C. Vu, E. Porter, P. Fuentes, Thomas Guerrero, N. Chintalapati, R. Hales, Ranh, Voong, H. Sair, J. Grimm, M. Duhon, Lawrence, Kleinberg, T. Vannorsdall, K. Redmond
{"title":"THE PROCEEDINGS OF THE RADIATION ONCOLOGY SUMMIT: ACRO 2019","authors":"C. Vu, E. Porter, P. Fuentes, Thomas Guerrero, N. Chintalapati, R. Hales, Ranh, Voong, H. Sair, J. Grimm, M. Duhon, Lawrence, Kleinberg, T. Vannorsdall, K. Redmond","doi":"10.1007/s13566-019-00390-2","DOIUrl":"https://doi.org/10.1007/s13566-019-00390-2","url":null,"abstract":"","PeriodicalId":89815,"journal":{"name":"Journal of radiation oncology","volume":"17 1","pages":"1-37"},"PeriodicalIF":0.0,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84172428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Karivedu, Rishi Agarwal, S. Haque, Bicky Thapa, F. Fakhrejahani, P. Fu, G. Videtic, N. Sadraei
{"title":"Lymphopenia as a predictor of survival in chemoradiation-treated stage III non-small-cell lung cancer (NSCLC): a multi-center retrospective analysis","authors":"V. Karivedu, Rishi Agarwal, S. Haque, Bicky Thapa, F. Fakhrejahani, P. Fu, G. Videtic, N. Sadraei","doi":"10.1007/s13566-019-00384-0","DOIUrl":"https://doi.org/10.1007/s13566-019-00384-0","url":null,"abstract":"","PeriodicalId":89815,"journal":{"name":"Journal of radiation oncology","volume":"107 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79575164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Chan, Julian Johnson, A. Lazar, S. Braunstein, M. Descovich, A. Gottschalk, S. Yom
{"title":"Correction to: Stereotactic body radiation therapy for non-small cell lung cancer patients with prior history of thoracic surgery and/or radiation therapy: the influence of smoking, size, and central location on risk of complications","authors":"J. Chan, Julian Johnson, A. Lazar, S. Braunstein, M. Descovich, A. Gottschalk, S. Yom","doi":"10.1007/s13566-019-00377-z","DOIUrl":"https://doi.org/10.1007/s13566-019-00377-z","url":null,"abstract":"","PeriodicalId":89815,"journal":{"name":"Journal of radiation oncology","volume":"69 1","pages":"249"},"PeriodicalIF":0.0,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77977723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Adjuvant chemoradiation in resected gallbladder cancer: a prognostic index model for predicting overall survival","authors":"C. Sole, L. Vargas, V. Solé, F. Larsen, S. Sole","doi":"10.1007/s13566-019-00382-2","DOIUrl":"https://doi.org/10.1007/s13566-019-00382-2","url":null,"abstract":"","PeriodicalId":89815,"journal":{"name":"Journal of radiation oncology","volume":"33 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85113195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Falk, M. Aly, A. Berglund, T. Nordström, A. Valdman
{"title":"Salvage radiation therapy following radical prostatectomy in Stockholm County in 2008–2016","authors":"J. Falk, M. Aly, A. Berglund, T. Nordström, A. Valdman","doi":"10.1007/s13566-019-00393-z","DOIUrl":"https://doi.org/10.1007/s13566-019-00393-z","url":null,"abstract":"","PeriodicalId":89815,"journal":{"name":"Journal of radiation oncology","volume":"22 1","pages":"225 - 231"},"PeriodicalIF":0.0,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88853826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Parikh, A. Denittis, G. Marks, E. Zeger, David Cho, J. Marks
{"title":"Neoadjuvant chemotherapy and high-dose radiation using intensity-modulated radiotherapy followed by rectal sparing TEM for distal rectal cancer","authors":"K. Parikh, A. Denittis, G. Marks, E. Zeger, David Cho, J. Marks","doi":"10.1007/s13566-019-00389-9","DOIUrl":"https://doi.org/10.1007/s13566-019-00389-9","url":null,"abstract":"","PeriodicalId":89815,"journal":{"name":"Journal of radiation oncology","volume":"85 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86699473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Caesar E Ordoñez, Nicholas T Karonis, Kirk L Duffin, John R Winans, Ethan A DeJongh, Don F DeJongh, George Coutrakon, Nicole F Myers, Mark Pankuch, James S Welsh
{"title":"Fast In Situ Image Reconstruction for Proton Radiography.","authors":"Caesar E Ordoñez, Nicholas T Karonis, Kirk L Duffin, John R Winans, Ethan A DeJongh, Don F DeJongh, George Coutrakon, Nicole F Myers, Mark Pankuch, James S Welsh","doi":"10.1007/s13566-019-00387-x","DOIUrl":"https://doi.org/10.1007/s13566-019-00387-x","url":null,"abstract":"<p><strong>Objective: </strong>Proton beam therapy is an emerging modality for cancer treatment that, compared to X-ray radiation therapy, promises to provide better dose delivery to clinical targets with lower doses to normal tissues. Crucial to accurate treatment planning and dose delivery is knowledge of the water equivalent path length (WEPL) of each ray, or pencil beam, from the skin to every point in the target. For protons, this length is estimated from relative stopping power based on X-ray Hounsfield units. Unfortunately, such estimates lead to 3 to 4% uncertainties in the proton range prediction. Therefore, protons in the Bragg peak may overshoot (or undershoot) the desired stopping depth in the target causing tissue damage beyond the target volume. Recent studies indicate that tomographic imaging using protons has the potential to provide directly more accurate measurement of RSPs with significantly lower radiation dose than X-rays. We are currently working on a proton radiography system that promises to provide accurate two-dimensional (2D) images of WEPL values for protons that pass through the body. These will be suitable for positioning and range verification in daily treatments. In this study, we demonstrate that this system is capable of rapidly achieving such accurate images in clinically meaningful times.</p><p><strong>Methods: </strong>We have developed a software platform to characterize the potential performance of the prototype proton radiography system. We use Geant4 to simulate raw data detected by the device. An especially-written software - pRad - was written to process these data as they are received and uses iterative methods to generate radiographs. The software has been designed to generate a radiograph from a few million protons in under a minute after receiving the first proton from the device. We used a head phantom with known chemical compositions that could be modelled quite accurately in Geant4 simulations of proton radiographs. The radiographs are displayed as pixelated WEPL values displayed on a 2D gray scale image of WEPL values.</p><p><strong>Results: </strong>Rapid radiograph reconstruction of 3D phantoms using simulated proton pencil beams have been achieved with our software platform. On a modest desktop computer with a single central processing unit (CPU) and a single graphics processing unit (GPU), it takes about 11 seconds to reconstruct images using iterative linear algorithms to reconstruct a radiograph from 7.6 million protons. For the radiographic reconstructions of the head phantom described here, the mean WEPL errors, in the proton radiograph using a large majority of the pixels in the complete image were less than 1 mm when compared to images obtained without proton scattering and without detector resolution included.</p><p><strong>Conclusion: </strong>We have demonstrated, through computer simulations of proton irradiation of a pediatric head phantom using the newly built pRad detector and im","PeriodicalId":89815,"journal":{"name":"Journal of radiation oncology","volume":"8 2","pages":"185-198"},"PeriodicalIF":0.0,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s13566-019-00387-x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38573404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Kowalchuk, D. Trifiletti, S. Khandelwal, J. Larner, W. Watkins
{"title":"A risk model for lung complication combining radiation therapy and chronic obstructive pulmonary disease","authors":"R. Kowalchuk, D. Trifiletti, S. Khandelwal, J. Larner, W. Watkins","doi":"10.1007/s13566-019-00386-y","DOIUrl":"https://doi.org/10.1007/s13566-019-00386-y","url":null,"abstract":"","PeriodicalId":89815,"journal":{"name":"Journal of radiation oncology","volume":"15 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81262580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Newman, A. Sherry, Daniel W Byrne, E. Osmundson
{"title":"Stereotactic body radiotherapy versus conventional radiotherapy for early-stage small cell lung cancer","authors":"N. Newman, A. Sherry, Daniel W Byrne, E. Osmundson","doi":"10.1007/s13566-019-00395-x","DOIUrl":"https://doi.org/10.1007/s13566-019-00395-x","url":null,"abstract":"","PeriodicalId":89815,"journal":{"name":"Journal of radiation oncology","volume":"27 1","pages":"239-248"},"PeriodicalIF":0.0,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77107351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Danyaei, Hashem Khanbabaei, A. Teimoori, M. Tahmasbi, H. Shahbazian, Halime Mansoury Asl
{"title":"Effect of intermittent low-dose irradiation on the radiotherapy efficiency for MDA-MB-231 human breast adenocarcinoma cell line","authors":"A. Danyaei, Hashem Khanbabaei, A. Teimoori, M. Tahmasbi, H. Shahbazian, Halime Mansoury Asl","doi":"10.1007/s13566-019-00388-w","DOIUrl":"https://doi.org/10.1007/s13566-019-00388-w","url":null,"abstract":"","PeriodicalId":89815,"journal":{"name":"Journal of radiation oncology","volume":"13 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2019-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73221249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}