{"title":"Myelination: General Principles","authors":"C. Parazzini, G. Conte, F. Triulzi","doi":"10.1007/978-3-662-46258-4_2-1","DOIUrl":"https://doi.org/10.1007/978-3-662-46258-4_2-1","url":null,"abstract":"","PeriodicalId":89989,"journal":{"name":"Journal of pediatric neuroradiology","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83083045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Can Apparent Diffusion Coefficient Values Predict Time of Onset in Term Neonates with Hypoxic–Ischemic Injury?","authors":"M. Eissawy, M. Higazi, S. Maher","doi":"10.1055/s-0036-1597689","DOIUrl":"https://doi.org/10.1055/s-0036-1597689","url":null,"abstract":"Abstract Background Hypoxic–ischemic injury (HII) is a significant cause of neonatal morbidity and mortality. It had been postulated that apparent diffusion coefficient (ADC) abnormalities in term neonatal HII generally peak at 3 to 5 days after birth and subsequently “pseudonormalize” by the end of the first week. Thus, ADC values may provide a clue for timing of HII. Objective In this study, we sought to assess whether ADC values can always predict time of hypoxic ischemic insult. Methodology We prospectively analyzed 34 full-term neonates with suspected HII by diffusion-weighted (DW) magnetic resonance imaging (MRI) within 14 days after birth. DW images (DWIs) were assessed for areas of restricted diffusion at different locations that could be encountered in HII. ADC maps were generated and ADC values were calculated. Spearman correlation coefficient and receiver operating characteristic (ROC) curve analyses were performed. Results The mean age of neonates at time of MRI was 8 (±4) days (range: 2–14 days). No significant correlation detected between ADC values and age of neonates at time of imaging (p = 0.183; R2 = 0.06). ROC curve analysis showed that ADC values could not discriminate between neonates who were imaged early (≤7 days) or later (p = 0.391; area under the curve = 0.633). Conclusion ADC values may not be capable to accurately predict time of onset in term neonates with HII. ADC values should always be interpreted in combination with both conventional and DWIs, and each case should be individualized instead of generalization.","PeriodicalId":89989,"journal":{"name":"Journal of pediatric neuroradiology","volume":"55 1","pages":"242 - 247"},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81544887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Leon-Wyss, B. Foerster, Cynthia Rosario, J. Toribio, Herwin Speckter, J. Oviedo, P. Stoeter
{"title":"Influence of Oxygen Saturation and Age on Relaxation Time of Gray and White Matter and Diffusion Tensor Imaging Parameters in Children with Cardiac Malformations","authors":"J. Leon-Wyss, B. Foerster, Cynthia Rosario, J. Toribio, Herwin Speckter, J. Oviedo, P. Stoeter","doi":"10.1055/s-0036-1597687","DOIUrl":"https://doi.org/10.1055/s-0036-1597687","url":null,"abstract":"Abstract The aim of this article is to investigate the influence of reduced arterial oxygenation on cerebral gray and white matter T2* time and parameters of diffusion tensor imaging (DTI) in children with cardiac malformations. In 23 patients examined by magnetic resonance imaging (3T), parameters were correlated to oxygen saturation and age (regression analysis). Reduced oxygen saturation correlated significantly to gray matter T2* time (p ≤ 0.01), whereas fractional anisotropy, mean diffusivity, and radial diffusivity correlated to age (p ≤ 0.005) but not to oxygenation. To conclude, gray matter T2* time might be used as a surrogate parameter to estimate oxygenation, and oxygenation does not influence the evaluation of DTI parameters.","PeriodicalId":89989,"journal":{"name":"Journal of pediatric neuroradiology","volume":"144 1","pages":"248 - 252"},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76223941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Iniencephalic Fetus Detected on Fetal Magnetic Resonance Imaging","authors":"T. Onal, Guven Onur Afacan, Y. Anık, G. Akansel","doi":"10.1055/s-0036-1597659","DOIUrl":"https://doi.org/10.1055/s-0036-1597659","url":null,"abstract":"Abstract Fetal iniencephaly is an uncommon neural tube anomaly characterized by fixed retroflexion of the head, an occipital defect, and cervicothoracic rachischisis. Polyhydramnios and elevated levels of α-fetoprotein are present in most cases. Fetal iniencephaly can be detected on antenatal ultrasonography. If undiagnosed prenatally, it may result in a difficult delivery as well a multitude of postnatal problems for both the patient and the family. Early antenatal diagnosis is therefore important. We present a case of iniencephaly detected on ultrasonography and fetal magnetic resonance imaging.","PeriodicalId":89989,"journal":{"name":"Journal of pediatric neuroradiology","volume":"138 1","pages":"253 - 255"},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88713306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Two-Digit Number Processing during Childhood: A Mental Rotation Task?","authors":"S. Kreis, W. Reith, C. Krick","doi":"10.1055/s-0036-1597672","DOIUrl":"https://doi.org/10.1055/s-0036-1597672","url":null,"abstract":"Abstract The association between numerical and spatial thinking manifests itself throughout various cognitive observations, concerning arithmetic problem solving as well as simple number recognition tasks. The spatial component in numerical thinking is assumed to represent the semantic processing pathway, for example, the mental representation of numerical magnitude. There is an interconnection of semantic, linguistic, and visual/symbolic pathways, which is thought to be stronger in adults than in children. During childhood, the semantic pathway is supposed to play a major part in numerical processing. In this study, we conducted a functional magnetic resonance imaging paradigm combining a mental rotation task with a number processing task. The behavioral data showed the highest error rate for two-digit numbers (not for three-digit numbers). In regard to two-digit numbers, we also found the strongest neuronal activation overlap for number processing and mental rotation in the left intraparietal sulcus. This pattern suggests that the mental inversion of digits in native German speakers might be a spatial function related to mental rotation. In terms of overcoming opposed informational input for symbolic and linguistic representation and therefore impeded informational extraction the spatial processing pathway might play a major role. To conclude, spatial training could be an effective educational approach, supporting the interconnection of numerical processing pathways.","PeriodicalId":89989,"journal":{"name":"Journal of pediatric neuroradiology","volume":"76 1","pages":"235 - 241"},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86475148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christopher Storey, C. Notarianni, A. Nanda, Hugo H. Cuellar-Saenz
{"title":"Spontaneous Occlusion of a Vein of Galen Malformation: A Case Report and Proposed Mechanism","authors":"Christopher Storey, C. Notarianni, A. Nanda, Hugo H. Cuellar-Saenz","doi":"10.1055/s-0036-1597688","DOIUrl":"https://doi.org/10.1055/s-0036-1597688","url":null,"abstract":"Abstract A vein of Galen malformation (VGM) is a rare condition of the pediatric population. Our patient was diagnosed with VGM on intrauterine ultrasound. At birth, she was noted to have multiple congenital heart defects but no signs of congestive heart failure, and intervention was delayed. Our patient presented at 4 months of age with worsening hydrocephalus due to the enlargement of the VGM. A ventricular peritoneal shunt was placed. At 26 months of age, our patient was taken for embolization of the VGM. Cerebral angiography showed no VGM. We present that changes in hemodynamics after shunt placement lead to the thrombosis of the VGM.","PeriodicalId":89989,"journal":{"name":"Journal of pediatric neuroradiology","volume":"52 1","pages":"256 - 262"},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72676618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Imaging of the Pediatric Temporal Bone Abnormalities","authors":"M. Gencturk, H. Tore, D. Nascene, C. Truwit","doi":"10.1055/s-0036-1593420","DOIUrl":"https://doi.org/10.1055/s-0036-1593420","url":null,"abstract":"Abstract Abnormalities of the temporal bone in children may be associated with important morbidity. Congenital, undiagnosed hearing loss occurring can impair normal cognitive development and should therefore be diagnosed and treated as soon as possible. The most common indication of temporal bone imaging in childhood is congenital hearing loss. Both high-resolution computed tomography and magnetic resonance imaging are helpful in diagnosis of a variety of congenital, inflammatory, traumatic, and neoplastic disorder.","PeriodicalId":89989,"journal":{"name":"Journal of pediatric neuroradiology","volume":"91 1","pages":"164 - 184"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80499632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Craniosynostosis Syndromes: Genetics to Imaging","authors":"Mai‐Lan Ho, S. Mardini, N. Wetjen","doi":"10.1055/s-0036-1593421","DOIUrl":"https://doi.org/10.1055/s-0036-1593421","url":null,"abstract":"Abstract Craniosynostosis is seen in 1 of every 2,000 births, with associated craniofacial deformities that produce significant anatomic and functional impairment. In isolated craniosynostosis, the classic clinical appearances and surgical approaches are well established. However, syndromic craniosynostosis presents with compound anatomic malformations and multisystem involvement, greatly complicating diagnosis and therapy. In such cases, imaging and genomic analysis can assist greatly in preoperative diagnosis and follow-up. This article will review the current literature on radiologic manifestations and genetic etiologies of major craniosynostosis syndromes.","PeriodicalId":89989,"journal":{"name":"Journal of pediatric neuroradiology","volume":"6 1","pages":"150 - 163"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80309647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pediatric Head and Neck Radiology: Selected Cases","authors":"J. Guerin, P. Kalina","doi":"10.1055/s-0036-1593546","DOIUrl":"https://doi.org/10.1055/s-0036-1593546","url":null,"abstract":"Abstract The aim of the this article is to give brief overview of a few classic pediatric head and neck disease processes, including congenital malformations, neoplasms, and inflammatory sequelae. Radiologists should be familiar with the imaging characteristics, associated clinical scenario and differential diagnoses of these entities to ensure proper management.","PeriodicalId":89989,"journal":{"name":"Journal of pediatric neuroradiology","volume":"140 1","pages":"229 - 234"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77721993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}