Kyoung-Yeon Hwang, Young-In Yoon, Shin Hwang, Tae-Yong Ha, Chul-Soo Ahn, Ki-Hun Kim, Deok-Bog Moon, Gi-Won Song, Dong-Hwan Jung, Young-Joo Lee, Kwang-Min Park, Sung-Gyu Lee
{"title":"Survival analysis following resection of AJCC stage III gallbladder carcinoma based on different combinations of T and N stages.","authors":"Kyoung-Yeon Hwang, Young-In Yoon, Shin Hwang, Tae-Yong Ha, Chul-Soo Ahn, Ki-Hun Kim, Deok-Bog Moon, Gi-Won Song, Dong-Hwan Jung, Young-Joo Lee, Kwang-Min Park, Sung-Gyu Lee","doi":"10.14701/kjhbps.2015.19.1.11","DOIUrl":"https://doi.org/10.14701/kjhbps.2015.19.1.11","url":null,"abstract":"<p><strong>Backgrounds/aims: </strong>According to 7th AJCC TNM staging system, gallbladder carcinoma (GBC) with lymph node (LN) metastasis is classified as N1 or N2; thus making the stage IIIB (N1) or IVB (N2). Stage IIIB consists of N1 status with wide coverage of T1-3, but T3N1 group often showed poorer outcomes than T1-2N1 groups. This study intended to assess post-resection prognosis of T3N1 versus other stage III subgroups.</p><p><strong>Methods: </strong>We selected 103 patients from our institutional database of GBC who underwent R0 resection between July 1996 and June 2009 and whose GBC was confined to stage T3N0, T1-3N1 or T1-3N2. These patients were stratified into five groups, namely, T3N0 (n=26), T1N1 (n=13), T2N1 (n=35), T3N1 (n=20) and T1-3N2 (n=9), and were followed for ≥5 years or until death.</p><p><strong>Results: </strong>Surgical procedures were minor liver resection (n=53), minor liver resection with bile duct resection (n=23), major liver resection (n=12), major liver resection with bile duct resection (n=5), and hepatopancreatoduodenectomy (n=12). Mean follow-up period was 57.2±68.5 months. Overall 5-year survival rate based on all-cause death and cancer-associated death, respectively, was 57.7% and 60.6% in T3N0, 15.4% and 15.4% in T1N1 (n=13), 28.6% and 28.6% in T2N1 (n=35), 5.0% and 5.7% in T3N1 (n=20), and 22.2% and 22.2% in T1-3N2. The survival outcome of T3N1 group was the poorest among the four stage III groups and was comparable to that of stage IVB (p=0.53).</p><p><strong>Conclusions: </strong>The prognosis of T3N1 GBC is unusually poor even after R0 resection, thus we suggest extensive LN dissection may be necessary in patients with T3 tumors for accurate prognostic evaluation and radical removal of potential nodal micrometastasis. Further validation of this result is necessary in large patient populations from multiple centers.</p>","PeriodicalId":91136,"journal":{"name":"Korean journal of hepato-biliary-pancreatic surgery","volume":"19 1","pages":"11-6"},"PeriodicalIF":0.0,"publicationDate":"2015-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.14701/kjhbps.2015.19.1.11","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33888310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jae Hyun Kwon, Song Cheol Kim, Ki-Byung Song, Jae Hoon Lee, Dae Wook Hwang, Kwang-Min Park, Young-Joo Lee
{"title":"Surgical outcomes of multifocal branch duct intraductal papillary mucinous neoplasms of pancreas.","authors":"Jae Hyun Kwon, Song Cheol Kim, Ki-Byung Song, Jae Hoon Lee, Dae Wook Hwang, Kwang-Min Park, Young-Joo Lee","doi":"10.14701/kjhbps.2014.18.4.152","DOIUrl":"https://doi.org/10.14701/kjhbps.2014.18.4.152","url":null,"abstract":"<p><strong>Backgrounds/aims: </strong>Appropriate management for multifocal branch duct type intraductal papillary mucinous neoplasms (BD-IPMNs) of the pancreas is still controversial. This study was intended to reveal surgical outcomes of surgical resection for multifocal BD-IPMNs, with BD-IPMNs in the remnant pancreas.</p><p><strong>Methods: </strong>Between January 1995 and December 2013, 699 patients underwent the pancreatic resection due to IPMN of pancreas in our institution. Among them, 37 patients showed multifocal BD-IPMNs. After excluding patients who had BD-IPMNs completely resected, medical records of 22 patients with remained BD-IPMNs in the remnant pancreas were retrospectively reviewed.</p><p><strong>Results: </strong>Mean patient age was 65±6.4 years. Types of surgery included central pancreatectomy (n=1), distal pancreatectomy (n=14), and standard pylorus-preserving pancreaticoduodenectomy (n=7). Specimen pathology showed that IPMN was either at low/intermediate-grade dysplasia (n=17) or at high-grade dysplasia (n=2). Three patients had IPMN associated with invasive carcinoma. Their mean follow-up period was 40.4 months. During follow-up, one mortality occurred 35.2 months after the operation which was not associated with IPMN. There was no clinically significant disease progression or recurrence of IPMN in the remnant pancreas during the follow-up period.</p><p><strong>Conclusions: </strong>Our results support that we can safely preserve the pancreas parenchyma with multifocal BD-IPMNs. Benign-looking multifocal BD-IPMNs in the remnant pancreas do not affect the survival of patients.</p>","PeriodicalId":91136,"journal":{"name":"Korean journal of hepato-biliary-pancreatic surgery","volume":"18 4","pages":"152-8"},"PeriodicalIF":0.0,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.14701/kjhbps.2014.18.4.152","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34272093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joo Hwa Kwak, Jin Seok Heo, Jin Young Park, Dong Wook Choi, Seong Ho Choi, Hui Song Lee
{"title":"Outcomes of pancreaticoduodenectomy in patients with metastatic cancer.","authors":"Joo Hwa Kwak, Jin Seok Heo, Jin Young Park, Dong Wook Choi, Seong Ho Choi, Hui Song Lee","doi":"10.14701/kjhbps.2014.18.4.147","DOIUrl":"https://doi.org/10.14701/kjhbps.2014.18.4.147","url":null,"abstract":"<p><strong>Backgrounds/aims: </strong>Metastatic cancer of pancreas is rarely resectable. Pancreaticoduodenectomy carries high risks of morbidities and mortalities that it is rarely performed for metastatic cancer. In this study, the clinical features and outcomes of metastatic cancer of pancreas after pancreaticoduodenectomy were reviewed and analyzed.</p><p><strong>Methods: </strong>We retrospectively reviewed patients who underwent pancreaticoduodectomy from January 2000 to December 2012 in Samsung Medical Center. A total of 1045 patients were enrolled in this study. Inclusion criteria were patients who had metachronous lesions with tumors histologically confirmed as metastatic cancer. However, patients with tumors directly invaded pancreas head, bile duct, and duodenum were excluded from this study. Finally, a total of 12 patients who underwent pancreaticoduodenectomy due to metastatic cancer were used in this study. Clinicopathologic features and perioperative data of these 12 patients were retrospectively reviewed.</p><p><strong>Results: </strong>The 12 patients included 6 females and 6 males who had metastatic lesions at pancreas head, duodenum 2nd-3rd portion, and distal common bile duct. The mean age of patients was 62.7 years old at the time of pancreaticoduodenectomy. The interval between the time of the first operation for primary cancer and pancreaticoduodenectomy was 67.7 months. The mean survival time after pancreaticoduodectomy was 38.6 months (range, 12 to 119 months). There was no fatal complication after the surgery.</p><p><strong>Conclusions: </strong>Pancreaticoduodenectomy is becoming a safer procedure with less complication compared to the past. Patients with recurrent metastatic cancer should be considered for metastectomy if tumors are resectable. Pancreaticoduodenectomy should be considered as one main treatment for patients with recurrent metastatic cancer to offer a chance of long-term survival in selected patients.</p>","PeriodicalId":91136,"journal":{"name":"Korean journal of hepato-biliary-pancreatic surgery","volume":"18 4","pages":"147-51"},"PeriodicalIF":0.0,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.14701/kjhbps.2014.18.4.147","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34272092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Duhwan Yun, Seokhwan Kim, Insang Song, Kwangsik Chun
{"title":"Comparative analysis of Laparoscopic versus open surgical radiofrequency ablation for malignant liver tumors.","authors":"Duhwan Yun, Seokhwan Kim, Insang Song, Kwangsik Chun","doi":"10.14701/kjhbps.2014.18.4.122","DOIUrl":"https://doi.org/10.14701/kjhbps.2014.18.4.122","url":null,"abstract":"<p><strong>Backgrounds/aims: </strong>This study aims to evaluate the comparative effectiveness of two surgical approaches on the treatment outcomes of radiofrequency ablation (RFA) for malignant liver tumors.</p><p><strong>Methods: </strong>Fifty-seven patients with malignant liver tumors, hepatocellular carcinoma, cholangiocarcinoma and liver metastases, who were candidates for RFA, underwent laparoscopic or open surgical treatments.</p><p><strong>Results: </strong>The patients' characteristics were comparable in the two groups that received open (n=33, 57.9%) and laparoscopic (n=24, 42.1%) surgical treatments. There were no statistically significant differences between the two groups in terms of recurrence rate (p=0.337) and overall survival (p=0.423). However, patients in the laparoscopic RFA group had significantly shorter hospital stay (14.1 vs. 5.9 days, p<0.05) and experienced fewer complications (Grade I: 62.5% vs. 26.3%, p=0.102).</p><p><strong>Conclusions: </strong>Laparoscopic RFA can be performed for malignant liver tumors with lower morbidity rates, less invasiveness and lower expense compared to open surgical approach.</p>","PeriodicalId":91136,"journal":{"name":"Korean journal of hepato-biliary-pancreatic surgery","volume":"18 4","pages":"122-8"},"PeriodicalIF":0.0,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.14701/kjhbps.2014.18.4.122","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34272089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bong Jun Kwak, Song Cheol Kim, Ki-Byung Song, Jae Hoon Lee, Dae Wook Hwang, Kwang-Min Park, Young-Joo Lee
{"title":"Prognostic factors associated with early mortality after surgical resection for pancreatic adenocarcinoma.","authors":"Bong Jun Kwak, Song Cheol Kim, Ki-Byung Song, Jae Hoon Lee, Dae Wook Hwang, Kwang-Min Park, Young-Joo Lee","doi":"10.14701/kjhbps.2014.18.4.138","DOIUrl":"https://doi.org/10.14701/kjhbps.2014.18.4.138","url":null,"abstract":"<p><strong>Backgrounds/aims: </strong>Identifying pancreatic cancer patients at high risk of early mortality following surgical resection for pancreatic cancer is important to make optimal treatment decisions in multidisciplinary setting. The purpose of this study was to identify the factors related to early mortality in patients who underwent pancreatic resection for pancreatic adenocarcinoma.</p><p><strong>Methods: </strong>We reviewed our institution's experience with all consecutive patients who underwent pancreatectomy for pancreatic adenocarcinoma from January 2000 to December 2010. One thousand patients were eligible for our study. Fifty-three patients who did not meet the study criteria were excluded. Based on 12 months after surgery, patients were divided into early mortality group or the remaining group. We performed logistic regression analysis to identify predictors of early mortality.</p><p><strong>Results: </strong>Among 947 patients who met our study criteria, 302 (31.9%) early mortality (defined as experiencing death within 12 months after surgery) occurred. Multivariate analysis revealed that patient age and surgery time period were statistically significant predictors of early mortality within six months after surgery. Poorly differentiated tumor and adjuvant chemotherapy were statistically significant predictors of early mortality within 12 months after surgery. Total pancreatectomy and lymphovascular invasion were significant (p<0.05) prognostic factors of early mortality within 6 or 12 months after surgery.</p><p><strong>Conclusions: </strong>We suggest followings to avoid early mortality after pancreatic resection: patients with multiple risk factors related to early mortality after pancreatectomy should be considered for alternative treatment; patient's general condition and surgical technique improvement are important; and adjuvant therapy should be taken into consideration.</p>","PeriodicalId":91136,"journal":{"name":"Korean journal of hepato-biliary-pancreatic surgery","volume":"18 4","pages":"138-46"},"PeriodicalIF":0.0,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.14701/kjhbps.2014.18.4.138","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34272091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Feasibility of laparoscopic liver resection for giant hemangioma of greater than 6 cm in diameter.","authors":"In Sung Kim, Choon Hyuck David Kwon","doi":"10.14701/kjhbps.2014.18.4.118","DOIUrl":"https://doi.org/10.14701/kjhbps.2014.18.4.118","url":null,"abstract":"<p><strong>Backgrounds/aims: </strong>Liver hemangioma, the most common benign liver tumor, can be safely managed by clinical observation. However, surgical treatment should be considered in a subset of patients with giant hemangioma with abdominal symptoms. We reviewed the feasibility of total laparoscopic liver resection for giant hemangioma of >6 cm in diameter.</p><p><strong>Methods: </strong>Nine consecutive patients who underwent total laparoscopic liver resection for giant hemangioma between August 2008 to December 2012 were included in this study. Medical records were retrospectively reviewed for demographic data, laboratory findings, and perioperative results.</p><p><strong>Results: </strong>The median age of patients was 36 yrs (range, 31-63). Eight females and 1 male were included in the study. The median size of hemangioma was 11 cm in diameter (range, 6-18) and 5 patients had a hemangioma >10 cm. Indications for surgical treatments were abdominal symptoms in 4 patients, increased size in 5 patients, and uncertain diagnosis in 1 patient. The median operation time was 522 minutes for right hepatectomy, 220 minutes for left lateral sectionectomy, and 90 minutes for wedge resection. The median estimated blood loss was 400 ml (range, 50-900). There was no postoperative morbidity, including Clanvien-Dindo grade I.</p><p><strong>Conclusions: </strong>The resection of giant hemangioma demands meticulous surgical technique due to high vascularity and the concomitant risk of intraoperative hemorrhage. Laparoscopic liver resection is feasible with minimal operative complication. Therefore, laparoscopic liver resection can be considered as an option for surgical treatment for giant hemangioma.</p>","PeriodicalId":91136,"journal":{"name":"Korean journal of hepato-biliary-pancreatic surgery","volume":"18 4","pages":"118-21"},"PeriodicalIF":0.0,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.14701/kjhbps.2014.18.4.118","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34272088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kui Sun Choi, Dong-Sik Kim, Sung Won Jung, Young-Dong Yu, Sung Ock Suh
{"title":"Influence of metabolic and other clinicopathologic factors on the prognosis of patients with hepatocellular carcinoma undergoing hepatic resection.","authors":"Kui Sun Choi, Dong-Sik Kim, Sung Won Jung, Young-Dong Yu, Sung Ock Suh","doi":"10.14701/kjhbps.2014.18.4.105","DOIUrl":"https://doi.org/10.14701/kjhbps.2014.18.4.105","url":null,"abstract":"<p><strong>Backgrounds/aims: </strong>The prognosis of hepatic resection for hepatocellular carcinoma (HCC) in patients with cirrhosis is worse than in those without cirrhosis. In Korea, the hepatitis B virus prevalence rate is higher than in other countries. Therefore, we investigated patients' clinicopathologic and metabolic factors that affect the postoperative outcomes of hepatic resection for HCC in our hospital in Korea.</p><p><strong>Methods: </strong>From August 2000 to December 2012, 171 HCC patients underwent hepatic resections at our institution. Two operative mortality cases and two short-term follow up cases were excluded. Data was collected from a retrospective chart review. There were 133 males (79.6%) and 34 females (20.3%), with a mean age of 58.2±10.2 years (range, 22-81 years), and the relationship between clinicopathologic and metabolic factors and the prognosis of patients with HCC undergoing hepatic resection were evaluated by univariate and multivariate analysis.</p><p><strong>Results: </strong>Hypertension, major surgery, perioperative transfusion, resection with radiofrequency ablation (RFA) or cryoablation, and resection margin were risk factors for overall survival, and hypertension, albumin, resection with RFA or cryoablation, perioperative transfusion, and tumor size were risk factors for disease-free survival.</p><p><strong>Conclusions: </strong>We found that hypertension, perioperative transfusion, and resection with RFA or cryoablation were risk factors for both disease-free and overall survival after hepatic resection in HCC patients. Further study is required to clarify the influence of metabolic and other clinicopathologic factors on the prognosis of HCC.</p>","PeriodicalId":91136,"journal":{"name":"Korean journal of hepato-biliary-pancreatic surgery","volume":"18 4","pages":"105-11"},"PeriodicalIF":0.0,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.14701/kjhbps.2014.18.4.105","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34271085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juhong Park, Seokhwan Kim, Insang Song, Kwangsik Chun
{"title":"Experience of laparoscopic liver resection for various liver diseases.","authors":"Juhong Park, Seokhwan Kim, Insang Song, Kwangsik Chun","doi":"10.14701/kjhbps.2014.18.4.112","DOIUrl":"https://doi.org/10.14701/kjhbps.2014.18.4.112","url":null,"abstract":"<p><strong>Backgrounds/aims: </strong>We present our experience of laparoscopic liver resection for various liver diseases.</p><p><strong>Methods: </strong>From April 2008 to August 2012 in Chungnam National University, 68 of 253 liver resections were performed laparoscopically. During the first year, laparoscopy-assisted liver resection was mainly performed and subsequently totally laparoscopic liver resection was the main operative type. Surgery type for treatment purposes was decided preoperatively. Clinical data were collected retrospectively and analyzed.</p><p><strong>Results: </strong>Preoperatively, 43 patients (63.2%) were diagnosed with benign disease, 19 patients (27.9%) were malignant liver tumors and 6 patients (8.8%) were indeterminate liver tumor but favorable towards malignancy. Anatomical major liver resection was performed in 58 cases (85.3%) and 10 cases (14.7%) were non-anatomical resection. Left hemihepatectomy was performed in 38 cases (55.8%) followed by left lateral sectionectomy in 18 cases (26.5%), and segment IV and IVa segmentectomy, were each in 1 case. Mean operation time was 235.0 minutes (range, 60-470) and 14 patients (18.6%) had intraoperative transfusion. Mean postoperative hospital stay was 10.2 days (range, 4-32). Mean operation time of laparoscopy-assisted left lobectomy was 317 minutes and totally laparoscopic left lobectomy was 281 minutes, but there was no significant statistical difference between these two operation types. There were 11 episodes of postoperative complications in 8 patients. There was no mortality after laparoscopic liver resection.</p><p><strong>Conclusions: </strong>We concluded that laparoscopic liver resection is a feasible operation, but needs to be carefully conducted in malignant tumors.</p>","PeriodicalId":91136,"journal":{"name":"Korean journal of hepato-biliary-pancreatic surgery","volume":"18 4","pages":"112-7"},"PeriodicalIF":0.0,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.14701/kjhbps.2014.18.4.112","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34271086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eun Kyung Hong, Kun Kuk Kim, Jung Nam Lee, Woon Kee Lee, Min Chung, Yeon Suk Kim, Yeon Ho Park
{"title":"Surgical outcome and prognostic factors in patients with gallbladder carcinoma.","authors":"Eun Kyung Hong, Kun Kuk Kim, Jung Nam Lee, Woon Kee Lee, Min Chung, Yeon Suk Kim, Yeon Ho Park","doi":"10.14701/kjhbps.2014.18.4.129","DOIUrl":"https://doi.org/10.14701/kjhbps.2014.18.4.129","url":null,"abstract":"<p><strong>Backgrounds/aims: </strong>Gallbladder carcinoma is usually associated with an unfavorable prognosis, and the clinical outcome has not improved much. This study was conducted to evaluate outcomes with gallbladder carcinoma according to the type of surgery performed, and the prognostic factors for survival.</p><p><strong>Methods: </strong>One hundred and six patients with gallbladder carcinoma, who underwent surgery for the purpose of curative resection between January 1999 and June 2012 were reviewed retrospectively.</p><p><strong>Results: </strong>Out of 106 patients, curative resection was achieved in 75 (70.8%). The cumulative 1-, 2- and 5-year survival rates of the gallbladder carcinoma patients were 93.4%, 80.9% and 63.0%, respectively. Radical resections, including extended cholecystectomy, were more beneficial for long term survival of patients. The 5-year survival rate in patients who underwent curative resection (56.9%) was significantly higher than in those who underwent palliative resection (0%, p=0.000). Multivariate analysis revealed that curative resection, preoperative CA19-9, T-stage, N-stage and differentiation of histology were independently significant prognostic factors.</p><p><strong>Conclusions: </strong>Curative resection and early detection of patients with gallbladder carcinoma were the most important factors for long term survival. Radical resection improves survival for patients with localized gallbladder carcinoma and can help to access exact prognosis and treatments.</p>","PeriodicalId":91136,"journal":{"name":"Korean journal of hepato-biliary-pancreatic surgery","volume":"18 4","pages":"129-37"},"PeriodicalIF":0.0,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.14701/kjhbps.2014.18.4.129","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34272090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surveillance method and imaging characteristics of recurrent biliary cancer after surgical resection.","authors":"Yong Moon Shin","doi":"10.14701/kjhbps.2014.18.3.73","DOIUrl":"https://doi.org/10.14701/kjhbps.2014.18.3.73","url":null,"abstract":"<p><p>This is a review of the diagnostic imaging techniques and findings of recurrent biliary cancer after surgical resection of the extrahepatic bile duct and gallbladder. Radiological examination plays an important role in diagnosing postoperative recurrence of biliary cancers. Early detection and diagnosis of recurrent cancer is critical in obtaining proper treatment and improves the prognosis. In the surveillance of recurrent biliary cancer, several diagnostic imaging modalities are currently used. Usually CT is the most common method for surveillance of postoperative patients, but MRI and PET/CT scans are also widely used. Recurrent biliary cancer can manifest as local recurrence, liver metastasis, lymph node metastasis, and peritoneal metastasis. Imaging findings of a locally recurrent tumor or metastatic lymph node enlargement overlaps with benign postoperative changes, thus radiologists commonly overlook subtle CT findings or misinterpret them as benign postoperative changes. There are several reports that FDG-PET scan is more effective in the diagnosis of recurrent biliary tract cancer than CT. Multidisciplinary diagnostic approaches using CT, MRI, and FDG-PET as well as clinical information seem to be essential for the precise diagnosis of recurrent tumors. </p>","PeriodicalId":91136,"journal":{"name":"Korean journal of hepato-biliary-pancreatic surgery","volume":"18 3","pages":"73-6"},"PeriodicalIF":0.0,"publicationDate":"2014-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.14701/kjhbps.2014.18.3.73","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33887498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}