Progress in nuclear energy. Series 6 Biological sciences最新文献

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Phytochemical screening of Solanum xanthocarpum and its xanthine oxidase inhibitory activity 黄原胶的植物化学筛选及其黄嘌呤氧化酶抑制活性
Progress in nuclear energy. Series 6 Biological sciences Pub Date : 2022-01-01 DOI: 10.55006/biolsciences.2022.2308
M. Imran, Haya Majid, Mohammed Ali, A. Qadir
{"title":"Phytochemical screening of Solanum xanthocarpum and its xanthine oxidase inhibitory activity","authors":"M. Imran, Haya Majid, Mohammed Ali, A. Qadir","doi":"10.55006/biolsciences.2022.2308","DOIUrl":"https://doi.org/10.55006/biolsciences.2022.2308","url":null,"abstract":"Pharmacological features and chemical compounds derived from Solanum xanthocarpum are often investigated. S. xanthocarpum has been widely used to treat a variety of ailments as traditional medicine. Different parts of the plant are being studied to find more new uses for the herb. Xanthine oxidase inhibition is important in many vascular, renal, and bone disorders as this super enzyme causes an increase in uric acid formation and oxidative stress. With this perspective and current literature, further studies are required to be conducted to highlight new features that may be derived from the plant. This study aimed to explore the fruits of Solanum xanthocarpum for their phytochemical constituents and their xanthine oxidase inhibitory activity. Fruits from S. xanthocarpum were identified and collected. We performed alcoholic extraction in the Soxhlet apparatus and fractionation using column chromatography. Furthermore, we analyzed phytochemical properties using fingerprinting chromatography, NMR (Nuclear magnetic resonance), Mass-spectrometry, Ultraviolet (UV), and infrared (IR) spectroscopy. The NMR spectrum revealed new chemical moieties which were validated using mass spectrometry. Later on, we conducted bioassays for xanthine oxidase Inhibitory activity on individual fractions. Three new chemical compounds were discovered (Eicosa -11, 14-dienoic acid, Docosa-7, 10, 13, 16, 19-pentanoic acid, and Glyceryl Tri Palmitoleate). These compounds were fatty acids in nature. Bioassay results obtained were positive and encouraging. Our study findings provide evidence of new chemical compounds that can be derived from Solanum xanthocarpum and can be used to treat renal diseases and gout by inhibiting excessive enzyme catalyzation of xanthine oxidase. The results suggest S. xanthocarpum as a possible candidate for a new therapeutic approach.","PeriodicalId":90302,"journal":{"name":"Progress in nuclear energy. Series 6 Biological sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70991417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Distribution of fission products in animals at Maralinga. 马拉林加动物体内裂变产物的分布。
D W BARNES, W J BUTTERFIELD
{"title":"Distribution of fission products in animals at Maralinga.","authors":"D W BARNES, W J BUTTERFIELD","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":90302,"journal":{"name":"Progress in nuclear energy. Series 6 Biological sciences","volume":"3 ","pages":"91-115"},"PeriodicalIF":0.0,"publicationDate":"1961-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32132406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radioactive isotopes in animal thyroids. 动物甲状腺中的放射性同位素。
P DUNN
{"title":"Radioactive isotopes in animal thyroids.","authors":"P DUNN","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":90302,"journal":{"name":"Progress in nuclear energy. Series 6 Biological sciences","volume":"3 ","pages":"116-25"},"PeriodicalIF":0.0,"publicationDate":"1961-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32130063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The distribution of radioactivity in rabbits following ingestion of fission products collected from atomic weapon clouds. 兔子摄取原子武器云收集的裂变产物后的放射性分布。
T E CARR, G E HARRISON, A SUTTON
{"title":"The distribution of radioactivity in rabbits following ingestion of fission products collected from atomic weapon clouds.","authors":"T E CARR, G E HARRISON, A SUTTON","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":90302,"journal":{"name":"Progress in nuclear energy. Series 6 Biological sciences","volume":"3 ","pages":"35-53"},"PeriodicalIF":0.0,"publicationDate":"1961-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32132411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interrelations of nucleic acid and protein syntheses in radiation-induced mutation induction in bacteria. 辐射诱导细菌突变过程中核酸和蛋白质合成的相互关系。
F L HAAS, C O DOUDNEY
{"title":"Interrelations of nucleic acid and protein syntheses in radiation-induced mutation induction in bacteria.","authors":"F L HAAS, C O DOUDNEY","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":90302,"journal":{"name":"Progress in nuclear energy. Series 6 Biological sciences","volume":"2 ","pages":"167-78"},"PeriodicalIF":0.0,"publicationDate":"1959-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32135232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fine structure of chromosomes in man and other metazoa and testicular recovery from x-rays in mammals. 人类和其他后生动物染色体的精细结构和哺乳动物睾丸x射线的恢复。
B R NEBEL
{"title":"Fine structure of chromosomes in man and other metazoa and testicular recovery from x-rays in mammals.","authors":"B R NEBEL","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":90302,"journal":{"name":"Progress in nuclear energy. Series 6 Biological sciences","volume":"2 ","pages":"404-10"},"PeriodicalIF":0.0,"publicationDate":"1959-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32131635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The influence of oxygen and peroxides on the response of mammalian cells and tissues to ionizing radiations. 氧和过氧化物对哺乳动物细胞和组织对电离辐射反应的影响。
L H GRAY, H B CHASE, E E DESCHNER, J W HUNT, O C SCOTT
{"title":"The influence of oxygen and peroxides on the response of mammalian cells and tissues to ionizing radiations.","authors":"L H GRAY, H B CHASE, E E DESCHNER, J W HUNT, O C SCOTT","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":90302,"journal":{"name":"Progress in nuclear energy. Series 6 Biological sciences","volume":"2 ","pages":"69-81"},"PeriodicalIF":0.0,"publicationDate":"1959-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32135226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antibody formation in x-irradiated rats protected with rat or rabbit hematopoietic cells. 用大鼠或兔造血细胞保护x射线照射大鼠的抗体形成。
M F LA VIA, E L SIMMONS, J D DENKO
{"title":"Antibody formation in x-irradiated rats protected with rat or rabbit hematopoietic cells.","authors":"M F LA VIA, E L SIMMONS, J D DENKO","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":90302,"journal":{"name":"Progress in nuclear energy. Series 6 Biological sciences","volume":"2 ","pages":"161-6"},"PeriodicalIF":0.0,"publicationDate":"1959-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32135259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors affecting the relative biological efficiencies of ionizing radiations. 影响电离辐射相对生物效率的因素。
K C BORA
{"title":"Factors affecting the relative biological efficiencies of ionizing radiations.","authors":"K C BORA","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":90302,"journal":{"name":"Progress in nuclear energy. Series 6 Biological sciences","volume":"2 ","pages":"278-99"},"PeriodicalIF":0.0,"publicationDate":"1959-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32137042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Some factors influencing radioresistance and tumor induction in plants. 影响植物辐射抗性和肿瘤诱导的一些因素。
A H SPARROW, L A SCHAIRER
{"title":"Some factors influencing radioresistance and tumor induction in plants.","authors":"A H SPARROW, L A SCHAIRER","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":90302,"journal":{"name":"Progress in nuclear energy. Series 6 Biological sciences","volume":"2 ","pages":"351-8"},"PeriodicalIF":0.0,"publicationDate":"1959-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32131660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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