{"title":"Acquired and Congenital Abnormalities of the Pediatric Globe and Optic Nerve","authors":"A. Bhatt","doi":"10.1055/s-0036-1592426","DOIUrl":"https://doi.org/10.1055/s-0036-1592426","url":null,"abstract":"Abstract Abnormalities of the pediatric globe and optic nerve present with different clinical features than adults. While many of these lesions are benign, most have a significant impact on vision, and therefore, the radiologist can play a key role in patient care. This article will review the radiologic features of retinoblastoma, the most common pediatric orbital tumor, as well as other congenital abnormalities such as persistent hyperplastic primary vitreous, Coats disease, and retinopathy of prematurity. Abnormalities of globe development, such as coloboma and vascular lesions, will also be discussed, as these should prompt imaging of the entire neuroaxis due to association with systemic syndromes. Tumors of the optic nerve can also unmask an underlying syndrome, the most common being an optic nerve glioma occurring in the setting of neurofibromatosis type I.","PeriodicalId":89989,"journal":{"name":"Journal of pediatric neuroradiology","volume":"26 1","pages":"196 - 206"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73227210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pediatric Head and Neck Imaging","authors":"P. Kalina","doi":"10.1055/S-0036-1592424","DOIUrl":"https://doi.org/10.1055/S-0036-1592424","url":null,"abstract":"","PeriodicalId":89989,"journal":{"name":"Journal of pediatric neuroradiology","volume":"61 1","pages":"111 - 111"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88812131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Increasing Incidence and Imaging in Pediatric Head and Neck Cancer and Role of the Human Papilloma Virus and Epstein–Barr Virus","authors":"C. Kirsch, G. Dellacerra","doi":"10.1055/s-0036-1593402","DOIUrl":"https://doi.org/10.1055/s-0036-1593402","url":null,"abstract":"Abstract Over the past few decades, the incidence of head and neck squamous cell carcinomas in the pediatric population and tumors associated with oncogenic human papilloma virus (HPV) has continued to increase. Previously, head and neck cancers in young patients were considered rare and—only in patients with genetic risk factors, with clinicians unaware of these neoplasms—occurring with greater frequency in younger patients, and often associated with HPV infection. This article reviews the viral oncogenic properties of HPV and Epstein–Barr virus, what the biomarker p16 represents, and the salient clinical and radiographic features of these tumors. Clinical awareness of these features is important to identify these tumors and initiate appropriate therapeutic treatment and to avoid any delay in diagnosis.","PeriodicalId":89989,"journal":{"name":"Journal of pediatric neuroradiology","volume":"58 1","pages":"221 - 228"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81557347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vascular Anomalies of the Head and Neck: Diagnosis, Imaging, and Treatment","authors":"T. Beydoun, D. Aria, J. Curran, R. Towbin","doi":"10.1055/s-0036-1593422","DOIUrl":"https://doi.org/10.1055/s-0036-1593422","url":null,"abstract":"Abstract Vascular anomalies are congenital errors in vascular developments frequently involving the head and neck. Imaging often plays a pivotal role in the diagnosis requiring familiarity by the interpreting radiologist in order to best guide management. Multidisciplinary teams are essential in managing this group of pathologies. In a community setting, the radiologist may be the first encounter wherein the patient has the best chance of being appropriately referred to the dedicated team of specialists. Divided into malformations and tumors, we review their presentation with imaging correlation, natural history, and discussion of current treatment strategies focusing on the more common subcategories. Taking into consideration the physical and psychosocial effects of these diseases, swift diagnosis and appropriate treatment significantly improves quality of care and prognosis.","PeriodicalId":89989,"journal":{"name":"Journal of pediatric neuroradiology","volume":"19 1","pages":"137 - 149"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86018887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fetal Magnetic Resonance Imaging of Head and Neck Anomalies","authors":"Mai‐Lan Ho, C. Glastonbury, O. Glenn","doi":"10.1055/s-0036-1593423","DOIUrl":"https://doi.org/10.1055/s-0036-1593423","url":null,"abstract":"Abstract Fetal head and neck (HN) anomalies represent complex diagnostic and management challenges, often requiring serial imaging and a multidisciplinary team approach. In this article, we will review the prenatal magnetic resonance imaging diagnosis of HN malformations, with ultrasound and postnatal imaging correlation. Key topics to be discussed include craniofacial abnormalities, posterior fossa malformations, neural tube defects, cervicofacial masses, and airway anomalies.","PeriodicalId":89989,"journal":{"name":"Journal of pediatric neuroradiology","volume":"31 1","pages":"112 - 136"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89390387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Congenital Head and Neck Lesions","authors":"I. Meesa, S. Mukherji","doi":"10.1055/s-0036-1593419","DOIUrl":"https://doi.org/10.1055/s-0036-1593419","url":null,"abstract":"Abstract Various congenital head and neck lesions can present in the pediatric population. In this article, we will discuss some of the more common lesions encountered in the pediatric population including thyroglossal duct anomalies, dermoid cysts, branchial cleft anomalies, vascular and lymphatic malformations. Since they are encountered frequently, it is important for the radiologists to be aware of some of the common lesions and their imaging features.","PeriodicalId":89989,"journal":{"name":"Journal of pediatric neuroradiology","volume":"38 1","pages":"185 - 195"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81103805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Imaging Review of Common Space-Occupying Lesions of the Pediatric Head and Neck","authors":"G. Dellacerra, Alan A Johnson","doi":"10.1055/s-0036-1593424","DOIUrl":"https://doi.org/10.1055/s-0036-1593424","url":null,"abstract":"Abstract Head and neck masses continue to be a common indication for neuroradiological evaluation of pediatric patients. Etiologies include inflammatory, congenital, benign neoplastic, and malignant neoplastic lesions. The incidence of childhood head and neck malignancy is increasing, and therefore should always be included in the differential diagnosis of a pediatric patient presenting with a space-occupying lesion of the head or neck. Many factors can aid in an accurate diagnosis, including age of the patient, location of the mass, and imaging features. This article will review several benign and malignant pediatric head and neck neoplasms, as well as congenital lesions, and focus on their imaging features.","PeriodicalId":89989,"journal":{"name":"Journal of pediatric neuroradiology","volume":"24 1","pages":"207 - 220"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78539067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Drevelegas, D. Chourmouzi, Manos Constantinides, K. Drevelegas
{"title":"Posterior Fossa Tumors","authors":"A. Drevelegas, D. Chourmouzi, Manos Constantinides, K. Drevelegas","doi":"10.1055/s-0036-1592425","DOIUrl":"https://doi.org/10.1055/s-0036-1592425","url":null,"abstract":"Abstract In this article, we review the most common posterior fossa pediatric neoplasms. We describe the computed tomography and magnetic resonance imaging (MRI) findings used in the initial evaluation of a pediatric brain tumors. We also discuss the advanced MRI techniques which provide information about the physiology of the tumors and play an important role in the differential diagnosis as well as in the preoperative evaluation of different tumor types.","PeriodicalId":89989,"journal":{"name":"Journal of pediatric neuroradiology","volume":"15 1","pages":"089 - 110"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80470796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Common Pediatric Central Nervous System Tumors: Histology and Molecular Biology","authors":"A. Goussia","doi":"10.1055/s-0036-1592352","DOIUrl":"https://doi.org/10.1055/s-0036-1592352","url":null,"abstract":"Abstract Central nervous system tumors represent the most common solid tumors of childhood. The heterogeneous group of gliomas comprises the majority of pediatric tumors while embryonal neoplasms represent the second most frequent group of tumors. Histopathological diagnosis according to World Health Organization is of great importance for defining prognosis and choosing the appropriate treatment. Recently, attempts have been made to correlate specific genomic alterations to clinical outcome. Adding molecular information to classic histology seems to improve diagnostic accuracy and risk stratification of patients.","PeriodicalId":89989,"journal":{"name":"Journal of pediatric neuroradiology","volume":"23 1","pages":"049 - 053"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87162630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Aspects of Pediatric Brain Tumors","authors":"E. Vargìami, D. Zafeiriou","doi":"10.1055/s-0036-1592353","DOIUrl":"https://doi.org/10.1055/s-0036-1592353","url":null,"abstract":"Abstract Brain tumors are the most common solid tumor entity in children and constitute 15 to 20% of all childhood malignancies. All health care professionals seeing children should be able to identify signs and symptoms arising from a central nervous system (CNS) tumor and refer or investigate appropriately. Despite advances in neuroimaging, the timely diagnosis of CNS tumors remains difficult. It is well-known that any delay in diagnosis leads to further tumor progress and thus worsens the outcome and the risk of additional brain damage, thus making an early diagnosis crucial. This article reviews the presenting clinical features that characterize children with brain tumors.","PeriodicalId":89989,"journal":{"name":"Journal of pediatric neuroradiology","volume":"47 1","pages":"046 - 048"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85387425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}