{"title":"Reconfigurable Antenna for Wi-Fi and 5G Applications","authors":"Doae El Hadri, A. Zakriti, A. Zugari","doi":"10.1016/j.promfg.2020.04.007","DOIUrl":"https://doi.org/10.1016/j.promfg.2020.04.007","url":null,"abstract":"","PeriodicalId":91947,"journal":{"name":"Procedia manufacturing","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.promfg.2020.04.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44505166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Identification and structural basis of an enzyme that degrades oligosaccharides in caramel.","authors":"Toma Kashima, Akihiro Ishiwata, Kiyotaka Fujita, Shinya Fushinobu","doi":"10.2142/biophysico.bppb-v20.0017","DOIUrl":"10.2142/biophysico.bppb-v20.0017","url":null,"abstract":"<p><p>Cooking with fire produces foods containing carbohydrates that are not naturally occurring, such as α-d-fructofuranoside found in caramel. Each of the hundreds of compounds produced by caramelization reactions is considered to possess its own characteristics. Various studies from the viewpoints of biology and biochemistry have been conducted to elucidate some of the scientific characteristics. Here, we review the composition of caramelized sugars and then describe the enzymatic studies that have been conducted and the physiological functions of the caramelized sugar components that have been elucidated. In particular, we recently identified a glycoside hydrolase (GH), GH172 difructose dianhydride I synthase/hydrolase (αFFase1), from oral and intestinal bacteria, which is implicated in the degradation of oligosaccharides in caramel. The structural basis of αFFase1 and its ligands provided many insights. This discovery opened the door to several research fields, including the structural and phylogenetic relationship between the GH172 family enzymes and viral capsid proteins and the degradation of cell membrane glycans of acid-fast bacteria by some αFFase1 homologs. This review article is an extended version of the Japanese article, Identification and Structural Basis of an Enzyme Degrading Oligosaccharides in Caramel, published in SEIBUTSU BUTSURI Vol. 62, p. 184-186 (2022).</p>","PeriodicalId":91947,"journal":{"name":"Procedia manufacturing","volume":"8 1","pages":"e200017"},"PeriodicalIF":0.0,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10941961/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76796845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Procedia manufacturingPub Date : 2022-08-01Epub Date: 2022-06-11DOI: 10.1016/j.jbc.2022.102129
Lennart Brewitz, Bruce C Onisko, Christopher J Schofield
{"title":"Combined proteomic and biochemical analyses redefine the consensus sequence requirement for epidermal growth factor-like domain hydroxylation.","authors":"Lennart Brewitz, Bruce C Onisko, Christopher J Schofield","doi":"10.1016/j.jbc.2022.102129","DOIUrl":"10.1016/j.jbc.2022.102129","url":null,"abstract":"<p><p>Epidermal growth factor-like domains (EGFDs) have important functions in cell-cell signaling. Both secreted and cell surface human EGFDs are subject to extensive modifications, including aspartate and asparagine residue C3-hydroxylations catalyzed by the 2-oxoglutarate oxygenase aspartate/asparagine-β-hydroxylase (AspH). Although genetic studies show AspH is important in human biology, studies on its physiological roles have been limited by incomplete knowledge of its substrates. Here, we redefine the consensus sequence requirements for AspH-catalyzed EGFD hydroxylation based on combined analysis of proteomic mass spectrometric data and mass spectrometry-based assays with isolated AspH and peptide substrates. We provide cellular and biochemical evidence that the preferred site of EGFD hydroxylation is embedded within a disulfide-bridged macrocycle formed of 10 amino acid residues. This definition enabled the identification of previously unassigned hydroxylation sites in three EGFDs of human fibulins as AspH substrates. A non-EGFD containing protein, lymphocyte antigen-6/plasminogen activator urokinase receptor domain containing protein 6B (LYPD6B) was shown to be a substrate for isolated AspH, but we did not observe evidence for LYPD6B hydroxylation in cells. AspH-catalyzed hydroxylation of fibulins is of particular interest given their important roles in extracellular matrix dynamics. In conclusion, these results lead to a revision of the consensus substrate requirements for AspH and expand the range of observed and potential AspH-catalyzed hydroxylation in cells, which will enable future study of the biological roles of AspH.</p>","PeriodicalId":91947,"journal":{"name":"Procedia manufacturing","volume":"3 1","pages":"102129"},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293771/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82162115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Implementing Digitalised Lean Manufacturing Training in a UK Engine Manufacturing Centre During the SARS-CoV2 Pandemic of 2020","authors":"M.G. McKie , R. Jones , J. Miles , I.R. Jones","doi":"10.1016/j.promfg.2021.10.078","DOIUrl":"10.1016/j.promfg.2021.10.078","url":null,"abstract":"<div><p>This paper examines a novel way of training Lean Manufacturing Systems and Tools utilising an Industry 4.0 methodology during the SARS-COVID2 Pandemic of 2020. Currently, it is challenging for the Integrated Production Systems Team, responsible for carrying out training on the Lean principles, to undertake the training safely and without the risk of possible disease transmission. This is due to the usual close quarters training carried out in the Engine Manufacturing Centre. Schools, Colleges and Universities have adapted and utilised technology and moved to an Industry 4.0 digitalised approach to learning and development. This is therefore an opportunity for manufacturing to follow suit and create digitised solutions to training and development opportunities, to ensure that the employees within the manufacturing facility have adequate knowledge on the Lean principles.</p></div>","PeriodicalId":91947,"journal":{"name":"Procedia manufacturing","volume":"55 ","pages":"Pages 571-579"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565187/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39598505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Timothy No , Michael Gomez , Jaydeep Karandikar , Jarred Heigel , Ryan Copenhaver , Tony Schmitz
{"title":"Propagation of Johnson-Cook flow stress model uncertainty to milling force uncertainty using finite element analysis and time domain simulation","authors":"Timothy No , Michael Gomez , Jaydeep Karandikar , Jarred Heigel , Ryan Copenhaver , Tony Schmitz","doi":"10.1016/j.promfg.2021.06.025","DOIUrl":"10.1016/j.promfg.2021.06.025","url":null,"abstract":"<div><p>This paper describes the propagation of uncertainty in the parameters for a 6061-T6 aluminum Johnson-Cook flow stress model to, first, the uncertainty in the corresponding mechanistic cutting force model obtained by orthogonal cutting finite element simulation and, second, the milling force predicted by time domain simulation using the force model. The approach includes five key elements: 1) a literature review to identify the means and standard deviations for the 6061-T6 aluminum Johnson-Cook model parameters; 2) structured light scanning to measure an endmill’s cutting edge macro-geometry along the tool axis; 3) structured light scanning to identify the cutting edge cross-sectional rake and relief profiles for the same endmill; 4) orthogonal cutting finite element analysis to determine the mechanistic force model coefficients that relate the force components to chip area and width using the tool’s rake and relief profiles and random samples from the Johnson-Cook parameter distributions; and 5) time domain simulation with inputs that include the measured cutting edge macro-geometry, uncertain finite element-based force model, and measured structural dynamics. Distributions for milling force predictions are determined by Monte Carlo simulation and compared to in-process measurements for an indexable endmill-collet holder to demonstrate the approach. It is observed that 95% confidence intervals on the predicted forces bound the measured time-dependent force profile peaks in over half of the cases tested. It is also seen that the Johnson-Cook flow stress model-based force predictions performed as well as predictions based on a calibrated mechanistic force model.</p></div>","PeriodicalId":91947,"journal":{"name":"Procedia manufacturing","volume":"53 ","pages":"Pages 223-235"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.promfg.2021.06.025","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54983527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Estimation of cBN grinding wheel condition using image sensor","authors":"Eddie Taewan Lee, Zhaoyan Fan, Burak Sencer","doi":"10.1016/j.promfg.2021.06.031","DOIUrl":"10.1016/j.promfg.2021.06.031","url":null,"abstract":"<div><p>The tool condition used in machining process is generally determined by the wear status, which is an important factor of resulting in the machining efficiency of the manufacturing processes. This paper presents a method to estimate the tool condition of grinding wheel using an image sensor with machine learning techniques. Statistical features, mean, standard deviation, and entropy were selected from the simplified wear model. The selected features were extracted from the wheel surface images of an electroplated cubic Boron Nitride (cBN) wheel on a commercial CNC machine, and compared to the tool condition represented by the number of grinding passes. Finally, the statistical features were fused by machine learning techniques to estimate the wear condition of the grinding wheel. Results show a sufficient correspondence between the estimated and true tool condition with 0.9590 of the coefficient of determination <em>(R<sup>2</sup>)</em> based on support vector regression model.</p></div>","PeriodicalId":91947,"journal":{"name":"Procedia manufacturing","volume":"53 ","pages":"Pages 286-292"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.promfg.2021.06.031","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54983698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kandice S.B. Ribeiro , Fábio E. Mariani , Henrique T. Idogava , Gustavo C. da Silva , Zilda C. Silveira , Milton S.F. de Lima , Reginaldo T. Coelho
{"title":"Evaluation of laser polishing as post-processing of Inconel 625 produced by Directed Energy Deposition","authors":"Kandice S.B. Ribeiro , Fábio E. Mariani , Henrique T. Idogava , Gustavo C. da Silva , Zilda C. Silveira , Milton S.F. de Lima , Reginaldo T. Coelho","doi":"10.1016/j.promfg.2021.06.040","DOIUrl":"10.1016/j.promfg.2021.06.040","url":null,"abstract":"<div><p>As one of the Additive Manufacturing (AM) technologies, Directed Energy Deposition (DED) inherited common concerns from the AM concept, such as the layer discretization process, which brings about the staircase effect, and the complex thermal reheating cycles that occur due to the scanning strategies. In this regard, diversification in slicing strategies and the application of post-processing techniques arises as a feasible way to reduce defects and the usual poor surface finishing of DED parts. This study combines the non-planar slicing strategy as toolpath for laser polishing (LP) in DED parts, evaluating the influence of such post-processing for surface finishing, geometry and hardness of the Inconel 625 truncated pyramid built by DED. This geometry was built by using planar slicing and zigzag scanning strategy in BeAM M250 DED equipment. The non-planar coordinates of the LP were applied at an offset in the external profile of the pyramid with support of an open-source software Slic3R. The workpieces were built with laser power of 500 <em>W</em> delivered at the 800 <em>μm</em> spot diameter with scanning rate at 2000 <em>mm/min</em> and powder flow of 7.5 <em>g/min.</em> Laser polishing was performed considering three levels of energy density (9.38, 11.25 and 14.06 <em>J/mm<sup>2</sup>)</em> and the number of iterations (once, 3 and 5 times). Both, deposition and LP, were performed with local Argon gas shielding. Among the results, LP has shown to be a feasible post-processing technique to L-DED parts, which can improve surface finishing and shape, maintaining hardness. The energy spent LP causes the remelting of satellite particles and shown to be not enough to rearrange the microstructure. The non-planar slicing applied, as toolpath to the LP, comprises a new possibility allowing DED parts to have better results towards surface finishing with a clean and quick method of post-processing. This has shown to be beneficial to the efficiency of the post-processing stage by leading to a greater assertiveness of the process, less post-processing time and no waste of material.</p></div>","PeriodicalId":91947,"journal":{"name":"Procedia manufacturing","volume":"53 ","pages":"Pages 368-374"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.promfg.2021.06.040","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54983879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surface extraction from micro-computed tomography data for additive manufacturing","authors":"Weijun Shen , Xiao Zhang , Xuepeng Jiang , Li-Hsin Yeh , Zhan Zhang , Qing Li , Beiwen Li , Hantang Qin","doi":"10.1016/j.promfg.2021.06.057","DOIUrl":"10.1016/j.promfg.2021.06.057","url":null,"abstract":"<div><p>Surface topography and surface finish are two significant factors for evaluating the quality and dimensional accuracy of additive manufacturing (AM) parts. In general, compared with traditional subtraction and forming manufacturing techniques, the nature of the rough surface and the geometric complexity make the surface of AM parts \"another surface,\" and traditional methods such as coordinate machine measurement may not be applicable. Most research on surface extraction focuses on regular surfaces, such as flat, cylindrical, or spherical surfaces, but less has been done with irregular surfaces. This paper presented an approach for extracting irregular surfaces based on micro-computed tomography (μ-CT) data of AM parts. The extracted data sets were then compared with data sets obtained by a structured light system (SLS). Areal surface texture parameters, cloud comparison methods, and statistical methods were applied to evaluate the difference between the surface data obtained by the two systems. The results showed that the two surface data correlated well and confirmed the capability of the proposed method for surface extraction from irregular surfaces. This work will contribute to the further multi-sensor data fusion for metrology and provide valuable information for near-surface defects prediction with real-time <em>in-situ</em> metrology method in additive manufacturing.</p></div>","PeriodicalId":91947,"journal":{"name":"Procedia manufacturing","volume":"53 ","pages":"Pages 568-575"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.promfg.2021.06.057","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54984094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Applying Task-Oriented Safety Field Calibration in Human Robot Collaborative Systems","authors":"Cheng Zhu, Tian Yu, Qing Chang","doi":"10.1016/j.promfg.2021.06.067","DOIUrl":"10.1016/j.promfg.2021.06.067","url":null,"abstract":"<div><p>Effective and safe human-robot collaboration (HRC) in assembly requires a reasonable proximity between humans and robots. This paper considers an assembly scenario that humans and robots collaborate in a shared workspace, where safety is the most important issue. A dynamic safety field is defined for HRC to ensure safe collaboration and interaction between a human operator and a robot to achieve assembly tasks. The safety field can be adjusted and calibrated based on predicted assembly tasks. Utilizing the dynamically calibrated safety field, the robot movement will be obtained. The dynamic calibration of safety field for robot movement presents an alternative easier way for robot motion planning based on safety sense. Case studies are performed to demonstrate the effectiveness of the proposed dynamic safety field motion planning method.</p></div>","PeriodicalId":91947,"journal":{"name":"Procedia manufacturing","volume":"53 ","pages":"Pages 673-679"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.promfg.2021.06.067","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54984227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}