The open medical imaging journal最新文献_第6页

Is there Still Enough Diagnostic Confidence with Bone Spect Scintigraphy Alone: A Retrospective Evaluation and Extended Review of the Literature 骨显像是否仍有足够的诊断信心:回顾性评价和文献综述

The open medical imaging journal Pub Date : 2008-02-06 DOI: 10.2174/1874347100802010007

S. Gratz, H. Höffken, W. Kaiser, K. Klose, T. Behr

{"title":"Is there Still Enough Diagnostic Confidence with Bone Spect Scintigraphy Alone: A Retrospective Evaluation and Extended Review of the Literature","authors":"S. Gratz, H. Höffken, W. Kaiser, K. Klose, T. Behr","doi":"10.2174/1874347100802010007","DOIUrl":"https://doi.org/10.2174/1874347100802010007","url":null,"abstract":"Aim: Single photon emission computed tomography (SPECT) dramatically increases the sensitivity of bone scanning for detection of spinal abnormalities. However, the level of specificity obtained by SPECT remains controversial and increased diagnostic confidence can be obtained with new imaging modalities such as fused PET/CT and SPECT/CT. Patients and Methods: Between 7/2005 and 7/2007 ninety one patients with different malignant primary tumors were in- vestigated. Following injection of 555 MBq 99m Tc - MDP planar and SPECT images were performed in all patients. Re- sults: Out of a total of 145 spinal lesions was confirmed by radiography, SPECT detected 133 (91%). In contrast, planar scintigraphy detected only 99/145 (68%) lesions. SPECT uptake pattern including the vertebral body and an adjacent pedicle was seen in 9/28 (32%) of metastatic lesions and in 1/2 (50%) cases of spondylitis. SPECT uptake pattern includ- ing the pedicle alone was seen in 45/115 (39%) of degenerative alterations. Focal lesions limited to the lateral part of the vertebral body, especially to the pars interarticularis (n=8), facet joints (n=14) and costotransversal joints (n=6), were cor- rectly diagnosed as spondylarthrosis and costotransversalarthrosis in all cases. Furthermore, SPECT uptake pattern of spondylitis was biconcave, whereas metastatic lesions showed focal or linear uptakes. Conclusion: SPECT without image fusion still gives sufficient diagnostic confidence for the differentiation of benign and malignant spine lesions. Uptake pat- terns localized at the facet joints or localized at the pedicles are indicative for benign lesions, whereas continuous uptake patterns of the vertebral body and adjacent pedicle remain suspicious for malignancy.","PeriodicalId":90366,"journal":{"name":"The open medical imaging journal","volume":"65 1","pages":"7-13"},"PeriodicalIF":0.0,"publicationDate":"2008-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84747491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Differentiation of Tuberculous and Pyogenic Spondylitis Using Double Phase F-18 FDG PET F-18 FDG PET鉴别结核性和化脓性脊柱炎

The open medical imaging journal Pub Date : 2008-01-03 DOI: 10.2174/1874347100802010001

Seong-Jang Kim, J. S. Lee, K. Suh, In‐Ju Kim, Yong‐Ki Kim

{"title":"Differentiation of Tuberculous and Pyogenic Spondylitis Using Double Phase F-18 FDG PET","authors":"Seong-Jang Kim, J. S. Lee, K. Suh, In‐Ju Kim, Yong‐Ki Kim","doi":"10.2174/1874347100802010001","DOIUrl":"https://doi.org/10.2174/1874347100802010001","url":null,"abstract":"To assess the usefulness of double phase F-18 FDG PET in pyogenic spondylitis (PS) and tuberculous spondylitis (TS). Also, to investigate whether double phase F-18 FDG PET could improve the diagnostic accuracy for discrimination of PS from TS. Methods: Double phase F-18 FDG PET/CT was performed in a consecutive 23 patients (9 men, 14 women; mean age, 58.5±17.9 years, range, 19~81 years) suspected having spondylitis. PET/CT imaging was performed 60 and 120 minutes after injection of F-18 FDG.. Results: The SUVmax1 of TS and PS showed no statistical differences (TS, 4.53 1.77; PS, 4.5 1.9, p=0.9515). The SUVmax2 also showed no statistical differences between two groups (TS, 5.17 1.95; PS, 5.3 2.21, p=0.9321). The mean SUV of early and delayed F-18 FDG PET images revealed no statistical differences between TS and PS. The % SUVmax and % SUVmean have no statistical differences between TS and PS (% SUVmax, TS, 15.07 6.57%, PS, 18.79 10.48%, p=0.5109; % SUVmean, TS, 16.49 9.1%, PS, 16.88 6.72%, p=0.6524). Also, none of these quantitative indices could differentiate the TS from PS. Furthermore, none of these quantitative indices could predict the presence of TS. Conclusion: Based on the presented data, the quantitative indices of double phase F-18 FDG PET could not differentiate TS from PS despite of high sensitivity for the detection of spondylitis of F-18 FDG PET.","PeriodicalId":90366,"journal":{"name":"The open medical imaging journal","volume":"119 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2008-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85635018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Non-Invasive Estimation of Subcutaneous and Visceral Adipose Tissue Blood Flow by Using [15O]H2O PET with Image Derived Input Functions [15O]H2O PET与图像衍生输入函数的无创估计皮下和内脏脂肪组织血流量

The open medical imaging journal Pub Date : 2007-12-06 DOI: 10.2174/1874347100701010007

K. Liukko, V. Oikonen, T. Tolvanen, K. Virtanen, Antti Viljanen, H. Sipilä, P. Nuutila, P. Iozzo

{"title":"Non-Invasive Estimation of Subcutaneous and Visceral Adipose Tissue Blood Flow by Using [15O]H2O PET with Image Derived Input Functions","authors":"K. Liukko, V. Oikonen, T. Tolvanen, K. Virtanen, Antti Viljanen, H. Sipilä, P. Nuutila, P. Iozzo","doi":"10.2174/1874347100701010007","DOIUrl":"https://doi.org/10.2174/1874347100701010007","url":null,"abstract":"Subcutaneous adipose tissue blood flow is finely regulated, and tuned with fat metabolism; little is known about visceral fat, which is less accessible in humans. In estimating blood flow with positron emission tomography (PET) and oxygen-15-labelled water (( 15 O)H2O), the input function is obtained invasively from arterial blood samples. The aim of the current study was to validate a non-invasive method to measure blood flow in adipose depots, by extracting input function curves from ( 15 O)H2O-PET images. Data of twenty subjects undergoing abdominal ( 15 O)H2O-PET were used. Images were reconstructed with filtered backprojection (FBP). Location, diameter, and inner radioactivity levels of the abdominal aorta were automatically determined. Image derived arterial curves (IDI) were compared to measured arterial blood data, as obtained by an online blood sampler (OSI). Blood flow in three adipose tissue depots was estimated using the autoradiographic method with OSI vs the FBP image derived input (F-IDI) function. Correlations between blood flow results obtained with OSI and IDI were significant (r￻ 0.87, p<0.0001) in all regions. Estimates of the aortic diameter ranged between 10.7-17.2 mm. A good agreement was found between area under the curve (AUC) values of F-IDI and OSI curves; the AUCF-IDI/AUCOSI ratio was 0.97±0.10. Our results support the implementation of the current method for the non-invasive detection of the abdominal aorta input function from a dynamic ( 15 O)H2O PET image in the quantifica- tion of regional blood flow in low flow tissues. This method allows simultaneously examine subcutaneous and intra- abdominal fat depots.","PeriodicalId":90366,"journal":{"name":"The open medical imaging journal","volume":"7 1","pages":"7-13"},"PeriodicalIF":0.0,"publicationDate":"2007-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87339091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Design an Adaptive Quality Control Phantom to Optimize QC Test Methods 设计一个自适应质量控制模型以优化质量控制测试方法

The open medical imaging journal Pub Date : 2007-11-27 DOI: 10.2174/1874347100701010001

H. Zeinali, M. Ghiassi-nejad, A. Mirzaii

{"title":"Design an Adaptive Quality Control Phantom to Optimize QC Test Methods","authors":"H. Zeinali, M. Ghiassi-nejad, A. Mirzaii","doi":"10.2174/1874347100701010001","DOIUrl":"https://doi.org/10.2174/1874347100701010001","url":null,"abstract":"The main objective of this research is to introduce a newly developed device called as \"Adaptive Quality Control Phantom\" (AQCP) that designed to perform the QC tests. AQCP is a computer-controlled phantom which positions and moves a radioactive source in the FOV of an imaging nuclear medicine device on a definite path to produce any spatial distribution of gamma rays to simulate QC phantoms. To establish and prove the proper functionality as well as the accurate performance of AQCP, different tests including systematic uniformity, collimator hole angulation and the center of rotation tests have been conducted by this device and then the results, findings and differences of such testing when comparing to what achieved by the QC classic method tests have been discussed and analyzed in detail in this paper. According to the different tests done by AQCP, the authors found that the performance of systematic uniformity test shows a considerable reduction in the technologist dose compared to the IAEA-TECDOC-602 method. The collimator hole angulation for LEHR, LEUHR and LEHS collimators were measured by using a point source and the computer-controlled cylindrical positioning and the results achieved indicate that the measurement accuracy for absolute angulation errors was better than 0.018 degrees. A method for center of rotation assessment by AQCP was introduced, the results of such proposed method compared to the routine QC test and their differences have been discussed in detail. Based on all discussed in this paper regarding AQCP, the authors suggest that their presented device would be able to simulate QC phantoms.","PeriodicalId":90366,"journal":{"name":"The open medical imaging journal","volume":"1 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2007-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82943262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3