conditions, it is timely to consider whether care plans meet the needs of patients and clinicians.</p><p><strong>Objectives: </strong>To review and benchmark existing care plan templates that include recommendations for comorbid conditions, against four key criteria: (i) patient preferences, (ii) setting priorities, (iii) identifying conflicts and synergies between conditions, and (iv) setting dates for reviewing the care plan.</p><p><strong>Design: </strong>Document analysis of Australian care plan templates published from 2006 to 2014 that incorporated recommendations for managing comorbid conditions in primary care.</p><p><strong>Results: </strong>Sixteen templates were reviewed. All of the care plan templates addressed patient preference, but this was not done comprehensively. Only three templates included setting priorities. None assisted in identifying conflicts and synergies between conditions. Fifteen templates included setting a date for reviewing the care plan.</p><p><strong>Conclusions: </strong>Care plans are a well-used tool in primary care practice, but their current format perpetuates a single-disease approach to care, which works contrary to their intended purpose. Restructuring care plans to incorporate shared decision-making and attention to patient preferences may assist in shifting the focus back to the patient and their care needs.</p>","PeriodicalId":92071,"journal":{"name":"Journal of comorbidity","volume":"6 2","pages":"103-113"},"PeriodicalIF":0.0,"publicationDate":"2016-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.15256/joc.2016.6.79","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35510308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Involving patients with multimorbidity in service planning: perspectives on continuity and care coordination.","authors":"Michaela L Schiøtz,&nbsp;Dorte Høst,&nbsp;Anne Frølich","doi":"10.15256/joc.2016.6.81","DOIUrl":"https://doi.org/10.15256/joc.2016.6.81","url":null,"abstract":"<p><strong>Background: </strong>The prevalence of multiple comorbid chronic conditions, or multimorbidity, is increasing. Care provided to people with multimorbidity is often fragmented, incomplete, inefficient, and ineffective. As part of a research and development project focusing on improving care, we sought to involve patients with multimorbidity in the planning process.</p><p><strong>Objective: </strong>To identify opportunities for improving care by understanding how patients from a Danish University Hospital experience care coordination.</p><p><strong>Design: </strong>Qualitative semi-structured interviews with 14 patients with multimorbidity.</p><p><strong>Results: </strong>Patients with multimorbidity described important concerns about care that included: (1) disease-centered, rather than patient-centered, care; (2) lack of attention to comorbidities and patient preferences and needs; and (3) involvement of numerous healthcare providers with limited care coordination. Poor continuity of care resulted in lack of treatment for complex problems, such as pain and mental health issues, medication errors, adverse events, and a feeling of being lost in the system. Receiving care from generalists (e.g. general practitioners and healthcare professionals at prevention centers) and having a care coordinator seemed to improve patients' experience of continuity and coordination of care. Suggestions for service improvements when providing care for people with multimorbidity included using care coordinators, longer consultation times, consultations specifically addressing follow-up on prescribed medications, and shifting the focus of care from disease states to patients' overall health status.</p><p><strong>Conclusions: </strong>A need exists for a reorganization of care delivery for people with multimorbidity that focuses on improved care coordination and puts patient preferences at the center of care.</p>","PeriodicalId":92071,"journal":{"name":"Journal of comorbidity","volume":"6 2","pages":"95-102"},"PeriodicalIF":0.0,"publicationDate":"2016-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.15256/joc.2016.6.81","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35510307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Training doctors to manage patients with multimorbidity: a systematic review.","authors":"Cliona Lewis, Emma Wallace, Lorraine Kyne, Walter Cullen, Susan M Smith","doi":"10.15256/joc.2016.6.87","DOIUrl":"10.15256/joc.2016.6.87","url":null,"abstract":"<p><strong>Background: </strong>Patients with multimorbidity (two or more chronic conditions) are now the norm in clinical practice, and place an increasing burden on the healthcare system. Management of these patients is challenging, and requires doctors who are skilled in the complexity of multiple chronic diseases.</p><p><strong>Objective: </strong>To perform a systematic review of the literature to ascertain whether there are education and training formats which have been used to train postgraduate medical doctors in the management of patients with multimorbidity in primary and/or secondary care, and which have been shown to improve knowledge, skills, attitudes, and/or patient outcomes.</p><p><strong>Methods: </strong>Overall, 75,110 citations were screened, of which 65 full-text articles were then independently assessed for eligibility by two reviewers, and two studies met the inclusion criteria for the review.</p><p><strong>Results: </strong>The two included studies implemented and evaluated multimorbidity workshops, and highlight the need for further research addressing the learning needs of doctors tasked with managing patients with multimorbidity in their daily practice.</p><p><strong>Conclusion: </strong>While much has been published about the challenges presented to medical staff by patients with multimorbidity, published research regarding education of doctors to manage these problems is lacking. Further research is required to determine whether there is a need for, or benefit from, specific training for doctors to manage patients with multimorbidity. PROSPERO registration number: CRD42013004010.</p>","PeriodicalId":92071,"journal":{"name":"Journal of comorbidity","volume":"6 2","pages":"85-94"},"PeriodicalIF":0.0,"publicationDate":"2016-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556450/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35510306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meeting the needs of a complex population: a functional health- and patient-centered approach to managing multimorbidity.","authors":"Tara Sampalli,&nbsp;Robert Dickson,&nbsp;Jill Hayden,&nbsp;Lynn Edwards,&nbsp;Arun Salunkhe","doi":"10.15256/joc.2016.6.83","DOIUrl":"https://doi.org/10.15256/joc.2016.6.83","url":null,"abstract":"<p><p>Individuals with multimorbidity have complex care needs along with significant impacts to their functional health and quality of life. Recent evidence-based and experience-based explorations have revealed the importance of patient perspectives and functional health management in improving care delivery and health outcomes for individuals with multimorbidity. The impact of managing multimorbidity is evident at multiple levels of healthcare - the individual, the provider, and the system. Our local experience dealing with these challenges has led to the development of a functional health model that includes patient perspectives in care delivery within the Integrated Chronic Care Service (ICCS) of the health authority in Nova Scotia. In this paper, we present a discussion of the challenges, guiding models, and service-level transformations that have been integrated into care delivery at the ICCS to meet the healthcare needs of people with multiple health conditions. We describe our redesign strategies for care team planning, treatment approach, and patient inclusion.</p>","PeriodicalId":92071,"journal":{"name":"Journal of comorbidity","volume":"6 2","pages":"76-84"},"PeriodicalIF":0.0,"publicationDate":"2016-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.15256/joc.2016.6.83","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35510305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The <i>Journal of Comorbidity</i> affiliates with the Society for Academic Primary Care.","authors":"Susan M Smith,&nbsp;Joanne Reeve,&nbsp;Jane Gunn,&nbsp;Nathan R Hill,&nbsp;Martin Fortin,&nbsp;Catherine A O'Donnell,&nbsp;Marjan van den Akker,&nbsp;Joanne Protheroe,&nbsp;Stewart W Mercer","doi":"10.15256/joc.2016.6.88","DOIUrl":"https://doi.org/10.15256/joc.2016.6.88","url":null,"abstract":"The Journal of Comorbidity and the Society for Academic Primary Care (SAPC) are pleased to announce an exciting new partnership aimed at strengthening collaborations and enhancing opportunities among primary care professionals with an interest in comorbidity and multimorbidity. The Journal of Comorbidity and SAPC share a mutual goal to improve the management and care of patients by making clinical and research information and perspectives available to a global network of healthcare professionals. This new partnership will be an invaluable contribution to expanding the research platform for discussions and the scholarly exchange of knowledge, ideas, and research on comorbidity and multimorbidity. Journal of Comorbidity 2016;6(2):73–75","PeriodicalId":92071,"journal":{"name":"Journal of comorbidity","volume":"6 2","pages":"73-75"},"PeriodicalIF":0.0,"publicationDate":"2016-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.15256/joc.2016.6.88","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35510304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}