D. Chang, Jacquelyn A. Holt, Marisa Sklar, E. Groessl
{"title":"Yoga as a treatment for chronic low back pain: A systematic review of the literature","authors":"D. Chang, Jacquelyn A. Holt, Marisa Sklar, E. Groessl","doi":"10.13188/2334-2846.1000018","DOIUrl":"https://doi.org/10.13188/2334-2846.1000018","url":null,"abstract":"Objectives Chronic low back pain (CLBP) affects millions of people worldwide, and appears to be increasing in prevalence. It is associated not only with pain, but also with increased disability, psychological symptoms, and reduced quality of life. There are various treatment options for CLBP, but no single therapy stands out as being the most effective. In the past 10 years, yoga interventions have been studied as a CLBP treatment approach. The objective of this paper is to review the current literature supporting the efficacy of yoga for CLBP. Methods A literature search through the beginning of 2015 was conducted in Pub Med for randomized control trials addressing treatment of CLBP with yoga. Results In this review we evaluate the use of yoga as a treatment for CLBP. Specifically we evaluate how yoga impacts physical functioning and disability, pain, and associated psychological symptoms. We also evaluate possible mediators of the effect of yoga and the safety of yoga. Discussion With few exceptions, previous studies and the recent randomized control trials (RCTs) indicate that yoga can reduce pain and disability, can be practiced safely, and is well received by participants. Some studies also indicate that yoga may improve psychological symptoms, but these effects are currently not as well established.","PeriodicalId":90612,"journal":{"name":"Journal of orthopedics & rheumatology","volume":"3 1","pages":"1 - 8"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66210181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Douglas G Chang, Jacquelyn A Holt, Marisa Sklar, Erik J Groessl
{"title":"Yoga as a treatment for chronic low back pain: A systematic review of the literature.","authors":"Douglas G Chang, Jacquelyn A Holt, Marisa Sklar, Erik J Groessl","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>Chronic low back pain (CLBP) affects millions of people worldwide, and appears to be increasing in prevalence. It is associated not only with pain, but also with increased disability, psychological symptoms, and reduced quality of life. There are various treatment options for CLBP, but no single therapy stands out as being the most effective. In the past 10 years, yoga interventions have been studied as a CLBP treatment approach. The objective of this paper is to review the current literature supporting the efficacy of yoga for CLBP.</p><p><strong>Methods: </strong>A literature search through the beginning of 2015 was conducted in Pub Med for randomized control trials addressing treatment of CLBP with yoga.</p><p><strong>Results: </strong>In this review we evaluate the use of yoga as a treatment for CLBP. Specifically we evaluate how yoga impacts physical functioning and disability, pain, and associated psychological symptoms. We also evaluate possible mediators of the effect of yoga and the safety of yoga.</p><p><strong>Discussion: </strong>With few exceptions, previous studies and the recent randomized control trials (RCTs) indicate that yoga can reduce pain and disability, can be practiced safely, and is well received by participants. Some studies also indicate that yoga may improve psychological symptoms, but these effects are currently not as well established.</p>","PeriodicalId":90612,"journal":{"name":"Journal of orthopedics & rheumatology","volume":"3 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34419299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samantha H Lee, Michael Padilla, J. E. Lynch, A. Hargens
{"title":"Noninvasive Measurements of Pressure for Detecting Compartment Syndromes.","authors":"Samantha H Lee, Michael Padilla, J. E. Lynch, A. Hargens","doi":"10.13188/2334-2846.1000005","DOIUrl":"https://doi.org/10.13188/2334-2846.1000005","url":null,"abstract":"BACKGROUND\u0000We tested a noninvasive ultrasound, Pulse Phase Locked Loop (PPLL) technique for estimating Intramuscular Pressure (IMP) in a model Acute Compartment Syndrome (ACS); and compared it to a Near-Infrared Spectroscopy (NIRS) method.\u0000\u0000\u0000QUESTIONS\u0000We wanted to validate our model compartment syndrome, and to compare and validate the PPLL and NIRS methods of detecting compartment syndrome.\u0000\u0000\u0000METHODS\u0000To simulate the tamponade of an ACS, external-pressure levels from 10 to 70 mm Hg were applied to the legs of 15 healthy adult subjects to raise their IMP. Receiver Operator Characteristic (ROC) curves were used to determine the sensitivity and specificity of diagnosing elevated IMP by the two noninvasive techniques.\u0000\u0000\u0000RESULTS\u0000NIRS data varied significantly with compression (p=0.003) with large subject-to-subject variability (p<0.001). PPLL data also varied significantly with compression (p=0.004), but subject-to-subject variation was not significant (p=0.47), suggesting that individual variation does not affect the diagnostic accuracy of the PPLL technique. Sensitivity and specificity for diagnosing normal IMP by the PPLL (<30 mm Hg from a slit catheter reading) from elevated IMP (>30 mm Hg) were 0.75 and 0.75, respectively, and the area under the curve (AUC) was 0.78. For the NIRS, the sensitivity and specificity were 0.65 and 0.65, respectively, and the AUC was 0.68.\u0000\u0000\u0000CONCLUSIONS\u0000Both NIRS and PPLL recordings are able to differentiate a simulated ACS up to 70 mm Hg. However, the PPLL technique is a slightly better diagnostic predictor than NIRS with less subject-to-subject variability and slightly better sensitivity and specificity.\u0000\u0000\u0000LEVEL OF EVIDENCE\u0000Level II, Diagnostic test.","PeriodicalId":90612,"journal":{"name":"Journal of orthopedics & rheumatology","volume":"96 1","pages":"5"},"PeriodicalIF":0.0,"publicationDate":"2013-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66210105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samantha H Lee, Michael Padilla, John E Lynch, Alan R Hargens
{"title":"Noninvasive Measurements of Pressure for Detecting Compartment Syndromes.","authors":"Samantha H Lee, Michael Padilla, John E Lynch, Alan R Hargens","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>We tested a noninvasive ultrasound, Pulse Phase Locked Loop (PPLL) technique for estimating Intramuscular Pressure (IMP) in a model Acute Compartment Syndrome (ACS); and compared it to a Near-Infrared Spectroscopy (NIRS) method.</p><p><strong>Questions: </strong>We wanted to validate our model compartment syndrome, and to compare and validate the PPLL and NIRS methods of detecting compartment syndrome.</p><p><strong>Methods: </strong>To simulate the tamponade of an ACS, external-pressure levels from 10 to 70 mm Hg were applied to the legs of 15 healthy adult subjects to raise their IMP. Receiver Operator Characteristic (ROC) curves were used to determine the sensitivity and specificity of diagnosing elevated IMP by the two noninvasive techniques.</p><p><strong>Results: </strong>NIRS data varied significantly with compression (p=0.003) with large subject-to-subject variability (p<0.001). PPLL data also varied significantly with compression (p=0.004), but subject-to-subject variation was not significant (p=0.47), suggesting that individual variation does not affect the diagnostic accuracy of the PPLL technique. Sensitivity and specificity for diagnosing normal IMP by the PPLL (<30 mm Hg from a slit catheter reading) from elevated IMP (>30 mm Hg) were 0.75 and 0.75, respectively, and the area under the curve (AUC) was 0.78. For the NIRS, the sensitivity and specificity were 0.65 and 0.65, respectively, and the AUC was 0.68.</p><p><strong>Conclusions: </strong>Both NIRS and PPLL recordings are able to differentiate a simulated ACS up to 70 mm Hg. However, the PPLL technique is a slightly better diagnostic predictor than NIRS with less subject-to-subject variability and slightly better sensitivity and specificity.</p><p><strong>Level of evidence: </strong>Level II, Diagnostic test.</p>","PeriodicalId":90612,"journal":{"name":"Journal of orthopedics & rheumatology","volume":"1 1","pages":"5"},"PeriodicalIF":0.0,"publicationDate":"2013-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197938/pdf/nihms593633.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32758134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Dynamic Duo-Inflammatory M1 macrophages and Th17 cells in Rheumatic Diseases.","authors":"Jun Li, Hui-Chen Hsu, John D Mountz","doi":"10.13188/2334-2846.1000002","DOIUrl":"https://doi.org/10.13188/2334-2846.1000002","url":null,"abstract":"<p><p>The synovial tissue of Rheumatoid Arthritis (RA) patients is enriched with macrophages and T lymphocytes which are two central players in the pathogenesis of RA. Interaction between myeloid cells and T cells are essential for the initiation and progression of the inflammatory processes in the synovium. With the rapid evolution of our understanding of how these two cell types are involved in the regulation of immune responses, RA is emerging as an ideal disease model for investigating the cell-cell interactions and consequently introducing novel biologic agents that are designed to disrupt these processes. This review will discuss the bidirectional interaction between the IL-23<sup>+</sup> inflammatory macrophages and IL-17<sup>+</sup> GM-CSF<sup>+</sup> CD4 T cells in rheumatic diseases as well as potential antirheumatic strategies via apoptosis induction in this context.</p>","PeriodicalId":90612,"journal":{"name":"Journal of orthopedics & rheumatology","volume":"1 1","pages":"4"},"PeriodicalIF":0.0,"publicationDate":"2013-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193941/pdf/nihms561277.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32742702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}