Biological Communications最新文献_第3页

Prospects for biobanking in reproductive health: genetic aspects 生殖健康生物银行的前景:遗传方面

Biological Communications Pub Date : 2022-12-31 DOI: 10.21638/spbu03.2022.404

A. Glotov, Y. Nasykhova, N. Dvoynova, A. Mikhailova, O. Pachulia, Maria Danilova, Z. Tonyan, Y. Barbitoff, R. Illarionov, O. Bespalova, V. Baranov, I. Kogan

{"title":"Prospects for biobanking in reproductive health: genetic aspects","authors":"A. Glotov, Y. Nasykhova, N. Dvoynova, A. Mikhailova, O. Pachulia, Maria Danilova, Z. Tonyan, Y. Barbitoff, R. Illarionov, O. Bespalova, V. Baranov, I. Kogan","doi":"10.21638/spbu03.2022.404","DOIUrl":"https://doi.org/10.21638/spbu03.2022.404","url":null,"abstract":"Currently, one of the most promising areas of medicine is the development and implementation of new biomedical technologies in the field of human reproduction with the involvement of resources of biobanks and biocollections as well as modern genetic technologies. In this review, we considered the key dimensions of personalized medicine, such as biobanking and genomic medicine. We illustrated crucial aspects in the organization of human bioresource collections and the difficulties arising in the interaction of specialists in the field of biobanking. Problems in obtaining informed consent and collecting personal data are described. Furthermore, the need for creating and developing complex information systems for storing, processing, and analyzing data, creating genetic databases is emphasized. Foreign experience in consolidation of biobank data and the results of genomic studies is summarized. We also describe D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology’s experience in creating collections of human biomaterials (today it contains more than 60,000 samples, including samples of blood and its derivatives (plasma, serum, whole blood), urine samples, placental tissue, cell cultures, DNA, RNA, and others) and in quality management. The main results of genetic research are provided. Experience in these studies served as the basis for the creation of Biobank “Genofond” and the unique scientific facility “Human Reproductive Health”. The principle of creation of the collection, its purpose, and objectives for future research in the genetics of reproduction are described.","PeriodicalId":8998,"journal":{"name":"Biological Communications","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44575211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Biobanks as an important tool in modern translational oncology 生物库是现代转化肿瘤学研究的重要工具

Biological Communications Pub Date : 2022-12-31 DOI: 10.21638/spbu03.2022.405

Elena Petersen, Darya Chudakova, E. Shabalina, A. Shiryaev, N. Sukortseva, G. Zhemerikin, P. Karalkin, I. Reshetov

引用次数: 0

Scientific collections of the Zoological Institute of the Russian Academy of Sciences, Saint Petersburg 圣彼得堡俄罗斯科学院动物研究所的科学收藏

Biological Communications Pub Date : 2022-12-31 DOI: 10.21638/spbu03.2022.407

A. Abramov, L. Voyta, P. Kijashko

{"title":"Scientific collections of the Zoological Institute of the Russian Academy of Sciences, Saint Petersburg","authors":"A. Abramov, L. Voyta, P. Kijashko","doi":"10.21638/spbu03.2022.407","DOIUrl":"https://doi.org/10.21638/spbu03.2022.407","url":null,"abstract":"The Zoological Institute of the Russian Academy of Sciences in St Petersburg is one of the oldest biological research institutions in Russia, housing the largest zoological collections in the country, both in terms of their size (number of specimens) and global diversity. It is also one of the largest zoological depositories in the world, with over 60 million specimens in its stores. In total, the Zoological Institute holds about 260,000 animal species, about a quarter of the world’s known diversity. The type collection includes several tens of hundreds of primary types, which are very important as the essential foundation for zoological nomenclature. The digitisation of scientific collections now plays an important role in ensuring the standardised accumulation and use of various data sets, as well as quick access to stored information. The digitised scientific collections of the Zoological Institute are published online for the public access. To date they have accumulated 146,695 taxa records and over 13,000 high quality images of invertebrate and vertebrate specimens and their original data labels. The Zoological Institute is not only a depository of animal specimens important for biodiversity inventories and studies, but also a unique bank of genetic resources of extant/extinct animals which can be studied using modern genetic technologies.","PeriodicalId":8998,"journal":{"name":"Biological Communications","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44932384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Creation, working principles, development of applied and fundamental scientific activities of the Collection of Cell Cultures of Vertebrates 脊椎动物细胞培养物保藏中心的创建、工作原理、应用和基础科学活动的发展

Biological Communications Pub Date : 2022-12-31 DOI: 10.21638/spbu03.2022.406

G. Poljanskaya, D. Bobkov, A. Koltsova, A. Musorina, N. Mikhailova

引用次数: 0

Personalized medicine: the role of sequencing technologies in diagnostics, prediction and selection of treatment of monogenous and multifactorial diseases 个性化医学：测序技术在单因素和多因素疾病诊断、预测和治疗选择中的作用

Biological Communications Pub Date : 2022-12-31 DOI: 10.21638/spbu03.2022.403

O. Glotov, A. Chernov, Michael Fedyakov, V. Larionova, A. Zaretsky, M. Donnikov, A. Glotov

{"title":"Personalized medicine: the role of sequencing technologies in diagnostics, prediction and selection of treatment of monogenous and multifactorial diseases","authors":"O. Glotov, A. Chernov, Michael Fedyakov, V. Larionova, A. Zaretsky, M. Donnikov, A. Glotov","doi":"10.21638/spbu03.2022.403","DOIUrl":"https://doi.org/10.21638/spbu03.2022.403","url":null,"abstract":"The review highlights various methods for deciphering the nucleotide sequence (sequencing) of nucleic acids and their importance for the implementation of the three main principles of personalized medicine: prevention, predictability and personalization. The review, along with its own practical examples, considers three generations of sequencing technologies: 1) sequencing of cloned or amplified DNA fragments according to Sanger and its analogues; 2) massive parallel sequencing of DNA libraries with short reads (NGS); and 3) sequencing of single molecules of DNA and RNA with long reads. The methods of whole genome, whole exome, targeted, RNA sequencing and sequencing based on chromatin immunoprecipitation are also discussed. The advantages and limitations of the above methods for diagnosing monogenic and oncological diseases, as well as for identifying risk factors and predicting the course of socially significant multifactorial diseases are discussed. Using examples from clinical practice, algorithms for the application and selection of sequencing technologies are demonstrated. As a result of the use of sequencing technologies, it has now become possible to determine the molecular mechanism of the development of monogenic, orphan and multifactorial diseases, the knowledge of which is necessary for personalized patient therapy. In science, these technologies paved the way for international genome projects — the Human Genome Project, the HapMap, 1000 Genomes Project, the Personalized Genome Project, etc.","PeriodicalId":8998,"journal":{"name":"Biological Communications","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45591129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New ptyctodontid placoderm from the Famennian (Upper Devonian) of European Russia 俄国欧洲区法门纪(上泥盆世)新齿状齿板皮动物

Biological Communications Pub Date : 2022-12-31 DOI: 10.21638/spbu03.2022.401

A. Ivanov

引用次数: 0

Epixylic diversity in an old-growth boreal forest is influenced by dynamic substrate attributes 北方古老森林中的木糖学多样性受动态基质属性的影响

Biological Communications Pub Date : 2022-12-31 DOI: 10.21638/spbu03.2022.402

Helena Kushnevskaya, E. Borovichev, E. Shorohova

{"title":"Epixylic diversity in an old-growth boreal forest is influenced by dynamic substrate attributes","authors":"Helena Kushnevskaya, E. Borovichev, E. Shorohova","doi":"10.21638/spbu03.2022.402","DOIUrl":"https://doi.org/10.21638/spbu03.2022.402","url":null,"abstract":"Quantifying the factors influencing wood-inhabiting species in boreal forests is crucial for better understanding of their ecology and conservation needs. We estimated the influence of substrate attributes on epixylic diversity on logs of Picea abies, Betula pubescens, B. pendula, Populus tremula and Pinus sylvestris in a mixed European old-growth boreal forest with high substrate availability and continuity. The number of species of different taxonomic and substrate groups in respect of log attributes was estimated with generalized linear models. The composition of epixylic communities was analysed using non-metric multidimensional scaling with subsequent environmental fitting. Additionally, we calculated species interaction networks of log (tree) species and epixylic plants and lichens. Species richness per log decreased with the increasing height above the ground and increased with the increasing amount of accumulated litter. True epixylics were the most sensitive to a log position above the ground. Aspen and conifer logs harbored the highest richness of rare species of lichens and liverworts. Birch logs hosted mainly species with wide substrate amplitude. The whole epixylic community specialization index decreased in the order lichens, liverworts, mosses, vascular plants. Tree species identity and associated attributes (bark cover, pH etc.) as well as ‘dynamic’ attributes (accumulation of litter, wood decomposition and time since tree death) influenced the total species number, their taxonomic diversity, and the composition of epixylic communities. Our results indicate the importance of wood of various age and tree species for the conservation of epixylic diversity in boreal forests.","PeriodicalId":8998,"journal":{"name":"Biological Communications","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46080195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of “historical” DNA of museum samples resolve taxonomic, nomenclature and biogeography issues: case study of true lemmings 博物馆标本的“历史”DNA分析解决了分类学、命名学和生物地理学问题:真旅鼠的案例研究

Biological Communications Pub Date : 2022-12-31 DOI: 10.21638/spbu03.2022.408

N. Abramson, T. Petrova, N. Dokuchaev

{"title":"Analysis of “historical” DNA of museum samples resolve taxonomic, nomenclature and biogeography issues: case study of true lemmings","authors":"N. Abramson, T. Petrova, N. Dokuchaev","doi":"10.21638/spbu03.2022.408","DOIUrl":"https://doi.org/10.21638/spbu03.2022.408","url":null,"abstract":"Historical DNA of museum specimens is of paramount importance in elucidation of complex nomenclature issues and a priceless source of material gathered during preceding centuries in hardly accessible today sites. Here we report the results of genotyping type specimens of Lemmus obensis bungei Vinogradov, 1925 from the collection of the Zoological Institute RAS and specimens of lemmings from the upper streams of the Omolon River, identified as L. amurensis from the collection of the Institute of Systematics and Ecology of Animals, Siberian branch of RAS. The genetic profile of the type specimens in the first case was crucial for the nomenclatural solution as these specimens are from the point of the major evolutionary divergence on the Lena River. The results of the study convincingly showed that the lectotype belong to the eastern mitochondrial lineage of L. sibiricus. Therefore, if ever in the further studies it would be conclusively shown that this mitochondrial lineage may become a valid taxon of any rank, then names “novosibiricus”, “ognevi”, “portenkoi” will become younger synonyms of “bungei”. The new obtained sequences of the specimens from the Omolon prove initially wrong assignment and represent L. sibiricus eastern lineage.","PeriodicalId":8998,"journal":{"name":"Biological Communications","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48439138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Is recruitment of brown trout in a New Zealand river driven by parental spawning investment, density dependence, or environmental factors? 在新西兰河流中招募褐鳟是由亲代产卵投资、密度依赖还是环境因素驱动的？

Biological Communications Pub Date : 2022-10-10 DOI: 10.21638/spbu03.2022.306

P. Mikheev, C. Matthaei, T. Ingram, Matt G. Jarvis, G. Closs

{"title":"Is recruitment of brown trout in a New Zealand river driven by parental spawning investment, density dependence, or environmental factors?","authors":"P. Mikheev, C. Matthaei, T. Ingram, Matt G. Jarvis, G. Closs","doi":"10.21638/spbu03.2022.306","DOIUrl":"https://doi.org/10.21638/spbu03.2022.306","url":null,"abstract":"This study addresses the primary factors driving young-of-the-year (YoY) brown trout Salmo trutta abundance and population dynamics through the Austral summer in an important spawning tributary of a large New Zealand river. We measured the key traits and spawning investment of spawners; YoY density and movement; and environmental characteristics important for juvenile trout. In comparison to their native European range, we found high rates of pre-spawning mortality, low density of deposited eggs and reduced spawning efficiency of adult brown trout. Parental spawning investment did not affect spring juvenile trout distribution, a result likely related to a mismatch between YoY abundance and densities of eggs deposited by adults at the sampled locations. Spatial differences in seasonal dynamics of YoY density were likely related to the diversity of environmental conditions affecting habitat suitability for post-larval brown trout along the stream. Significant correlations between juvenile trout loss rate and both YoY density and downstream migration were observed only for the lowland stream segments, which had the highest spawning investment from diadromous adults, indicating the importance of these locations for recruitment. This study highlights knowledge gaps in species-environment interactions and the reproductive ecology of brown trout in New Zealand.","PeriodicalId":8998,"journal":{"name":"Biological Communications","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47208611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New perspectives on treatment of gastrointestinal diseases: therapeutic potential of mesenchymal stromal cells 间充质间质细胞治疗胃肠道疾病的新视角

Biological Communications Pub Date : 2022-10-10 DOI: 10.21638/spbu03.2022.307

O. Payushina, D. Tsomartova, Yelizaveta Chereshneva, M. Ivanova, N. Pashina, Elina Tsomartova, S. Kuznetsov

引用次数: 0