ISRN AIDS最新文献_第4页

Prevalence and Factors Associated with Vitamin D Deficiency and Hyperparathyroidism in HIV-Infected Patients Treated in Barcelona. 在巴塞罗那接受治疗的hiv感染患者中维生素D缺乏和甲状旁腺功能亢进的患病率和相关因素

ISRN AIDS Pub Date : 2012-07-12 eCollection Date: 2012-01-01 DOI: 10.5402/2012/485307

Elisabet Lerma, M Ema Molas, M Milagro Montero, Ana Guelar, Alicia González, Judith Villar, Adolf Diez, Hernando Knobel

{"title":"Prevalence and Factors Associated with Vitamin D Deficiency and Hyperparathyroidism in HIV-Infected Patients Treated in Barcelona.","authors":"Elisabet Lerma, M Ema Molas, M Milagro Montero, Ana Guelar, Alicia González, Judith Villar, Adolf Diez, Hernando Knobel","doi":"10.5402/2012/485307","DOIUrl":"https://doi.org/10.5402/2012/485307","url":null,"abstract":"Vitamin D deficiency is an important problem in patients with chronic conditions including those with human immunodeficiency virus (HIV) infection. The aim of this cross-sectional study was to identify the prevalence and factors associated with vitamin D deficiency and hyperparathyroidism in HIV patients attended in Barcelona. Cholecalciferol (25OH vitamin D3) and PTH levels were measured. Vitamin D insufficiency was defined as 25(OH) D < 20 ng/mL and deficiency as <12 ng/mL. Hyperparathyroidism was defined as PTH levels >65 pg/mL. Cases with chronic kidney failure, liver disease, treatments or conditions potentially affecting bone metabolism were excluded. Among the 566 patients included, 56.4% were exposed to tenofovir. Vitamin D insufficiency was found in 71.2% and 39.6% of those had deficiency. PTH was measured in 228 subjects, and 86 of them (37.7%) showed high levels. Adjusted predictors of vitamin D deficiency were nonwhite race and psychiatric comorbidity, while lipoatrophy was a protective factor. Independent risk factors of hyperparathyroidism were vitamin D < 12 ng/mL (OR: 2.14, CI 95%: 1.19-3.82, P: 0.01) and tenofovir exposure (OR: 3.55, CI 95%: 1.62-7.7, P: 0.002). High prevalence of vitamin deficiency and hyperparathyroidism was found in an area with high annual solar exposure. ","PeriodicalId":89950,"journal":{"name":"ISRN AIDS","volume":"2012 ","pages":"485307"},"PeriodicalIF":0.0,"publicationDate":"2012-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767361/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31747010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Study of Depression and Its Associated Factors among Women Living with HIV/AIDS in Coastal South India. 印度南部沿海地区艾滋病毒/艾滋病妇女抑郁及其相关因素研究

ISRN AIDS Pub Date : 2012-06-21 eCollection Date: 2012-01-01 DOI: 10.5402/2012/684972

B Unnikrishnan, Vinita Jagannath, John T Ramapuram, B Achappa, D Madi

{"title":"Study of Depression and Its Associated Factors among Women Living with HIV/AIDS in Coastal South India.","authors":"B Unnikrishnan, Vinita Jagannath, John T Ramapuram, B Achappa, D Madi","doi":"10.5402/2012/684972","DOIUrl":"https://doi.org/10.5402/2012/684972","url":null,"abstract":"Background. Depression is one of the most prevalent psychiatric diagnoses seen in HIV-positive individuals. Women with HIV are about four times more likely to be depressed than those who are not infected. Aims. To assess the sociodemographic and clinical correlates of depression among women living with HIV/AIDS. Setting and Design. One public and one private hospital in Mangalore, Coastal South India, and cross-sectional design. Methods and Materials. Study constituted of 137 HIV-positive women, depression was assessed using BDI (Beck Depression Inventory), and social support was assessed using Lubben Social Network Scale. Statistical Analysis. All analysis was conducted using SPSS version 11.5. Chi-square test with P value less than 0.05 was taken as statistically significant. Results. Among 137 HIV-positive women, 51.1% were depressed. Around 16% were having moderate to high risk for isolation. Depression was statistically significant in rural women, widowed women, and lower socioeconomic class women. Conclusion. Depression is highly prevalent among women living with HIV which is still underdiagnosed and undertreated, and there is a need to incorporate mental health services as an integral component of HIV care. ","PeriodicalId":89950,"journal":{"name":"ISRN AIDS","volume":"2012 ","pages":"684972"},"PeriodicalIF":0.0,"publicationDate":"2012-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767188/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31747550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 20

High loss to followup and early mortality create substantial reduction in patient retention at antiretroviral treatment program in north-west ethiopia. 在埃塞俄比亚西北部，高随访损失和早期死亡率导致抗逆转录病毒治疗方案患者滞留率大幅下降。

ISRN AIDS Pub Date : 2012-06-14 eCollection Date: 2012-01-01 DOI: 10.5402/2012/721720

Mamo Wubshet, Yemane Berhane, Alemayehu Worku, Yigzaw Kebede, Ermias Diro

{"title":"High loss to followup and early mortality create substantial reduction in patient retention at antiretroviral treatment program in north-west ethiopia.","authors":"Mamo Wubshet, Yemane Berhane, Alemayehu Worku, Yigzaw Kebede, Ermias Diro","doi":"10.5402/2012/721720","DOIUrl":"https://doi.org/10.5402/2012/721720","url":null,"abstract":"Background. There has been a rapid scale up of antiretroviral therapy (ART) in Ethiopia since 2005. We aimed to evaluate mortality, loss to followup, and retention in care at HIV Clinic, University of Gondar Hospital, north-west Ethiopia. Method. A retrospective patient chart record analysis was performed on adult AIDS patients enrolled in the treatment program starting from 1 March 2005. We performed survival analysis to determine, mortality, loss to followup and retention in care. Results. A total of 3012 AIDS patients were enrolled in the ART Program between March 2005 and August 2010. At the end of the 66 months of the program initiation, 61.4% of the patients were retained on treatment, 10.4% died, and 31.4% were lost to followup. Fifty-six percent of the deaths and 46% of those lost to followup occurred in the first year of treatment. Male gender (adjusted hazard ratio (AHR) was 3.26; 95% CI: 2.19-4.88); CD4 count ≤200 cells/ μ L (AHR 5.02; 95% CI: 2.03-12.39), tuberculosis (AHR 2.91; 95% CI: 2.11-4.02); bed-ridden functional status (AHR 12.88; 95% CI: 8.19-20.26) were predictors of mortality, whereas only CD4 count <200 cells/ μ L (HR = 1.33; 95% CI: (0.95, 1.88) and ambulatory functional status (HR = 1.65; 95% CI: (1.22, 2.23) were significantly associated with LTF. Conclusion. Loss to followup and mortality in the first year following enrollment remain a challenge for retention of patients in care. Strengthening patient monitoring can improve patient retention AIDS care. ","PeriodicalId":89950,"journal":{"name":"ISRN AIDS","volume":"2012 ","pages":"721720"},"PeriodicalIF":0.0,"publicationDate":"2012-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767448/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31747551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 42

Clinicopathological Proficiency in the Diagnosis of Kaposi's Sarcoma. 卡波西肉瘤的临床病理诊断能力。

ISRN AIDS Pub Date : 2012-05-30 eCollection Date: 2012-01-01 DOI: 10.5402/2012/565463

Louis-Jacques van Bogaert

引用次数: 4