Journal of blood transfusion最新文献_第2页

Association between Perioperative Blood Transfusions and Clinical Outcomes in Patients Undergoing Bladder Cancer Surgery: A Systematic Review and Meta-Analysis Study 膀胱癌手术患者围手术期输血与临床结局的关系:一项系统回顾和荟萃分析研究

Journal of blood transfusion Pub Date : 2016-01-31 DOI: 10.1155/2016/9876394

J. Cata, J. Lasala, G. Pratt, Lei Feng, J. Shah

{"title":"Association between Perioperative Blood Transfusions and Clinical Outcomes in Patients Undergoing Bladder Cancer Surgery: A Systematic Review and Meta-Analysis Study","authors":"J. Cata, J. Lasala, G. Pratt, Lei Feng, J. Shah","doi":"10.1155/2016/9876394","DOIUrl":"https://doi.org/10.1155/2016/9876394","url":null,"abstract":"Background. Perioperative blood transfusions are associated with poor survival in patients with solid tumors including bladder cancer. Objective. To investigate the impact of perioperative blood transfusions on oncological outcomes after radical cystectomy. Design. Systematic review and meta-analysis. Setting and Participants. Adult patients who underwent radical cystectomy for bladder cancer. Intervention. Packed red blood cells transfusion during or after radical cystectomy for bladder cancer. Outcome Measurements and Statistical Analysis. Recurrence-free survival (RFS), cancer-specific survival (CSS), and overall survival (OS). We calculated the pooled hazard ratio (HR) estimates and 95% confidence intervals by random and fixed effects models. Results and Limitation. Eight, seven, and five studies were included in the OS, CSS, and RFS analysis, respectively. Blood transfusions were associated with 27%, 29%, and 12% reduction in OS, CSS, and RFS, respectively. A sensitivity analysis supported the association. This study has several limitations; however the main problem is that it included only retrospective studies. Conclusions. Perioperative BT may be associated with reduced RFS, CSS, and OS in patients undergoing RC for BC. A randomized controlled study is needed to determine the causality between the administration of blood transfusions and bladder cancer recurrence.","PeriodicalId":89964,"journal":{"name":"Journal of blood transfusion","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85104341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 50

Quality Assessment of Established and Emerging Blood Components for Transfusion. 输血用已建立和新出现血液成分的质量评估。

Journal of blood transfusion Pub Date : 2016-01-01 Epub Date: 2016-12-14 DOI: 10.1155/2016/4860284

Jason P Acker, Denese C Marks, William P Sheffield

{"title":"Quality Assessment of Established and Emerging Blood Components for Transfusion.","authors":"Jason P Acker, Denese C Marks, William P Sheffield","doi":"10.1155/2016/4860284","DOIUrl":"https://doi.org/10.1155/2016/4860284","url":null,"abstract":"Blood is donated either as whole blood, with subsequent component processing, or through the use of apheresis devices that extract one or more components and return the rest of the donation to the donor. Blood component therapy supplanted whole blood transfusion in industrialized countries in the middle of the twentieth century and remains the standard of care for the majority of patients receiving a transfusion. Traditionally, blood has been processed into three main blood products: red blood cell concentrates; platelet concentrates; and transfusable plasma. Ensuring that these products are of high quality and that they deliver their intended benefits to patients throughout their shelf-life is a complex task. Further complexity has been added with the development of products stored under nonstandard conditions or subjected to additional manufacturing steps (e.g., cryopreserved platelets, irradiated red cells, and lyophilized plasma). Here we review established and emerging methodologies for assessing blood product quality and address controversies and uncertainties in this thriving and active field of investigation.","PeriodicalId":89964,"journal":{"name":"Journal of blood transfusion","volume":"2016 ","pages":"4860284"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2016/4860284","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71435124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 62

Motivating Factors and Potential Deterrents to Blood Donation in High School Aged Blood Donors. 高中学龄献血者献血的激励因素及潜在阻碍因素。

Journal of blood transfusion Pub Date : 2016-01-01 Epub Date: 2016-05-15 DOI: 10.1155/2016/8624230

Rachel Finck, Alyssa Ziman, Matthew Hoffman, Michelle Phan-Tang, Shan Yuan

{"title":"Motivating Factors and Potential Deterrents to Blood Donation in High School Aged Blood Donors.","authors":"Rachel Finck, Alyssa Ziman, Matthew Hoffman, Michelle Phan-Tang, Shan Yuan","doi":"10.1155/2016/8624230","DOIUrl":"https://doi.org/10.1155/2016/8624230","url":null,"abstract":"Background. To ensure an adequate supply of blood, collection centers must design campaigns that successfully recruit and maintain an active donor pool. Understanding factors that motivate and deter individuals from donating may help centers develop targeted recruitment campaigns. These factors among high school aged blood donors have not yet been fully investigated. Study Design and Methods. A voluntary, anonymous survey was administered to student donors at high school mobile blood drives. The survey instrument asked the students to rate several potential motivating factors in their importance in the decision to donate blood and several potential deterring factors in their future decision whether or not to donate blood again. The survey also asked the students to rate the desirability of several potential incentives. Results. Motivating factors that reflected prosocial, empathetic, and altruistic thoughts and beliefs were rated highly by students. Pain from phlebotomy was most commonly chosen as potential deterrent. Movie tickets and cookies/snacks at the drive were rated as the most attractive incentives. Conclusion. High school aged blood donors are similar to other donor groups in their expressed motives for donating blood. This group may be unique in the factors that deter them from donating and in their preferences for different incentives. ","PeriodicalId":89964,"journal":{"name":"Journal of blood transfusion","volume":"2016 ","pages":"8624230"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2016/8624230","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34572419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 27

Epidemiology of Transfusion Transmitted Infection among Patients with β-Thalassaemia Major in Pakistan. 巴基斯坦重型β-地贫患者输血传播感染的流行病学。

Journal of blood transfusion Pub Date : 2016-01-01 Epub Date: 2016-07-31 DOI: 10.1155/2016/8135649

Rizwan Ahmed Kiani, Muhammad Anwar, Usman Waheed, Muhammad Javaid Asad, Saleem Abbasi, Hasan Abbas Zaheer

{"title":"Epidemiology of Transfusion Transmitted Infection among Patients with β-Thalassaemia Major in Pakistan.","authors":"Rizwan Ahmed Kiani, Muhammad Anwar, Usman Waheed, Muhammad Javaid Asad, Saleem Abbasi, Hasan Abbas Zaheer","doi":"10.1155/2016/8135649","DOIUrl":"10.1155/2016/8135649","url":null,"abstract":"Introduction. Transfusion Transmitted Infections (TTIs) continue to be a major risk in transfusions in many parts of the world. The transfusion-dependent β-thalassaemia patients are particularly at risk of acquiring TTIs. The current study was undertaken to estimate the prevalence of TTIs in transfusion-dependent β-thalassaemia patients. Material and Methods. A cross-sectional study of 1253 multitransfused thalassaemia major patients was conducted in five different centres of Islamabad, Rawalpindi, and Karachi. The study subjects were screened for HIV, HCV, and HBV. The screening was performed at two centres: Department of Pathology, Shaheed Zulfiqar Ali Bhutto (SZAB) Medical University, and Blood Transfusion Services, Jinnah Postgraduate Medical Centre, from July to December 2015. The confirmatory screening was performed by Chemiluminescent Immunoassay (CLIA). Results. Out of the 1253 multiple transfused patients, 317 (25.3%) were infected with TTIs. HCV was positive in 273 cases (21.7%), HBV in 38 cases (3.0%), and HIV in 6 cases (0.5%). Conclusion. HCV was the leading TTI in multitransfused thalassaemia major patients in the study. Presence of HIV in thalassaemia patients is a recent disturbing development in Pakistan. Improved regulation of blood banks including use of internationally or nationally evaluated kits will bring down the incidence of TTIs in transfusion-dependent β-thalassaemia patients. More stringent behavioral and serological pretransfusion screening of blood for TTIs must be implemented in blood banks. ","PeriodicalId":89964,"journal":{"name":"Journal of blood transfusion","volume":"2016 ","pages":"8135649"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983372/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34389310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Knowledge, Attitude, and Practice of Adult Population towards Blood Donation in Gondar Town, Northwest Ethiopia: A Community Based Cross-Sectional Study. 埃塞俄比亚西北部贡达尔镇成人献血的知识、态度和实践:一项基于社区的横断面研究。

Journal of blood transfusion Pub Date : 2016-01-01 Epub Date: 2016-07-19 DOI: 10.1155/2016/7949862

Mulugeta Melku, Betelihem Terefe, Fikir Asrie, Bamlaku Enawgaw, Tadele Melak, Yakob Gebregziabher Tsegay, Mohamedamin Areba, Elias Shiferaw

{"title":"Knowledge, Attitude, and Practice of Adult Population towards Blood Donation in Gondar Town, Northwest Ethiopia: A Community Based Cross-Sectional Study.","authors":"Mulugeta Melku, Betelihem Terefe, Fikir Asrie, Bamlaku Enawgaw, Tadele Melak, Yakob Gebregziabher Tsegay, Mohamedamin Areba, Elias Shiferaw","doi":"10.1155/2016/7949862","DOIUrl":"https://doi.org/10.1155/2016/7949862","url":null,"abstract":"Background. Though World Health Organization recommends 100% voluntary blood donation, the percentage of blood collected from voluntary blood donors and the average annual blood collection rate are extremely low in Ethiopia. The role of adults is crucial to meet the demand of safe blood. Thus, this study aimed to assess knowledge, attitude, and practice of adult population towards blood donation in Gondar town, Northwest Ethiopia. Method. A community based cross-sectional study was conducted among 768 adults. Multistage sampling technique together with simple random and systematic random sampling technique was employed. Bivariate and multivariate logistic regression analysis and bivariate correlation analysis were done. Result. About 436 (56.8%), 630 (82%), and 141 (18.4%) study participants had adequate knowledge, good attitude, and experience of blood donation, respectively. Secondary and higher educational statuses were significantly associated with adequate knowledge towards blood donation. Participants who were protestant by religion were more likely to have good attitude towards blood donation. Age, self-perceived health status, and religion were significantly associated with blood donation practice. Conclusion. Knowledge and attitude towards blood donation are high. However, the level of practice is low. District and national blood banks and transfusion agency should design strategies that promote and motivate the communities to donate blood. ","PeriodicalId":89964,"journal":{"name":"Journal of blood transfusion","volume":"2016 ","pages":"7949862"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2016/7949862","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34750912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 44

Low Dose Perioperative Intravenous Tranexamic Acid in Patients Undergoing Total Knee Arthroplasty: A Double-Blind Randomized Placebo Controlled Clinical Trial 全膝关节置换术患者围手术期静脉注射低剂量氨甲环酸:一项双盲随机安慰剂对照临床试验

Journal of blood transfusion Pub Date : 2015-12-06 DOI: 10.1155/2015/948304

M. Motififard, M. Tahririan, M. Saneie, S. Badiei, Amin Nemati

{"title":"Low Dose Perioperative Intravenous Tranexamic Acid in Patients Undergoing Total Knee Arthroplasty: A Double-Blind Randomized Placebo Controlled Clinical Trial","authors":"M. Motififard, M. Tahririan, M. Saneie, S. Badiei, Amin Nemati","doi":"10.1155/2015/948304","DOIUrl":"https://doi.org/10.1155/2015/948304","url":null,"abstract":"Background and Objectives. The null hypothesis of this study was that TA has no effect on postsurgical bleeding in patients undergoing TKA. Methods. This study was a double-blind randomized trial. In the first group (T) patients received 500 mg of intravenous Tranexamic acid (TA) twice (once preoperatively and once 3 hours postoperatively) and in the second group (P) they received slow infusion of normal saline as placebo. The primary outcome of the study was the level of Hb 48 hours after surgery. Results. Hb levels 48 hours after surgery as the primary outcome were 10.92 ± 0.97 and 10.23 ± 0.98 (g/dL) in groups T and P, respectively, and the difference was statistically significant (P = 0.001). Statistically significant differences were also observed in Hb levels 6 and 24 hours after surgery, the drain output 48 hours after surgery, and the number of units of packed cells transfused between study groups (P < 0.05). There was no significant difference in duration of hospitalization between the study groups (P = n.s.). Conclusions. The low dose perioperative intravenous TA significantly reduces blood loss, requirement for blood transfusion, and drain output in patients undergoing TKA. However, duration of hospitalization did not change significantly.","PeriodicalId":89964,"journal":{"name":"Journal of blood transfusion","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85151048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Assessment of Vascular Endothelial Growth Factor in Fresh versus Frozen Platelet Rich Plasma. 新鲜富血小板血浆与冷冻富血小板血浆中血管内皮生长因子的比较。

Journal of blood transfusion Pub Date : 2015-01-01 Epub Date: 2015-08-02 DOI: 10.1155/2015/706903

Nada Hosny, Fikry Goubran, Basma BadrEldin Hasan, Noha Kamel

{"title":"Assessment of Vascular Endothelial Growth Factor in Fresh versus Frozen Platelet Rich Plasma.","authors":"Nada Hosny, Fikry Goubran, Basma BadrEldin Hasan, Noha Kamel","doi":"10.1155/2015/706903","DOIUrl":"https://doi.org/10.1155/2015/706903","url":null,"abstract":"Platelet rich plasma (PRP) is hemoconcentration with platelets concentration above baseline values and high concentration of many growth factors. The aim of this study was to assess freezing effect on vascular endothelial growth factor (VEGF) release from PRP using two different activation methods to simplify its use in different clinical applications. PRP was prepared using two-centrifugation steps method from 12 qualified blood donors. VEGF concentrations were measured in fresh PRP and after freezing/thawing for one and three weeks with two methods of activation using (i) calcium gluconate and (ii) calcium gluconate and thrombin. Platelets count was significantly increased compared to baseline whole blood values in all fresh and frozen PRP samples (p value was <0.05). No significant difference was found between VEGF concentrations after activating fresh and frozen-thawed PRP samples for one and three weeks by calcium alone or calcium with thrombin, and also no significant difference was found when freezing period was extended from one to three weeks. Our results showed that platelets count does not correlate with variable levels of VEGF. PRP could be prepared once and preserved frozen for at least three weeks for the next treatment sessions and activation with thrombin addition to calcium will not augment the growth factor release. ","PeriodicalId":89964,"journal":{"name":"Journal of blood transfusion","volume":"2015 ","pages":"706903"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2015/706903","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33946448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16

Motivational Differences between Whole Blood and Apheresis Donors in Quebec, Canada: A Questionnaire-Based Survey in a Voluntary Nonremunerated Context. 加拿大魁北克省全血献血者和单采献血者的动机差异:一项基于自愿无偿背景下的问卷调查。

Journal of blood transfusion Pub Date : 2015-01-01 Epub Date: 2015-07-29 DOI: 10.1155/2015/568259

Johanne Charbonneau, Marie-Soleil Cloutier, Élianne Carrier

{"title":"Motivational Differences between Whole Blood and Apheresis Donors in Quebec, Canada: A Questionnaire-Based Survey in a Voluntary Nonremunerated Context.","authors":"Johanne Charbonneau, Marie-Soleil Cloutier, Élianne Carrier","doi":"10.1155/2015/568259","DOIUrl":"https://doi.org/10.1155/2015/568259","url":null,"abstract":"Background. Finding ways to recruit apheresis donors is crucial. The aim of this study was to provide a quantitative analysis of the motivations of regular plasma/platelets donors (PPDs) in comparison with those of regular whole blood donors (WBDs), in a voluntary and nonremunerated context. Study Design and Methods. Motives to donate blood and demographic characteristics were collected through questionnaires completed by 795 WBDs and 473 PPDs. Chi-square tests were completed to determine which motivations stand out across the two blood donor groups. Results. The motivator selected by the highest percentage was \"my blood can save lives.\" Comparison of WBDs and PPDs showed that 12 out of 23 items were statistically significantly different from one group to another. Conclusion. The belief that helping others is in their nature is more prevalent among PPDs. In this sense, their profile is unique. Four other motivators distinguish this group from the WBDs: \"I think there is a strong need for blood products,\" \"it gives me a sense of pride,\" \"I like to have goals,\" and \"I receive telephone reminders.\" These motivators point to the role the ongoing support provided by blood collection agencies (BCAs) plays with PPDs. ","PeriodicalId":89964,"journal":{"name":"Journal of blood transfusion","volume":"2015 ","pages":"568259"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2015/568259","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34007599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Blood transfusion, serum ferritin, and iron in hemodialysis patients in Africa. 非洲血液透析患者输血、血清铁蛋白和铁。

Journal of blood transfusion Pub Date : 2015-01-01 Epub Date: 2015-01-11 DOI: 10.1155/2015/720389

Leonard Kouegnigan Rerambiah, Laurence Essola Rerambiah, Armel Mbourou Etomba, Rose Marlène Mouguiama, Phanie Brunelle Issanga, Axel Sydney Biyoghe, Batchelili Batchilili, Sylvestre Akone Assembe, Joel Fleury Djoba Siawaya

{"title":"Blood transfusion, serum ferritin, and iron in hemodialysis patients in Africa.","authors":"Leonard Kouegnigan Rerambiah, Laurence Essola Rerambiah, Armel Mbourou Etomba, Rose Marlène Mouguiama, Phanie Brunelle Issanga, Axel Sydney Biyoghe, Batchelili Batchilili, Sylvestre Akone Assembe, Joel Fleury Djoba Siawaya","doi":"10.1155/2015/720389","DOIUrl":"https://doi.org/10.1155/2015/720389","url":null,"abstract":"Background and Objectives. There is no data analyzing the outcome of blood transfusions and oral iron therapy in patients with kidneys failure in sub-Saharan Africa. The present study aimed to fill that gap and assess the value of ferritin in the diagnosis of iron overload and deficiency. Design. From January to February 2012, we prospectively studied 85 hemodialysis patients (78% of males and 22% of females aged 20 to 79 years) attending the Gabonese National Hemodialysis Centre. Results. Correlation studies showed (a) a strong positive linear relationship between the number of blood transfusions and high serum ferritin in hemodialysis patient (Spearman r : 0.74; P value: 0.0001); (b) a weak association between the number of blood transfusions and serum iron concentrations (Spearman r : 0.32; P value: 0.04); (c) a weak association between serum ferritin and serum iron (Spearman r : 0.32; P value: 0.003). Also, the strength of agreement beyond chance between the levels of ferritin and iron in the serum was poor (κ = 0.14). The prevalence of iron overload was 10.6%, whereas the prevalence of iron deficiency was 2.3%, comparing (1) patients with a maximum of one transfusion not on iron therapy; (2) patients with a maximum of one transfusion on iron therapy; (3) polytransfused patients not on iron therapy; and (4) polytransfused patients on oral iron therapy. The “Kruskal-Wallis test” showed that ferritin levels varied significantly between the groups (P value: 0.0001). Conclusion. Serum ferritin is not reliable as a marker of iron overload. For patients undergoing regular transfusion we recommend routine serum ferritin measurement and yearly measurement of LIC.","PeriodicalId":89964,"journal":{"name":"Journal of blood transfusion","volume":"2015 ","pages":"720389"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2015/720389","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33383532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Infiltration of Autologous Growth Factors in Chronic Tendinopathies. 自体生长因子在慢性肌腱病变中的浸润。

Journal of blood transfusion Pub Date : 2015-01-01 Epub Date: 2015-06-15 DOI: 10.1155/2015/924380

Antonio Crescibene, Marcello Napolitano, Raffaella Sbano, Enrico Costabile, Hesham Almolla

{"title":"Infiltration of Autologous Growth Factors in Chronic Tendinopathies.","authors":"Antonio Crescibene, Marcello Napolitano, Raffaella Sbano, Enrico Costabile, Hesham Almolla","doi":"10.1155/2015/924380","DOIUrl":"https://doi.org/10.1155/2015/924380","url":null,"abstract":"Achilles tendinopathy and patellar tendinopathy are among the most frequent diagnoses in sports medicine. Therapeutic treatment of the disease is difficult, particularly in chronic cases. In literature, several studies suggest the employment of Platelet-Rich Plasma as a therapeutic alternative in tendinopathies. The choice of employing this method is based on the activity of growth factors contained in platelets which activate, amplify, and optimize the healing process. We selected 14 patients affected by Achilles tendinopathy and 7 patients affected by patellar tendinopathy, with a two-year final follow-up. These patients underwent a cycle of three tendinous infiltrations, after clinical and instrumental evaluation carried out by means of specific questionnaires and repeated ultrasound scans. Ultrasound scans of 18 patients showed signs of reduction in insertional irregularities. The result is confirmed by complete functional recovery of the patients, with painful symptomatology disappearing. The patients showed a clear pain reduction, along with an enhanced VISA score after the 24-month follow-up, equal to 84.2 points on a scale of 0 to 100. In conclusion, the present study provides evidence to suggest that PRP infiltration is a valid option to patients with chronic tendinopathy who did not benefit from other treatments. ","PeriodicalId":89964,"journal":{"name":"Journal of blood transfusion","volume":"2015 ","pages":"924380"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2015/924380","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34005722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15