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Placenta accreta spectrum as a complication of transabdominal cerclage. 胎盘增生谱作为经腹环扎术的并发症。
IF 0.6
BMJ Case Reports Pub Date : 2025-07-07 DOI: 10.1136/bcr-2024-264194
Heleen Scherrenberg, Anne-Sophie Van Rompuy, Michael Aertsen, Johannes van der Merwe
{"title":"Placenta accreta spectrum as a complication of transabdominal cerclage.","authors":"Heleen Scherrenberg, Anne-Sophie Van Rompuy, Michael Aertsen, Johannes van der Merwe","doi":"10.1136/bcr-2024-264194","DOIUrl":"https://doi.org/10.1136/bcr-2024-264194","url":null,"abstract":"<p><p>Cervical cerclage, particularly transabdominal cerclage (TAC), is a last resort surgical procedure to manage cervical incompetence. Despite its high success rate, TAC carries inherent risks and can result in complications. Placenta accreta spectrum (PAS) disorder, a rare iatrogenic condition linked to previous uterine surgeries, especially caesarean sections, poses a significant risk of severe obstetric haemorrhage during delivery, often leading to maternal and neonatal morbidity.This case presents a woman in her 30s with a history of cervical insufficiency who underwent an abdominal cerclage. An uneventful pregnancy ensued, leading to a planned caesarean delivery. However, her subsequent pregnancy was complicated by cerclage erosion, uterine scar dehiscence and ultimately PAS disorder. These complications were confirmed through transvaginal ultrasound and MRI assessments prenatally and on histopathology after birth. A caesarean hysterectomy was performed at 32 weeks due to threatened preterm labour. Both mother and her infant experienced an uncomplicated postpartum and neonatal recovery.</p>","PeriodicalId":9080,"journal":{"name":"BMJ Case Reports","volume":"18 7","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ectopic ureter in two distinct Müllerian anomalies. 异位输尿管在两个不同的<s:1>勒氏管异常。
IF 0.6
BMJ Case Reports Pub Date : 2025-07-07 DOI: 10.1136/bcr-2025-266450
Avantika Gupta, Arun Kumar Dora, Satish Choudhury, Ketan Mehra
{"title":"Ectopic ureter in two distinct Müllerian anomalies.","authors":"Avantika Gupta, Arun Kumar Dora, Satish Choudhury, Ketan Mehra","doi":"10.1136/bcr-2025-266450","DOIUrl":"https://doi.org/10.1136/bcr-2025-266450","url":null,"abstract":"","PeriodicalId":9080,"journal":{"name":"BMJ Case Reports","volume":"18 7","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary large bowel lymphoma with ileo-colic intussusception. 原发性大肠淋巴瘤伴回肠-结肠肠套叠。
IF 0.6
BMJ Case Reports Pub Date : 2025-07-07 DOI: 10.1136/bcr-2025-265841
Divij Agarwal, Somil Anshal, Amarinder Singh Malhi
{"title":"Primary large bowel lymphoma with ileo-colic intussusception.","authors":"Divij Agarwal, Somil Anshal, Amarinder Singh Malhi","doi":"10.1136/bcr-2025-265841","DOIUrl":"https://doi.org/10.1136/bcr-2025-265841","url":null,"abstract":"","PeriodicalId":9080,"journal":{"name":"BMJ Case Reports","volume":"18 7","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neuroschistosomiasis: rare CNS infection in a preschool-aged child. 神经血吸虫病：罕见的学龄前儿童中枢神经系统感染。
IF 0.6
BMJ Case Reports Pub Date : 2025-07-07 DOI: 10.1136/bcr-2025-266330
Diyar Hasan Nernji, Narayanan Panicker, Hilal Alhashami, Khalid Mohammed
{"title":"Neuroschistosomiasis: rare CNS infection in a preschool-aged child.","authors":"Diyar Hasan Nernji, Narayanan Panicker, Hilal Alhashami, Khalid Mohammed","doi":"10.1136/bcr-2025-266330","DOIUrl":"https://doi.org/10.1136/bcr-2025-266330","url":null,"abstract":"<p><p>Neuroschistosomiasis is a rare but severe manifestation of <i>Schistosoma</i> infection with a challenging diagnosis. We present a paediatric case of neuroschistosomiasis, presenting with persistent vomiting, headache and irritability for seven days. Fundoscopic examination revealed bilateral papilloedema. Brain MRI findings revealed mildly distended sheaths and tortuous optic nerve, suggesting intracranial hypertension. CSF manometry revealed high opening pressure. Schistosomiasis antibodies in blood and CSF were strongly positive. The patient demonstrated an excellent therapeutic response to serial CSF drainage, empirical praziquantel, acetazolamide and corticosteroid treatment. The child gradually improved without neurological sequelae. Prompt diagnosis and treatment are crucial for a favourable outcome and minimising the risk of permanent neurological impairment.</p>","PeriodicalId":9080,"journal":{"name":"BMJ Case Reports","volume":"18 7","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hypocalcemia and hypophosphatemia due to osteoblastic metastases from central nervous system embryonal tumour. 中枢神经系统胚胎性肿瘤成骨细胞转移引起的低钙和低磷血症。
IF 0.6
BMJ Case Reports Pub Date : 2025-07-07 DOI: 10.1136/bcr-2025-264881
Rajesh Yadav Borra, Venkata Sai Krishna Reddy Nareddy, Pooja Chavali, Raza Shabuddin Gouri
{"title":"Hypocalcemia and hypophosphatemia due to osteoblastic metastases from central nervous system embryonal tumour.","authors":"Rajesh Yadav Borra, Venkata Sai Krishna Reddy Nareddy, Pooja Chavali, Raza Shabuddin Gouri","doi":"10.1136/bcr-2025-264881","DOIUrl":"https://doi.org/10.1136/bcr-2025-264881","url":null,"abstract":"<p><p>A male in his early 20s presented with severe skeletal pain and diffuse osteosclerosis caused by extensive osteoblastic skeletal metastases from a Central Nervous System (CNS) Embryonal Tumour (WHO Grade 4), leading to hypocalcemia and hypophosphatemia. Biochemical evaluation revealed elevated parathyroid hormone and high vitamin D levels; imaging confirmed widespread osteoblastic metastases. Low urinary fractional excretion of calcium suggested high uptake into the bone. The biochemical profile resembled vitamin D resistance but represents a distinct pathophysiological entity. Pancytopenia due to marrow infiltration precluded chemotherapy and radiotherapy, prompting a focus on supportive and palliative care. Management included oral calcium and phosphorus supplementation alongside symptom control and psychosocial support. This case illustrates the rare metabolic complication of hypocalcemia and hypophosphatemia secondary to osteoblastic metastases in a CNS malignancy. It emphasises recognising such metabolic derangements and adopting a multidisciplinary approach to optimise management and improve patient quality of life.</p>","PeriodicalId":9080,"journal":{"name":"BMJ Case Reports","volume":"18 7","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recurrent respiratory papillomatosis causing critical airway obstruction in the third trimester of pregnancy. 妊娠晚期复发性呼吸道乳头状瘤病引起严重气道阻塞。
IF 0.6
BMJ Case Reports Pub Date : 2025-07-07 DOI: 10.1136/bcr-2024-261786
Thomas Hughes, Andrew Kinshuck, B Batuwitage, Ruth Vlies
{"title":"Recurrent respiratory papillomatosis causing critical airway obstruction in the third trimester of pregnancy.","authors":"Thomas Hughes, Andrew Kinshuck, B Batuwitage, Ruth Vlies","doi":"10.1136/bcr-2024-261786","DOIUrl":"https://doi.org/10.1136/bcr-2024-261786","url":null,"abstract":"<p><p>Recurrent respiratory papillomatosis (RRP) is a rare complication of human papillomavirus infection, resulting in exophytic growths into the respiratory tract.A primigravida patient with RRP presented with increasing stridor at 32 weeks of gestation. The patient required emergency surgery at a tertiary head and neck centre, with a standby obstetric and neonatal team available, and later went on to have a normal term delivery.RRP in pregnancy carries a high risk of airway compromise and requires a multidisciplinary approach to manage the condition. Hospitals should have local guidelines on the location for non-obstetric surgery during pregnancy.</p>","PeriodicalId":9080,"journal":{"name":"BMJ Case Reports","volume":"18 7","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Splenic haemangioma presenting with Kasabach-Merritt syndrome. 脾血管瘤表现为Kasabach-Merritt综合征。
IF 0.6
BMJ Case Reports Pub Date : 2025-07-07 DOI: 10.1136/bcr-2025-265825
Divij Agarwal, Abhilash Gunasekaran, Amarinder Singh Malhi
{"title":"Splenic haemangioma presenting with Kasabach-Merritt syndrome.","authors":"Divij Agarwal, Abhilash Gunasekaran, Amarinder Singh Malhi","doi":"10.1136/bcr-2025-265825","DOIUrl":"https://doi.org/10.1136/bcr-2025-265825","url":null,"abstract":"","PeriodicalId":9080,"journal":{"name":"BMJ Case Reports","volume":"18 7","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From immunotherapy to autoimmunity: reactive arthritis following intravesical BCG. 从免疫治疗到自身免疫：膀胱注射卡介苗后的反应性关节炎。
IF 0.6
BMJ Case Reports Pub Date : 2025-07-07 DOI: 10.1136/bcr-2025-267448
Saad Alqasem, Sophie Wojcik, Jacques Corcos
{"title":"From immunotherapy to autoimmunity: reactive arthritis following intravesical BCG.","authors":"Saad Alqasem, Sophie Wojcik, Jacques Corcos","doi":"10.1136/bcr-2025-267448","DOIUrl":"https://doi.org/10.1136/bcr-2025-267448","url":null,"abstract":"<p><p>Reactive arthritis (ReA) is recognised as a sterile inflammatory arthritis triggered by infections or other antigens, including intravesical BCG used to treat non-muscle-invasive bladder cancer. Although BCG immunotherapy is highly effective, its side effects can extend beyond the genitourinary tract. We present a woman in her 60s with high-grade Ta urothelial cell carcinoma (UCC) and carcinoma in situ (CIS) who developed ReA 1 week following BCG instillation. She experienced fevers, blurred vision, mild conjunctivitis and oligoarthritis predominantly affecting her knees. Infection was ruled out by negative cultures, while elevated inflammatory markers pointed to an autoimmune aetiology. Prompt discontinuation of BCG and corticosteroid therapy led to significant clinical improvement. This case underscores the importance of recognising ReA as a potential post-BCG complication requiring multidisciplinary management. It highlights the need for intervention and follow-up.</p>","PeriodicalId":9080,"journal":{"name":"BMJ Case Reports","volume":"18 7","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Idiopathic pulmonary haemosiderosis in childhood. 儿童特发性肺血黄素病。
IF 0.6
BMJ Case Reports Pub Date : 2025-07-07 DOI: 10.1136/bcr-2025-265327
Hans Vaish
{"title":"Idiopathic pulmonary haemosiderosis in childhood.","authors":"Hans Vaish","doi":"10.1136/bcr-2025-265327","DOIUrl":"10.1136/bcr-2025-265327","url":null,"abstract":"<p><p>This report describes a case involving a boy in his middle childhood with a history of recurrent iron deficiency anaemia, accompanied by respiratory distress, tachypnoea and cyanosis. The respiratory distress improved with pulse doses of methylprednisolone and respiratory support using high-flow oxygen via heated humidified nasal cannula. During each admission, respiratory distress was resolved after administering pulse methylprednisolone. The child was admitted five times with such episodes in the paediatric intensive care unit (PICU). X-rays and high-resolution CT of the chest performed during respiratory distress showed diffuse ground-glass opacities and multiple areas of consolidation. After excluding sepsis, autoimmune diseases and vasculitis, a bronchoscopic alveolar lavage was conducted, revealing haemosiderin-laden macrophages. Having ruled out other causes of diffuse alveolar haemorrhage, this case was identified as idiopathic pulmonary haemosiderosis (IPH). Following discharge from the PICU and resolution of respiratory distress, the child was started on maintenance immunosuppression with prednisolone at 15 mg/day.</p>","PeriodicalId":9080,"journal":{"name":"BMJ Case Reports","volume":"18 7","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12231081/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic quagmires to miraculous resolutions: pulmonary hypertension in pregnancy. 诊断泥潭奇迹般的解决方案：肺动脉高压妊娠。
IF 0.6
BMJ Case Reports Pub Date : 2025-07-05 DOI: 10.1136/bcr-2024-264211
Indrani Mukhopadhyay, Sanjay Singh, Namrat Das, Akanksha Tevatia
{"title":"Diagnostic quagmires to miraculous resolutions: pulmonary hypertension in pregnancy.","authors":"Indrani Mukhopadhyay, Sanjay Singh, Namrat Das, Akanksha Tevatia","doi":"10.1136/bcr-2024-264211","DOIUrl":"10.1136/bcr-2024-264211","url":null,"abstract":"<p><p>The study presents a second gravida in her middle age at 25 weeks and 2-day period of gestation with progressive dyspnoea even at rest (New York Heart Association Class IV), palpitations of 3 months, tachycardia, tachypnoea, pallor, clubbing, elevated jugular venous pressure and SpO2 of 80-90%. ECG revealed sinus tachycardia, right ventricular strain and right bundle-branch block. Echocardiography highlighted increased right pulmonary arterial pressures (pulmonary artery pressure of 60/30/42 mm Hg, pulmonary capillary wedge pressure of 30 mm Hg), a dilated right ventricle and elevated right ventricular systolic pressure. A chest X-ray identified bronchiectasis changes. Despite maintaining oxygen saturation through a high-flow nasal cannula (FiO2, 30%), the patient experienced persistent tachypnoea and required oxygen (FiO2, 70%). The ongoing cardiac and pulmonary evaluation did not reveal any autoimmune, hormonal or infective causes of bronchiectasis or pulmonary hypertension.Given the worsening condition, a caesarean section was performed at 32 weeks gestation in a semirecumbent position under epidural anaesthesia with transversus abdominis plane block and she delivered a live preterm neonate. The postoperative phase was managed with inotropes and high-flow nasal oxygen with gradual weaning off of oxygen over 12 weeks.The patient's complex presentation highlights the importance of management of a high-risk case of pulmonary hypertension while continuing a pregnancy with integrated care by addressing severe cardiovascular and pulmonary issues.</p>","PeriodicalId":9080,"journal":{"name":"BMJ Case Reports","volume":"18 7","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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