BJOG: An International Journal of Obstetrics & Gynaecology最新文献

{"title":"Stakeholder Perspectives on the Design of First-In-Human Trials for Artificial Amnion and Placenta Technology: A Qualitative Study","authors":"Angret de Boer, André Krom, Rania Kalaai, Marieke de Vries, Marije Hogeveen, Sylvia A. Obermann-Borst, Marijn Vermeulen, M. Beatrijs van der Hout-van der Jagt, Juliette S. van Haren, Peter Andriessen, Martine C. de Vries, Rosa Geurtzen, E. J. T. Verweij","doi":"10.1111/1471-0528.18189","DOIUrl":"https://doi.org/10.1111/1471-0528.18189","url":null,"abstract":"Artificial Amnion and Placenta Technology (AAPT), designed to improve outcomes in extreme prematurity, has shown promise in animal studies, with human trials anticipated soon. This study seeks to inform the responsible design of future trials by utilising insights from parents who experienced an (imminent) extremely premature birth and perinatal healthcare professionals (HCPs).","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"86 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143889449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerclage Reinforcement Following Primary Cerclage Procedure for Prevention of Preterm Birth: A Systematic Review and Meta-Analysis","authors":"Neel S. Iyer, Virali Patel, Amanda Roman, Lauren Clarfield, Stephen Contag, Rebecca Menzies, Vincenzo Berghella","doi":"10.1111/1471-0528.18185","DOIUrl":"https://doi.org/10.1111/1471-0528.18185","url":null,"abstract":"Transvaginal cerclage is an important intervention used to decrease the risk of preterm delivery.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143885065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disparities in Ultrasound Performance in Postmenopausal Bleeding","authors":"Ohad Rotenberg","doi":"10.1111/1471-0528.18196","DOIUrl":"https://doi.org/10.1111/1471-0528.18196","url":null,"abstract":"<h2> Conflicts of Interest</h2>\u0000<p>The author declares no conflicts of interest.</p>","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143880646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Periconceptual Maternal Diet and Miscarriage Risk","authors":"Yingjian Ye, Peng An","doi":"10.1111/1471-0528.18200","DOIUrl":"https://doi.org/10.1111/1471-0528.18200","url":null,"abstract":"Click on the article title to read more.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"85 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143880647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endometriosis and Contemporary Pain Science: Five “Simple Rules” for Managing Symptoms With Different Neurobiological Mechanisms","authors":"Paolo Vercellini, Giulia Emily Cetera, Noemi Salmeri, Paola Viganò, Edgardo Somigliana","doi":"10.1111/1471-0528.18201","DOIUrl":"https://doi.org/10.1111/1471-0528.18201","url":null,"abstract":"&lt;p&gt;Moreira and Oliveira highlight the shortcomings of the current management of endometriosis symptoms based on exclusively lesion-centred models, and promote patient categorisation according to an individual's predominant neurobiological mechanism, that is, nociceptive, neuropathic, or nociplastic pain [&lt;span&gt;1&lt;/span&gt;]. This should allow the tailored targeting of the different pain components, thus potentially optimising clinical outcomes.&lt;/p&gt;\u0000&lt;p&gt;We agree with the authors' conceptual framework [&lt;span&gt;2, 3&lt;/span&gt;] but, as accurately discriminating between the above pain phenotypes may not be straightforward, we propose five “simple rules” to guide inexperienced clinicians. Moreover, a comprehensive multimodal therapeutic approach is resource intensive, as physiotherapists, pain specialists, psychotherapists, gastroenterologists, urologists, and dieticians may be involved. Selected interventions, appropriately prescribed for patients with specific pain mechanisms, could avoid undue burden on already overstretched public health systems.&lt;/p&gt;\u0000&lt;p&gt;First, suspect early-onset endometriosis in adolescents complaining of painful periods and abdominopelvic pain (primarily nociceptive pain), as its prevalence in severely symptomatic teenagers is high even when ultrasound is negative [&lt;span&gt;2, 4&lt;/span&gt;]. Diagnostic delay promotes afferent hypersensitivity and fosters the transition from peripheral to central sensitisation [&lt;span&gt;2&lt;/span&gt;].&lt;/p&gt;\u0000&lt;p&gt;Second, at diagnosis, suppress recurrent ovulatory cycles with continuous bioequivalent oestradiol–progestogen combinations or progestogen monotherapies. Generally, ethinyl-oestradiol is pro-inflammatory, whereas progestogens are anti-inflammatory [&lt;span&gt;4&lt;/span&gt;]. Prompt secondary prevention could avoid disease progression, symptom worsening, and the transition from localised pelvic pain to widespread nociplastic pain.&lt;/p&gt;\u0000&lt;p&gt;Third, along with potentially different neurobiological mechanisms, evaluate symptom type. Menstrual pain should be relieved by establishing amenorrhoea; deep dyspareunia may benefit from the excision of deep lesions and treatment of pelvic floor hypertonicity.&lt;/p&gt;\u0000&lt;p&gt;Fourth, try a three-month course of a GnRH agonist or antagonist without ‘add-back’ therapy in non-responders to first-line medical treatment to differentiate between hormone-dependent (presumably mostly nociceptive) and hormone-independent (presumably mostly nociplastic) pain [&lt;span&gt;4&lt;/span&gt;]. This pharmacological test is practicable in any clinical setting, overcomes the potentially confusing uncertainties regarding progesterone resistance, and identifies the best candidates for additional interventions such as aerobic exercise, cognitive behavioural therapy, anti-inflammatory diet, pelvic floor rehabilitation, acupuncture, and non-hormonal pharmacological therapies. In GnRH analogue non-responders, the role of endometriosis as the sole or main pain trigger should be carefully reconsidered [&lt;span&gt;2, 4&lt;/span&gt;].&lt;/p&gt;\u0000&lt;p&gt;Fifth, admi","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143880645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postpartum Cardiovascular Health in African Women Following Pre-Eclampsia: A Prospective Cohort Study","authors":"Annettee Nakimuli, Emmy Okello, Annette Kesiiga, Moses Adroma, Jackline Akello, Sheila Nabweyambo, Musa Sekikubo, Imelda Namagembe, Robert Kayesubula, Ronald Galiwango, Brittany Jasper, Ashley Moffett, Catherine E. Aiken, Ian B. Wilkinson, Carmel M. McEniery","doi":"10.1111/1471-0528.18192","DOIUrl":"https://doi.org/10.1111/1471-0528.18192","url":null,"abstract":"To investigate the prevalence of hypertension and cardiovascular dysfunction 1 year postpartum in Black African women who experienced pre-eclampsia in a low-resource setting in Uganda.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143880590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pregnancy Outcome in Vascular Ehlers–Danlos Syndrome","authors":"Fang Chen, Dong‐Zhi Li","doi":"10.1111/1471-0528.18199","DOIUrl":"https://doi.org/10.1111/1471-0528.18199","url":null,"abstract":"","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143875872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dysmenorrhea and Adolescent Mental Health: A School-Based Cross-Sectional Study.","authors":"Pietro Gambadauro,Gergö Hadlaczky,Danuta Wasserman,Vladimir Carli","doi":"10.1111/1471-0528.18187","DOIUrl":"https://doi.org/10.1111/1471-0528.18187","url":null,"abstract":"OBJECTIVEWhile active monitoring of adolescent menstrual and mental health is advocated, research on their possible bidirectional relationship is limited. This study examines the association between adolescent dysmenorrhea and psychological symptoms.DESIGNCross-sectional study.SETTING116 schools in Stockholm, Sweden.SAMPLE1054 postmenarchal school girls (mean age 14.1 ± 0.7) randomly sampled from a population of 10 299 lower-secondary pupils in a school-based project.METHODSA self-report health survey assessed psychological symptoms using validated instruments. A multiple-choice item identified dysmenorrhea (menstrual pain affecting everyday life) and severe dysmenorrhea (dysmenorrhea that is hard to cope with).MAIN OUTCOME MEASURESPrevalence of dysmenorrhea and severe dysmenorrhea in girls with and without symptoms of depression (Beck's Depression Inventory-II score ≥ 20), anxiety (Generalised Anxiety Disorder 7-Item Scale score ≥ 10), self-injury (≥ 3 instances on a modified Deliberate Self-harm Inventory), and suicide ideation (recent serious thoughts/plans on the Paykel Suicide Scale).RESULTSOverall, 55.1% reported dysmenorrhea while 11.7% reported severe dysmenorrhea. Prevalence was 29%-34% higher among girls with psychological symptoms compared to those without. Severe dysmenorrhea was significantly more frequent among girls with any symptom (prevalence ratio [PR] 2.25; 95% CI 1.61, 3.13), depression (PR 2.60; 95% CI 1.86, 3.63), anxiety (PR 2.89; 95% CI 2.09, 4.00), self-injury (PR 1.87; 95% CI 1.29, 2.71), and suicide ideation (PR 1.75; 95% CI 1.18, 2.58) compared to girls without the same manifestations. These findings were consistent after adjustments for age, age of menarche, country of birth, and hormonal contraception.CONCLUSIONSThese findings emphasise the need for integrated approaches to adolescent menstrual and mental health care.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143872082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Post-Operative Pain After Pelvic Organ Prolapse Surgery (POPPOP): A Double Blind Randomised Multicentre Study to Assess the Effect of Local Anaesthesia During Vaginal Hysterectomy","authors":"Gans Thiagamoorthy, Anu Dua, George Araklitis, Rayan Mohamed-Ahmed, Jassimran Bansal, Faisal Karim, Cathy Davis, Rufus Cartwright, Vik Khullar, Aethele Khunda, Sushma Srikrishna, Dudley Robinson, Linda Cardozo","doi":"10.1111/1471-0528.18162","DOIUrl":"https://doi.org/10.1111/1471-0528.18162","url":null,"abstract":"To compare local anaesthetic with adrenaline (LAA) with normal saline for hydrodissection at vaginal hysterectomy.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"69 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143862259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immigration-Informed Pregnancy Care: A Call to Action","authors":"Rachel K. Feldman, Margaret M. Sullivan, Rose L. Molina","doi":"10.1111/1471-0528.18193","DOIUrl":"https://doi.org/10.1111/1471-0528.18193","url":null,"abstract":"<h2> Conflicts of Interest</h2>\u0000<p>The authors declare no conflicts of interest.</p>","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143857711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}