ISRN orthopedics最新文献

{"title":"Shoelace wound closure for the management of fracture-related fasciotomy wounds.","authors":"Abdelsalam Eid,&nbsp;Mohamed Elsoufy","doi":"10.5402/2012/528382","DOIUrl":"https://doi.org/10.5402/2012/528382","url":null,"abstract":"<p><p>Background. Compartment syndrome is a serious complication that might occur following fractures. The treatment of choice is emergent fasciotomy of all the involved muscle compartments to lower the compartment pressure. The classic management of fasciotomy wounds was split thickness skin graft. Patients and Methods. Seventeen patients with fracture-related compartment syndrome were managed by fasciotomy in the Orthopaedic Casualty Unit of our university hospital. The fractures included four femoral fractures and 13 fractures of the tibia and fibula. Results. All fasciotomy wounds healed eventually. Wound closure occurred from the corners inward. The skin closure was obtained at an overall average of 4.2 tightening sessions (range 3-7). Fracture healing occurred at an average of 15.4 weeks (range 12 to 22 weeks). No major complications were encountered in this series. Conclusion. Closure of fasciotomy wounds by dermatotraction could be performed in a staged fashion, using inexpensive equipment readily available in any standard operating room, until skin was approximated enough to heal either through delayed primary closure or secondary healing. </p>","PeriodicalId":89787,"journal":{"name":"ISRN orthopedics","volume":"2012 ","pages":"528382"},"PeriodicalIF":0.0,"publicationDate":"2012-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2012/528382","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32465716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Necrosis of Staphylococcus aureus by the Electrospun Fe- and Ag-Doped TiO2 Nanofibers.","authors":"Asem Aboelzahab,&nbsp;Abdul-Majeed Azad,&nbsp;Vijay Goel","doi":"10.5402/2012/763806","DOIUrl":"https://doi.org/10.5402/2012/763806","url":null,"abstract":"<p><p>Postsurgery infections cause prolonged hospitalization, incurring increased patient and hospital costs, making it increasingly vital to develop an effective solution for the mitigation and elimination of infection buildup at these sites. Incorporation of a bactericidal device at the infection-prone sites provides the capability of attacking bacterial growth even after the patient has left the hospital. Polycrystalline titanium dioxide (TiO2) is photoactive and possesses antibacterial properties that can mitigate the onset of these infections and aid in wound healing. In this work, TiO2 nanofibers were synthesized by electrospinning. Doping with iron as well as with silver (5 wt% and 1 wt%, resp.) was also carried out to increase their effectiveness towards bactericidal properties. The electrospun fibers were processed and tested in the presence of light in the suspensions of methicillin-susceptible Staphylococcus aureus (MSSA) bacteria, which are the leading infection-inducing bacteria among hospital patients. It was found that upon brief activation (cf. 30 s) by an infrared laser source, greater than 90% of the S. aureus was rendered inactive within cf. 10 min. of exposure, thereby showing the potential of titania nanofibers for effective mitigation of infection. </p>","PeriodicalId":89787,"journal":{"name":"ISRN orthopedics","volume":"2012 ","pages":"763806"},"PeriodicalIF":0.0,"publicationDate":"2012-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2012/763806","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32465720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gender differences in pain perception and functional ability in subjects with knee osteoarthritis.","authors":"M Elboim-Gabyzon,&nbsp;N Rozen,&nbsp;Y Laufer","doi":"10.5402/2012/413105","DOIUrl":"https://doi.org/10.5402/2012/413105","url":null,"abstract":"<p><p>Background. There is no consensus regarding gender-related differences in pain intensity and functional abilities among patients with knee osteoarthritis (OA). Objective. Determine gender-related differences in pain intensity and functional ability among subjects with knee OA, as assessed by a self-report questionnaire and by performance-based tests. Methods. Sixty-three subjects with symptomatic knee pain due to OA were included in this study. The outcome measures were self-reported knee pain intensity and physical function (WOMAC), as well as three performance-based functional assessments: time up and go test, a 10-meter walk test, and stair negotiation. Independent sample t-tests were performed to determine gender differences. Level of significance was set at P ≤ 0.05. Results. Female subjects reported higher levels of knee pain and lower functional performance. In contrast, no significant gender-related differences were determined in any of the performance-based measures. Conclusion. The results indicate that the two types of functional ability measures may address different constructs of functional ability. Self-reported ability, particularly in the female subjects, may be influenced by psychological aspects associated with chronic pain. Rehabilitation programs should consider the underlying mechanisms of the patients' performance limitations in order to address the specific needs of each individual patient. </p>","PeriodicalId":89787,"journal":{"name":"ISRN orthopedics","volume":"2012 ","pages":"413105"},"PeriodicalIF":0.0,"publicationDate":"2012-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2012/413105","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32464197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioelectric activity in the suprachiasmatic nucleus-pineal gland system in children with adolescent idiopathic scoliosis.","authors":"Dmitry Yu Pinchuk,&nbsp;Sergey S Bekshaev,&nbsp;Svetlana A Bumakova,&nbsp;Mikhail G Dudin,&nbsp;Olga D Pinchuk","doi":"10.5402/2012/987095","DOIUrl":"https://doi.org/10.5402/2012/987095","url":null,"abstract":"<p><p>The purpose of this work is to identify a role of the pineal gland/suprachiasmatic nucleus system in adolescent idiopathic scoliosis (AIS) aetiology and pathogenesis. To analyze electroencephalograms of 292 children with AIS and in 46 healthy subjects, a processing method was used to assess three-dimensional coordinates of electric equivalent dipole sources (EEDSs) within the brain. Amounts of EEDSs in the pineal gland and suprachiasmatic nucleus (SCN) area were assessed in different age groups and during the progress of orthopaedic pathology. It was shown that children with AIS, compared with healthy children, were characterized by a higher level of electric activity (as judged by EEDS values) in the pineal gland area. It was also revealed that the number of EEDS in the pineal gland area increases significantly with increased severity of spinal deformation, while their number in the suprachiasmatic nucleus (SCN) area decreases compared with the number in healthy peers. Changes in electric activity and changes in the pineal gland and SCN area suggest that mechanisms of AIS aetiology and pathogenesis involve functional disturbances in brain areas responsible for the formation and maintenance of normal biorhythms, including osteogenesis and bone growth. </p>","PeriodicalId":89787,"journal":{"name":"ISRN orthopedics","volume":"2012 ","pages":"987095"},"PeriodicalIF":0.0,"publicationDate":"2012-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2012/987095","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32465721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of the juncturae tendinum in preventing radial subluxation of the extensor communis tendons after ulnar sagittal band rupture: a cadaveric study.","authors":"N Greville Farrar,&nbsp;Amrit Kundra","doi":"10.5402/2012/597681","DOIUrl":"https://doi.org/10.5402/2012/597681","url":null,"abstract":"<p><p>Background. Radial subluxation of the extensor communis tendons at the metacarpophalangeal (MCP) joints is a rarely reportedvinjury. These injuries have proved difficult to reproduce in cadaveric studies and have a low biomechanical likelihood of occurrence due to the ulnar direction of pull of the extensor communis tendons. It has been suggested that the juncturae tendinum may have a stabilising role, preventing radial subluxation after ulnar sagittal band rupture; however this has not been established. Methods. 40 cadaveric digits were dissected to reveal the extensor mechanism around the MCP joints. The ulnar sagittal bands were released and then the juncturae tendinum divided, in stages, before observing for radial subluxation or dislocation during finger flexion. Results. Radial subluxation of the extensor tendon was observed in only one digit after complete ulnar sagisttal band release. When all the fingers were flexed, after the juncturae tendinorum were divided, four additional tendons subluxed radially and a fifth tendon dislocated in this direction. When the digits were then flexed individually, there were eight unstable tendons in total. Conclusions. The juncturae tendinum appear to have a role in stabilising the extensor communis tendons at the MCP joints and preventing radial subluxation after ulnar sagittal band rupture. </p>","PeriodicalId":89787,"journal":{"name":"ISRN orthopedics","volume":"2012 ","pages":"597681"},"PeriodicalIF":0.0,"publicationDate":"2012-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2012/597681","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32465717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An assessment of the chondroprotective effects of intra-articular application of statin and tetracycline on early-stage experimental osteoarthritis.","authors":"Mustafa Dinc,&nbsp;Muhammed Sadik Bilgen,&nbsp;Abdullah Kucukalp,&nbsp;Omer Faruk Bilgen","doi":"10.5402/2012/182097","DOIUrl":"https://doi.org/10.5402/2012/182097","url":null,"abstract":"<p><p>Objectives. To compare the effects of intra-articular application of statin and tetracyclines on cartilage and synovial tissue on experimental osteoarthritis. Methods. Osteoarthritis was created in 30 rabbits of 3 groups. The control group received saline intra-articularly, statin group, atorvastatin and the tetracycline group, doxycycline once a week for 3 weeks. Chondral and synovial tissues were evaluated macroscopically and histopathologically. Results. Macroscopic evaluation determined mean values of control group 3.0, statin group 0.56, and tetracycline group 2.5. Histopathological evaluations determined mean values; femoral medial condyle cartilage tissue, control group, 14.60 ± 1.00, statin group 2.20 ± 1.30, tetracycline group 12.7 ± 5.39: tibia medial plateau, control group, 14.33 ± 8.68, statin group 2.89 ± 1.96, tetracycline group, 15.90 ± 7.03: synovial tissue, control group 12.22 ± 3.63, statin group 4.33 ± 2.69, tetracycline group 10.70 ± 2.62. Average values of synovial tissue cell layer thickness were control group 14.46 ± 2.35 μm, statin group 10.56 ± 1.01 μm, tetracycline group 12.80 ± 0.79 μm. All measurements showed statistically significant differences between statin and control groups (P < 0.05) but not between tetracycline and control groups (P > 0.05). Conclusions. Tetracycline has little effect due to chemical modification requirement, and the effect is dose dependent. Statins have chondroprotective effects, so may become a novel therapeutic agent in osteoarthritis management after chemical processing. </p>","PeriodicalId":89787,"journal":{"name":"ISRN orthopedics","volume":"2012 ","pages":"182097"},"PeriodicalIF":0.0,"publicationDate":"2012-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2012/182097","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32464194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the accuracy of bone resection by cutting blocks in patient-specific total knee replacements.","authors":"Cheng Hong Yeo,&nbsp;A Jariwala,&nbsp;N Pourgiezis,&nbsp;A Pillai","doi":"10.5402/2012/509750","DOIUrl":"https://doi.org/10.5402/2012/509750","url":null,"abstract":"<p><p>Introduction. The key to a successful total knee arthroplasty (TKA) is the restoration of the mechanical axis with balanced flexion and extension gaps. Patient-specific cutting block technique has been the latest development in total knee arthroplasty. This technique uses a magnetic resonance image (MRI) of the patient's symptomatic knee to create bone models and cutting jigs. This study was designed to evaluate the intraoperative accuracy of the patient-specific cutting block as compared to the preoperative template. Methods. Visionaire (Smith and Nephew, Genesis 2 Knee Arthroplasty) patient-specific TKA was used in all patients. An independent research officer was responsible for measuring all the resected articular surfaces of femur and tibia during surgery and compared it to the cutting block manufactured according to the preoperative template. Seven different measurements from each patient were obtained; four different measurements from the femur and three from the tibia were recorded. The differences between the actual resections made intraoperatively, as compared to the original pre-operative templates, were noted as the error. The surgical team was blinded to the measurements of the resections and the calculations of the errors. Results. Twenty-six Visionaire patient-specific TKA were included in the study. A total of 182 readings of bone resections made intraoperatively (seven for each patient). Eighty five percent of all collected readings were below the error margin of ≤1.5 mm. Size of resection had no effect on the error margin. All patients had satisfactory post-operative alignment, and at discharge all 26 patients achieved more than 90° of knee flexion. Conclusion. This observational study provides evidence that patient-specific TKA is comparable to other forms of TKA and may have some distinct advantages. In addition, we have shown that the cutting blocks are able to consistently deliver accurate cuts that are reproducible. We recommend intra-operative measurement of the bone resection and its comparison with the cutting block as a routine surgical step to confirm the MRI scan data, block placement, and instant validation of the bony resection before implant placement. </p>","PeriodicalId":89787,"journal":{"name":"ISRN orthopedics","volume":"2012 ","pages":"509750"},"PeriodicalIF":0.0,"publicationDate":"2012-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2012/509750","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32465715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of trochanter-shaft angle in selection of entry site in antegrade intramedullary femoral nail.","authors":"O P Lakhwani","doi":"10.5402/2012/431374","DOIUrl":"https://doi.org/10.5402/2012/431374","url":null,"abstract":"<p><p>Background. Selection of entry point for nail insertion is controversial and lack firm anatomical basis. The study is done to analyze the proximal anthropometry of femur and measure the Trochanter-Shaft Angle to find its relation and significance in selection of entry point for antegrade uniplanar femoral nail. Materials and Methods. Study involves the measurement of trochanter-shaft angle and other anthropometric measurements on 50 dry femora and on digital radiogram. Results. Trochanter-Shaft angle ranges between 5-17 degrees in anthropometric study and 4-14 degrees in radiological study. Over all in 27 cases (54%), exit points of reamur fall in the middle quadrant in sagittal and coronal plane, which corresponds to the T-S angle of 6-12 degrees. Discussion and Conclusion. Proximal femoral Anthropometry and Trochanter-shaft angle is variable; hence it is difficult to fix any anatomical point as a universal entry point for antegrade femoral nail insertion. Trochanter shaft angle (TSA) can be well accessed radiologically and serve as a guide for selection of proper entry point.for safe nail insertion. Clinical Relevance. Individual variations in the proximal femur anatomy for safe nail insertion can be correlated with Trochanter shaft angle to serve safe entry site. </p>","PeriodicalId":89787,"journal":{"name":"ISRN orthopedics","volume":"2012 ","pages":"431374"},"PeriodicalIF":0.0,"publicationDate":"2012-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2012/431374","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32464198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of skeletal muscle injury: a review.","authors":"L Baoge,&nbsp;E Van Den Steen,&nbsp;S Rimbaut,&nbsp;N Philips,&nbsp;E Witvrouw,&nbsp;K F Almqvist,&nbsp;G Vanderstraeten,&nbsp;L C Vanden Bossche","doi":"10.5402/2012/689012","DOIUrl":"https://doi.org/10.5402/2012/689012","url":null,"abstract":"<p><p>Skeletal muscle injuries are the most common sports-related injuries and present a challenge in primary care and sports medicine. Most types of muscle injuries would follow three stages: the acute inflammatory and degenerative phase, the repair phase and the remodeling phase. Present conservative treatment includes RICE (rest, ice, compression, elevation), nonsteroidal anti-inflammatory drugs (NSAIDs) and physical therapy. However, if use improper, NSAIDs may suppress an essential inflammatory phase in the healing of injured skeletal muscle. Furthermore, it remains controversial whether or not they have adverse effects on the healing process or on the tensile strength. However, several growth factors might promote the regeneration of injured skeletal muscle, many novel treatments have involved on enhancing complete functional recovery. Exogenous growth factors have been shown to regulate satellite cell proliferation, differentiation and fusion in myotubes in vivo and in vitro, TGF-β1 antagonists behave as inhibitors of TGF-β1. They prevent collagen deposition and block formation of muscle fibrosis, so that a complete functional recovery can be achieved. </p>","PeriodicalId":89787,"journal":{"name":"ISRN orthopedics","volume":"2012 ","pages":"689012"},"PeriodicalIF":0.0,"publicationDate":"2012-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2012/689012","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32465719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Geometric Structure of 3D Spinal Curves: Plane Regions and Connecting Zones.","authors":"E Berthonnaud,&nbsp;R Hilmi,&nbsp;J Dimnet","doi":"10.5402/2012/840426","DOIUrl":"https://doi.org/10.5402/2012/840426","url":null,"abstract":"<p><p>This paper presents a new study of the geometric structure of 3D spinal curves. The spine is considered as an heterogeneous beam, compound of vertebrae and intervertebral discs. The spine is modeled as a deformable wire along which vertebrae are beads rotating about the wire. 3D spinal curves are compound of plane regions connected together by zones of transition. The 3D spinal curve is uniquely flexed along the plane regions. The angular offsets between adjacent regions are concentrated at level of the middle zones of transition, so illustrating the heterogeneity of the spinal geometric structure. The plane regions along the 3D spinal curve must satisfy two criteria: (i) a criterion of minimum distance between the curve and the regional plane and (ii) a criterion controlling that the curve is continuously plane at the level of the region. The geometric structure of each 3D spinal curve is characterized by the sizes and orientations of regional planes, by the parameters representing flexed regions and by the sizes and functions of zones of transition. Spinal curves of asymptomatic subjects show three plane regions corresponding to spinal curvatures: lumbar, thoracic and cervical curvatures. In some scoliotic spines, four plane regions may be detected. </p>","PeriodicalId":89787,"journal":{"name":"ISRN orthopedics","volume":"2012 ","pages":"840426"},"PeriodicalIF":0.0,"publicationDate":"2012-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2012/840426","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32510262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}