Korean journal of audiology最新文献_第7页

Tuberculous otitis media with facial paralysis combined with labyrinthitis. 结核性中耳炎伴面瘫合并迷路炎。

Korean journal of audiology Pub Date : 2013-04-01 Epub Date: 2013-04-16 DOI: 10.7874/kja.2013.17.1.27

Gyu Ho Hwang, Jong Yoon Jung, Gunhwee Yum, June Choi

引用次数: 11

Compound Nevus Occurring Near External Auditory Canal: Successful Treatment by CO2 Laser Abrasion. 外耳道附近发生的复合痣:CO2激光磨耗成功治疗。

Korean journal of audiology Pub Date : 2013-04-01 Epub Date: 2013-04-16 DOI: 10.7874/kja.2013.17.1.30

Won-Serk Kim, Kye Hoon Park

引用次数: 4

Mechanisms and treatment of blast induced hearing loss. 爆炸致听力损失的机制和治疗。

Korean journal of audiology Pub Date : 2012-12-01 Epub Date: 2012-12-18 DOI: 10.7874/kja.2012.16.3.103

Chul-Hee Choi

{"title":"Mechanisms and treatment of blast induced hearing loss.","authors":"Chul-Hee Choi","doi":"10.7874/kja.2012.16.3.103","DOIUrl":"https://doi.org/10.7874/kja.2012.16.3.103","url":null,"abstract":"The main objective of this study is to provide an overview of the basic mechanisms of blast induced hearing loss and review pharmacological treatments or interventions that can reduce or inhibit blast induced hearing loss. The mechanisms of blast induced hearing loss have been studied in experimental animal models mimicking features of damage or injury seen in human. Blast induced hearing loss is characterized by perforation and rupture of the tympanic membrane, ossicular damage, basilar membrane damage, inner and outer hair cell loss, rupture of round window, changes in chemical components of cochlear fluid, vasospasm, ischemia, oxidative stress, excitotoxicity, hematoma, and hemorrhage in both animals and humans. These histopathological consequences of blast exposure can induce hearing loss, tinnitus, dizziness, and headache. The pharmacological approaches to block or inhibit some of the auditory pathological consequences caused by blast exposure have been developed with antioxidant drugs such as 2,4-disulfonyl α-phenyl tertiary butyl nitrone (HXY-059, now called HPN-07) and N-acetylcysteine (NAC). A combination of antioxidant drugs (HPN-07 and NAC) was administered to reduce blast induced cochlear damage and hearing loss. The combination of the antioxidant drugs can prevent or treat blast induced hearing loss by reducing damage to the mechanical and neural component of the auditory system. Although information of the underlying mechanisms and treatment of blast induced hearing loss are provided, further and deep research should be achieved due to the limited and controversial knowledge. ","PeriodicalId":90252,"journal":{"name":"Korean journal of audiology","volume":"16 3","pages":"103-7"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.7874/kja.2012.16.3.103","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32195550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 20

Time course of the suppression effect on transient evoked otoacoustic emissions by prolonged contralateral acoustic stimulation. 对侧长时间声刺激对瞬态诱发耳声发射抑制作用的时间过程。

Korean journal of audiology Pub Date : 2012-12-01 Epub Date: 2012-12-18 DOI: 10.7874/kja.2012.16.3.114

Hyun Woo Kang, Hyun Joon Shim, Seong Jun Song, Seong Hee Lee, Sang Won Yoon

{"title":"Time course of the suppression effect on transient evoked otoacoustic emissions by prolonged contralateral acoustic stimulation.","authors":"Hyun Woo Kang, Hyun Joon Shim, Seong Jun Song, Seong Hee Lee, Sang Won Yoon","doi":"10.7874/kja.2012.16.3.114","DOIUrl":"https://doi.org/10.7874/kja.2012.16.3.114","url":null,"abstract":"Background and objectives: Although the suppressive effect of the medial efferent acoustic reflex is well known, the time course of this effect over prolonged periods has yet to be fully evaluated. We assessed time-dependent change in the suppression of transient evoked otoacoustic emissions (TEOAEs) by the medial efferent acoustic reflex over a relatively long period.Subjects and methods: We measured TEOAEs in the right ear before contralateral acoustic stimulation (CAS), and then measured serial TEOAEs in the right ear at four intervals during a total of 16 minutes of continuous CAS, followed by three more recordings after termination of CAS.Results: TEOAE amplitudes were reduced with CAS during a certain period (from the immediate period to 10 minutes depending on frequency) and subsequently recovered. TEOAE suppression values in the mean amplitudes for overall frequency were 0.76 dB at the initial recording, 0.35 dB at 5 minutes, 0.44 dB at 10 minutes, and 0.33 dB at 15 minutes during CAS. The initial suppression value was significantly larger than other suppression values of 5, 10, and 15 minutes (p<0.05). In recordings obtained after CAS, TEOAE amplitude exceeded pre-acoustic amplitudes at 1 kHz, 1.5 kHz, and 2 kHz.Conclusions: The present results show the existence of the medial efferent acoustic reflex and demonstrate the time course that TEOAE suppressions present initially after CAS, showing fatigue over time. Overshooting of TEOAE was observed in recordings at several frequencies after termination of CAS.","PeriodicalId":90252,"journal":{"name":"Korean journal of audiology","volume":"16 3","pages":"114-9"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/df/c7/kja-16-114.PMC3936663.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32195552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Mupirocin ointment prevents early post-tympanostomy tube otorrhea: a preliminary study. 莫匹罗星软膏预防早期鼓室造瘘后耳漏:初步研究。

Korean journal of audiology Pub Date : 2012-12-01 Epub Date: 2012-12-18 DOI: 10.7874/kja.2012.16.3.130

Kye Hoon Park, Chi-Kyou Lee

{"title":"Mupirocin ointment prevents early post-tympanostomy tube otorrhea: a preliminary study.","authors":"Kye Hoon Park, Chi-Kyou Lee","doi":"10.7874/kja.2012.16.3.130","DOIUrl":"https://doi.org/10.7874/kja.2012.16.3.130","url":null,"abstract":"Background and objectives: The most common complication of tympanostomy tube (T-tube) insertion is the development of postoperative otorrhea. Post-tympanostomy tube otorrhea (PTTO) is defined as active drainage through an existing T-tube. Many surgeons routinely use topical antibiotics as prophylaxis against early PTTO. Mupirocin calcium ointment is a topical antimicrobial agent with broad-spectrum antimicrobial activity against many Gram-positive organisms. This study evaluated the clinical effectiveness of topical mupirocin ointment in reducing early PTTO.Subjects and methods: The study included 98 ears (67 patients, mean age 32.9 years) that had a T-tube inserted because of chronic middle ear effusion or atelectatic otitis media. A Paparella type-I polyethylene-tube coated with mupirocin was inserted through the tympanostomy. Patients were instructed not to use otic drops or any other medications. All patients were seen by day 14 postoperatively.Results: Early PTTO occurred in one case (1.5%). No early PTTO was seen with a middle ear effusion. Nineteen children were treated under general anesthesia; none developed early PTTO.Conclusions: Insertion of a T-tube coated with mupirocin ointment could be effective at preventing early PTTO.","PeriodicalId":90252,"journal":{"name":"Korean journal of audiology","volume":"16 3","pages":"130-3"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a5/fa/kja-16-130.PMC3936664.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32194966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A case of malignant small round cell tumor of temporal bone with facial paralysis. 颞骨恶性小圆细胞瘤伴面瘫1例。

Korean journal of audiology Pub Date : 2012-12-01 Epub Date: 2012-12-18 DOI: 10.7874/kja.2012.16.3.145

Jae-Hong Lee, Jae-Hyun Seo, Kyung-Ho Park, Beom Cho Jun

引用次数: 1

Comparative analysis of the expression of involucrin, filaggrin and cytokeratin 4, 10, 16 in cholesteatoma. 胆脂瘤组织中天青蛋白、聚丝蛋白及细胞角蛋白4,10,16表达的比较分析。

Korean journal of audiology Pub Date : 2012-12-01 Epub Date: 2012-12-18 DOI: 10.7874/kja.2012.16.3.124

Hyun Jung Min, Chul Won Park, Jin Hyeok Jeong, Seok Hyun Cho, Kyung Rae Kim, Seung Hwan Lee

{"title":"Comparative analysis of the expression of involucrin, filaggrin and cytokeratin 4, 10, 16 in cholesteatoma.","authors":"Hyun Jung Min, Chul Won Park, Jin Hyeok Jeong, Seok Hyun Cho, Kyung Rae Kim, Seung Hwan Lee","doi":"10.7874/kja.2012.16.3.124","DOIUrl":"https://doi.org/10.7874/kja.2012.16.3.124","url":null,"abstract":"Background and objectives: The aim of this study is to determine whether the hyperproliferative and hyperkeratotic characters of cholesteatoma are associated with differentiation of keratinocytes in cholesteatoma by examining the localization of marker proteins, such as involucrin, filaggrin, and cytokeratins.Materials and methods: Immunohistochemical study was carried out in 30 cholesteatoma tissues and 10 retroauricular skins to examine the expression of involucrin, filaggrin, cytokeratin 4, 10 and 16. The staining results were graded as negative, weakly positive (<10%), moderately positive (10-70%), and strongly positive (>70%).Results: Involucrin was strongly expressed in upper spinous, granular, and corneal layer of cholesteatoma. Filaggrin was strongly expressed in granular and corneal layer of cholesteatoma. Cytokeratin 4 was expressed in basal layer of retroauricular skin, but occasionally expressed in suprabasal layer of cholesteatoma. Cytokeratin 10 was homogenously expressed in all suprabasal layer of retroauricular skin, whereas pattern of shift to surface layer was showed in cholesteatoma. Cytokeratin 16 was moderately expressed at suprabasal layer in cholesteatoma.Conclusions: It can be suggested that early differentiation of suprabasal layer may lead to hyperdifferentiation and hyperkeratosis. Different expression of cytokeratins possibly indicates the altered differentiation of cholesteatoma.","PeriodicalId":90252,"journal":{"name":"Korean journal of audiology","volume":"16 3","pages":"124-9"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/66/10/kja-16-124.PMC3936667.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32194965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

A case with the bilateral narrow bony cochlear nerve canals associated with near normal hearing thresholds. 双侧骨性耳蜗神经管狭窄伴听力阈接近正常1例。

Korean journal of audiology Pub Date : 2012-12-01 Epub Date: 2012-12-18 DOI: 10.7874/kja.2012.16.3.141

Jae-Cheul Ahn, Shin-Hye Kim, Byung Yoon Choi

引用次数: 1

Role of nicotinic acetylcholine receptor on efferent inhibition in cochlear hair cell. 烟碱乙酰胆碱受体在耳蜗毛细胞传出抑制中的作用。

Korean journal of audiology Pub Date : 2012-12-01 Epub Date: 2012-12-18 DOI: 10.7874/kja.2012.16.3.108

Gi Jung Im

引用次数: 4

Cerebrospinal fluid otorrhea caused by arachnoid granulation. 蛛网膜肉芽造成脑脊液耳漏。

Korean journal of audiology Pub Date : 2012-12-01 Epub Date: 2012-12-18 DOI: 10.7874/kja.2012.16.3.152

Sang Woo Kim, Jeong Hwan Choi

引用次数: 4