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Journal of radiation oncology最新文献

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A comprehensive analysis of clinical trials including both immunotherapy and radiation therapy 包括免疫治疗和放射治疗在内的临床试验的综合分析
Journal of radiation oncology Pub Date : 2018-05-10 DOI: 10.1007/s13566-018-0351-x
D. Boothe, J. W. Clyde, M. Christensen, Shiven B. Patel, S. Lloyd
{"title":"A comprehensive analysis of clinical trials including both immunotherapy and radiation therapy","authors":"D. Boothe, J. W. Clyde, M. Christensen, Shiven B. Patel, S. Lloyd","doi":"10.1007/s13566-018-0351-x","DOIUrl":"https://doi.org/10.1007/s13566-018-0351-x","url":null,"abstract":"","PeriodicalId":89815,"journal":{"name":"Journal of radiation oncology","volume":"103 1","pages":"223-232"},"PeriodicalIF":0.0,"publicationDate":"2018-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90906955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The albumin-bilirubin (ALBI) model in hepatocellular carcinoma (HCC) may better predict hepatic failure in patients with traditionally low-risk cirrhosis following definitive stereotactic body radiotherapy (SBRT) 肝细胞癌(HCC)的白蛋白-胆红素(ALBI)模型可以更好地预测传统低危肝硬化患者在明确立体定向放疗(SBRT)后的肝功能衰竭。
Journal of radiation oncology Pub Date : 2018-05-08 DOI: 10.1007/s13566-018-0354-7
S. Hasan, S. Abel, I. Jan, T. Uemura, N. Thai, A. Kirichenko
{"title":"The albumin-bilirubin (ALBI) model in hepatocellular carcinoma (HCC) may better predict hepatic failure in patients with traditionally low-risk cirrhosis following definitive stereotactic body radiotherapy (SBRT)","authors":"S. Hasan, S. Abel, I. Jan, T. Uemura, N. Thai, A. Kirichenko","doi":"10.1007/s13566-018-0354-7","DOIUrl":"https://doi.org/10.1007/s13566-018-0354-7","url":null,"abstract":"","PeriodicalId":89815,"journal":{"name":"Journal of radiation oncology","volume":"67 1","pages":"247-253"},"PeriodicalIF":0.0,"publicationDate":"2018-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72878022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Tolerability of sequential immune therapy and palliative radiotherapy to the cervical and thoracic spine 序贯免疫治疗和姑息性放疗对颈椎和胸椎的耐受性
Journal of radiation oncology Pub Date : 2018-05-03 DOI: 10.1007/s13566-018-0352-9
W. Arscott, A. Doucette, Pallavi Kumar, J. Plastaras, A. Maity, Joshua Jones
{"title":"Tolerability of sequential immune therapy and palliative radiotherapy to the cervical and thoracic spine","authors":"W. Arscott, A. Doucette, Pallavi Kumar, J. Plastaras, A. Maity, Joshua Jones","doi":"10.1007/s13566-018-0352-9","DOIUrl":"https://doi.org/10.1007/s13566-018-0352-9","url":null,"abstract":"","PeriodicalId":89815,"journal":{"name":"Journal of radiation oncology","volume":"1 1","pages":"233-239"},"PeriodicalIF":0.0,"publicationDate":"2018-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86548415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Factors predictive of neoadjuvant versus adjuvant chemoradiotherapy in locally advanced rectal cancer and the impact on overall survival 局部晚期直肠癌新辅助与辅助放化疗的预测因素及其对总生存期的影响
Journal of radiation oncology Pub Date : 2018-04-11 DOI: 10.1007/s13566-018-0350-y
A. Coffman, D. Boothe, Jonathan Frandsen, M. Gross, T. B. Pickron, C. Scaife, S. Lloyd
{"title":"Factors predictive of neoadjuvant versus adjuvant chemoradiotherapy in locally advanced rectal cancer and the impact on overall survival","authors":"A. Coffman, D. Boothe, Jonathan Frandsen, M. Gross, T. B. Pickron, C. Scaife, S. Lloyd","doi":"10.1007/s13566-018-0350-y","DOIUrl":"https://doi.org/10.1007/s13566-018-0350-y","url":null,"abstract":"","PeriodicalId":89815,"journal":{"name":"Journal of radiation oncology","volume":"5 1","pages":"213-222"},"PeriodicalIF":0.0,"publicationDate":"2018-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74285682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radical treatment of muscle-invasive bladder cancer—are options equal? 肌肉浸润性膀胱癌的根治性治疗是平等的吗?
Journal of radiation oncology Pub Date : 2018-03-29 DOI: 10.1007/s13566-018-0347-6
D. Fackrell, A. Marshall, P. Mistry, J. Dunn, M. D. De Santis, D. Ford, A. Zarkar
{"title":"Radical treatment of muscle-invasive bladder cancer—are options equal?","authors":"D. Fackrell, A. Marshall, P. Mistry, J. Dunn, M. D. De Santis, D. Ford, A. Zarkar","doi":"10.1007/s13566-018-0347-6","DOIUrl":"https://doi.org/10.1007/s13566-018-0347-6","url":null,"abstract":"","PeriodicalId":89815,"journal":{"name":"Journal of radiation oncology","volume":"37 1","pages":"181-186"},"PeriodicalIF":0.0,"publicationDate":"2018-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74943271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The use of stereotactic radiosurgery for benign spinal tumors: single institution experience 立体定向放射治疗脊柱良性肿瘤的应用:单一机构的经验
Journal of radiation oncology Pub Date : 2018-03-04 DOI: 10.1007/s13566-018-0345-8
D. Boyce-Fappiano, E. Elibe, M. Salim Siddiqui, I. Lee, J. Rock, F. Siddiqui
{"title":"The use of stereotactic radiosurgery for benign spinal tumors: single institution experience","authors":"D. Boyce-Fappiano, E. Elibe, M. Salim Siddiqui, I. Lee, J. Rock, F. Siddiqui","doi":"10.1007/s13566-018-0345-8","DOIUrl":"https://doi.org/10.1007/s13566-018-0345-8","url":null,"abstract":"","PeriodicalId":89815,"journal":{"name":"Journal of radiation oncology","volume":"16 1","pages":"157-165"},"PeriodicalIF":0.0,"publicationDate":"2018-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87164767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic factors affecting overall survival and local control in meningioma patients treated with radiotherapy or combined radiotherapy and surgery 影响脑膜瘤放疗或放疗与手术联合治疗患者总体生存和局部控制的预后因素
Journal of radiation oncology Pub Date : 2018-03-01 DOI: 10.1007/s13566-017-0334-3
Scott R. Silva, A. Sethi, V. Prabhu, D. Anderson, E. Melian
{"title":"Prognostic factors affecting overall survival and local control in meningioma patients treated with radiotherapy or combined radiotherapy and surgery","authors":"Scott R. Silva, A. Sethi, V. Prabhu, D. Anderson, E. Melian","doi":"10.1007/s13566-017-0334-3","DOIUrl":"https://doi.org/10.1007/s13566-017-0334-3","url":null,"abstract":"","PeriodicalId":89815,"journal":{"name":"Journal of radiation oncology","volume":"71 1","pages":"27-35"},"PeriodicalIF":0.0,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76302284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Absolute volume of active bone marrow and total bone marrow spared in anal cancer patients using intensity modulated proton versus volumetric arc therapy 使用强度调节质子与体积弧治疗的肛门癌患者的活性骨髓和总骨髓的绝对体积
Journal of radiation oncology Pub Date : 2018-03-01 DOI: 10.1007/s13566-017-0329-0
R. Prasad, C. Freese, M. Sudhoff, T. Meier, L. Lewis, A. Mascia, E. Wolf, J. Kharofa
{"title":"Absolute volume of active bone marrow and total bone marrow spared in anal cancer patients using intensity modulated proton versus volumetric arc therapy","authors":"R. Prasad, C. Freese, M. Sudhoff, T. Meier, L. Lewis, A. Mascia, E. Wolf, J. Kharofa","doi":"10.1007/s13566-017-0329-0","DOIUrl":"https://doi.org/10.1007/s13566-017-0329-0","url":null,"abstract":"","PeriodicalId":89815,"journal":{"name":"Journal of radiation oncology","volume":"15 1","pages":"69-75"},"PeriodicalIF":0.0,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84415976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Stereotactic body radiation therapy for non-small cell lung cancer patients with prior history of thoracic surgery and/or radiation therapy: the influence of smoking, size, and central location on risk of complications 有胸外科手术和/或放射治疗史的非小细胞肺癌患者的立体定向全身放射治疗:吸烟、大小和中心位置对并发症风险的影响
Journal of radiation oncology Pub Date : 2018-03-01 DOI: 10.1007/s13566-017-0330-7
J. Chan, Julian Johnson, A. Lazar, S. Braunstein, M. Descovich, A. Gottschalk, S. Yom
{"title":"Stereotactic body radiation therapy for non-small cell lung cancer patients with prior history of thoracic surgery and/or radiation therapy: the influence of smoking, size, and central location on risk of complications","authors":"J. Chan, Julian Johnson, A. Lazar, S. Braunstein, M. Descovich, A. Gottschalk, S. Yom","doi":"10.1007/s13566-017-0330-7","DOIUrl":"https://doi.org/10.1007/s13566-017-0330-7","url":null,"abstract":"","PeriodicalId":89815,"journal":{"name":"Journal of radiation oncology","volume":"63 1","pages":"53-61"},"PeriodicalIF":0.0,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72771988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The dosimetric effects of limited elective nodal irradiation in volumetric modulated arc therapy treatment planning for locally advanced non-small cell lung cancer. 局部晚期非小细胞肺癌容积调制弧治疗计划中有限的选择性结节照射的剂量学效应。
Journal of radiation oncology Pub Date : 2018-03-01 Epub Date: 2017-09-06 DOI: 10.1007/s13566-017-0327-2
Mark C Kenamond, R Alfredo Siochi, Malcolm D Mattes
{"title":"The dosimetric effects of limited elective nodal irradiation in volumetric modulated arc therapy treatment planning for locally advanced non-small cell lung cancer.","authors":"Mark C Kenamond, R Alfredo Siochi, Malcolm D Mattes","doi":"10.1007/s13566-017-0327-2","DOIUrl":"10.1007/s13566-017-0327-2","url":null,"abstract":"<p><strong>Objective: </strong>Contemporary radiotherapy guidelines for locally advanced non-small cell lung carcinoma (LA-NSCLC) recommend omitting elective nodal irradiation, despite the fact that evidence supporting this came primarily from older reports assessing comprehensive nodal coverage using 3D conformal techniques. Herein, we evaluated the dosimetric implications of the addition of limited elective nodal irradiation (LENI) to standard involved field irradiation (IFI) using volumetric modulated arc therapy (VMAT) planning.</p><p><strong>Method: </strong>Target volumes and organs-at-risk (OARs) were delineated on CT simulation images of 20 patients with LA-NSCLC. Two VMAT plans (IFI and LENI) were generated for each patient. Involved sites were treated to 60 Gy in 30 fractions for both IFI and LENI plans. Adjacent uninvolved nodal regions, considered high risk based on the primary tumor site and extent of nodal involvement, were treated to 51 Gy in 30 fractions in LENI plans using a simultaneous integrated boost approach.</p><p><strong>Results: </strong>All planning objectives for PTVs and OARs were achieved for both IFI and LENI plans. LENI resulted in significantly higher esophagus <i>D</i><sub>mean</sub> (15.3 vs. 22.5 Gy, <i>p</i> < 0.01), spinal cord <i>D</i><sub>max</sub> (34.9 vs. 42.4 Gy, <i>p</i> = 0.02) and lung <i>D</i><sub>mean</sub> (13.5 vs. 15.9 Gy, <i>p</i> = 0.02), <i>V</i><sub>20</sub> (23.0 vs. 27.9%, <i>p</i> = 0.03), and <i>V</i><sub>5</sub> (52.6 vs. 59.4%, <i>p</i> = 0.02). No differences were observed in heart parameters. On average, only 32.2% of the high-risk nodal volume received an incidental dose of 51 Gy when untargeted in IFI plans.</p><p><strong>Conclusion: </strong>The addition of LENI to VMAT plans for LA-NSCLC is feasible, with only modestly increased doses to OARs and marginal expected increase in associated toxicity.</p>","PeriodicalId":89815,"journal":{"name":"Journal of radiation oncology","volume":"7 1","pages":"45-51"},"PeriodicalIF":0.0,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135255/pdf/nihms945915.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36496370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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