The open medical imaging journal最新文献_第4页

QGATE: An Educational Environment to Learn and Perform Nuclear Medicine Imaging Simulation with GATE QGATE:使用GATE学习和执行核医学成像模拟的教育环境

The open medical imaging journal Pub Date : 2011-12-22 DOI: 10.2174/1874347101105010026

Xiping Li, Weizhao Zhao

{"title":"QGATE: An Educational Environment to Learn and Perform Nuclear Medicine Imaging Simulation with GATE","authors":"Xiping Li, Weizhao Zhao","doi":"10.2174/1874347101105010026","DOIUrl":"https://doi.org/10.2174/1874347101105010026","url":null,"abstract":"Geant4 Application for Tomographic Emission (GATE) is a commonly used platform developed for nuclear medicine imaging simulation. It has been used to investigate imaging system's sensitivity, data acquisition methods, or image reconstruction algorithms. The GATE system, based on the Monte Carlo method, operates relying on user-provided scripts that follow the program definitions in the system's command library. Script-writing is usually time-consuming and frequently error-associated unless one has had certain experience in the simulation field and is familiar with programming. This is obviously an obstacle to students and beginners. The learning curve of script-writing is relatively flat to non- programming background learners. In addition, the GATE system is commonly installed on a high-performance computer, on which the scripts are usually compiled and used by the user only. In order to utilize GATE's potential to be a routine simulation toolkit, we have developed QGATE, a GUI-based GATE system. The QGATE system provides users a graphi- cal environment where a simulation design is achieved by fashions like \"drag-and-drop objects\" and \"choose-and-modify parameters\". The scripts will be automatically generated and complied by the system. Parameters belonging to each object have default values so as to avoid errors induced by new users. The QGATE system consists of one or more QGATE Cli- ents and one QGATE Server. The Client can be installed on individual computers so that multiple users can work on their simulation projects simultaneously by using the graphical designing tools. The Server is installed on the same computer as the GATE system resides. The Server manages the submitted simulation scripts queued by a job ticket and returns the job finish signal to the corresponding client. The QGATE system is suitable for classroom training and easy to use for stu- dents or new users to the field of nuclear medicine imaging simulation.","PeriodicalId":90366,"journal":{"name":"The open medical imaging journal","volume":"8 1","pages":"26-33"},"PeriodicalIF":0.0,"publicationDate":"2011-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75436587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Generation of Functional Images of The Brain Trapping Constant for α-[11C]Methyl-L-Tryptophan Using Constrained Linear Regression 用约束线性回归生成α-[11C]甲基- l-色氨酸脑捕获常数的功能图像

The open medical imaging journal Pub Date : 2011-10-07 DOI: 10.2174/1874347101105010014

Y. Kumakura, J. Natsume, P. Toussaint, A. Nakai, P. Rosa-Neto, E. Meyer, M. Diksic

{"title":"Generation of Functional Images of The Brain Trapping Constant for α-[11C]Methyl-L-Tryptophan Using Constrained Linear Regression","authors":"Y. Kumakura, J. Natsume, P. Toussaint, A. Nakai, P. Rosa-Neto, E. Meyer, M. Diksic","doi":"10.2174/1874347101105010014","DOIUrl":"https://doi.org/10.2174/1874347101105010014","url":null,"abstract":"The main objective of described work was a generation of the functional images of the brain trapping constant (K*; μL/g/min) of -methyl-L-tryptophan, an index of 5-HT synthesis, which under some assumptions is related to the serotonin synthesis. Comparisons of the regional K* calculated by the Patlak approximation, non-linear fitting and the linearized form of the non-linear operational equation were made and discussed. In addition a contrast between the white and gray matter K* values was evaluated by different methods. Results presented suggest that the linearized form of the operational equation yields the best gray to white matter contrast. It was also shown that with this calculation approach, as was shown before for the Patlak approximation, the use of the venous sinus-venous blood normalized input function instead of the arterial input function is satisfactory. Also results show that the error of the K* estimates is smaller than those in the Patlak estimates, when the linearized solution of the model equation is used. Simulation results indicate that the coefficient of variation for K* is smaller than some errors for the equation parameters.","PeriodicalId":90366,"journal":{"name":"The open medical imaging journal","volume":"25 1","pages":"14-25"},"PeriodicalIF":0.0,"publicationDate":"2011-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83289370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Comparison of Chest Dual-Energy Subtraction Digital Tomosynthesis and Conventional Digital Tomosynthesis for the Detection of Simulated Pulmonary Nodules with Calcifications: Phantom Study 胸部双能量减影数字断层合成与传统数字断层合成对带钙化的模拟肺结节检测的比较:幻象研究

The open medical imaging journal Pub Date : 2011-05-24 DOI: 10.2174/1874347101105010008

T. Gomi, M. Nakajima, H. Fujiwara

{"title":"Comparison of Chest Dual-Energy Subtraction Digital Tomosynthesis and Conventional Digital Tomosynthesis for the Detection of Simulated Pulmonary Nodules with Calcifications: Phantom Study","authors":"T. Gomi, M. Nakajima, H. Fujiwara","doi":"10.2174/1874347101105010008","DOIUrl":"https://doi.org/10.2174/1874347101105010008","url":null,"abstract":"To compare the effectiveness of chest dual-energy subtraction digital tomosynthesis (DES-DT) with that of conventional digital tomosynthesis for the detection of calcifications superimposed over simulated pulmonary nodules. A DES-DT system with pulsed X-rays and rapid kV switching was used to examine calcifications in simulated pulmonary nodules. Low-voltage, high-voltage, and soft-tissue or bone-subtracted tomograms of the desired layer thicknesses were reconstructed from the image data acquired during a single tomographic scan, bone-subtracted images, and a scan angle of 40°. Our analysis took into account the signal-to-noise ratio (SNR) of the different degrees of calcification in the simulated pulmonary nodules. For DES-DT, the SNR for the simulated pulmonary nodules increased about 63%. Based on the results of receiver operating characteristic performance analysis, the detection ability of our DES-DT was significantly better than that of conventional digital tomosynthesis (P < 0.03). The study results confirmed with a further study to assess influence of reconstruction and filtering for detection of simulated nodules. DES-DT provided greater sensitivity than conventional digital tomosynthesis.","PeriodicalId":90366,"journal":{"name":"The open medical imaging journal","volume":"51 1","pages":"8-13"},"PeriodicalIF":0.0,"publicationDate":"2011-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73464361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Real-time magnetic resonance imaging of temporomandibular joint dynamics. 颞下颌关节动态的实时磁共振成像。

The open medical imaging journal Pub Date : 2011-03-10 DOI: 10.2174/1874347101105010001

Shuo Zhang, N. Gersdorff, J. Frahm

{"title":"Real-time magnetic resonance imaging of temporomandibular joint dynamics.","authors":"Shuo Zhang, N. Gersdorff, J. Frahm","doi":"10.2174/1874347101105010001","DOIUrl":"https://doi.org/10.2174/1874347101105010001","url":null,"abstract":"This study evaluated the use of a novel real-time MRI technique based on fast low angle shot (FLASH) MRI with radial encoding, gridding reconstruction, and sliding window for the assessment of temporomandibular joint (TMJ) dynamics in a cohort of 30 young volunteers without prior diagnosis of TMJ pathology. High-resolution images (0.75 ￻ 0.75 mm 2 , 5 mm section thickness) were obtained at 3 frames per second for active jaw movements without adjunctive devices. Real-time movies were evaluated with respect to image artefacts, anatomical visibility, diagnostic confidence, and TMJ function. During the entire opening and closing of the mouth, the relative positions of the mandibular condyle and articular disc were well depicted. Mean scores were 1.01 ± 0.65 for motion artefacts (scale: 0 = no to 3 = severe artefacts) and 2.03 ± 0.71 for anatomical detectability (scale: 1 = excellent to 5 = not visible). High inter-observer agreements were found for assessments of mandibular condyle movements (� = 0.83) and articular disc displacements (� = 0.91). In latter cases, the point of disc reduction could precisely be identified. In conclusion, the proposed real-time MRI method offers robust access to TMJ dynamics with good image quality.","PeriodicalId":90366,"journal":{"name":"The open medical imaging journal","volume":"64 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2011-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78791678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 30

Quantitative Diffusion Tensor Imaging of White Matter Microstructure in Dog Brain at 7T 犬7T脑白质微观结构的定量扩散张量成像

The open medical imaging journal Pub Date : 2011-01-01 DOI: 10.2174/1874347101004010001

Ping Wang, Jian-Ming Zhu

引用次数: 8

A Patient with Everolimus-Associated Pneumonitis 依维莫司相关性肺炎1例

The open medical imaging journal Pub Date : 2009-12-11 DOI: 10.2174/1874347100903010028

C. Intemann, G. Goerres

引用次数: 0

Separation of fiber tracts within the human cingulum bundle using single-shot STEAM DTI. 使用单次蒸汽DTI分离人类扣带束内的纤维束。

The open medical imaging journal Pub Date : 2009-12-11 DOI: 10.2174/1874347100903010021

A. Karaus, S. Hofer, J. Frahm

引用次数: 9

A Review of Imaging in Psychiatry 精神病学影像学研究综述

The open medical imaging journal Pub Date : 2009-05-11 DOI: 10.2174/1874347100903010015

J. Lagopoulos, P. Das, O. Sæther, G. Malhi

引用次数: 3

Quantifying Uncertainties for Prostate Image-Guided Radiotherapy: A 3D Organ Reconstruction and Registration Method 前列腺影像引导放射治疗的不确定度量化:一种三维器官重建与配准方法

The open medical imaging journal Pub Date : 2009-04-10 DOI: 10.2174/1874347100903010001

X. Gual-Arnau, R. Masó, F. Lliso, J. López-Tarjuelo

引用次数: 0

Topographical Organization of the Pyramidal Fiber System Diffusion Tensor MRI of the Human and Rhesus Monkey Brain 人和恒河猴脑锥体纤维系统弥散张量MRI的地形组织

The open medical imaging journal Pub Date : 2009-04-07 DOI: 10.2174/1874347100903010006

S. Hofer, J. Frahm

{"title":"Topographical Organization of the Pyramidal Fiber System Diffusion Tensor MRI of the Human and Rhesus Monkey Brain","authors":"S. Hofer, J. Frahm","doi":"10.2174/1874347100903010006","DOIUrl":"https://doi.org/10.2174/1874347100903010006","url":null,"abstract":"The fibers of the pyramidal tract (PT) that connect the precentral and postcentral gyrus with the spinal cord are organized in a topological manner. However, their exact arrangement and orientation in the internal capsule is still a mat- ter of debate. Here, we applied magnetic resonance diffusion tensor imaging and tract tracing techniques to determine and compare the pyramidal fibers from the primary motor and somatosensory system in humans and rhesus monkeys in vivo. The results demonstrate that the pyramidal systems of the human and monkey brain differ in their orientation at the level of the internal capsule, whereas track orientations in the gyrus and brainstem appear similar. In the monkey internal cap- sule the somatotopic arrangement of PT fibers from the upper and lower extremities form an angle with the left-right axis of 146° ± 23° (n=4). Thus, fibers from lateral areas of the gyrus are located more anterior-medial to fibers from medial cortical areas. In contrast, in humans the angle is only 50° ± 16° (n=9) yielding a more anterior-lateral orientation of PT fibers along the short axis of the internal capsule. These species dependencies may possibly be due to structural con- straints of the smaller and differently shaped monkey brain.","PeriodicalId":90366,"journal":{"name":"The open medical imaging journal","volume":"17 1","pages":"6-14"},"PeriodicalIF":0.0,"publicationDate":"2009-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77660109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1