Journal of gynecology research最新文献

Liquid-Based Cytology Compared to Conventional Cytology for Diagnosis of Cervical Intraepithelial Neoplasia: A Single-Center Experience 液基细胞学与常规细胞学诊断宫颈上皮内瘤变的比较:单中心经验

Journal of gynecology research Pub Date : 2018-09-01 DOI: 10.15744/2454-3284.4.206

L. Flores-Hernández, Ramírez-Uribe Rd, Villegas-González Lf, Serrano-Arévalo Ml, Cordoba-Gonzalez, Barquet-Muñoz Sa

引用次数: 0

Determinants of Medication Adherence in Nausea and Vomiting of Pregnancy 妊娠期恶心呕吐药物依从性的决定因素

Journal of gynecology research Pub Date : 2018-09-01 DOI: 10.15744/2454-3284.4.201

I. I, Cohen R, Berkovitch M, Koren G

引用次数: 0

Positive Efficiency of Combine Immunotherapy in Immunocompromised Girls with Recurrent Nonspecific Chronic Vulvovaginitis 联合免疫治疗复发性非特异性慢性外阴阴道炎的疗效观察

Journal of gynecology research Pub Date : 2018-09-01 DOI: 10.15744/2454-3284.4.207

Nesterova Iv, Kovaleva Sv, Chudilova Ga, Lomtatidze Lv, Krutova Va, Shuvalov An, Malinovskaya Vv

{"title":"Positive Efficiency of Combine Immunotherapy in Immunocompromised Girls with Recurrent Nonspecific Chronic Vulvovaginitis","authors":"Nesterova Iv, Kovaleva Sv, Chudilova Ga, Lomtatidze Lv, Krutova Va, Shuvalov An, Malinovskaya Vv","doi":"10.15744/2454-3284.4.207","DOIUrl":"https://doi.org/10.15744/2454-3284.4.207","url":null,"abstract":"Nonspecific chronic vulvovaginites (NCVV) are a frequent clinical sign of immune deficiency, especially in young girls. The established problems with the functioning of various parts of the immune system (IS) in this pathology dictate the need to include immunomodulatory therapy into the complex. The developed program of combined immunotherapy for immunocompromised girls allows reducing the severity and duration of exacerbation of NCVV, their frequency against the background of a significant reduction in ARVI incidence. Positive clinical effects were observed with underlying restoration in IS functioning. A protective effect was obtained (observation in a catamnesis for 1 year): the duration of a clinically safe period increased from 6 to 11-11.5 months per year. Introduction Vulvovaginitis takes the first place in the structure of gynaecological disorders in girls of primary school age and preschool age, with the peak share at the age of 2-7 years old. Acute and chronic genital inflammations in childhood may later cause serious infections and inflammations in women of various ages and result in reproductive disorders in women of childbearing age. Therefore tackling the challenge of protecting the reproductive health of children and teenagers, preventing and treating gynaecological disorders in children is a burning issue; it is of huge practical significance and of a certain interest both for scientists and practitioners.","PeriodicalId":91315,"journal":{"name":"Journal of gynecology research","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76895444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of Bilirubin and Albumin in Cord Blood as Predictors for Neonatal Hyperbilirubinemia 脐带血中胆红素和白蛋白作为新生儿高胆红素血症预测因子的作用

Journal of gynecology research Pub Date : 2018-09-01 DOI: 10.15744/2454-3284.4.208

M. Alalfy, A. E. lithy, Z. Ezzeldin, Y. Mansi, A. Hamed, Marwa Mostafa, A. Adel

{"title":"Role of Bilirubin and Albumin in Cord Blood as Predictors for Neonatal Hyperbilirubinemia","authors":"M. Alalfy, A. E. lithy, Z. Ezzeldin, Y. Mansi, A. Hamed, Marwa Mostafa, A. Adel","doi":"10.15744/2454-3284.4.208","DOIUrl":"https://doi.org/10.15744/2454-3284.4.208","url":null,"abstract":"Role of Bilirubin and Albumin in Cord Blood as Predictors for Neonatal Hyperbilirubinemia Mahmoud Alalfy*1, Ahmed el lithy2, Zahraa Mohamed EzzEldin3, Yasmeen Amr Mansi3, Alaa Hamed4, Marwa basher Mostafa5 and Ahmed Adel6 1Lecturer, Researcher, Reproductive health and family planning department, National Research Centre, Egypt, and The senior Fellow in cairo fetal medicine unit, Egypt and Consultant OB/Gyn, Aljazeerah Hospital, Egypt 2Assistant professor Obstetrics and Gynecology, Kasralainy faculty of medicine, Cairo university, Egypt 3Professor of Pediatrics & NeonatologyFaculty of Medicine, Cairo University, Egypt 4Lecturer of obstetrics and Gynecology, Alazhar faculty of medicine, Alazhar university 5Specialist of Obstetrics Pediatrics and neonatology, Egypt 6Assistant Researcher, Child Health department, National Research Centre, Egypt *Corresponding author: Mahmoud Alalfy, PhD. Lecturer, Researcher, Reproductive Health and family planning department, national Research Centre, Egypt, and Consultant OB/Gyn, Aljazeerah Hospital, Egypt, Tel: +201002611058, E-mail: mahmoudalalfy@ymail.com","PeriodicalId":91315,"journal":{"name":"Journal of gynecology research","volume":"79 5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83440101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Hirsutism will be not Considered as Sign of Progressive Disease after Autologous Transplant in POEMS Syndrome 多毛症不被认为是POEMS综合征自体移植后疾病进展的标志

Journal of gynecology research Pub Date : 2018-09-01 DOI: 10.15744/2454-3284.4.203

F. Sorà, I. Innocenti, P. Chiusolo, F. Autore, Rotarescu Ca, M. Luigetti, S. Sica, L. Laurenti

引用次数: 0

Impact of Inverted Interrupted Skin Suturing Versus Continous Suturing in Episiotomy on Postpartum Pain in Primigravida 会阴切开术中连续缝合与倒置间断缝合对初产妇产后疼痛的影响

Journal of gynecology research Pub Date : 2018-09-01 DOI: 10.15744/2454-3284.4.205

M. Alalfy, Amr Abbassy, Yossra Lasheen

引用次数: 1

Ultrasound Criteria for Expecting Mode of Delivery after Induction of Labour in Primigravida with Postdates 初产妇产后引产的超声诊断标准

Journal of gynecology research Pub Date : 2018-09-01 DOI: 10.15744/2454-3284.4.204

M. Alalfy, Ahmed M. Hassan, M. Saleh

引用次数: 0

A Rare Recurrence of an Immature Teratoma: A Case Report 罕见的未成熟畸胎瘤复发1例报告

Journal of gynecology research Pub Date : 2018-09-01 DOI: 10.15744/2454-3284.4.202

Huang J, Z. Z, S. N, Yao S, L. D

引用次数: 0

Molecular Mechanism Linking BRCA1 Dysfunction to High Grade Serous Epithelial Ovarian Cancers with Peritoneal Permeability and Ascites. BRCA1功能障碍与高级别浆液性上皮性卵巢癌伴腹膜通透性和腹水的分子机制

Journal of gynecology research Pub Date : 2015-04-24 DOI: 10.15744/2454-3284.1.103

A. Desai, J. Xu, K. Aysola, O. Akinbobuyi, M. White, V. Reddy, J. Okoli, C. Clark, E. Partridge, E. Childs, D. Beech, M. Rice, E. Reddy, V. Rao

{"title":"Molecular Mechanism Linking BRCA1 Dysfunction to High Grade Serous Epithelial Ovarian Cancers with Peritoneal Permeability and Ascites.","authors":"A. Desai, J. Xu, K. Aysola, O. Akinbobuyi, M. White, V. Reddy, J. Okoli, C. Clark, E. Partridge, E. Childs, D. Beech, M. Rice, E. Reddy, V. Rao","doi":"10.15744/2454-3284.1.103","DOIUrl":"https://doi.org/10.15744/2454-3284.1.103","url":null,"abstract":"Ovarian cancer constitutes the second most common gynecological cancer with a five-year survival rate of 40%. Among the various histotypes associated with hereditary ovarian cancer, high-grade serous epithelial ovarian carcinoma (HGSEOC) is the most predominant and women with inherited mutations in BRCA1 have a lifetime risk of 40-60%. HGSEOC is a challenge for clinical oncologists, due to late presentation of patient, diagnosis and high rate of relapse. Ovarian tumors have a wide range of clinical presentations including development of ascites as a result of deregulated endothelial function thereby causing increased vascular permeability of peritoneal vessels. The molecular mechanisms remain elusive. Studies have shown that fallopian tube cancers develop in women with BRCA1 gene mutations more often than previously suspected. Recent studies suggest that many primary peritoneal cancers and some high-grade serous epithelial ovarian carcinomas actually start in the fallopian tubes. In this article we have addressed the molecular pathway of a recently identified potential biomarker Ubc9 whose deregulated expression due to BRCA1 dysfunction can result in HGSEOC with peritoneal permeability and formation of ascites. We also discuss the role of downstream targets Caveolin-1 and Vascular Endothelial Growth Factor (VEGF) in the pathogenesis of ascites in ovarian carcinomas. Finally we hypothesize a signaling axis between Ubc9 over expression, loss of Caveolin-1 and induction of VEGF in BRCA1 mutant HGSEOC cells. We suggest that Ubc9-mediated stimulation of VEGF as a novel mechanism underlying ovarian cancer aggressiveness and ascites formation. Agents that target Ubc9 and VEGF signaling may represent a novel therapeutic strategy to impede peritoneal growth and spread of HGSEOC.","PeriodicalId":91315,"journal":{"name":"Journal of gynecology research","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76635074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6