Norman McCulloch MD , Susan M. Wojcik PhD , Marvin Heyboer III MD
{"title":"Patient Outcomes and Factors Associated with Healing in Calciphylaxis Patients Undergoing Adjunctive Hyperbaric Oxygen Therapy","authors":"Norman McCulloch MD , Susan M. Wojcik PhD , Marvin Heyboer III MD","doi":"10.1016/j.jccw.2016.08.004","DOIUrl":"https://doi.org/10.1016/j.jccw.2016.08.004","url":null,"abstract":"<div><p><span><span>Calcific uremic arteriolopathy, also known as calciphylaxis, is a rare syndrome of small vessel calcification of unknown etiology causing painful, violaceous </span>skin lesions<span><span> that progress to form chronic non-healing ulcers<span> and gangrene. Hyperbaric oxygen therapy (HBOT) can be used as adjunctive therapy in the </span></span>treatment of these ulcers. However, due to paucity of cases, there is limited data on the clinical benefit of HBOT and identifying factors associated with healing. The purpose of this study was to determine patient outcomes and factors associated with healing </span></span>in patients<span><span><span> with calciphylaxis undergoing HBOT. A retrospective chart review was completed on patients who were diagnosed with calciphylaxis and had hyperbaric medicine consultation between May 2012 and January 2016. Clinical outcomes, demographics, risk factors, laboratory values, wound distribution, and HBOT profiles were collected and analyzed. We identified 8 patients. Out of 8 patients consulted for calciphylaxis, five were consented and underwent HBOT (2 males and 3 females). All had coexisting ESRD and Diabetes. All males were able to tolerate being in the chamber and received therapeutic treatments (at least 20 HBOT) with complete resolution of ulcers. HBOT was discontinued in one female due to an inconsistent biopsy report and two others due to death secondary to </span>septic shock or respiratory arrest and severe </span>uremia. Calciphylaxis is a devastating disease with a high mortality rate. Our results demonstrated a positive response to HBOT especially when receiving at least 20 treatments. A majority of calciphylaxis cases are females and indeed female gender has been cited as a risk factor for this disease. However, current literature has not conferred a relationship between gender nor the number of HBOT received and outcomes. Our results showed that males had a more favorable outcome provided they received at least twenty HBOT. Further prospective studies are needed to elucidate these outcomes.</span></p></div>","PeriodicalId":90358,"journal":{"name":"The journal of the American College of Clinical Wound Specialists","volume":"7 1","pages":"Pages 8-12"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jccw.2016.08.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72256043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Walid Mari MD, Sami G. Alsabri BSc Pharm, Najib Tabal MD, Sara Younes MD, Abdulamagid Sherif MD, Richard Simman MD, FACS, FACCWS
{"title":"Novel Insights on Understanding of Keloid Scar: Article Review","authors":"Walid Mari MD, Sami G. Alsabri BSc Pharm, Najib Tabal MD, Sara Younes MD, Abdulamagid Sherif MD, Richard Simman MD, FACS, FACCWS","doi":"10.1016/j.jccw.2016.10.001","DOIUrl":"https://doi.org/10.1016/j.jccw.2016.10.001","url":null,"abstract":"<div><p>Keloid scar<span>, dermal benign fibro-proliferative growth that extends outside the original wound and invades adjacent dermal tissue due to extensive production of extracellular matrix<span><span><span><span>, especially collagen, which caused by over expression of cytokines and growth factors. Although many attempts were made to understand the exact pathophysiology and the molecular abnormalities, the pathogenesis of keloid scar is yet to be determined. Even though there are several </span>treatment<span> options for keloid scars include combination of medical and surgical therapies like combination of surgical removal followed by cryotherapy or intralesional </span></span>steroid therapy, the reoccurrence rate is still high despite the present treatment. In this review, PubMed, clinical key and Wright State Library web site have been used to investigate any update regarding Keloid disease. We used Keloid, scar formation, </span>hypertrophic scar<span> and collagen as key words. More than 40 articles have been reviewed. This paper reviews literature about keloid scar formation mechanism, the most recent therapeutic options including the ones under research.</span></span></span></p></div>","PeriodicalId":90358,"journal":{"name":"The journal of the American College of Clinical Wound Specialists","volume":"7 1","pages":"Pages 1-7"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jccw.2016.10.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72256044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alejandra Vidal, H. Mendieta Zerón, Israel Giacaman, María del Socorro Camarillo Romero, Sandra Parra López, Laura E Meza Trillo, David A Pérez Pérez, M. Concha, César Torres-Gallegos, Sandra L. Orellana, F. Oyarzun-Ampuero, I. Moreno‐Villoslada
{"title":"A Simple Mathematical Model for Wound Closure Evaluation.","authors":"Alejandra Vidal, H. Mendieta Zerón, Israel Giacaman, María del Socorro Camarillo Romero, Sandra Parra López, Laura E Meza Trillo, David A Pérez Pérez, M. Concha, César Torres-Gallegos, Sandra L. Orellana, F. Oyarzun-Ampuero, I. Moreno‐Villoslada","doi":"10.1016/j.jccw.2016.07.002","DOIUrl":"https://doi.org/10.1016/j.jccw.2016.07.002","url":null,"abstract":"","PeriodicalId":90358,"journal":{"name":"The journal of the American College of Clinical Wound Specialists","volume":"33 1","pages":"40-49"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85656175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Donald E Mrdjenovich, R. Simman, C. Fleck, Tammy Luttrell
{"title":"The American College of Clinical Wound Specialists (ACCWS) Rebuttal to the Recent NPUAP Pressure Ulcer Definition (July 2016).","authors":"Donald E Mrdjenovich, R. Simman, C. Fleck, Tammy Luttrell","doi":"10.1016/j.jccw.2016.08.002","DOIUrl":"https://doi.org/10.1016/j.jccw.2016.08.002","url":null,"abstract":"","PeriodicalId":90358,"journal":{"name":"The journal of the American College of Clinical Wound Specialists","volume":"73 1","pages":"53"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86014443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Director of ACCWS Board Promoting Mission of College by Advocating for Public Health of Diabetic Foot Care Awareness and Amputation Prevention.","authors":"C. Fleck","doi":"10.1016/j.jccw.2016.08.001","DOIUrl":"https://doi.org/10.1016/j.jccw.2016.08.001","url":null,"abstract":"","PeriodicalId":90358,"journal":{"name":"The journal of the American College of Clinical Wound Specialists","volume":"142 1","pages":"54-55"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76603383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
W. Mari, S. G. Alsabri, Najib Tabal, S. Younes, Abdulamagid Sherif, R. Simman
{"title":"Novel Insights on Understanding of Keloid Scar: Article Review.","authors":"W. Mari, S. G. Alsabri, Najib Tabal, S. Younes, Abdulamagid Sherif, R. Simman","doi":"10.1016/j.jccw.2016.10.001","DOIUrl":"https://doi.org/10.1016/j.jccw.2016.10.001","url":null,"abstract":"","PeriodicalId":90358,"journal":{"name":"The journal of the American College of Clinical Wound Specialists","volume":"2013 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88188018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tammy C. Luttrell PhD, Hasan Khashwj MD, Nicole Ingalls MD, Jay Coates DO
{"title":"Challenges of Complex Open Abdominal Wound Management in Trauma: A Novel Use of Chitosan and Hyaluronic Acid as a 3-Dimensional Scaffold to Overcome Resilient Open Abdomen Infections","authors":"Tammy C. Luttrell PhD, Hasan Khashwj MD, Nicole Ingalls MD, Jay Coates DO","doi":"10.1016/j.jccw.2016.02.001","DOIUrl":"https://doi.org/10.1016/j.jccw.2016.02.001","url":null,"abstract":"<div><p><span>Case presentation of a novel method for the management of complex open abdomen technique. This Mmethod includes the combination of chitosan, hyaluronic acid and </span>negative pressure wound therapy. Patient was initially managed with traditional operating room wash-outs and packing. Implementation of novel method achieved closure in 17 days with split-thickness-skin-graft.</p></div>","PeriodicalId":90358,"journal":{"name":"The journal of the American College of Clinical Wound Specialists","volume":"7 1","pages":"Pages 25-29"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jccw.2016.02.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72256042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Susan E. Wozniak MD, MBA, Stephanie Zuo BA, Kamran Khan MD, JoAnn Coleman DNP, ACNP-BC
{"title":"Old War Scar Revisited","authors":"Susan E. Wozniak MD, MBA, Stephanie Zuo BA, Kamran Khan MD, JoAnn Coleman DNP, ACNP-BC","doi":"10.1016/j.jccw.2016.09.001","DOIUrl":"10.1016/j.jccw.2016.09.001","url":null,"abstract":"<div><p>In 1828, Jean Nicholas Marjolin, a French surgeon, first described the findings of a neoplastic development arising from a burn scar, now more commonly referred to as a Marjolin's ulcer. A Marjolin's ulcer describes malignant degeneration in any chronic wound. The majority of cases arises in burn scars and are often latent for decades. Marjolin ulcers have been widely identified in post-war time injuries. These ulcers may arise in almost any anatomical location. We report a case of an 82-year-old male that presented with a painful fluctuating mass on the right arm localized to the site of an old grenade blast injury he sustained many years earlier. While the presentation of these cases may be variable, the significance of proper management of the wounds is essential to optimal patient outcomes. An aggressive course and poor prognosis is associated with Marjolin's ulcers that degenerate into squamous cell carcinoma. Early detection and aggressive treatment/management with wide local excision and prompt coverage yield the best results when treating patients with Marjolin's ulcers.</p></div>","PeriodicalId":90358,"journal":{"name":"The journal of the American College of Clinical Wound Specialists","volume":"7 1","pages":"Pages 35-39"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jccw.2016.09.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74396956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alejandra Vidal MD , Hugo Mendieta Zerón PhD , Israel Giacaman , María del Socorro Camarillo Romero PhD , Sandra Parra López , Laura E. Meza Trillo MD , David A. Pérez Pérez , Miguel Concha PhD , César Torres-Gallegos , Sandra L. Orellana PhD , Felipe Oyarzun-Ampuero PhD , Ignacio Moreno-Villoslada PhD
{"title":"A Simple Mathematical Model for Wound Closure Evaluation","authors":"Alejandra Vidal MD , Hugo Mendieta Zerón PhD , Israel Giacaman , María del Socorro Camarillo Romero PhD , Sandra Parra López , Laura E. Meza Trillo MD , David A. Pérez Pérez , Miguel Concha PhD , César Torres-Gallegos , Sandra L. Orellana PhD , Felipe Oyarzun-Ampuero PhD , Ignacio Moreno-Villoslada PhD","doi":"10.1016/j.jccw.2016.07.002","DOIUrl":"https://doi.org/10.1016/j.jccw.2016.07.002","url":null,"abstract":"<div><p>The incidence of ulcers<span> associated to type 2 diabetes mellitus<span> (T2DM) increases every year. We introduce and explore a new mathematical algorithm to evaluate wound-healing in foot ulcers associated to T2DM. Fifteen patients (nine women and six men), mean age of 70 ± 16 years were included. The evolution of their wounds followed-up for a period of 18–45 days. According to the Wagner grading system the ulcers were grade I (5 patients), grade II (9 patients), and grade III (1 patient). Clinically, the type of the ulcers was neuroischemic (12 patients) and neuropathic (3 patients). A new parameter is introduced, the “continuous linear healing rate” Dc that was more accurate with higher values and requires less quantifications than usual formulas to make a wound-healing projection.</span></span></p></div>","PeriodicalId":90358,"journal":{"name":"The journal of the American College of Clinical Wound Specialists","volume":"7 1","pages":"Pages 40-49"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jccw.2016.07.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72256067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The NPUAP Meeting – This was No Consensus Conference","authors":"Joy E. Schank RN, MSN, ANP, CWOCN","doi":"10.1016/j.jccw.2016.07.001","DOIUrl":"10.1016/j.jccw.2016.07.001","url":null,"abstract":"<div><p><span><span>The National Pressure Ulcer Advisory Panel (NPUAP) held a Consensus Conference on Pressure Ulcer Staging April 8–9, 2016 in Chicago, Illinois. This was conducted by a moderator and six NPUAP members who were designated as the staging task force. This consisted of 4 nurses, 2 of which were nurse practitioners, one </span>dietician and an individual with a Ph.D. in mechanical and aerospace engineering. Their purpose was “to revise the staging definitions to further clarify and refine the system and develop new nomenclature relevant to pressure related soft tissue injury” (Consensus Conference on Pressure Ulcer Staging, 2016). Many of the changes were not made by consensus but were predetermined by the task force. This includes the following changes. Pressure ulcers are now </span>pressure injuries<span><span>. The stages are described with Arabic numbers rather than Roman numerals. There are two new pressure categories – medical device related pressure injury and </span>mucosal membrane pressure injury. New artwork has been created to depict the stages. There were changes made to all the stages, but only some of this was by consensus. These revisions were announced by press release on April 13, 2016.</span></p></div>","PeriodicalId":90358,"journal":{"name":"The journal of the American College of Clinical Wound Specialists","volume":"7 1","pages":"Pages 19-24"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jccw.2016.07.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87811166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}