Journal of aging science最新文献_第7页

What Causes Age-Related Emotion Recognition Decline? 什么原因导致与年龄相关的情绪识别能力下降?

Journal of aging science Pub Date : 2020-01-01 DOI: 10.35248/2329-8847.20.S3.004

T. Ruffman

引用次数: 1

Subjective Cognitive Decline: Mental Health, Loneliness, Pain and Quality Of Life: Poblational Study 主观认知衰退:心理健康、孤独、疼痛和生活质量:人口研究

Journal of aging science Pub Date : 2020-01-01 DOI: 10.35248/2329-8847.20.8.456

Pedro Montejo Carrasco, D. Crespo, Eduardo Pedrero-Prez, Mercedes Montenegro-Pea

{"title":"Subjective Cognitive Decline: Mental Health, Loneliness, Pain and Quality Of Life: Poblational Study","authors":"Pedro Montejo Carrasco, D. Crespo, Eduardo Pedrero-Prez, Mercedes Montenegro-Pea","doi":"10.35248/2329-8847.20.8.456","DOIUrl":"https://doi.org/10.35248/2329-8847.20.8.456","url":null,"abstract":"Background: Subjective cognitive decline is considered to be a risk for Alzheimer’s disease. However, it can also be associated with non-cognitive variables. Objectives: This study analyzes the association between subjective cognitive decline (SCD) and variables related to memory, mental health, morbidity, pain, quality of life, loneliness, lifestyle, and social aspects; analyzes predictors of SCD. Methods: Cross-sectional epidemiological study of a sample of individuals randomly selected from a city census. Telephone interviews were conducted with 1775 individuals aged over 55 years. We administered a 7-item questionnaire on SCD and asked about health, lifestyle, and social variables; we also administered a measure of general mental health, the Goldberg Health Questionnaire, and the health-related quality of life scale COOP/ WONCA. Results: SCD showed statistically significant associations with orientation in time (r=0.16), mental health variables (r=0.41), quality of life (r=0.36), loneliness (Eta2=0.04), disability (R2=0.05), pain (R2=0.12), hearing difficulties (R2=0.03), vision problems (R2=0.05), and chronic disease (R2=0.04). The variables orientation in time, mental health, depression, sleep quality, multimorbidity, and hearing difficulties were identified as predictors of SCD (p<0.001; R2=0.30). Conclusion: The heterogeneity of the variables associated with SCD should be taken into account to differentiate individuals at increased risk of developing Alzheimer’s disease from those in whom the condition may be explained by other factors.","PeriodicalId":90884,"journal":{"name":"Journal of aging science","volume":"8 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70004120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Oral Administration of Poly-pharmacy in Institutionalized Elderly Patients with Dysphagia 住院老年吞咽困难患者口服多种药物的应用

Journal of aging science Pub Date : 2019-01-01 DOI: 10.35248/2329-8847.19.07.200

Juneo Cesar F, BAA¡rbara Maori dos santos Oliveira

引用次数: 1

Sedentary Time and Disability in Older Adults: A Systematic Review and Meta-Analysis 久坐时间与老年人残疾:系统回顾和荟萃分析

Journal of aging science Pub Date : 2019-01-01 DOI: 10.35248/2329-884.19.07.206

Luria M. L. Scher, F. Guarda, M. Barros, Zhiguo Chen, S. Anton

引用次数: 9

Blood Type Diets (BTD) and Aging: An Overview 血型饮食(BTD)与衰老:综述

Journal of aging science Pub Date : 2019-01-01 DOI: 10.35248/2329-8847.19.07.203

M. Menapace

{"title":"Blood Type Diets (BTD) and Aging: An Overview","authors":"M. Menapace","doi":"10.35248/2329-8847.19.07.203","DOIUrl":"https://doi.org/10.35248/2329-8847.19.07.203","url":null,"abstract":"It has recently been proposed that glycans, being the third alphabet of life, interact intricately with endogenous biomolecules to modulate tolerance, immune and inflammatory responses. Specifically, food glycans could impact health and be a source of inflammation and age-related diseases. These special carbohydrates are present as glycoconjugates (glycoproteins or glycolipids) in and on the surface of all the cells (glycocalyx) of all organisms or are found in free form in biological fluids. Recent advances in glycobiology and glycochemistry have shown how glycans bind with naturally present human proteins (lectins), through protein-carbohydrate interactions (or PCI), but also how oligosaccharides can interact with other glycans, present throughout the human body (through carbohydrate-carbohydrate interactions, or CCI). Oligosaccharides present in food sources, which go beyond the definition of normal fibers, once ingested are then either absorbed in the bloodstream, where they are recognized by the immune system, or interact with the surface of GI epithelial cells, thus generating appropriate biochemical cascades that induce a tolerance or immune/inflammatory response. Because the ABO epitopes have been encountered on all human cells, not just erythrocytes and based on the different biotypology (A, AB, B, and O) impose morphic changes in the distribution of the glycans on the glycocalyx (lipid rafts and clustered saccharide patches), their CCI with food and microbe glycans will be different, thus, eliciting contrasting responses. This can explain the epidemiological data for blood type diets (BTD). Through continuous consumption of the wrong types of glycans, processes of chronic inflammation could be initiated and progress to accelerated aging. Four basic modes of action have been identified showing how glycans can trigger inflamm-aging. Since glycobiology is a young science, further studies with newer technologies are warranted for advancement in this field.","PeriodicalId":90884,"journal":{"name":"Journal of aging science","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70001727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Older Adults and Sexuality in Israel: Knowledge, Attitudes, Sexual Activity and Quality of Life 以色列的老年人和性:知识、态度、性活动和生活质量

Journal of aging science Pub Date : 2019-01-01 DOI: 10.35248/2329-8847.19.07.209

Ahuva Even-Zohar, Shoshi Werner

{"title":"Older Adults and Sexuality in Israel: Knowledge, Attitudes, Sexual Activity and Quality of Life","authors":"Ahuva Even-Zohar, Shoshi Werner","doi":"10.35248/2329-8847.19.07.209","DOIUrl":"https://doi.org/10.35248/2329-8847.19.07.209","url":null,"abstract":"Background: Sexual interest and activity continue to play a role in people's life as they age. However, research on this subject is limited. Purpose: To examine knowledge about sexuality, attitudes towards sexuality and sexual activity, and the relationship of sexual activity to quality of life among older adults in Israel. Method: Data included 203 Israeli Jews, with an average age of 69.59. The participants completed questionnaires, through an Internet panel, about sexuality knowledge and attitudes, sexual activity, quality of life and a sociodemographic questionnaire. Results: The results revealed that older adults continue to engage in sexual activities in later life. Knowledge and permissive attitudes are related to more sexual activity. Frequency of sexual activity was found as a predictor variable of quality of life, indicating a mediating effect on the relationship between attitudes towards older adults’ sexuality and quality of life. Men and older adults who have a spouse have a higher frequency of sexual activity than women and older adults who do not have a spouse. A correlation was found between the variables: health status, economic situation, education, and knowledge, attitudes, and sexual activity. Conclusion: Similar to other societies, Israeli older adults are still interested in sex, and sexual activity contributes to their quality of life. The practical recommendations are aimed primarily at professionals working with the older adult population. The older adults should be encouraged to seek help in the event that problems arise. Educational programs should be designed for the older adults themselves and for professionals as well. Education should emphasize the benefits of older adults' sexuality; provide knowledge of current sexual behavior patterns, and the biological and psychosocial aspects of sexuality.","PeriodicalId":90884,"journal":{"name":"Journal of aging science","volume":"7 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70002073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 19

Is Successful Aging Declining with Age? The Age Profile of Objective, Subjective, and Preference-Based Measures of Successful Aging in Europe 成功的老龄化会随着年龄的增长而下降吗?欧洲成功老龄化的客观、主观和偏好指标的年龄概况

Journal of aging science Pub Date : 2019-01-01 DOI: 10.35248/2329-8847.19.07.215

Koen Decancq, Veerle Van Loon

引用次数: 0

The Association of Coordination with Physical Activity Levels of Older Adults 老年人身体活动水平与协调性的关系

Journal of aging science Pub Date : 2019-01-01 DOI: 10.35248/2329-8847.19.07.212

E. James, M. Karabulut, Phillip Conatser, Suzanne G. Leveille, S. Snih, K. Markides, J. Bean

引用次数: 5

Information Delivery Methods and their Association with Older Adults Memory and Comprehension 信息传递方式及其与老年人记忆和理解的关系

Journal of aging science Pub Date : 2019-01-01 DOI: 10.35248/2329-8847.19.07.207

Y. Imamura, Yuki Murakami, Yoshihide Kimura, O. Maeda, M. Tsujii, Keiji Konishi, Tomoko Nakano, Yoriko Nagai, S. Mitani

{"title":"Information Delivery Methods and their Association with Older Adults Memory and Comprehension","authors":"Y. Imamura, Yuki Murakami, Yoshihide Kimura, O. Maeda, M. Tsujii, Keiji Konishi, Tomoko Nakano, Yoriko Nagai, S. Mitani","doi":"10.35248/2329-8847.19.07.207","DOIUrl":"https://doi.org/10.35248/2329-8847.19.07.207","url":null,"abstract":"The global population is aging. As people age, they typically experience gradual changes in hearing, vision, coordination, balance, working memory, and cognitive function. Products, communication materials, and information provision are often accommodated for older adults. In this study, we examined various information delivery methods and their association with older adults’ working memory and cognitive function (N=18; 10 women). Participants completed tests or followed instructions that consisted of either only figures, only words, or a combination of both figures and words. First, concerning working memory, six well-known information symbols were shown to participants in one of three patterns. Each pattern was displayed on a screen for 20 sec, and working memory was measured as the number of correct items participants recalled. Cognitive function was assessed by participants’ ability to construct three different objects (giraffe, flower, and tulip) using blocks. Participants were presented with various forms of instruction concerning how to build the objects-pictures only, words only, or both pictures and words. Results revealed that the total number of items recalled were 4.3 ± 1.4, 3.1 ± 1.1, and 3.9 ± 0.8 for figures only, words only, and both figures and words, respectively (χ2=10.13, p=0.006). Higher working memory scores were associated with “figure only” and “figures and words” as compared with the “words only” method. Regarding comprehension, higher scores were associated with “figures and words” instructions as compared to the “figures only” and “words only” instructions. In conclusion, information provision for older adults should be simple and easy, visuals should be employed, and supplemental information should be explained in words to avoid any misunderstandings.","PeriodicalId":90884,"journal":{"name":"Journal of aging science","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70002095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

POOL-SEQ Study of Bulgarian Centenarians Highlights the Relevance for Human Longevity of Gene Expression Pathways 保加利亚百岁老人的POOL-SEQ研究强调了基因表达途径与人类寿命的相关性

Journal of aging science Pub Date : 2019-01-01 DOI: 10.35248/2329-8847.19.07.208

D. Serbezov, L. Balabanski, S. Karachanak-Yankova, R. Vazharova, D. Nesheva, Zora Hammoudeh, R. Staneva, Marta Mihaylova, V. Damyanova, O. Antonova, D. Nikolova, S. Hadjidekova, D. Toncheva

{"title":"POOL-SEQ Study of Bulgarian Centenarians Highlights the Relevance for Human Longevity of Gene Expression Pathways","authors":"D. Serbezov, L. Balabanski, S. Karachanak-Yankova, R. Vazharova, D. Nesheva, Zora Hammoudeh, R. Staneva, Marta Mihaylova, V. Damyanova, O. Antonova, D. Nikolova, S. Hadjidekova, D. Toncheva","doi":"10.35248/2329-8847.19.07.208","DOIUrl":"https://doi.org/10.35248/2329-8847.19.07.208","url":null,"abstract":"In human longevity studies a large number of genetic variants with small effects have been identified, but these are not easily replicable in different populations. We have performed whole-exome sequencing of two DNA pools from: 32 Bulgarian centenarians and 61 young healthy controls, respectively. A total of 59935 filtered variants were discovered, 216 of which were included in Longevity Map database which lists 2843 longevity associated variants. Using Fisher’s exact test, 22 of these variants showed significantly higher allele frequency in the centenarian compared to the control pool and are thus positively associated with longevity. Other 24 variants had significantly higher frequency in the controls and could be considered as negatively associated with longevity. The risk C allele in rs429358 of the APOE gene was only detected in the control pool and with lower frequency compared to other populations. REACTOME analyses showed that over-represented pathways with positive longevity variants belong to expression/transcription network with leading role of TP53, interplaying with other genes (ATR, FANCD2, BAX, BRIP1), whereas those with negative longevity variants belong to the signal transduction network. Our results confirm the importance of studying centenarians in different populations to discover those combinations of variants that associate with longer health span.","PeriodicalId":90884,"journal":{"name":"Journal of aging science","volume":"7 1","pages":"1-14"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70002215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2