Alejandra Vidal MD , Hugo Mendieta Zerón PhD , Israel Giacaman , María del Socorro Camarillo Romero PhD , Sandra Parra López , Laura E. Meza Trillo MD , David A. Pérez Pérez , Miguel Concha PhD , César Torres-Gallegos , Sandra L. Orellana PhD , Felipe Oyarzun-Ampuero PhD , Ignacio Moreno-Villoslada PhD
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A Simple Mathematical Model for Wound Closure Evaluation
The incidence of ulcers associated to type 2 diabetes mellitus (T2DM) increases every year. We introduce and explore a new mathematical algorithm to evaluate wound-healing in foot ulcers associated to T2DM. Fifteen patients (nine women and six men), mean age of 70 ± 16 years were included. The evolution of their wounds followed-up for a period of 18–45 days. According to the Wagner grading system the ulcers were grade I (5 patients), grade II (9 patients), and grade III (1 patient). Clinically, the type of the ulcers was neuroischemic (12 patients) and neuropathic (3 patients). A new parameter is introduced, the “continuous linear healing rate” Dc that was more accurate with higher values and requires less quantifications than usual formulas to make a wound-healing projection.
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