Journal of neurology and experimental neuroscience最新文献

{"title":"C1-C2 Joint Distraction and Fusion: A Robust Surgical Technique for Atlantoaxial Dislocation with Basilar Invagination","authors":"Tejesh Shavi, Sathwik Shetty, Bopanna Kumar, Praveen Ganigi, Khurram Khan","doi":"10.17756/jnen.2024-111","DOIUrl":"https://doi.org/10.17756/jnen.2024-111","url":null,"abstract":"Background: Atlantoaxial dislocation (AAD) and Basilar invagination (BI) are complex craniospinal alignment pathologies with significant clinical morbidity at presentation and a potential for life threatening complications. To realign the craniospinal complex optimally various strategies have been employed over the years ranging from, transoral odontoidectomy to sublaminar wire fixation and in situ screw fixation with significant morbidity and sub-optimal outcomes. This study focuses on our experience with the current treatment strategy of C1-C2 joint distraction and fusion, in managing this complex pathology. Purpose: To study the clinical and","PeriodicalId":91755,"journal":{"name":"Journal of neurology and experimental neuroscience","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140512305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intravascular Proliferation: A Case Report of Intravascular Large B Cell Lymphoma Arising within a Glioblastoma, IDH Wild Type","authors":"Jennifer Pfeiffer, William Oliver Humphrey, Alissa Ashley Thomas, John Charles DeWitt","doi":"10.17756/jnen.2023-109","DOIUrl":"https://doi.org/10.17756/jnen.2023-109","url":null,"abstract":"A synchronous multiple primary tumors is a second tumor that occurs within two months of identification of the first primary cancer. Collision tumors is the definition given to two synchronous tumors in the same organ whereby distinct borders between the two primary tumors are maintained. The occurrence of collision tumors is a very rare phenomenon. Here, we describe a case of an 82-year-old woman who presented with approximately one month’s duration of neurologic deficits. Magnetic resonance imaging (MRI) revealed a left parietal lobe lesion which was radiographically concerning for a high-grade glioma. Following surgical resection microscopic examination of the mass revealed high-grade glioma with synchronous malignant lymphoma involving tumor vasculature, consistent with a collision of glioblastoma, IDH-wildtype, and intravascular large B cell lymphoma. To our knowledge, this represents the first reported case of a collision tumor involving these two entities.","PeriodicalId":91755,"journal":{"name":"Journal of neurology and experimental neuroscience","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139279852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Report on the 8th Neurological Disorders Summit (NDS-2023)","authors":"","doi":"10.17756/jnen.2023-108","DOIUrl":"https://doi.org/10.17756/jnen.2023-108","url":null,"abstract":"","PeriodicalId":91755,"journal":{"name":"Journal of neurology and experimental neuroscience","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67651140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proceedings of the 8th Neurological Disorders Summit (NDS-2023)","authors":"L. Ju, Jiepei Zhu, T. Morey, N. Gravenstein, C. Seubert, T. Vasilopoulos, A. Martynyuk, Chisato Kinoshita, K. Aoyama, T. Nakaki, E. Spinazzi, Mychael Delgardo, Andrés Pascual-Leones, Colby T Joncas, G. Mandigo, S. Lavine, J. Grinband, E. Sander, I. Khaliulin, Maryam Kartawy, H. Amal, Juliana Condoleo, Hu Wang, C. K. Bullen, Xiaoli Rong, Hao Fang, Senthilkumar S. Karuppagounder, Yongxing Gao, T. Dawson, V. Dawson, Jin-chong Xu, Jong-Hyun Son, Amanda K. Gerenza, Gabrielle M. Bingener, J. Bonkowsky, Kharon Grimmet, L. Gangwani, LouAnne E. Boyd, S. Upreti, Madhumita P. Ghosh, M. Podda, Saviana Antonella, Barbati, Chiara D'Amelio, Ida Nifo Sarrapocchiello, S. Fusco, Claudio Grassi, Matea Drlje, Sara Trnski, Andrija Štajduhar, Mihaela Bobić-Rasonja, Davide di Cenco, Eugene Kim, Eilidh MacNicol, K. Ilić, D. Cash, S. Škokić, N. Milošević, M. Youdim, Ofira Einstein Presenter, A. Katz, T. Ben-Hur, R. Howell, M. Lloyd-Puryear, Rabea Iris Pantelatos, K. Moen, A. Vik, T. Skandsen, René Daniel, S. Efrati, A. Hadanny, S","doi":"10.17756/jnen.2023-suppl1","DOIUrl":"https://doi.org/10.17756/jnen.2023-suppl1","url":null,"abstract":"Introduction: Preexisting neurodegenerative diseases, perioperative stress, and inflammation play an essential role in accelerated neurocognitive decline after general anesthesia (GA) and surgery, termed perioperative neurocognitive disorder (PND). PND is an important public health problem potentially affecting millions of patients. Because neurodegenerative diseases pre-vail and worsen with age, PND is most readily detectable and studied in the aging population. Traumatic brain injury (TBI), with >50 million cases/year, is a dominant cause of disability in young adults. Similar to PND, the pathophysiology of TBI involves lasting dysregulation of stress response systems, neuroinflammation, and cognitive decline. Patients with a history of TBI may also require GA/surgery or sedation to treat conditions unrelated to TBI, or injuries sustained at the time of TBI. Here we tested whether the effects of GA/surgery, TBI, and subsequent repeated exposure to the general anesthetic sevoflurane (SEVO) interact to induce neurological and neuroendocrine abnormalities in the exposed young adult male rats (an animal model of PND) and/or in their future offspring (intergenerational PND). Methods: All animal procedures were approved by IACUC. Sprague-Dawley","PeriodicalId":91755,"journal":{"name":"Journal of neurology and experimental neuroscience","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67651220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Amyotrophic Lateral Sclerosis: Therapeutic Progress in Neurology Practice","authors":"","doi":"10.17756/jnen.2023-100","DOIUrl":"https://doi.org/10.17756/jnen.2023-100","url":null,"abstract":"","PeriodicalId":91755,"journal":{"name":"Journal of neurology and experimental neuroscience","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67650803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Individualized Intervention, Based on the Feldenkrais Method, for Multiple Sclerosis Symptoms: The Neuroplasticity Scale Assessment","authors":"","doi":"10.17756/jnen.2023-102","DOIUrl":"https://doi.org/10.17756/jnen.2023-102","url":null,"abstract":"","PeriodicalId":91755,"journal":{"name":"Journal of neurology and experimental neuroscience","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67650956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypovitaminosis D in Painful Peripheral Neuropathy","authors":"Jin Jun Luo, Nae J. Dun","doi":"10.17756/jnen.2023-107","DOIUrl":"https://doi.org/10.17756/jnen.2023-107","url":null,"abstract":"Vitamin D is an essential vitamin necessary for maintaining proper bone structure by regulating calcium-phosphorus metabolism in the body. Vitamin D, as a hormone, also has effects on the nervous system. Peripheral neuropathy (PN) comprises a group of disorders involving the peripheral nervous system, which includes sensory, motor, and autonomic nerves. PN manifests as various symptoms, such as pain, numbness, and muscle weakness, alone or in combination. PN is caused by a wide variety of etiologies. Accumulating evidence from clinical and laboratory studies shows that hypovitaminosis-D may be a potentially independent risk factor for painful PN. Administering vitamin D to patients with hypovitaminosis-D alleviates their neuropathic symptoms. In this article, we review up-to-date clinical observations on hypovitaminosis-D","PeriodicalId":91755,"journal":{"name":"Journal of neurology and experimental neuroscience","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67650976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"If Light Could Help: The Use of Transcranial Photobiomodulation in Parkinson’s Disease. A Controlled Clinical Study","authors":"Federica Peci, R. Pica, S. Peci, Cerebro Company","doi":"10.17756/jnen.2023-105","DOIUrl":"https://doi.org/10.17756/jnen.2023-105","url":null,"abstract":"Objective: The aim of this study is to investigate whether a 4-week phys-iotherapeutic rehabilitation combined with transcranial photobiomodulation (tPBM) treatment is more effective than the only motor rehabilitation and if the improvement persists at 1-month follow-up. Methods: We investigated 40 Parkinson’s disease (PD) patients, divided into two different groups: a control group that underwent only physiotherapeutic rehabilitation and the experimental one that underwent physiotherapeutic rehabilitation combined with PBM treatment. Outcome measures were UPDRS Part I, Part II and Part III. Patients were evaluated at admission, at the end of 4-week treatment and at 1 month follow up. Results: All outcome measures improved for each group, but significantly improved at the end of treatment for the experimental group not only related to motor symptoms but also to everyday struggle. Conclusion: Our results demonstrate that the combination of PBM treat-ment with physiotherapeutic rehabilitation was effective in improving motor symptoms in PD patients and the improvement in balance, gait and tremor were partially maintained after 1 month.","PeriodicalId":91755,"journal":{"name":"Journal of neurology and experimental neuroscience","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67650741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primitive Reflex Integration and Reading Achievement in the Classroom","authors":"","doi":"10.17756/jnen.2023-103","DOIUrl":"https://doi.org/10.17756/jnen.2023-103","url":null,"abstract":"","PeriodicalId":91755,"journal":{"name":"Journal of neurology and experimental neuroscience","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67651032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disease Modification Therapy with Anti-Soluble Aβ Protofibril Antibody for Alzheimer Disease","authors":"","doi":"10.17756/jnen.2023-101","DOIUrl":"https://doi.org/10.17756/jnen.2023-101","url":null,"abstract":"","PeriodicalId":91755,"journal":{"name":"Journal of neurology and experimental neuroscience","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67650905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}