Liquid-Based Cytology Compared to Conventional Cytology for Diagnosis of Cervical Intraepithelial Neoplasia: A Single-Center Experience

Abstract

Conclusion: Considering no statistically differences in the results and the outlay of LBC, implementation of LBC should be used for molecular-based detection and genotyping when human papillomavirus may offer additional benefits when screening for cervical carcinoma. Introduction: Cervical carcinoma is the fourth most common gynecologic cancer. Screening assays that include the conventional cytology (CC) have a sensitivity and specificity far from optimal; however, liquid-based cytology (LBC) may overcome some limitations. The objective is to compare the screening accuracy of LBC and CC in individuals suspected of having precancerous lesions.