BioInorganic Reaction Mechanisms最新文献

{"title":"Kinetics and Mechanism of Oxidation of β-Alanine by a Ag(III) Complex","authors":"S. Huo, C. Song, J. Shan, S. Shen, Hanwen Sun","doi":"10.1515/IRM.2007.6.3.231","DOIUrl":"https://doi.org/10.1515/IRM.2007.6.3.231","url":null,"abstract":"","PeriodicalId":8996,"journal":{"name":"BioInorganic Reaction Mechanisms","volume":"97 1","pages":"231 - 238"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83500653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kinetic and Mechanistic Studies of Uncatalysed Substitution of Coordinated Cyanide in Hexacyanoferrate(II) by Phenylhydrazine","authors":"R. Naik, R. Tiwari, P. Singh, A. Verma","doi":"10.1515/IRM.2007.6.3.217","DOIUrl":"https://doi.org/10.1515/IRM.2007.6.3.217","url":null,"abstract":"The kinetics of uncatalyzed reaction between hexacyanoferrate(II) and 2,2'-Bipyridine (further designated as Bipy) has been followed spectrophotometrically by monitoring the increase in absorbance at 400 nm, the λmax of cherry red complex, [Fe(CN)4Bipy] 2– as a function of pH, Ionic strength, temperature and concentration of reactants. In this reaction, the coordinated cyanide ion in hexacyanoferrate(II) get replaced by incoming ligand Bipy under the following specified reaction conditions. Temperature = 30+0.1 o C, pH = 3.8+0.02 and I = 0.10 M (KNO3). The uncatalyzed reaction between [Fe(CN)6] 4– and Bipy is very slow. The reaction follows first order dependence each in [Fe(CN)6] 4– and [Bipy]. It was found that the initial rate varies linearly with increasing concentration of hexacyanoferrate(II), keeping other variables fixed at an optimum value. The initial rate is also found to increase in the beginning with increasing concentration of [Bipy] up to [Bipy] < 1.5×10 -4 M, passes through a maximum and then finally falls. The effect of pH, ionic strength on initial rate have also been studied and explained. The activation parameters for reaction have been evaluated. A most plausible mechanistic scheme has been proposed based on the experimental observations.","PeriodicalId":8996,"journal":{"name":"BioInorganic Reaction Mechanisms","volume":"96 1","pages":"217 - 224"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78764747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanism of Interaction of DNA Bases with Pd(II)-azoimidazoles: The Cytosine Case","authors":"S. Saha, Tapas Majumdar, Ambikesh Mahapatra","doi":"10.1515/IRM.2006.6.1.19","DOIUrl":"https://doi.org/10.1515/IRM.2006.6.1.19","url":null,"abstract":"Cytosine is responsible for maintaining cytosineguanine triple hydrogen bonded bond pairing during coding information transfer of progeny [1,2]. There is a long-standing interest to explore the interaction of carcinogenic agents and anticancer drugs with DNA [3-12]. Inorganic Reaction Mechanisims, Vol. 6, pp. 19-29 © 2006 Old City Publishing, Inc. Reprints available directly from the publisher Published by license under the OCP Science imprint, Photocopying permitted by license only a member of the Old City Publishing Group.","PeriodicalId":8996,"journal":{"name":"BioInorganic Reaction Mechanisms","volume":"224 1","pages":"19 - 29"},"PeriodicalIF":0.0,"publicationDate":"2006-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89167593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kinetics and Mechanism of Oxidation of Iminodiacetatochromium(III) by Periodate","authors":"H. Ewais, Faris D. Al-Otaibi, A. ABDEL-KHALEK,","doi":"10.1515/IRM.2006.6.1.39","DOIUrl":"https://doi.org/10.1515/IRM.2006.6.1.39","url":null,"abstract":"The oxidation of chromium from the trivalent to hexavalent states is an important environmental process because of the high mobility and toxicity of chromium(VI) [1]. Periodate oxidations have been reported to play an important role in biological determinants [2, 3]. They are used to degrade carbohydrate determinants in proteins without altering protein or lipid epitopes [2, 3]. The oxidation of hexacyanoferrate(II) by periodate has been investigated previously in weakly alkaline and neutral phosphate buffer solution and the kinetic were observed to be simple [4]. The oxidation kinetics of hexacyanoferrate(II) by periodate in acetate buffer was also studied [5]. It was reported that the mechanism of oxidation greatly differed on going from alkaline to acidic solution, whereas in acidic solutions the reaction rate was not only independent of periodate, but also inhibited by its increasing concentration. Symons [6] reported that the oxidation of iron(II) by periodate proceeds via a series of one electron-transfer steps. The polymerization of added acrylonitrile was taken as a criterion for the formation Inorganic Reaction Mechanisims, Vol. 6, pp.39-47 © 2006 Old City Publishing, Inc. Reprints available directly from the publisher Published by license under the OCP Science imprint, Photocopying permitted by license only a member of the Old City Publishing Group.","PeriodicalId":8996,"journal":{"name":"BioInorganic Reaction Mechanisms","volume":"112 1","pages":"39 - 47"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85860606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Micellar Effects on the Reactions of Chromium(VI) Oxidation of Lactic Acid and Malic Acid in the Presence and Absence of Picolinic Acid in Aqueous Acid Media","authors":"B. Saha, Monirul Islam, A. Das","doi":"10.1515/IRM.2006.6.2.141","DOIUrl":"https://doi.org/10.1515/IRM.2006.6.2.141","url":null,"abstract":"Among the different chelating agents like 1,10phenanthroline, 2,2/-bipyridyl, ethylenediaminetetraacetic acid and oxalic acid acting as catalysts [1,2] in Cr(VI) oxidation of different substrates, the catalytic ability [2,3,4] of picolinic acid (PA) is unique and of considerable interest. Picolinic acid (PA) is never cooxInorganic Reaction Mechanisims, Vol. 6, pp. 141-149 © 2006 Old City Publishing, Inc. Reprints available directly from the publisher Published by license under the OCP Science imprint, Photocopying permitted by license only a member of the Old City Publishing Group.","PeriodicalId":8996,"journal":{"name":"BioInorganic Reaction Mechanisms","volume":"14 1","pages":"141 - 149"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87605946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interaction Between Pd(RaaiR/)Cl2 and HQ: Reaction Dynamics and Mechanism (RaaiR/ = 1-alkyl-2-(arylazo)imidazole; HQ = 8-Quinolinol)","authors":"S. Saha, Ambikesh Mahapatra","doi":"10.1515/IRM.2006.6.1.71","DOIUrl":"https://doi.org/10.1515/IRM.2006.6.1.71","url":null,"abstract":"","PeriodicalId":8996,"journal":{"name":"BioInorganic Reaction Mechanisms","volume":"110 1","pages":"71 - 80"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76106197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kinetics and Mechanism of Oxidation of Sodium Glycollate by Dihydroxyditelluratoargentate(III) in Alkaline Medium","authors":"S. Huo, J. Shan, S. Li, S. Shen, Hanwen Sun","doi":"10.1515/IRM.2006.6.2.113","DOIUrl":"https://doi.org/10.1515/IRM.2006.6.2.113","url":null,"abstract":"The study of the highest accessible oxidation state of transition metals has intrigued many researchers. Transition metals in a higher oxidation state generally can be stabilized by chelation with suitable polydentate ligands. Metal complexes such as diperiodatoargentate(III) [1], ditelluratorargentate(III) [2], ditelluratocuprate(III) [3], and diperiodatonickelate(IV) [4] are good oxidants in a medium with an appropriate pH value. The use of complexes as good oxidizing agents in analytical chemistry has been well reported [5,6]. The oxidation of a number of organic compounds and metals in lower oxidation states by Ag(III) has also been performed, but no further information on the kinetics is available. In this Inorganic Reaction Mechanisims, Vol. 6, pp. 113-118 © 2006 Old City Publishing, Inc. Reprints available directly from the publisher Published by license under the OCP Science imprint, Photocopying permitted by license only a member of the Old City Publishing Group.","PeriodicalId":8996,"journal":{"name":"BioInorganic Reaction Mechanisms","volume":"3 1","pages":"113 - 118"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80257377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inner-sphere Oxidation of a Ternary Complex Involving Iminodiacetatochromium(III) and DL-Aspartic acid by Periodate","authors":"A. ABDEL-KHALEK,, H. Ewais, Faris D. AL-OTAIBIF,","doi":"10.1515/IRM.2006.6.1.31","DOIUrl":"https://doi.org/10.1515/IRM.2006.6.1.31","url":null,"abstract":"The oxidation of chromium from the trivalent to hexavalent states is an important environmental process because of the high mobility and toxicity of chromium(VI) [1]. Chromium(VI) compounds are well known to be potent toxic and carcinogenic agents. Because chromium(VI) is easily taken up by cells and is subsequently reduced to the trivalent form, the formation of chromium(III) or other Inorganic Reaction Mechanisims, Vol. 6, pp. 31-38 © 2006 Old City Publishing, Inc. Reprints available directly from the publisher Published by license under the OCP Science imprint, Photocopying permitted by license only a member of the Old City Publishing Group.","PeriodicalId":8996,"journal":{"name":"BioInorganic Reaction Mechanisms","volume":"154 6 1","pages":"31 - 38"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83143089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Inclusion of (Ferrocenylmethyl)trimethylammonium Complexes in Para-Sulfonated Calixarenes on the Kinetics of Their Electron Transfer Reactions","authors":"J. A. Imonigie, D. Macartney","doi":"10.1515/IRM.2006.6.2.161","DOIUrl":"https://doi.org/10.1515/IRM.2006.6.2.161","url":null,"abstract":"The guest-host inclusion of transition metal complexes in macrocyclic receptors can have a pronounced effect on the kinetics of their electron transfer1-12 reactions in solution. In addition to rendering an included complex less reactive or nonreactive by means of inhibiting their access to the other reactant(s) in the reaction process, the inclusion can also change other properties, such as their reduction potential,13 which will in turn affect the kinetics of their electron transfer reactions. The effects of guest-host interactions on the kinetics of electron-exchange and electron transfer reactions of transition metal complexes have been studied with cyclic host molecules such as the crown ethers,1-4 cyclodextrins,6-12 and calixarenes.5 The kinetic behaviour of the included transit ion metal Inorganic Reaction Mechanisims, Vol. 6, pp. 161-168 © 2006 Old City Publishing, Inc. Reprints available directly from the publisher Published by license under the OCP Science imprint, Photocopying permitted by license only a member of the Old City Publishing Group.","PeriodicalId":8996,"journal":{"name":"BioInorganic Reaction Mechanisms","volume":"16 1","pages":"161 - 168"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80061533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mono- and Dinuclear Copper(II) Complexes of Pendant-Arm Macrocyclic Polyamines: Synthesis, Characterization and Investigation as Hydrolytic Cleavage Agents for DNA","authors":"Nichola Mccann, G. D. Iuliis, G. Lawrance, M. Maeder, K. Schrader, P. Moore","doi":"10.1515/IRM.2006.6.2.91","DOIUrl":"https://doi.org/10.1515/IRM.2006.6.2.91","url":null,"abstract":"Based on the 10-methyl-1,4,8,12-tetraazacyclopentadecane-10-amine (1) parent, macrocycles 10-benzylamine-10-methyl-1,4,8,12-tetraazacyclopentadecane (2), 10-(2'-pyridinylmethanamino) -10-methyl-1,4,8,1 2-tetraazacyclopentadecane (3) and 5-(hydroxymethyl)-5'-(10 ''-methyl-1 '',4 '',8 '',12 ''-tetraazacyclopentadecane-10 ''-amino)-(2,2'-dipyridine) (4), as well as the p-xylene-linked dinucleating macrocycle 1,4-bis( 10'-methyl-1',4',8',12'-tetraazacyclopentacecane-10'-aminomethyl)benzene (5) and its o-xylene analogue (6), have been synthesized as free ligands and or copper(II) complexes and characterized spectroscopically. Cyclic voltammetry of the Cu(II) complexes of 2 - 6 are also reported, with involvement of the pendant groups in complexation influencing voltammetric behaviour. Potentionnetric titrations of 1, 2, 5 and 6 and their Cu(II) complexes yielded pK(a) values. Both dimers 5 and 6, as well as their mononuclear close analogues 1 and 2, have proven to be inefficient as hydrolytic cleavage agents for DNA, as was also the case for mononuclear Cu(II) complexes of N-4-macrocycles with a range of N-pendant groups based on the 3,7,11,17-tetraazabicyclo[11.3.1]heptadeca-1(17),13,15-triene framework (7). Mononuclear triazamacrocyclic Cu(II) complexes show greater activity. Of other dinuclear systems examined, dicopper(II) complexes of the relatively rigid compartment ligands 3,13-dimethyl-3,13-dinitro-1,5,11,15-tetraazacycloeicosane-8,18-diol and -dithiol are also inactive. Whereas the 1:1 Cu(II):L complexes of cyclam and its N,N',N '',N '''-tetrakis(methylbenzyl) substituted analogue are inactive, the tetrakis(2-methylpyridine)-substituted analogue as a 2:1 Cu(II):L species mu-hydroxy {tetrakis(2'-methylpyridine)-1,4,8,11-tetraazacyclotetradecane} dicopper(II) is very efficient as a cleavage agent for plasmid DNA, with both single and double strand cleavage steps observed with rate constants (at pH 7.6, 37 degrees C, 0.8 mM complex, 0.12 mg/mL plasmid) of 1.2x10(-4) and 3.5x10(-6) s(-1) respectively. This is attributed to the capacity for concerted binding to the phosphodiester unit and nucleophilic attack by the coordinated hydroxide molecule that is activated by bridging between the two metal centres.","PeriodicalId":8996,"journal":{"name":"BioInorganic Reaction Mechanisms","volume":"24 1","pages":"112 - 91"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77774432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}