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Complications following surgical management of a fish bone-related abscess in the liver. 肝脏鱼骨相关脓肿手术处理后的并发症。
IF 0.4
BMJ Case Reports Pub Date : 2026-08-25 DOI: 10.1136/bcr-2025-267911
Madhav Kukreja, Adil Jehangir Khan, Ayodele Odusote, Girish Girish
{"title":"Complications following surgical management of a fish bone-related abscess in the liver.","authors":"Madhav Kukreja, Adil Jehangir Khan, Ayodele Odusote, Girish Girish","doi":"10.1136/bcr-2025-267911","DOIUrl":"10.1136/bcr-2025-267911","url":null,"abstract":"<p><p>We present the case of a woman in her early 70s who developed a liver abscess secondary to fish bone ingestion. This report highlights the diagnostic challenges, management considerations and postoperative complications associated with this rare presentation, emphasising its potential morbidity.</p>","PeriodicalId":9080,"journal":{"name":"BMJ Case Reports","volume":"19 8","pages":""},"PeriodicalIF":0.4,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13535659/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148817397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pott's puffy tumour based on Aggregatibacter aphrophilus in an adult patient with bilateral cheilognathopalatoschisis. 成人双侧唇腭裂患者的Pott肿性肿瘤。
IF 0.4
BMJ Case Reports Pub Date : 2026-08-25 DOI: 10.1136/bcr-2025-265510
Sadaf Soloukey, Daphna Hoefnagel, Mick de Vogel, Andries Paul Nagtegaal, Anne Kleijn
{"title":"Pott's puffy tumour based on <i>Aggregatibacter aphrophilus</i> in an adult patient with bilateral cheilognathopalatoschisis.","authors":"Sadaf Soloukey, Daphna Hoefnagel, Mick de Vogel, Andries Paul Nagtegaal, Anne Kleijn","doi":"10.1136/bcr-2025-265510","DOIUrl":"10.1136/bcr-2025-265510","url":null,"abstract":"<p><p>Pott's puffy tumour (PPT) is a rare condition defined by subperiosteal abscess formation following osteomyelitis of the frontal bone. Complications can be severe and involve intracranial progression.Here, we present a rare case of a PPT due to an <i>Aggregatibacter aphrophilus</i> infection of odontogenic origin in a young adult patient with a history of bilateral cheilognathopalatoschisis. Due to the unusual location of the abscess, the diagnosis was initially missed, leading to a delay of more than 1 month until adequate treatment. Odontogenic treatment was initiated as source control, external drainage of the abscess was performed and intravenous and later oral antibiotics were administered, which, despite relatively poor treatment adherence, ultimately led to adequate control of the infection without the need for further surgical intervention. The current case is the first report to highlight cleft palate-and consequent poorer oral health-as a potential predisposing condition for PPT.</p>","PeriodicalId":9080,"journal":{"name":"BMJ Case Reports","volume":"19 8","pages":""},"PeriodicalIF":0.4,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148817410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Negative-pressure pulmonary oedema following upper airway obstruction after tracheal extubation in an adolescent undergoing general anaesthesia for dental extractions. 青少年拔牙全麻后气管拔管后上呼吸道阻塞的负压肺水肿。
IF 0.4
BMJ Case Reports Pub Date : 2026-08-25 DOI: 10.1136/bcr-2025-269379
Carla Retroz-Marques, Diogo Ferreira, Inês Retroz Marques, Acilio Marques
{"title":"Negative-pressure pulmonary oedema following upper airway obstruction after tracheal extubation in an adolescent undergoing general anaesthesia for dental extractions.","authors":"Carla Retroz-Marques, Diogo Ferreira, Inês Retroz Marques, Acilio Marques","doi":"10.1136/bcr-2025-269379","DOIUrl":"https://doi.org/10.1136/bcr-2025-269379","url":null,"abstract":"<p><p>A healthy athletic adolescent male with a remote history of asymptomatic childhood asthma underwent outpatient multiple molar extractions under general anaesthesia with tracheal intubation. Shortly after gentle tracheal extubation, he developed acute upper airway obstruction with oxygen desaturation and increased work of breathing, despite careful oropharyngeal aspiration and confirmed reversal of neuromuscular blockade. Initial airway manoeuvres and face-mask ventilation with 100% oxygen against high airway resistance provided only transient improvement, requiring tracheal re-intubation and positive-pressure ventilation. Following subsequent uneventful tracheal extubation, he developed recurrent respiratory distress in the post-anaesthesia care unit, characterised by biphasic stridor, bilateral crackles and scant frothy secretions. As cardiogenic causes were excluded by transthoracic echocardiography, the clinical presentation was consistent with negative-pressure pulmonary oedema. Supportive management, including supplemental oxygen, careful fluid balance and diuretic therapy under close monitoring, resulted in progressive clinical improvement. The patient made a full recovery and was discharged 24 hours postoperatively.</p>","PeriodicalId":9080,"journal":{"name":"BMJ Case Reports","volume":"19 8","pages":""},"PeriodicalIF":0.4,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148817362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Straatsma syndrome: the diagnostic value of dilated funduscopy in anisometropic amblyopia. 斜视综合征：扩大眼底镜对屈光参差性弱视的诊断价值。
IF 0.4
BMJ Case Reports Pub Date : 2026-08-25 DOI: 10.1136/bcr-2026-273925
Daniah Albaloul, Noor Alali, Aseel AlKandari, Alaa Al-Ali
{"title":"Straatsma syndrome: the diagnostic value of dilated funduscopy in anisometropic amblyopia.","authors":"Daniah Albaloul, Noor Alali, Aseel AlKandari, Alaa Al-Ali","doi":"10.1136/bcr-2026-273925","DOIUrl":"https://doi.org/10.1136/bcr-2026-273925","url":null,"abstract":"<p><p>Straatsma syndrome is a rare condition defined by the triad of unilateral high axial myopia, amblyopia and myelinated retinal nerve fibre layer (MRNFL). Visual prognosis is often guarded when myelination is extensive, the macula is involved, or anisometropia is high. We present a case of classic Straatsma syndrome in a boy in his middle childhood from the Arabian Gulf region. In the right eye, he had extensive type 2 MRNFL involving the superior macula, high axial myopia and amblyopia. Given his age and extensive MRNFL, retinoblastoma was excluded. We describe his longitudinal clinical course and multimodal imaging findings. Despite recommended occlusion therapy and refractive correction, the family declined treatment, and best-corrected visual acuity remained at counting fingers at 1-year follow-up. The case highlights the value of dilated fundus examination in children with anisometropic amblyopia or unilateral high myopia to facilitate timely diagnosis and appropriate prognostic counselling.</p>","PeriodicalId":9080,"journal":{"name":"BMJ Case Reports","volume":"19 8","pages":""},"PeriodicalIF":0.4,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148817456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glioma-associated oncogene homolog 1-altered mesenchymal tumour of the upper oesophageal sphincter. 胶质瘤相关癌基因同源1改变的食管上括约肌间充质瘤。
IF 0.4
BMJ Case Reports Pub Date : 2026-08-25 DOI: 10.1136/bcr-2026-272971
Sage Hebert, Mallory Peters, Areli Cuevas-Ocampo, Karuna Dewan
{"title":"Glioma-associated oncogene homolog 1-altered mesenchymal tumour of the upper oesophageal sphincter.","authors":"Sage Hebert, Mallory Peters, Areli Cuevas-Ocampo, Karuna Dewan","doi":"10.1136/bcr-2026-272971","DOIUrl":"10.1136/bcr-2026-272971","url":null,"abstract":"<p><p>Glioma-associated oncogene homologue 1-altered mesenchymal tumours (GLI1-AMT) are rare, recently characterised soft tissue neoplasms driven by GLI1 fusions or amplifications. They predominantly arise in the head and neck, though their full clinicopathological presentation remains variable.A female in her 30s with a year-long history of progressive dysphagia was found to have a GLI1-AMT of the upper oesophageal sphincter, the first known case at this site. She underwent laser excision of the mass with adjuvant radiotherapy with no disease recurrence to date.Literature review identified 42 additional cases in the head and neck, most commonly affecting the tongue. Genetic alterations include GLI1 amplifications, frequently co-amplified with CDK4 and MDM2, and fusions, typically with ACTB, PTCH1 or MALAT1. Immunohistochemical staining patterns are inconsistent, though CD56, S100 and MDM2 are frequently positive.Classification of GLI1-AMT has evolved over recent years, and research is needed to refine diagnostic criteria and elucidate the behaviour of this spectrum of neoplasms.</p>","PeriodicalId":9080,"journal":{"name":"BMJ Case Reports","volume":"19 8","pages":""},"PeriodicalIF":0.4,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13535660/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148817372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Distal femur replacement after catastrophic failure of a total knee arthroplasty. 全膝关节置换术失败后的股骨远端置换术。
IF 0.4
BMJ Case Reports Pub Date : 2026-08-25 DOI: 10.1136/bcr-2026-272954
Alex Rice, Parvati Dadwal, Andrew Witherow, Grant Menegon, Chris Wall
{"title":"Distal femur replacement after catastrophic failure of a total knee arthroplasty.","authors":"Alex Rice, Parvati Dadwal, Andrew Witherow, Grant Menegon, Chris Wall","doi":"10.1136/bcr-2026-272954","DOIUrl":"10.1136/bcr-2026-272954","url":null,"abstract":"<p><p>Catastrophic implant failure is a rare complication after total knee arthroplasty (TKA) that can lead to metallosis and pseudotumour formation requiring complex revision surgery. This case report describes a man in his 60s who presented with progressive knee pain, a squeaking implant and ligamentous instability 20 years post-primary TKA. Imaging demonstrated polyethylene failure, tibial baseplate breakage, extensive osteolysis and metallosis. The patient underwent a revision procedure with a distal femur replacement (DFR). Postoperatively he had no complications, re-admissions or revision surgery. At 4 years post DFR, he remained asymptomatic with excellent functional outcomes (Oxford Knee Score 45 out of 48; Forgotten Joint Score 98 out of 100). This case highlights DFR as a viable salvage option in appropriately selected patients where conventional revision TKA is not possible.</p>","PeriodicalId":9080,"journal":{"name":"BMJ Case Reports","volume":"19 8","pages":""},"PeriodicalIF":0.4,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148817386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Re-evaluating absolute neutrophil count thresholds: Duffy-null-associated neutrophil count in cancer treatment. 重新评估绝对中性粒细胞计数阈值：duffy -null相关中性粒细胞计数在癌症治疗中的应用。
IF 0.4
BMJ Case Reports Pub Date : 2026-08-25 DOI: 10.1136/bcr-2026-273931
Michael Xu, Samuel R Wilson, Stephan Moll, Brian C Miller, Catherine C Fahey
{"title":"Re-evaluating absolute neutrophil count thresholds: Duffy-null-associated neutrophil count in cancer treatment.","authors":"Michael Xu, Samuel R Wilson, Stephan Moll, Brian C Miller, Catherine C Fahey","doi":"10.1136/bcr-2026-273931","DOIUrl":"https://doi.org/10.1136/bcr-2026-273931","url":null,"abstract":"<p><p>The Duffy-null phenotype is associated with fewer circulating blood neutrophils. This phenomenon, termed Duffy-null-associated neutrophil count (DANC), is common among individuals of African and Middle Eastern ancestry. Despite growing evidence that DANC does not increase the risk of infectious complications, oncology treatment protocols often rely on standardised absolute neutrophil count (ANC) thresholds to guide chemotherapy dosing and clinical trial candidacy. This reliance risks inappropriate dose reductions or treatment delays in patients with DANC. We present a patient with DANC and high-volume metastatic hormone-sensitive prostate cancer in whom lower neutrophil counts, found to be due to DANC, delayed initiation of chemotherapy and led to the use of granulocyte-colony stimulating factor (G-CSF). This case highlights the dilemma that DANC may lead clinicians to delay chemotherapy and/or use G-CSF when neither may be needed. Future clinical studies are needed to develop DANC-specific thresholds for standard dose chemotherapy and G-CSF support.</p>","PeriodicalId":9080,"journal":{"name":"BMJ Case Reports","volume":"19 8","pages":""},"PeriodicalIF":0.4,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148817401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Shoshin beriberi with severe lactic acidosis and haemodynamic collapse due to long-term diuretic therapy. 由于长期利尿剂治疗导致的严重乳酸酸中毒和血流动力学衰竭。
IF 0.4
BMJ Case Reports Pub Date : 2026-08-25 DOI: 10.1136/bcr-2026-272300
Anees C K, Jeevan Jacob, Arjun C, Jitha Devan
{"title":"Shoshin beriberi with severe lactic acidosis and haemodynamic collapse due to long-term diuretic therapy.","authors":"Anees C K, Jeevan Jacob, Arjun C, Jitha Devan","doi":"10.1136/bcr-2026-272300","DOIUrl":"https://doi.org/10.1136/bcr-2026-272300","url":null,"abstract":"<p><p>A patient on long-term diuretic treatment for pulmonary arterial hypertension presented with acute haemodynamic instability and profound high anion gap metabolic acidosis. Investigations showed severe lactic acidosis with no evidence of sepsis, hypoxia, diabetic ketoacidosis, acute pulmonary embolism or mesenteric ischaemia. Despite fluid resuscitation, vasopressor support and ventilatory support, the metabolic derangement persisted. Since she was on prolonged diuretic use and no other cause was identified, thiamine deficiency was suspected. Empirical intravenous thiamine administration led to rapid and sustained improvement in acid-base status and haemodynamics, allowing tapering of vasopressors. This case highlights thiamine deficiency as an under-recognised but readily reversible cause of severe lactic acidosis and cardiovascular collapse, particularly in patients receiving chronic diuretic therapy.</p>","PeriodicalId":9080,"journal":{"name":"BMJ Case Reports","volume":"19 8","pages":""},"PeriodicalIF":0.4,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148817466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recurrent synovial chondromatosis of the shoulder treated with osteochondral allograft transplantation. 异体骨软骨移植治疗复发性肩关节滑膜软骨瘤病。
IF 0.4
BMJ Case Reports Pub Date : 2026-08-25 DOI: 10.1136/bcr-2025-269370
Nain Kamal Aulakh, Cansu Ozdemir, Siddhartha Murhekar, Bijayendra Singh
{"title":"Recurrent synovial chondromatosis of the shoulder treated with osteochondral allograft transplantation.","authors":"Nain Kamal Aulakh, Cansu Ozdemir, Siddhartha Murhekar, Bijayendra Singh","doi":"10.1136/bcr-2025-269370","DOIUrl":"10.1136/bcr-2025-269370","url":null,"abstract":"<p><p>This case concerns synovial chondromatosis, which is an uncommon and benign joint disorder marked by intra-articular cartilaginous nodules. It predominantly affects males, with the knee most involved while shoulder involvement is uncommon. Arthroscopy remains the primary treatment for synovial chondromatosis; however, osteochondral allograft transplantation (OAT) is emerging as a valuable option, particularly in recurrent cases. Because shoulder synovial chondromatosis is rare, evidence regarding long-term outcomes remains limited, making optimal management uncertain.We report a case of a woman in her early 20s with recurrent right shoulder synovial chondromatosis and progressive humeral head erosion following two arthroscopic procedures. This case highlights the role of OAT in structurally compromised glenohumeral joints as arthroscopy alone was insufficient. Follow-up assessments at 1, 3, 12 months and 2 years demonstrated progressive clinical improvement, with the patient achieving near full range of motion by 3 months and full function by 12 months. Imaging at each stage confirmed satisfactory graft integration and healing.</p>","PeriodicalId":9080,"journal":{"name":"BMJ Case Reports","volume":"19 8","pages":""},"PeriodicalIF":0.4,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148817387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An uncommon side effect of statins: perioral neuropathic symptoms. 他汀类药物不常见的副作用：口周神经性症状。
IF 0.4
BMJ Case Reports Pub Date : 2026-08-24 DOI: 10.1136/bcr-2026-274770
Kerolus H Anis, John Malaty
{"title":"An uncommon side effect of statins: perioral neuropathic symptoms.","authors":"Kerolus H Anis, John Malaty","doi":"10.1136/bcr-2026-274770","DOIUrl":"https://doi.org/10.1136/bcr-2026-274770","url":null,"abstract":"<p><p>A male patient in his 60s, with a history of hypertension and hyperlipidaemia, presented with a sensation of dryness, itchiness, numbness and tingling around his mouth that started after taking atorvastatin, suggesting a small-fibre neuropathy related to statin use. He was prescribed statins based on increased 10-year atherosclerotic cardiovascular disease risk (9.7%) and hyperlipidaemia. This observed side effect subsided when the medication was stopped. Evaluation was conducted to rule out other underlying aetiologies of his symptoms, and it was confirmed that the statins were the cause of the symptoms when two additional repeat statin trials, with both atorvastatin and rosuvastatin, caused similar side effects that promptly resolved within a few days of stopping the medications.</p>","PeriodicalId":9080,"journal":{"name":"BMJ Case Reports","volume":"19 8","pages":""},"PeriodicalIF":0.4,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148811790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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