Biosciences, Biotechnology Research Asia最新文献

Evaluation of Drug Utilization Pattern in Patients with Chronic Kidney Disease 慢性肾病患者药物利用模式的评价

Biosciences, Biotechnology Research Asia Pub Date : 2023-10-05 DOI: 10.13005/bbra/3157

Sangeetha B, Thangamani S

{"title":"Evaluation of Drug Utilization Pattern in Patients with Chronic Kidney Disease","authors":"Sangeetha B, Thangamani S","doi":"10.13005/bbra/3157","DOIUrl":"https://doi.org/10.13005/bbra/3157","url":null,"abstract":"Background: Chronic kidney disease is a major public health issue which requires complex pharmacotherapy. This study was aimed to evaluate drug utilization pattern in chronic kidney disease patients. Method: A prospective observational study was conducted at Nephrology department in Rajiv Gandhi Cooperative Multispecialty hospital, Palakkad for a period of 6 month from July 2022 to January 2023. Medications were assessed by using WHO prescribing indicator and classified in the basis of Anatomic Therapeutic Classification. Results: A total of 120 patients were examined. According to the ATC categorization, out of a total of 921 medicines, cardiovascular drugs were most frequently administered. The average number of drugs per prescription was 7.6%. 11.3% of those medications were prescribed by their generic names. 49.9% of drugs were prescribed on the accordance with essential medicine list. The patient prescribed with an injection was 46% and patients prescribed with antibiotic were 25.5%. Poly pharmacy was executed in 86% of patients. Antihypertensive drugs were most frequently recommended class of drugs followed by hematopoietic drugs and vitamin and minerals in therapeutic wise classification of drugs. Conclusion: Of all drugs prescribed, cardiovascular drugs were commonly prescribed and prevalence of poly pharmacy is high in patients due to co morbidities.","PeriodicalId":9032,"journal":{"name":"Biosciences, Biotechnology Research Asia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135546248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Seed Priming to Improve Tomato Productivity in Salinity Stressed Environments: A Review 盐胁迫环境下种子引种提高番茄产量的研究进展

Biosciences, Biotechnology Research Asia Pub Date : 2023-10-05 DOI: 10.13005/bbra/3133

Rupali Seth

{"title":"Seed Priming to Improve Tomato Productivity in Salinity Stressed Environments: A Review","authors":"Rupali Seth","doi":"10.13005/bbra/3133","DOIUrl":"https://doi.org/10.13005/bbra/3133","url":null,"abstract":"Tomato (Solanum lycopersicum L.) berries are in great demand across the globe for their nutritive and therapeutic properties. As agriculture land and fresh water resources are limited, the possibility of increasing the production of tomato is either by utilizing unproductive salt affected land for cultivation or unportable water high in salts for irrigation. Tomato is relatively susceptible to salinity during seed germination and seedling establishment phase. However, rapid and synchronized seed germination is essential for proper stand establishment in tomato for increasing its production in salinity stressed environments. Seed priming, a simple and lucrative approach for easing salt stress during the germination phase, is gaining popularity in tomato. Priming improves germination response and brings about certain biochemical changes that help primed tomato seeds to survive and grow under harsh conditions of salinity. This review discusses some of the seed priming methods such as hydropriming, osmopriming, solid matrix priming, hormonal priming, chemical priming, biopriming and physical priming that successfully mitigated the harmful effects of salt stress in tomatoes. Seed priming thus paves the way for utilization of saline land for growing tomato resulting in increased productivity and an improvement in tomato supply chain amidst rising demands.","PeriodicalId":9032,"journal":{"name":"Biosciences, Biotechnology Research Asia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135547130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

18S rRNA Approach for Identification of Chara L. Species 18S rRNA方法在菝葜属植物鉴定中的应用

Biosciences, Biotechnology Research Asia Pub Date : 2023-10-05 DOI: 10.13005/bbra/3154

Rekha Adimulam, P Sujathamma

引用次数: 0

A Recent Advancement Towards Herbal Biomass-Assisted Synthesis of Silver Nanoparticles 植物生物质辅助合成纳米银的研究进展

Biosciences, Biotechnology Research Asia Pub Date : 2023-10-05 DOI: 10.13005/bbra/3134

Ruchi Shivhare, Neelam Jain

{"title":"A Recent Advancement Towards Herbal Biomass-Assisted Synthesis of Silver Nanoparticles","authors":"Ruchi Shivhare, Neelam Jain","doi":"10.13005/bbra/3134","DOIUrl":"https://doi.org/10.13005/bbra/3134","url":null,"abstract":"Using plant extracts in metal nanoparticle production is a straightforward, practical, cost-effective, and ecologically benign alternative to the use of harmful chemicals. As a consequence, several approaches for the quick manufacture of silver nanoparticles that are acceptable to the environment and use aqueous extracts of plant materials including leaves, bark, and roots have been published recently. In this paper, recent advancements in the area of environmentally friendly manufacturing of silver nanoparticles (AgNPs) using diverse plant extracts are highlighted and expanded upon, along with the potential use of these materials as antibacterial agents. A thorough analysis of the potential effects of phytochemical concentrations in plant extracts, extraction temperatures, extraction solvents, reaction temperatures, reaction times, reaction pHs, and precursor concentrations. Furthermore provided are extensive details on the potential mechanism by which AgNPs have strong antibacterial action and induce cell death in pathogens by interacting with their cell walls. In addition, whereas chemical methods for shape-controlled synthesis are widely established, controlling the shape of biologically generated AgNPs has several advantageous effects on its activities.","PeriodicalId":9032,"journal":{"name":"Biosciences, Biotechnology Research Asia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135546991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neuroprotective Action of Polyphenols and Phenolic Compounds: An Overview 多酚和酚类化合物的神经保护作用综述

Biosciences, Biotechnology Research Asia Pub Date : 2023-10-05 DOI: 10.13005/bbra/3132

Shubham J. Khairnar, Ghanshyam B. Jadhav

引用次数: 0

Screening of Phytochemicals from Derris indica for Antimycobacterial Potential using Molecular Docking Analysis 利用分子对接分析筛选稻谷植物化学物质的抑菌潜力

Biosciences, Biotechnology Research Asia Pub Date : 2023-10-05 DOI: 10.13005/bbra/3142

Harsh Kashyap, Vanshika Makol, Manisha Khatri

{"title":"Screening of Phytochemicals from Derris indica for Antimycobacterial Potential using Molecular Docking Analysis","authors":"Harsh Kashyap, Vanshika Makol, Manisha Khatri","doi":"10.13005/bbra/3142","DOIUrl":"https://doi.org/10.13005/bbra/3142","url":null,"abstract":"Mycobacterium tuberculosis, responsible for causing tuberculosis (TB) in humans, continues to pose a significant worldwide threat, causing extensive fatalities as the most prominent bacterial disease and urgent attention is required to develop novel anti-TB drugs. Throughout the history of medicine, natural remedies have consistently held a vital position, offering valuable references for the development of new drugs. The present study aimed to screen phytoconstituents of Derris indica as inhibitors of protein kinase B, an enzyme critical for cell wall synthesis of Mtb using in silico approach. Molecular docking of phytochemical library of D. indica against PknB was carried out to explore binding interactions, alongwith in silico toxicity prediction of the phytoconstituents. The shortlisted phytoconstituents demonstrated favorable pharmacokinetic characteristics suitable for oral absorption and met the criteria set by Lipinski's rule of five, indicating their potential as drug candidates. Six compounds (Pongaflavanol, Kaempferol, Quercetin, Karanjin, Ovaliflavanone A and Pongaglabrone) demonstrated significant binding interactions with the minimum binding energy ranging from -9.71 kcal/mol to -8.68 kcal/mol as compared with conventional synthetic drugs. These selected phytoconstituents may serve as valuable starting points for the future advancement of effective and safe antimycobacterial drug.","PeriodicalId":9032,"journal":{"name":"Biosciences, Biotechnology Research Asia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135546105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Study on Ichthyofaunal Diversity and Fishing Gears Used in the Wetlands Areas Nearby Nimati Ghat, Jorhat, Assam 阿萨姆邦Jorhat Nimati Ghat湿地鱼类多样性及渔具使用研究

Biosciences, Biotechnology Research Asia Pub Date : 2023-10-05 DOI: 10.13005/bbra/3152

Gayotree Agni Borah, Somim Nasreen, Prasanna Kumar Dutta

引用次数: 0

Bioanalytical Studies on Fungal Pathogens Originating from Spoiled Alpan Banana (Musa Paradisiaca) 变质阿尔卑斯香蕉(Musa Paradisiaca)病原菌的生物分析研究

Biosciences, Biotechnology Research Asia Pub Date : 2023-10-05 DOI: 10.13005/bbra/3150

Amrendra Kumar singh, Prakash Chandra Gupta

{"title":"Bioanalytical Studies on Fungal Pathogens Originating from Spoiled Alpan Banana (Musa Paradisiaca)","authors":"Amrendra Kumar singh, Prakash Chandra Gupta","doi":"10.13005/bbra/3150","DOIUrl":"https://doi.org/10.13005/bbra/3150","url":null,"abstract":"Background: The entire Alpan banana plant can be utilized medicinally. Since the banana's rapid global expansion, several non-wood plant fibers have been used as substitutes for wood pulp in the manufacture of pulp, paper, and paper board. Currently, modest commercial pulping operations use a range of non-wood fibers, including bamboo, jute, straw, rice, and abaca. The increasing number of banana varieties is a result of the everyday developments that are being achieved in several fields. The Materials and Methods: The purpose of this current study is to check fungal pathogenicity in infected Alpan banana fruit, molecular characterization of the pathogenic species and evaluation of biochemical activities in banana fruit. The studied biochemical activities include protein content, ascorbic acid, total sugar and total phenolic compounds. Ascorbic acid oxidase (AAO) and Phenol Oxidase (PPO) are also studied in the selected banana variety. Result: The fungal pathogenicity assay showed incidence of Aspergillus species on Alpan banana fruit. A very high prevalence of Aspergillus flavus and Aspergillus fumigatus were observed in examined fruits. Species confirmation were based on molecular characterization method and its subsequent bioinformatic analysis. Proteins, total phenolic content and Keto acid were observed to be 223.01, 47.32 and 964.0 mg/g respectively whereas PPO and AAO showed 0.800 and 0.175 U/ml content in the fruit sample. Conclusion:The study concludes the prevalence of fungal infection in ripe bananas by Aspergillus species and changes observed at their biochemical constituents level post fungal infestation","PeriodicalId":9032,"journal":{"name":"Biosciences, Biotechnology Research Asia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135546850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cellobiose Dehydrogenase from Schizophyllum commune Bcc26414: Purification and Characterization 裂叶菌Bcc26414纤维素二糖脱氢酶的纯化及特性研究

Biosciences, Biotechnology Research Asia Pub Date : 2023-10-05 DOI: 10.13005/bbra/3141

Vinita Yadav, Sadhana Nighojkar

引用次数: 0

Identification and Assessment of Non-Genetic Factors Contributing to Nephrolithiasis (Kidney Stone) in the Jammu Region 查谟地区肾结石(肾结石)非遗传因素的鉴定和评估

Biosciences, Biotechnology Research Asia Pub Date : 2023-10-05 DOI: 10.13005/bbra/3140

Kanak Mahajan, Meenakshi Bhagat, Jessica Cherukuri, Rahul Gupta, Amrit Sudershan, Rakesh Kumar Panjaliya, Parvinder Kumar

引用次数: 0