Procedia manufacturing最新文献

Reconfigurable Antenna for Wi-Fi and 5G Applications 适用于Wi-Fi和5G应用的可重构天线

Procedia manufacturing Pub Date : 2023-05-15 DOI: 10.1016/j.promfg.2020.04.007

Doae El Hadri, A. Zakriti, A. Zugari

引用次数: 7

Identification and structural basis of an enzyme that degrades oligosaccharides in caramel. 鉴定一种降解焦糖中低聚糖的酶及其结构基础。

Procedia manufacturing Pub Date : 2023-03-29 eCollection Date: 2023-01-01 DOI: 10.2142/biophysico.bppb-v20.0017

Toma Kashima, Akihiro Ishiwata, Kiyotaka Fujita, Shinya Fushinobu

{"title":"Identification and structural basis of an enzyme that degrades oligosaccharides in caramel.","authors":"Toma Kashima, Akihiro Ishiwata, Kiyotaka Fujita, Shinya Fushinobu","doi":"10.2142/biophysico.bppb-v20.0017","DOIUrl":"10.2142/biophysico.bppb-v20.0017","url":null,"abstract":"<p><p>Cooking with fire produces foods containing carbohydrates that are not naturally occurring, such as α-d-fructofuranoside found in caramel. Each of the hundreds of compounds produced by caramelization reactions is considered to possess its own characteristics. Various studies from the viewpoints of biology and biochemistry have been conducted to elucidate some of the scientific characteristics. Here, we review the composition of caramelized sugars and then describe the enzymatic studies that have been conducted and the physiological functions of the caramelized sugar components that have been elucidated. In particular, we recently identified a glycoside hydrolase (GH), GH172 difructose dianhydride I synthase/hydrolase (αFFase1), from oral and intestinal bacteria, which is implicated in the degradation of oligosaccharides in caramel. The structural basis of αFFase1 and its ligands provided many insights. This discovery opened the door to several research fields, including the structural and phylogenetic relationship between the GH172 family enzymes and viral capsid proteins and the degradation of cell membrane glycans of acid-fast bacteria by some αFFase1 homologs. This review article is an extended version of the Japanese article, Identification and Structural Basis of an Enzyme Degrading Oligosaccharides in Caramel, published in SEIBUTSU BUTSURI Vol. 62, p. 184-186 (2022).</p>","PeriodicalId":91947,"journal":{"name":"Procedia manufacturing","volume":"8 1","pages":"e200017"},"PeriodicalIF":0.0,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10941961/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76796845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combined proteomic and biochemical analyses redefine the consensus sequence requirement for epidermal growth factor-like domain hydroxylation. 蛋白质组学和生化分析重新定义了表皮生长因子样结构域羟基化的共识序列要求。

Procedia manufacturing Pub Date : 2022-08-01 Epub Date: 2022-06-11 DOI: 10.1016/j.jbc.2022.102129

Lennart Brewitz, Bruce C Onisko, Christopher J Schofield

{"title":"Combined proteomic and biochemical analyses redefine the consensus sequence requirement for epidermal growth factor-like domain hydroxylation.","authors":"Lennart Brewitz, Bruce C Onisko, Christopher J Schofield","doi":"10.1016/j.jbc.2022.102129","DOIUrl":"10.1016/j.jbc.2022.102129","url":null,"abstract":"<p><p>Epidermal growth factor-like domains (EGFDs) have important functions in cell-cell signaling. Both secreted and cell surface human EGFDs are subject to extensive modifications, including aspartate and asparagine residue C3-hydroxylations catalyzed by the 2-oxoglutarate oxygenase aspartate/asparagine-β-hydroxylase (AspH). Although genetic studies show AspH is important in human biology, studies on its physiological roles have been limited by incomplete knowledge of its substrates. Here, we redefine the consensus sequence requirements for AspH-catalyzed EGFD hydroxylation based on combined analysis of proteomic mass spectrometric data and mass spectrometry-based assays with isolated AspH and peptide substrates. We provide cellular and biochemical evidence that the preferred site of EGFD hydroxylation is embedded within a disulfide-bridged macrocycle formed of 10 amino acid residues. This definition enabled the identification of previously unassigned hydroxylation sites in three EGFDs of human fibulins as AspH substrates. A non-EGFD containing protein, lymphocyte antigen-6/plasminogen activator urokinase receptor domain containing protein 6B (LYPD6B) was shown to be a substrate for isolated AspH, but we did not observe evidence for LYPD6B hydroxylation in cells. AspH-catalyzed hydroxylation of fibulins is of particular interest given their important roles in extracellular matrix dynamics. In conclusion, these results lead to a revision of the consensus substrate requirements for AspH and expand the range of observed and potential AspH-catalyzed hydroxylation in cells, which will enable future study of the biological roles of AspH.</p>","PeriodicalId":91947,"journal":{"name":"Procedia manufacturing","volume":"3 1","pages":"102129"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293771/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82162115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of COVID-19 Cases in Kosova. 科索沃COVID-19病例的管理

Procedia manufacturing Pub Date : 2022-06-13 eCollection Date: 2022-06-01 DOI: 10.36519/idcm.2022.125

Salih Ahmeti, Şiran Keske, Sadije Namani-Avdiu, Lindita Ajazaj-Berisha, Arben Vishaj, Izet Sadik, Mentor Alimusaj, Faik Hoti, Hysen Ahmeti, Bilgin Sait, Nahit Çakar, Önder Ergönül

引用次数: 0

NAMRC 49 Fast-Tracked Research Papers to Journal of Manufacturing Systems and Journal of Manufacturing Processes 《制造系统学报》和《制造过程学报》49篇快速跟踪研究论文

Procedia manufacturing Pub Date : 2021-01-01 Epub Date: 2021-07-08 DOI: 10.1016/j.promfg.2021.06.003

Ihab Ragai, Robert X. Gao, Livan Fratini

引用次数: 0

Geometric Reasoning enabled One Shot Learning for Robotic Tasks 几何推理使机器人任务的一次性学习成为可能

Procedia manufacturing Pub Date : 2021-01-01 Epub Date: 2021-11-03 DOI: 10.1016/j.promfg.2021.10.006

Markus Ikeda , Markus Ganglbauer , Naresh Chitturi , Andreas Pichler

{"title":"Geometric Reasoning enabled One Shot Learning for Robotic Tasks","authors":"Markus Ikeda , Markus Ganglbauer , Naresh Chitturi , Andreas Pichler","doi":"10.1016/j.promfg.2021.10.006","DOIUrl":"10.1016/j.promfg.2021.10.006","url":null,"abstract":"<div><p>Flexible robotics will be a major enabling technology for the application of robot-based automation in other than traditionally suitable automotive or electronics production with high volumes. Increased demand for flexibility due to individualized production typical for most SMEs require an increased level of flexibility – also for robots that should be able to learn as well as provide an increased level of autonomy due to improved skills and extended reasoning capabilities. This publication tries to find out if novel ANN methodology that is able to process 3D surface data is applicable to generalize process knowledge in a one shot learning by demonstration situation in order to be able to execute tasks on similar but geometrically unequal objects in future settings. The methodology generalizes not on symbolic or trajectory level but on surface geometry level and was applied to a simple geometric object on lab scale. The algorithms introduced are applicable to more complex objects with practical relevance.</p></div>","PeriodicalId":91947,"journal":{"name":"Procedia manufacturing","volume":"55 ","pages":"Pages 32-39"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2351978921002031/pdf?md5=6000695b38374e28e63e08d2f1204fa3&pid=1-s2.0-S2351978921002031-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54985396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Enabling cross-sectorial, circular economy transition in SME via digital platform integrated operational services 通过数字平台综合运营服务，实现中小企业跨行业循环经济转型

Procedia manufacturing Pub Date : 2021-01-01 Epub Date: 2021-07-30 DOI: 10.1016/j.promfg.2021.07.048

Gianfranco Pedone , Richárd Beregi , Krisztián Balázs Kis , Marcello Colledani

{"title":"Enabling cross-sectorial, circular economy transition in SME via digital platform integrated operational services","authors":"Gianfranco Pedone , Richárd Beregi , Krisztián Balázs Kis , Marcello Colledani","doi":"10.1016/j.promfg.2021.07.048","DOIUrl":"10.1016/j.promfg.2021.07.048","url":null,"abstract":"<div><p>Circular Economy (CE) is an emerging paradigm aiming at establishing a new sustainable development path by decoupling economic growth and resource consumption. The main limitation in current production models is that manufacturing and de-and remanufacturing operations are carried out independently and without sharing information and economic benefits. This can be overcome by rethinking the current European industrial system into new collaborative and sustainable value networks. New business cases can be generated also for individual Small and Medium Enterprises (SME) by taking advantage of the connection with the Industry 4.0 opportunities and by building on cross-sectorial markets and the potential of digital solutions. The operational services (DOS) presented in this paper are the key part of a novel digital platform called DigiPrime, whose aim is to provide SME with a federated service infrastructure that help overcome the current information asymmetry and explore the possibility to access and transit towards a CE cross-sectorial value-chain. The manuscript presents a selection of DOS considered fundamental for an SME in such a process, through a relevant exploitation use-case scenario. The combination of such DOS has been validated within the project for the case of an electric car repair-shop network and the preliminary outcome of their integration process is also outlined.</p></div>","PeriodicalId":91947,"journal":{"name":"Procedia manufacturing","volume":"54 ","pages":"Pages 70-75"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.promfg.2021.07.048","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54985283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A simulation driven development framework for parallel kinematics 一个仿真驱动的并行运动学开发框架

Procedia manufacturing Pub Date : 2021-01-01 Epub Date: 2021-11-03 DOI: 10.1016/j.promfg.2021.10.010

Lukas Bath , Thorsten Schüppstuhl

引用次数: 1

Hybrid Environment Reconstruction Improving User Experience and Workload in Augmented Virtuality Teleoperation 混合环境重构改善增强虚拟远程操作的用户体验和工作量

Procedia manufacturing Pub Date : 2021-01-01 Epub Date: 2021-11-03 DOI: 10.1016/j.promfg.2021.10.007

Andreas Blank , Emir Kosar , Engin Karlidag , Qiang Guo , Sebastian Kohn , Oliver Sommer , Jonas Walter , Meike Herbert , Julian Sessner , Frank Querfurth , Maximilian Metzner , Jörg Franke

{"title":"Hybrid Environment Reconstruction Improving User Experience and Workload in Augmented Virtuality Teleoperation","authors":"Andreas Blank , Emir Kosar , Engin Karlidag , Qiang Guo , Sebastian Kohn , Oliver Sommer , Jonas Walter , Meike Herbert , Julian Sessner , Frank Querfurth , Maximilian Metzner , Jörg Franke","doi":"10.1016/j.promfg.2021.10.007","DOIUrl":"10.1016/j.promfg.2021.10.007","url":null,"abstract":"<div><p>Concurrent with autonomous robots, teleoperation gains importance in industrial applications. This includes remote intervention scenarios and human-robot-cooperation during complex or harmful tasks operated from a distance. For an efficient teleoperation, an interface achieving a good user experience and relieving workload of the operators is decisive. Whereas virtual reality allows a spatial integration, environment reconstruction is often based on point clouds in combination with pre-known object models. Challenges exist in spatial representation, through bandwidth limitations and sensor interferences. Furthermore, the potential of knowledge augmentation for workload improvement is often not fully utilized. To overcome these challenges, we present a hybrid environment reconstruction method, which is adaptive regarding the integration of different data sources as well as their derived semantic information levels. For evaluation, a user study is performed. Thereby known procedures to measure usability, immersion, user experience and operator workload serve for evaluation and comparison.</p></div>","PeriodicalId":91947,"journal":{"name":"Procedia manufacturing","volume":"55 ","pages":"Pages 40-47"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2351978921002043/pdf?md5=1f19e0e51661fb8684b885ceaa817740&pid=1-s2.0-S2351978921002043-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54985410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assembly of film coverlays: development of a configurable gripper for process automation 薄膜覆盖层的装配:用于过程自动化的可配置夹具的开发

Procedia manufacturing Pub Date : 2021-01-01 Epub Date: 2021-11-03 DOI: 10.1016/j.promfg.2021.10.012

Marcello Valori , Vito Basile , Serena Ruggeri , Gianmauro Fontana , Simone Pio Negri , Jose A. Mulet Alberola , Irene Fassi

{"title":"Assembly of film coverlays: development of a configurable gripper for process automation","authors":"Marcello Valori , Vito Basile , Serena Ruggeri , Gianmauro Fontana , Simone Pio Negri , Jose A. Mulet Alberola , Irene Fassi","doi":"10.1016/j.promfg.2021.10.012","DOIUrl":"10.1016/j.promfg.2021.10.012","url":null,"abstract":"<div><p>Despite the widespread use of electronic devices and consumer products integrating flexible electronics, in industrial practice, the assembly process of film-based coverlays is still performed manually, and this, in turn, affects process accuracy in first place. Additionally, the related manual tasks can be troublesome for workers, causing stress and fatigue. As a result, such a process can represent a bottleneck in the fabrication of Flexible Printed Circuit Boards (FPCBs).</p><p>In the present paper, the architecture of a gripper is proposed as the core device of a completely automated film-coverlay assembly process. The architecture of the gripper is vacuum-based and exploits the action of several independent valves, enabling the grip configuration according to the geometry of the component. The gripper operation is shown by implementing specific solutions related to the removal of the coverlay protective film and partial coverlay thermal bonding, thus providing also a detailed description of the phases concerning a feasible automated assembly process. The results of the tests concerning the evaluation of both solutions are reported and discussed in the paper. Finally, a simplified gripper version is prototyped to perform some of the tests, and it is also used to preliminarily assess the performance of the gripping strategy, with good results.</p></div>","PeriodicalId":91947,"journal":{"name":"Procedia manufacturing","volume":"55 ","pages":"Pages 80-87"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2351978921002092/pdf?md5=40494aaa3523aad54dbf32e877b853dd&pid=1-s2.0-S2351978921002092-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54985483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3